Search clinical trials for: small interfering ribonucleic acid (siRNA)

Total 38195 results

French National Agency for Research on AIDS and...
Bristol-Myers Squibb; Gilead Sciences; Triangle Pharmaceuticals; Dupont Applied...

Completed

Once Daily Antiretroviral Therapy in HIV Infected Adults Treated With HAART

HIV Infections
Bavarian Nordic

Completed

Study on Safety, Tolerability and Immunogenicity of an MVA Vaccine Administered to Healthy Subjects

Smallpox

Germany
Gustave Roussy, Cancer Campus, Grand Paris

Unknown

PHASE III TRIAL COMPARING, NEOADJUVANT CHEMOTHERAPY FOLLOWED BY STANDARD RADIOTHERAPY VERSUS THE SAME NEOADJUVANT CHEMOTHERAPY FOLLOWED BY STANDARD RADIOTHERAPY ASSOCIATED WITH DAILY HYDROXYUREA IN THE TREATMENT OF LOCALLY ADVANCED UNDIFFERENTIATED CARCINOMA NASOPHARYNGEAL TYPE.

LOCALLY ADVANCED UNDIFFERENTIATED CARCINOMA NASOPHARYNGEAL TYPE UCNT

France
UMC Utrecht
Utrecht University

Terminated

Effects of Gabapentin in the Treatment of Neuropathic Pain on Driving Performance and Cognition

Chronic Neuropathic Pain

Netherlands
Gustave Roussy, Cancer Campus, Grand Paris

Completed

Comparison of High-Dose Methotrexate (HDM) Plus Doxorubicin to HDM Plus Etoposide-Ifosfamide in Osteosarcoma Children

Osteosarcoma | Localised High Grade Osteosarcoma of the Limbs

France
National Taiwan University Hospital
National Science Council, Taiwan

Unknown

Development of a Comprehensive ADL Scale for Stroke Patients

Cerebrovascular Accidents

Taiwan
National Taiwan University Hospital

Unknown

Can Intravenous Vitamin C Improve Skin Hyperpigmentation in Long-Term Hemodialysis Patients?

Kidney Failure, Chronic

Taiwan
University of Pittsburgh

Completed

Treatment of Geriatric Bipolar Mood Disorders: A Pilot Study

Bipolar Disorder

United States
Kaiser Permanente
National Institute on Aging (NIA); National Center for Complementary and Integrative...

Unknown

Herbal Alternatives for Menopause Symptoms (HALT Study)

Vasomotor Symptoms Associated With Menopause

United States
National Taiwan University Hospital
National Science Council, Taiwan

Unknown

Comparison of Psychometric Properties of Three Depression Measures in Patients With Stroke

Cerebrovascular Accidents

Taiwan
National Taiwan University Hospital
National Science Council, Taiwan

Unknown

Development of a Refined Version of the Stroke Rehabilitation Assessment of Movement Scale for Stroke Patients

Cerebrovascular Accidents

Taiwan
Bayside Health
National Health and Medical Research Council, Australia; Monash University; Cystic...

Unknown

Treatment of Metabolic Alkalosis in Acute Exacerbations of Cystic Fibrosis

Cystic Fibrosis

Australia
Centers for Disease Control and Prevention
US Department of Veterans Affairs

Completed

TBTC Study 25PK: Intensive Pharmacokinetic Study of Three Doses of Rifapentine and 25-Desacetyl Rifapentine

Tuberculosis

United States, Canada
Centers for Disease Control and Prevention
US Department of Veterans Affairs

Completed

TBTC Study 23A: Pharmacokinetics of Intermittent Isoniazid and Rifabutin in HIV-TB

HIV Infections | Tuberculosis

United States, Canada
Menzies School of Health Research
National Health and Medical Research Council, Australia; Wellcome Trust; National...

