Search clinical trials for: Rod-Cone Degeneration

Total 3942 results

Novartis Pharmaceuticals

Completed

Comparison of Safety, Effectiveness and Quality of Life Outcomes Between Labeled Versus "Treat and Extend" Regimen in Turkish Patients With Choroidal Neovascularisation Due to Age-related Macular Degeneration (AMD) (SALUTE)

Age-related Macular Degeneration

Turkey
Allergan

Completed

Retrospective Data Collection Study in Patients Receiving Two or More OZURDEX® Injections for Macular Oedema Secondary to Retinal Vein Occlusion

Retinal Vein Occlusion | Macular Oedema

Belgium
Regeneron Pharmaceuticals
Bayer

Completed

Vascular Endothelial Growth Factor (VEGF) Trap-Eye: Investigation of Efficacy and Safety in Central Retinal Vein Occlusion (CRVO)

Macular Edema Secondary to Central Retinal Vein Occlusion

United States, Canada, Colombia, Israel, India
Merck Sharp & Dohme LLC

Withdrawn

A Study of Denufosol Tetrasodium Intravitreal Injection in Subjects With Post Cataract Extraction Macular Edema

Macular Edema, Cystoid
Notal Vision Ltd.

Completed

Comparison Between Foresee Home and Optical Coherence Tomography (OCT) Visual Field Defects in Patients With Choroidal Neovascularization (CNV)

Age Related Macular Degeneration

Israel
Notal Vision Ltd.

Completed

Usage of the Home Macular Perimeter (HMP) (HMP)

Age Related Macular Degeneration

Israel
Notal Vision Ltd.

Completed

Usability of the Foresee Home in Intermediate Age Related Macular Degeneration (AMD) Patients (UU2)

Age Related Macular Degeneration

Israel
QLT Inc.

Completed

Safety/Proof of Concept Study of Oral QLT091001 in Subjects With Leber Congenital Amaurosis (LCA) or Retinitis Pigmentosa (RP) Due to Retinal Pigment Epithelial 65 Protein (RPE65) or Lecithin:Retinol Acyltransferase (LRAT) Mutations

LCA (Leber Congenital Amaurosis) | RP (Retinitis Pigmentosa)

United States, Canada, Germany, Netherlands, United Kingdom
Quark Pharmaceuticals

Completed

Safety Study of a Single IVT Injection of QPI-1007 in Chronic Optic Nerve Atrophy and Recent Onset NAION Patients

Optic Atrophy | Non-arteritic Anterior Ischemic Optic Neuropathy

United States, Israel
NLT Spine

Unknown

Prospective Study To Assess The Safety and Efficacy of the PROW LIF Procedure

Degenerative Disc Disease

Israel
Eunice Kennedy Shriver National Institute of Child...
Washington University School of Medicine; University of Oxford; National Human...

Completed

Biomarker Validation for Niemann-Pick Disease, Type C: Safety and Efficacy of N-Acetyl Cysteine

Niemann-Pick Disease, Type C

United States
New England Retina Associates

Completed

Intravitreal Anti-VEGF in Exudative AMD With Epiretinal Membranes

Age Related Macular Degeneration | Epiretinal Membrane
University of British Columbia

Terminated

Trientine Hydrochloride for the Prevention of Macular Edema Associated With Pan-retinal Photocoagulation for Severe Non-proliferative and Proliferative Diabetic Retinopathy

Diabetic Retinopathy

Canada
Nantes University Hospital

Completed

Efficacy and Tolerability of Memantine in Frontotemporal Dementia (FTD) Patients

Dementia

France
The New York Eye & Ear Infirmary

Suspended

Weekly Vaccination With Copaxone as a Potential Therapy for Dry Age-related Macular Degeneration

Dry Age Related Macular Degeneration

United States
New England Retina Associates

Withdrawn

Ranibizumab as a Rescue Therapy for Diabetic Macular Edema

Diabetic Macular Edema

United States
Medical University of Vienna

Completed

Comparison of Reduced Fluence Versus Standard Photodynamic Therapy (in Combination With Intravitreal Triamcinolone Acetate)

Macular Degeneration

Austria
Oraya Therapeutics, Inc.

