Search clinical trials for: Aldose Reductase Inhibition

Total 3602 results

Eli Lilly and Company

Completed

A Study in People With High Cholesterol

Hypercholesterolemia

United States
Johns Hopkins University
Lupus Research Alliance

Completed

Lupus Atherosclerosis Prevention Study

Systemic Lupus Erythematosus

United States
Buddhist Tzu Chi General Hospital
Pfizer

Unknown

An Open Labeled Pilot Study of Atorvastatin in Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

Taiwan
Radboud University Medical Center
Pfizer; Schering-Plough

Completed

Silent Cerebrovascular Lesion and Cognitive Decline Prevention by Cholesterol Lowering in Elderly AF Patients (SPACE)

Inflammation | Atrial Fibrillation | Magnetic Resonance Imaging | Hemostasis | Neuropsychology

Netherlands
University of California, Davis
Juvenile Diabetes Research Foundation; National Institutes of Health (NIH)

Completed

Monocyte Function and Inflammation in Type 1 Diabetes and Its Modulation

Type 1 Diabetes

United States
Mario Negri Institute for Pharmacological Research

Completed

Ezetimibe and Simvastatin in Dyslipidemia of Diabetes

Type 2 Diabetes

Italy
Abant Izzet Baysal University

Unknown

A Study Evaluating the Effects of Lipid Lowering Treatment on Steroid Synthesis

Diabetes Mellitus | Hypercholesterolemia | Coronary Heart Disease | Non-Coronary Atherosclerotic Disease

Turkey
IRCCS San Raffaele

Completed

Effect of Chronic PDE5-Inhibition on Endothelial Function in Diabetics

Diabetes

Italy
Medical University of Vienna

Completed

Anti-Inflammatory Effect of Statins in the Human Endotoxin Model

Endotoxemia

Austria
Ludwig-Maximilians - University of Munich

Completed

Simvastatin as Inhibitor of Cell Adhesion Mediated Drug Resistance in Patients With Refractory Multiple Myeloma.

Multiple Myeloma
University of Milan

Completed

PDE5-Inhibition With Sildenafil in Chronic Heart Failure

Heart Failure

Italy
Mitsukoshi Health and Welfare Foundation
Daiichi Sankyo Co., Ltd.; Ministry of Health, Labour and Welfare, Japan

Completed

Management of Elevated Cholesterol in the Primary Prevention Group of Adult Japanese(MEGA Study)

Hyperlipidemia
Pfizer

Completed

This Study Uses Ultrasound to Determine Whether Atorvastatin or Pravastatin Effects the Progression of Coronary Plaque.

Coronary Arteriosclerosis

United States
Inotek Pharmaceuticals Corporation

Completed

A Study of INO-1001, an Intravenous PARP (Poly [ADP Ribose] Polymerase) Inhibitor in Acute Heart Attack Patients Undergoing Primary Percutaneous Coronary Intervention

Acute Myocardial Infarction

United States, Israel
Massachusetts General Hospital

Completed

Assessment of the Antiviral Effect of Atorvastatin on Hepatitis C Virus

Hepatitis C

United States
Boston Scientific Corporation

Completed

INTRINSIC RV - Inhibition of Unnecessary RV Pacing With AV Search Hysteresis in ICDs

Tachycardia
University Health Network, Toronto
Abbott Medical Devices; Dr. Douglas Cameron

Completed

Assessment of Prepulse Inhibition for Shock Pain Reduction

Pain Awareness From ICD Shocks

Canada
Institute for the Study of Aging (ISOA)
Pfizer

Completed

Lipitor as a Treatment for Alzheimer's Disease

Alzheimer Disease

United States
Poznan University of Medical Sciences
Yale University

Unknown

Simvastatin and Metformin Therapy in PCOS Women. Prospective Randomised Trial.

Polycystic Ovary Syndrome

Poland
Kos Pharmaceuticals

Completed

The Dose Response of Niacin ER/Lovastatin on Peak Walking Time (PWT) in Patients With Intermittent Claudication - TROPIC

Intermittent Claudication | Peripheral Vascular Disease

United States
Kos Pharmaceuticals

Completed

Effect of Niacin ER/Lovastatin on Peak Walking Time & Claudication Onset Time in Patients With Intermittent Claudication

Intermittent Claudication | Peripheral Vascular Disease
Kos Pharmaceuticals

Completed

Evaluation of the Safety & Efficacy of a Combination of Niacin ER & Simvastatin in Patients With Dyslipidemia (OCEANS)

Hypercholesterolemia
Hospital Britanico

Completed

Inhibition of the Renin Angiotensin System Plus Corticosteroids for the Treatment of Proteinuria in IGA Nephropathy

IGA Nephropathy

Argentina
Kos Pharmaceuticals

Completed

Comparative Efficacy Evaluation of Lipids When Treated With Niaspan & Statin or Other Lipid-Modifying Therapies-COMPELL

Stroke | Diabetes | Atherosclerosis | Dyslipidemia | Coronary Heart Disease
Kos Pharmaceuticals

Completed

Safety & Efficacy of a Combination Niacin ER/Simvastatin in Patients With Dyslipidemia: A Dose-Ranging Study - SEACOAST