Completed

To Evaluate Current Efficacy of Antimalarials Used in Timika, Papua, Indonesia

Vivax Malaria | Falciparum Malaria

Indonesia
Heidelberg University

Unknown

Vasoreactivity in Carriers of Genetic Polymorphisms

Healthy

Germany
Centers for Disease Control and Prevention
Kenya Medical Research Institute

Completed

In-Vivo Response of P. Falciparum to Antimalarial Treatment in HIV-Infected and HIV-Uninfected Adults

HIV | Malaria | AIDS

Kenya
Glostrup University Hospital, Copenhagen

Unknown

Hyaluronan Versus NaCl 20 Ml Versus Placebo in Knee Osteoarthritis

Osteoarthritis, Knee

Denmark
Centers for Disease Control and Prevention
US Department of Veterans Affairs

Completed

TBTC Study 22: Efficacy of Once-Weekly Rifapentine and Isoniazid in Treatment of Tuberculosis

Pulmonary Tuberculosis

United States, Canada
West Japan Thoracic Oncology Group

Completed

A Randomized Phase III Trial of Chemotherapy Alone Versus Chemotherapy Followed by Gefitinib in Stage IIIB/IV Non-Small Cell Lung Cancer

Lung Cancer
Titan Pharmaceuticals

Terminated

A Pilot Study of Pivanex in Patients With Chronic Lymphocytic Leukemia

Lymphoma, Small Lymphocytic | Leukemia, Lymphocytic, Chronic

United States
Titan Pharmaceuticals

Completed

Comparative Trial of Pivanex and Docetaxel Vs Docetaxel Monotherapy in Patients With Advanced Non-Small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung

United States, India, United Kingdom
Centers for Disease Control and Prevention
University of Alabama at Birmingham; Universidad del Valle, Guatemala

Completed

Clinical Trial of Rifampin and Azithromycin for the Treatment of River Blindness

Onchocerciasis

Guatemala
Centers for Disease Control and Prevention
Ministry of Health and Population, Malawi

Completed

Prevention of Malaria During Pregnancy Using Intermittent Preventive Treatment With Sulfadoxine-Pyrimethamine: Malawi

HIV Infections | Malaria, Falciparum

Malawi
Wageningen Centre for Food Sciences

Completed

Effect of Betaine, Serine and Folic Acid on Vascular Function in Healthy Volunteers

Cardiovascular Diseases | Healthy

Netherlands
Wageningen Centre for Food Sciences

Completed

Effect of Betaine and Folic Acid on Vascular Function in Healthy Humans

Cardiovascular Diseases | Healthy

Netherlands
French National Agency for Research on AIDS and...
Bristol-Myers Squibb; Gilead Sciences

Terminated

Efficacy and Safety of Tenofovir DF/Atazanavir Enhanced With Low Dose of Ritonavir in HIV-Infected Patients

HIV Infections

France
Pharmasset

Completed

A Study of DPC 817 in HIV-Infected Males

HIV Infections

United States, Germany
National Center for Research Resources (NCRR)
Children's National Research Institute

Completed

A Multicenter Randomized Placebo-Controlled Double-Blind Study to Assess Efficacy and Safety of Glutamine and Creatine Monohydrate in Duchenne Muscular Dystrophy (DMD)

Muscular Dystrophy, Duchenne

United States
Gilead Sciences

Completed

A Study of Adefovir Dipivoxil in HIV-Infected Patients Who Have Not Been Treated With Anti-HIV Drugs

HIV Infections

United States
National Center for Research Resources (NCRR)
National Multiple Sclerosis Society

Completed

Antibiotic Treatment Trial Directed Against Chlamydia Pneumonia in Multiple Sclerosis

Multiple Sclerosis

United States
Immunobiology Research Institute

Completed

Double-Blind Study of Timunox (Thymopentin) in Asymptomatic HIV-Infected Patients Receiving Either Mono (AZT or ddI) or Combination (AZT / ddI or AZT / ddC) Anti-Retroviral Therapy

HIV Infections

United States, Puerto Rico
G D Searle

Completed

Initial Phase II Efficacy and Safety Study of SC-48334 Administered in Combination With Low-Dose Zidovudine (AZT) to Symptomatic HIV-1 Infected Patients With = or > 200 to = or < 500 CD4+ Cells/mm3