Unknown

An Open-label Study to Evaluate the Clinical and Economic Benefits of I-Ray in Patients With Choroidal Neovascularization Secondary to Age-related Macular Degeneration (ENDEAVOUR)

Eye Diseases | Age-Related Macular Degeneration | Macular Degeneration | Retinal Diseases | Wet Macular Degeneration

United Kingdom
Allergan

Completed

An Exploratory Study to Evaluate the Safety of Brimonidine Intravitreal Implant in Patients With Retinitis Pigmentosa

Retinitis Pigmentosa

France, United States, Germany, Portugal
Lpath, Inc.
Pfizer

Terminated

iSONEP to Treat Persistent Pigment Epithelial Detachment (PED) in Subjects With Exudative Age-Related Macular Degeneration (AMD) or Polypoidal Choroidal Vasculopathy (PCV) (PED)

Pigment Epithelial Detachment

United States
Allergan

Completed

Retrospective Study in Patients Receiving Two or More OZURDEX® Injections for Retinal Vein Occlusion (RVO)

Macular Edema | Retinal Vein Occlusion

United States
Institut fuer anwendungsorientierte Forschung und...
Novartis Pharmaceuticals; University Medical Center Goettingen

Completed

Efficacy Study of Ranibizumab on Patients With Age-related Macular Degeneration. (RABIMO)

Macular Degeneration

Germany
Columbia University

Terminated

Evoked Retinal Response

Retinitis Pigmentosa

United States
Flexuspine, Inc.

Completed

Fusion Assessment Clinical Trial (FACT)

Degenerative Disc Disease

United States
Novartis

Completed

A 12 Month Core Study to Assess the Efficacy and Safety of Ranibizumab (Intravitreal Injections) in Patients With Visual Impairment Due to Diabetic Macular Edema and a 24 Month Open-label Extension Study (RESTORE)

Diabetic Macular Edema

Greece, Belgium, Spain, France, Netherlands, Australia, Canada, Germany, Hungary, Italy, Switzerland, Turkey, United Kingdom
Medical University of Vienna

Completed

Does Complement Factor H Gene Polymorphism Play a Role in the Regulation of Vascular Tone in the Choroid?

Macular Degeneration | Ocular Physiology | Regional Blood Flow | Genetic Polymorphism

Austria
Medtronic Spinal and Biologics

Completed

INFUSE® Bone Graft/ PEEK Interbody Spacer/ Anterior Cervical Plate Pivotal Clinical Trial (ACDF)

Degenerative Disc Disease

United States
University of Sao Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Intravitreal Bevacizumab and Triamcinolone Associated to Laser Photocoagulation for Diabetic Macular Edema(IBeTA) (IBeTA)

Diabetic Macular Edema

Brazil
Chengdu Kanghong Biotech Co., Ltd.
University of Wisconsin, Madison; Teaching and Research Office of Health Statistics...

Completed

Safety and Efficacy by Multiple Injection of KH902 in Patients With Diabetic Macular Edema (DME) (Frontier-1)

Diabetic Macular Edema

China
University Hospital, Clermont-Ferrand
INSERM CIC 501

Unknown

Efficiency and Safety Study of Pamidronate in Inflammatory Back Pain Due to Degenerative Disk Disease

Back Pain | Low Back Pain | Intervertebral Disc Degeneration | Modic I Discopathy | Magnetic Resonance Imaging (MRI)

France
University of Reading

Completed

Effects of Cocoa Flavanols on Human Cognitive Function

Neural Degeneration

United Kingdom
Interventional Spine, Inc.

