Search clinical trials for: vasoocclusive crisis

Total 546 results

GlycoMimetics Incorporated

Completed

Study of GMI-1070 for the Treatment of Sickle Cell Pain Crisis

Sickle Cell Disease | Vaso-occlusive Crisis | Pain Crisis

United States, Canada
University of Birmingham

Unknown

Outcomes of Elective Cancer Surgery During the COVID-19 Pandemic Crisis (CovidSurg-Can)

COVID-19 | Cancer | Surgery | Coronavirus

Spain
Wefight

Completed

Distress in Crisis Situations During COVID-19

Stress, Psychological

France
Abramson Cancer Center of the University of Pennsylvania

Terminated

Rapamycin in With High-Dose Etoposide and Cytarabine in Relapsed/Refractory Aggressive Lymphoid Malignancies (UPCC 25406)

Lymphoblastic Leukemia | Burkitt's Lymphoma | CML | ALL

United States
Hôpital Raymond Poincaré
Dominique FLETCHER MD-PhD; Clement DURET MD; Guillaume GERI MD-PhD

Unknown

Burnout Among Caregivers Facing COVID-19 Health Crisis at a Non-conventional Intensive Care Unit Compared to a Conventional Intensive Care Unit

COVID-19 | Stress, Psychological | Intensive Care Unit | Burnout, Caregiver
Ottawa Hospital Research Institute

Completed

Impact of Unexpected Death in Simulation: Skill Retention, Stress and Emotions

Stress | Crisis Resource Management (CRM) Skills | Advanced Cardiovascular Life Support (ACLS) Skills

Canada
Express Collaborative

Unknown

Critical Delays in Cardiopulmonary Resuscitation During Simulated Obstetric Crisis: a Prospective Observational Study.

Maternal Death During Childbirth

Canada
Nirmish Shah
Bristol-Myers Squibb

Terminated

Apixaban in Patients With Sickle Cell Disease

Sickle Cell Disease | Vaso-occlusive Crisis | Reduction in Hospitalizations

United States
Mallinckrodt
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Nitric Oxide Inhalation to Treat Sickle Cell Pain Crises

Anemia, Sickle Cell

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Donor Lymphocyte Infusion in Treating Patients With Persistent, Relapsed, or Progressing Cancer After Donor Hematopoietic Cell Transplant

Recurrent Hodgkin Lymphoma | Recurrent Adult Acute Myeloid Leukemia | Recurrent Adult Acute Lymphoblastic Leukemia | Recurrent Non-Hodgkin Lymphoma | Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Recurrent Plasma Cell Myeloma

United States, Germany, Italy
Reprixys Pharmaceutical Corporation
National Heart, Lung, and Blood Institute (NHLBI); Food and Drug Administration...

Completed

Study to Assess Safety and Impact of SelG1 With or Without Hydroxyurea Therapy in Sickle Cell Disease Patients With Pain Crises (SUSTAIN)

Sickle Cell Disease

United States, Brazil, Jamaica
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Tacrolimus and Mycophenolate Mofetil in Preventing Graft-Versus-Host Disease in Patients Who Have Undergone Total-Body Irradiation With or Without Fludarabine Phosphate Followed by Donor Peripheral Blood Stem Cell Transplant for Hematologic Cancer

Primary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia | Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell... and other conditions

United States, Italy
University of Manitoba
Queen's University

Completed

Action-based Cognitive Remediation for First Episode Psychosis

Cognitive Impairment | Psychosis

Canada
Astex Pharmaceuticals, Inc.
Eisai Inc.

