Search clinical trials for: sickle cell disease (SDC)

Total 388317 results

National Center for Research Resources (NCRR)

Unknown

Does Islet Transplantation Eliminate Hypoglycemia?

Diabetes Mellitus
National Center for Research Resources (NCRR)
University of Alabama at Birmingham

Unknown

Phase III Randomized Study of Oral Acyclovir in Infants With Herpes Simplex Virus Infection Involving the Central Nervous System

Herpes Simplex

United States, Canada
Astra USA

Completed

Safety and Efficacy of Intravenous Magnesium Sulfate in Modulating Changes in Symptoms and Divalent Cation Levels Associated With Foscavir Therapy: A Phase IV Randomized, Double-Blind, Placebo-Controlled, Cross-Over, Pilot Study

HIV Infections | Hypocalcemia | Cytomegalovirus Infections

United States
National Center for Research Resources (NCRR)
Ann & Robert H Lurie Children's Hospital of Chicago

Completed

Study of the Relationship Between Calcium Levels and Intact Parathyroid Hormone (iPTH) in Adults With Repaired or Palliated Conotruncal Cardiac Defects

Heart Defects, Congenital | Tetralogy of Fallot | Pulmonary Valve Stenosis | Hypoparathyroidism | Pulmonary Atresia | Conotruncal Cardiac Defects
Fisons

Completed

An Open Label Study to Evaluate the Long-Term Safety and Effectiveness of Aerosol Pentamidine in the Prophylaxis of Pneumocystis Carinii Pneumonia in AIDS Patients

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
Community Research Initiative of New England

Completed

A Study to Evaluate the Effect of Cimetidine on CD4 Lymphocyte Counts in HIV Infection

HIV Infections

United States
Genentech, Inc.

Completed

A Phase I Study of Recombinant Human CD4 Immunoglobulin G (rCD4-lgG) in Patients With HIV-Associated Immune Thrombocytopenic Purpura

HIV Infections | Immune Thrombocytopenic Purpura ( ITP )

United States
National Center for Research Resources (NCRR)
University of Michigan

Completed

Pilot Study of Familial Nonsyndromal Mondini Dysplasia

Mondini Dysplasia

United States
National Institute of Neurological Disorders and...
Massachusetts General Hospital

Unknown

Determinants of Disease Severity in Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis
National Institute of Allergy and Infectious Diseases...
Harvard School of Public Health (HSPH)

Completed

Allopurinol, Glucantime, or Allopurinol/Glucantime for Cutaneous Leishmaniasis in Brazil

Leishmaniasis
Eunice Kennedy Shriver National Institute of Child...

Completed

How Shoes With Rocker Soles Affect Walking

Diabetic Feet

United States
The Institute for Diabetes Discovery, LLC

Unknown

Lidorestat (IDD 676) for the Treatment of Diabetic Neuropathy

Diabetic Polyneuropathy

United States, Canada
Makerere University

Unknown

Mannitol as Adjunct Therapy for Childhood Cerebral Malaria

Cerebral Malaria

Uganda
National Institute of Neurological Disorders and...

Completed

Parkinson's Disease Treatment With Coenzyme Q10

Parkinson's Disease

United States
National Eye Institute (NEI)

Unknown

The Collaborative Longitudinal Evaluation of Keratoconus (CLEK) Study

Keratoconus

United States
Johns Hopkins University

Completed

Pilot Study of Cyclophosphamide in Patients With Life-Threatening Systemic Lupus Erythematosus or Antiphospholipid Antibody Syndrome

Systemic Lupus Erythematosus | Antiphospholipid Antibody Syndrome

United States
Pfizer

Completed

An Open, Multicenter, Randomized, Dose-Ranging Study of Azithromycin in the Treatment of Disseminated Mycobacterium Avium-Intracellulare Complex Infection (MAC) in Patients With Acquired Immune Deficiency Syndrome (AIDS)

HIV Infections | Mycobacterium Avium-Intracellulare Infection

United States
University of Stellenbosch
Stanley Medical Research Institute

Completed

Ethyl-Eicosapentaenoic Acid and Tardive Dyskinesia

Schizophrenia | Dyskinesia

South Africa
Janssen, LP

Completed

An Open Study of the Effect of Itraconazole Oral Solution for the Treatment of Fluconazole Refractory Oropharyngeal Candidiasis in HIV-Positive Subjects.

HIV Infections | Candidiasis, Oral

United States
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Neurodevelopmental and Neurological Study of Infants and Children With HIV-1 Infection and AIDS in Clinical Trials

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
United Biomedical

Completed

A Phase I Safety and Immunogenicity Trial of UBI Microparticulate Monovalent HIV-1 MN Peptide Immunogen in HIV-1 Seronegative Human Subjects

HIV Infections

United States
Pharmacia

Completed

A Double-Blind Randomized Clinical Trial of a Rifabutin Regimen in the Treatment of Mycobacterium-Avium Complex (MAC) Bacteremia in Patients With AIDS

HIV Infections | Mycobacterium Avium-Intracellulare Infection

United States
Lederle Laboratories

Completed

A Randomized, Double-Blind, Placebo Controlled Study of l-Leucovorin in Combination With Trimethoprim / Sulfamethoxazole in the Therapy of Pneumocystis Carinii Pneumonia in Patients With the Acquired Immunodeficiency Syndrome

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
Sandoz

Completed

A Pilot Trial Evaluating an Alternating Schedule of Recombinant Human GM-CSF and Azidothymidine in Patients With HIV Infection and Leukopenia