HIV Infections

United States
Merck Sharp & Dohme LLC

Completed

Indinavir Plus Efavirenz Plus Adefovir Dipivoxil in HIV-Infected Patients Who Have Not Had Success With Nelfinavir

HIV Infections

United States
Hoffmann-La Roche

Completed

Open Label Ganciclovir Therapy for Sight- or Life-Threatening Cytomegalovirus Disease in the Immunocompromised Patient

HIV Infections | Cytomegalovirus Infections | Cytomegalovirus Retinitis

United States
Palo Alto Medical Foundation

Completed

Toxoplasmic Encephalitis in Patients With AIDS. Treatment and Prevention of Relapse

HIV Infections | Toxoplasmosis, Cerebral

United States
Glaxo Wellcome

Completed

A Study of Zidovudine and T Lymphocyte Transfer in the Treatment of HIV Type III in Patients With AIDS

HIV Infections

United States
National Center for Research Resources (NCRR)
Oregon Health and Science University

Unknown

Phase II Study of Cholesterol- and Cholestanol-Free Diet, Lovastatin, and Chenodeoxycholic Acid for Cerebrotendinous Xanthomatosis

Cerebrotendinous Xanthomatosis

United States
Glaxo Wellcome

Completed

Trial of an Alternative Dosing Regimen of Oral Retrovir in Patients With AIDS or Advanced ARC

HIV Infections

United States, Puerto Rico
Gilead Sciences

Completed

The Safety and Effectiveness of Adefovir Dipivoxil Plus Indinavir Combined With Zidovudine or Lamivudine or Stavudine in HIV-Infected Patients Who Have Not Taken Anti-HIV Drugs

HIV Infections

United States, Puerto Rico
G D Searle

Completed

Phase II Study of the Safety and Surrogate Marker Efficacy of Butyldeoxynojirimycin (SC-48334) and AZT in Symptomatic HIV-1 Infected Patients With 200 - 500 CD4+ Cells/mm3. (NOTE: Asymptomatic HIV-1 Infected Patients Also Eligible)

HIV Infections

United States
University of Southern California

Completed

Prospective Comparison of Ampicillin / Amoxicillin Versus Ceftriaxone for the Treatment of Salmonella Infections in AIDS Patients

HIV Infections | Salmonella Infections

United States
Glaxo Wellcome

Completed

Safety and Effectiveness of Lamivudine When Given Once a Day Versus Twice a Day in Combination With Other Anti-HIV Drugs in HIV-Infected Adults Who Have Never Received Anti-HIV Drugs

HIV Infections

United States, Canada, Argentina, Brazil, Puerto Rico
Hoffmann-La Roche

Completed

A Randomized, Open-Label Study of Alternative Treatment Combinations of Dideoxycytidine (HIVID; ddC) and Zidovudine (AZT) in Patients With HIV Infection

HIV Infections

United States
Glaxo Wellcome

Unknown

Effectiveness and Safety of Epivir/Ziagen/Zerit (3TC/ABC/d4T) Versus Epivir/Ziagen/Sustiva (3TC/ABC/EFV) Versus Epivir/Ziagen/Agenerase/Norvir (3TC/ABC/APV/RTV) in HIV Patients Who Have Never Received Treatment

HIV Infections

United States
Glaxo Wellcome

Completed

An Open-Label Study to Evaluate the Efficacy and Safety of Amprenavir (141W94) and Abacavir Combination Therapy in Protease Inhibitor Experienced Subjects With HIV-1 Infection Who Are Failing Their Current Antiretroviral Treatment Regimen

HIV Infections

United States
Parexel

Completed

The Safety and Effectiveness of Retrovir Plus HIVID Combined With Either Nevirapine or Invirase in the Treatment of HIV Infection

HIV Infections

United States
Astra USA

Completed

A Study of Foscarnet in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS

HIV Infections | Cytomegalovirus Retinitis

United States
Jacobus Pharmaceutical

Completed

Dapsone 100 Mg Versus 50 as Primary Prophylaxis for Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS-Related Complex (ARC)

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
Pharmacia

Completed

A Study of Thymic Humoral Factor (THF Gamma 2) in HIV-Infected Patients

HIV Infections

United States

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