Completed

Phase II Trial of Decitabine in Patients With Chronic Myelogenous Leukemia Blast Phase Who Are Refractory to Imatinib Mesylate (Gleevec)

Chronic Myelogenous Leukemia

United States, Canada
National Heart, Lung, and Blood Institute (NHLBI)
Mallinckrodt

Completed

Nitric Oxide and Transfusion Therapy for Sickle Cell Patients With Pulmonary Hypertension

Sickle Cell Anemia | Pulmonary Hypertension

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Therapeutic Application of Intravascular Nitrite for Sickle Cell Disease

Sickle Cell Anemia

United States
Memorial Sloan Kettering Cancer Center
The City College of New York; North Jersey Community Research Initiative; Gay... and other collaborators

Completed

Tobacco Assessment and Intervention With Low-Income Persons Living With HIV-AIDS (PLWHA) in Community-Based AIDS Service Organizations

Tobacco Cessation | HIV | AIDS

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Tacrolimus and Mycophenolate Mofetil With or Without Sirolimus in Preventing Acute Graft-Versus-Host Disease in Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer

Previously Treated Myelodysplastic Syndrome | Recurrent Adult Acute Myeloid Leukemia | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma | Recurrent Adult Lymphoblastic... and other conditions

United States, Germany, Denmark
Assistance Publique - Hôpitaux de Paris

Unknown

Music Therapy in Sickle Cell Disease Vaso-occlusive Crisis (MUSICODREP)

Vaso-occlusive Crisis

France
Wuerzburg University Hospital

Unknown

Predisposing Factors for the Incidence of Adrenal Crisis (PIA)

Adrenal Insufficiency

Germany
VA Nebraska Western Iowa Health Care System

Completed

Role of Apathy in the Effectiveness of Weight Loss Interventions

Obesity | Apathy

United States
Eisai GmbH

Completed

ZEDEBAC: Zebinix Effects in Dependency of Baseline Conditions

Focal Epilepsy

Germany
NorthShore University HealthSystem

Completed

Effect of an Electronic Cognitive Aid Versus Static Cognitive Aid on the Management of a Simulated Crisis

Cognitive Aids

United States
Connecticut Children's Medical Center

Terminated

Low-Dose Ketamine Infusion for Children With Sickle Cell Disease-Related Pain

Sickle Cell Disease

United States
University of Chicago
National Cancer Institute (NCI)

Completed

Donor T Cells After Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent... and other conditions

United States
Brigham and Women's Hospital
Massachusetts General Hospital; Beth Israel Deaconess Medical Center; Anesthesia...

Completed

Using Emergency Manuals During Interprofessional Crisis Management: Are There Unintended Consequences? (EM)

Safety Issues

United States
University of Wisconsin, Madison

Completed

Treatment of Symptoms After Stent Placement for Urinary Tract Obstruction

Ureteral Obstruction

United States
Groupe Hospitalier de la Rochelle Ré Aunis

Terminated

Protective Factors Against Elderly Suicide (ProFAES)

Suicide, Attempted | Suicide Gesture

France
University of Mississippi Medical Center

Completed

A Phase 1 Study of Continuous Intravenous L-citrulline During Sickle Cell Pain Crisis or Acute Chest Syndrome

Sickle Cell Disease

United States
National Institute of Allergy and Infectious Diseases...
Novartis Vaccines; HIV Vaccine Trials Network; IPPOX Foundation

Completed

Safety and Immune Response to a Clade C DNA HIV Vaccine (HVTN111)

HIV Infections

South Africa, Zambia, Tanzania
City of Hope Medical Center

Terminated

Deferasirox for Treating Patients Who Have Undergone Allogeneic Stem Cell Transplant and Have Iron Overload

Primary Myelofibrosis | Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Iron Overload | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell... and other conditions

United States
Eli Lilly and Company

Terminated

A Study for Patients With Acute Leukemia

Acute Leukemia

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Infection Prophylaxis and Management in Treating Cytomegalovirus (CMV) Infection in Patients With Hematologic Malignancies Previously Treated With Donor Stem Cell Transplant

Primary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia | Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid... and other conditions

United States
University of Manitoba
Manitoba Medical Service Foundation; Winnipeg Foundation