Terminated

Percutaneous Dynamic Stabilization (PDS) System Versus Fusion for Treating Degenerative Disc Disease

Lumbar Degenerative Disc Disease

United States
Allergan

Completed

A Retrospective Data Collection Study in Patients Receiving Dexamethasone Intravitreal Implant (Ozurdex®) for Macular Oedema Due to Retinal Vein Occlusion (RVO)

Macular Edema

Germany
Assistance Publique - Hôpitaux de Paris

Completed

Study to Evaluate the Efficacy of Riluzole in Children and Young Adults With Spinal Muscular Atrophy (SMA) (ASIRI)

SMA

France
Retina Institute of Hawaii

Completed

Use of Diagnostic Dye to Identify Areas of Leakeage,in the Retina, Prior to Receiving Focal Laser Treatment

Macular Edema

United States
M.D. Anderson Cancer Center

Completed

Doxil, Gemcitabine, and Velcade (PS341) in Advanced Cancer Patients

Solid Tumors

United States
Retina Institute of Hawaii

Completed

Microcurrent Stimulation to Treat Macular Degeneration

Retinal Diseases | Retinitis Pigmentosa | Stargardt's Disease

United States
Retina Institute of Hawaii

Unknown

Diabetic Macular Edema and Diabetic Retinopathy Screening (TeleMed) With Automated Retinal Photography (DIVER)

Diabetic Macular Edema | Proliferative Diabetic Retinopathy | Severe Nonproliferative Diabetic Retinopathy | Mild Nonproliferative Diabetic Retinopathy | Moderate Nonproliferative Diabetic Retinopathy

United States
Sequenom, Inc.
Center for Eye Research and Education

Completed

Evaluation of the Association Between Genetic Load and Response to Anti-VEGF Therapy in AMD Patients (EVERGREEN)

Age Related Macular Degeneration

United States
Hospital de Clinicas de Porto Alegre

Completed

Safety and Efficacy of Lithium Carbonate in Patients With Spinocerebellar Ataxia Type 3

Spinocerebellar Ataxia Type 3 | Machado Joseph Disease

Brazil
Rudolf Foundation Clinic

Unknown

Impact of Visceral Fat on the Pathogenesis of Age-related Macular Degeneration

Age-related Macular Degeneration

Austria
University of Toronto
Ontario Research Fund

Unknown

Anterior and Posterior Segment Vascular Changes Following Laser and Anti-Vascular Endothelial Growth Factor (VEGF) Treatment of Diabetic Retinopathy (VEGF)

Diabetic Macular Edema

Canada
Assistance Publique - Hôpitaux de Paris

Completed

Evaluation of Birdshot Retine Choroidopathy Treatment by Either Steroid or Interferon alpha2a (BIRDFERON)

Cystoid Macular Edema | Birdshot Chorioretinopathy | Transient Partial Visual Loss

France
Genentech, Inc.

Completed

A Study of Ranibizumab Administered Monthly or on an As-needed Basis in Patients With Subfoveal Neovascular Age-related Macular Degeneration (HARBOR) (HARBOR)

Age-related Macular Degeneration

United States
Vertex Pharmaceuticals Incorporated
Cystic Fibrosis Foundation

Completed

Study of Ivacaftor in Cystic Fibrosis Subjects Aged 12 Years and Older With the G551D Mutation (STRIVE)

Cystic Fibrosis

United States, Canada, Australia, Ireland, France, United Kingdom, Germany, Czech Republic
University of Florida

Completed

Intervertebral Disc Augmentation With Minimally Invasive Surgical Procedure

Degenerative Disc Disease

United States
University of Toronto
Ontario Research Fund

Unknown

Prospective Study Phase: Retinal Oxygen Saturation, Blood Flow, Vascular Function and High Resolution Morphometric Imaging in the Living Human Eye

Glaucoma | Age Related Macular Degeneration | Diabetic Retinopathy.

Canada
Ziv Hospital

Unknown

Comparison of Initial Treatment in With Laser Grid in Diabetic Macular Edema to Intra Vitreal Avastin Injections

Diabetic Macular Edema | Diabetus Mellitus

Israel
University Hospital Schleswig-Holstein
St Thomas; Medical Laser Center Lübeck, Germany

Completed

Selective Retina Therapy (SRT) for Clinically Significant Diabetic Macular Edema

Diabetic Macular Edema
Ludwig-Maximilians - University of Munich

Completed

Dexamethasone-implant for the Treatment of RVO

Macular Edema Caused by Retinal Vein Occlusion

Germany

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