HIV Infections | Cytopenias

United States
Pharmacia

Completed

Rifabutin Therapy for the Prevention of Mycobacterium Avium Complex (MAC) Bacteremia in AIDS Patients With CD4 Counts = or < 200: A Double-Blind, Placebo-Controlled Trial

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States
Glaxo Wellcome

Completed

A Pilot Study To Evaluate the Effect of Retrovir (Zidovudine: AZT) in the Treatment of Human Immunodeficiency Virus (HIV) Associated Dementia and Neuromuscular Diseases

HIV Infections | Neuromuscular Diseases | AIDS Dementia Complex

United States
Pharmacia

Completed

Rifabutin Therapy for the Prevention of Mycobacterium Avium Complex (MAC) Bacteremia in HIV Positive Patients With CD4 Counts = or < 200: Treatment IND Study

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States
Stanford University

Completed

A Dose-Escalating Study of Ro 31-8959 ( HIV Protease Inhibitor ) in Patients With HIV Disease.

HIV Infections

United States
Gilead Sciences

Completed

A Phase I/II Study of the Safety, Tolerance, and Pharmacokinetics of 9-(2-Phosphonylmethoxyethyl)Adenine ( PMEA; Adefovir ) in Patients With Advanced HIV Disease.

HIV Infections

United States
Sequus Pharmaceuticals

Completed

Use of Stealth Liposomal Doxorubicin HCl ( DOX-SL ) in the Treatment of Moderate to Severe AIDS-Related Kaposi's Sarcoma.

HIV Infections | Sarcoma, Kaposi

United States
Gilead Sciences

Completed

A Study of PMPA in HIV-Infected Patients

HIV Infections

United States
Lexigen Pharmaceuticals

Completed

Phase I Trial of S-1153 in Patients With HIV Infection

HIV Infections

United States
Amgen

Completed

A Study of Granulocyte Colony-Stimulating Factor Plus Recombinant Erythropoietin Plus Zidovudine in Patients With AIDS or AIDS-Related Complex

HIV Infections | Cytopenias

United States
Pfizer

Completed

A Study of Fluconazole in the Prevention of Fungal Infections in HIV-Infected Patients Living in Areas Where Fungal Infections Are Common

HIV Infections | Mycoses | Coccidioidomycosis

United States
Glaxo Wellcome

Completed

The Safety and Effectiveness of 935U83 in HIV-Infected Patients

HIV Infections

United States
Glaxo Wellcome

Completed

A Study to Compare Two Anti-HIV Drug Combinations That Include Amprenavir in HIV-Infected Patients Who Have Failed Anti-HIV Drug Combinations That Did Not Include Amprenavir

HIV Infections

United States
Merck Sharp & Dohme LLC

Completed

The Safety and Effectiveness of MK-639 and Zidovudine, Used Alone and Together, in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs

HIV Infections
National Center for Research Resources (NCRR)
University of California, San Diego

Completed

Evaluation of Fanconi Syndrome and Cystinosis

Fanconi Syndrome | Cystinosis
National Center for Research Resources (NCRR)
Ann & Robert H Lurie Children's Hospital of Chicago

Completed

Phase II Study of Calcitonin for Tumoral Calcinosis

Calcinosis

United States
National Center for Research Resources (NCRR)
Penn State University

Completed

Phase II Pilot Study of Early Cortisol Replacement to Prevent Bronchopulmonary Dysplasia

Bronchopulmonary Dysplasia
National Center for Research Resources (NCRR)

Completed

The Safety and Efficacy of Adjunct Carvedilol in Children With Moderate Heart Failure

Heart Diseases

United States
Romark Laboratories L.C.

Terminated

Safety and Effectiveness of Nitazoxanide for the Treatment of Cryptosporidiosis in AIDS Patients

HIV Infections | Cryptosporidiosis

United States
Agouron Pharmaceuticals

Unknown

Treatment With Nelfinavir or Efavirenz of HIV-Infected Patients Who Have Never Received Anti-HIV Drugs

HIV Infections

United States
Schering-Plough

Completed

Safety and Effectiveness of PEG-Intron in HIV-Infected Patients

HIV Infections

United States, Puerto Rico
National Center for Research Resources (NCRR)
Columbia University

Completed

Study of Low Bone Mass in Premenopausal or Perimenopausal Women

Osteoporosis

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Balloon Valvuloplasty Registry

Heart Diseases | Aortic Valve Stenosis | Mitral Valve Stenosis
SUGEN

Completed

SU5416 in Patients With AIDS-Related Kaposi's Sarcoma Who Have Not Responded to Treatment

HIV Infections | Sarcoma, Kaposi

United States
National Center for Research Resources (NCRR)
Icahn School of Medicine at Mount Sinai

Completed

Genetic Study of Patients and Families With Diaphyseal Medullary Stenosis With Malignant Fibrous Histiocytoma of the Bone

Stenosis | Histiocytoma

United States
National Center for Research Resources (NCRR)

Completed

Popcorn Lung: the Discovery of a New Disease

Lung Diseases, Interstitial | Bronchiolitis Obliterans

United States
Texas Biotechnology Corporation

Completed

Pharmacokinetics/Pharmacodynamics of Argatroban Injection in End-Stage Renal Disease Patients Undergoing Hemodialysis

Kidney Failure, Chronic | Renal Disease, End-Stage

United States

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