Hypercholesterolemia
Hospital Pedro Hispano
Northwestern University

Completed

Rosuvastatin Affecting Aortic Valve Endothelium

Atherosclerosis | Hypercholesterolemia

Portugal
The University of Western Australia

Completed

Regulation of Lipoprotein Metabolism in Obese Men

Obesity | Insulin Resistance | Dyslipidemia

Australia
Angiogenix

Unknown

Efficacy Study of Oral L-Citrulline in Patients Taking Simvastatin With Peripheral Arterial Disease

Peripheral Arterial Disease | Intermittent Claudication

Russian Federation
Bayside Health

Unknown

Atorvastatin in Myeloma

Myeloma

Australia
Amsterdam UMC, location VUmc
Bristol-Myers Squibb; Medical Research Foundation, The Netherlands

Terminated

Anti-Oxidant Therapy In Chronic Renal Insufficiency (ATIC) Study

Chronic Kidney Disease

Netherlands
Technische Universität Dresden

Completed

Comparison of Vascular Effects After Therapy With Irbesartan and Atorvastatin.

Healthy Subjects

Germany
Chestnut Hill Health System

Completed

Statin Therapy Vs. Therapeutic Lifestyle Changes and Supplements

Hyperlipidemia
Poznan University of Medical Sciences
Yale University

Completed

Simvastatin Therapy in Women With Polycystic Ovary Syndrome.

Polycystic Ovary Syndrome

Poland
University Heart Center Freiburg - Bad Krozingen

Completed

Efficacy of Adjusted Clopidogrel Dose in Patients With Insufficient Platelet Inhibition

Coronary Artery Disease | Drug Resistance

Germany
In His Image
Kos Pharmaceuticals

Completed

Efficacy Study of Extended-Release Niacin/Lovastatin Versus Usual Care

Dyslipidemia | Hyperlipidemia | Mixed Hyperlipidemia

United States
Regional Hospital Holstebro

Completed

Effects of Inhibition of NO-Synthesis on Renal Hemodynamics and Sodium Excretion in Patients With Essential Hypertension and Healthy Controls

Hypertension
Regional Hospital Holstebro

Completed

Effects of Systemic NO-Inhibition on Renal Hemodynamics in Patiens With Polycystic Kidney Disease and Chronic Glomerulonephritis

Glomerulonephritis | ADPKD
AZ-VUB
Hoffmann-La Roche

Unknown

First-Line EGFR-1 Tyrosine Kinase Inhibition in Patients With NSCLC With Mutant EGFR Gene

Lung Neoplasms | Non-Small Cell Lung Cancer | Adenocarcinoma, Bronchiolo-Alveolar

Belgium
Kirby Institute
National Heart, Lung, and Blood Institute (NHLBI); The University of New South... and other collaborators

Completed

Pravastatin for Hyperlipidaemia in HIV.

HIV Infections | Cardiovascular Disease | Lipodystrophy | Glucose Metabolism | Lipid Metabolism | Metabolic Abnormality

Australia
University of Ulm
Pfizer

Completed

The Role of Atorvastatin on Monocyte Function in Patients With Coronary Artery Disease and Hypercholesterolemia

Coronary Artery Disease | Hypercholesterolemia | Monocyte Function

Germany
University of Pennsylvania
Merck Sharp & Dohme LLC; The Dana Foundation; Kos Pharmaceuticals

Completed

Carotid Atherosclerosis Regression at Magnetic Resonance Assessment.

Established Carotid Atherosclerosis
Tobinick, Edward Lewis, M.D.

Completed

TNF-Alpha Inhibition for Treatment of Alzheimer's Disease

Alzheimer's Disease

United States
Tobinick, Edward Lewis, M.D.

Completed

TNF-Alpha Inhibition for Treatment of Alzheimer's Disease

Alzheimer's Disease

United States
National Institute of Allergy and Infectious Diseases...

Completed

The Effect of Efavirenz and Nelfinavir on the Blood Levels of Certain Lipid-Lowering Drugs

HIV Infections | Lipodystrophy | HIV Seronegativity

United States
Federal University of São Paulo

Unknown

Simvastatin Effect on End Stage Renal Failure Patients Treated by Peritoneal Dialysis

Peritoneal Dialysis | Renal Failure, End Stage

Brazil
Leiden University Medical Center
The Netherlands Asthma Foundation

Unknown

Towards Restoring the Physiological Inhibition of Airway Narrowing in Asthma

Chronic Obstructive Pulmonary Disease | Asthma

Netherlands
Alabama Neurology Associates, PC
Biogen

Unknown

A Safety Study of Combination Treatment With Avonex and Zocor in Relapsing Remitting Multiple Sclerosis

Relapsing Remitting Multiple Sclerosis

United States
Eunice Kennedy Shriver National Institute of Child...

Unknown

The Effect of 5-Alpha Reductase on Testosterone in Men

Sex Disorders

United States
Eunice Kennedy Shriver National Institute of Child...
National Center for Medical Rehabilitation Research (NCMRR)

Unknown

Electrical Stimulation After Total Knee Arthroplasty

Osteoarthritis | Total Knee Arthroplasty

United States
University of Southern Denmark
Pfizer

Completed

Atorvastatin and Endothelial Function in Type 2 Diabetes Mellitus (ATTEND-Study)

Type 2 Diabetes Mellitus

Denmark

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