Completed

The Effectiveness of Psychotherapy Classes in Reducing Suicidal Ideation

Suicidal Ideation

Canada
Queen Mary University of London

Completed

Optimizing Vitamin D Status in Children With Wheeze / Asthma (OPTIVIT) (OPTIVIT)

Wheezing | Asthmatic Crisis

United Kingdom
University of Oklahoma
The Children's Hospital at OU Medical Center

Completed

Music Therapy: Sickle Cell and Pain Crisis

Functional Abdominal Pain | Sickle Cell Crisis | Patients Followed by the Pain Team
Centre d'Investigation Clinique et Technologique...

Completed

Incidence and Risk of Influenza in Myasthenic Patients

Upper Respiratory Infection | Myasthenic Crisis
Jeffrey Glassberg
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Inhaled Mometasone to Reduce Painful Episodes in Patients With Sickle Cell Disease (IMPROVE)

Sickle Cell Disease

United States
Northwestern University

Terminated

Metformin+Cytarabine for the Treatment of Relapsed/Refractory AML

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia With Maturation (M2) | Adult Acute... and other conditions

United States
University Hospital Inselspital, Berne
University of Washington; Ludwig-Maximilians - University of Munich; Aalborg...

Completed

Genetic Determinants of Amitriptyline Efficiency for Pain Treatment - Part II

Chronic Pain

Switzerland
Case Comprehensive Cancer Center

Completed

Donor Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell... and other conditions

United States
Sunnybrook Health Sciences Centre

Terminated

Family Focused Therapy for Teens at Risk for Bipolar Disorder

Bipolar Disorder

Canada
Ottawa Hospital Research Institute

Completed

Learning Crisis Resource Management: Practicing Versus Observational Role in Simulation Training

Focus of Study is Teaching Crisis Resource Management

Canada
Université Paris-Sud

Completed

Comparison of Learning Outcomes Between the Roles of Learner During an Immersive Simulation

One-day Training Simulation With 4 Immersive Scenarios

France
University of Illinois at Chicago

Completed

Fludarabine Based Conditioning for Allogeneic Transplantation for Advanced Hematologic Malignancies

Acute Myeloid Leukemia | Polycythemia Vera | Multiple Myeloma | Myelofibrosis | Acute Leukemia | Chronic Myelogenous Leukemia | Aplastic Anemia | Myeloproliferative Disorder | Hodgkin's Disease | Malignant Lymphoma | Lymphocytic Leukemia

United States
Nationwide Children's Hospital

Completed

The Use of Warmed Saline in Vaso-occlusive Episodes

Sickle Cell Disease | Sickle Cell Crisis
EDDC (Experimental Drug Development Centre), A*STAR...
Chiltern International Inc.

Withdrawn

Evaluation of ETC-1907206 With Dasatinib in Advanced Haematologic Malignancies

Ph+ Acute Lymphoblastic Leukemia (Ph+ALL) | Ph- Acute Lymphoblastic Leukemia (Ph-ALL) | Chronic Myeloid Leukemia Accelerated Phase (CML-AP, Ph+) | Chronic Myeloid Leukemia Blast Crisis (CML-BC, Ph+)

United States, Singapore
Seoul National University Hospital
National Cancer Center, Korea; Samsung Medical Center; Asan Medical Center; Ewha...

Completed

Efficacy of a Smart Management Strategy for Health (SMASH) Program for Overcoming Cancer Crisis and Growing Positively

Stomach Neoplasms | Breast Neoplasms | Lung Neoplasms | Colorectal Neoplasms

Korea, Republic of
UCB Pharma

Completed

A Dose-ranging Study With Brivaracetam in Patients From 16 to 65 Years With Refractory Partial Onset Seizures.

Epilepsy

United States, Mexico, India, Brazil
University Hospital, Montpellier

Completed

Physiotherapy Efficiency on Child Asthma

Child | Asthma Crisis

France

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