Search clinical trials for: Antibodies, Monoclonal

Total 3760 results

National Cancer Institute (NCI)

Completed

Selumetinib and Cetuximab in Treating Patients With Refractory Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific | Recurrent Colon Cancer | Recurrent Rectal Cancer | Stage IVA Colon Cancer | Stage IVA Rectal Cancer | Stage IVB Colon Cancer | Stage IVB Rectal Cancer

United States
GlaxoSmithKline

Completed

Study of Radiolabeled Monoclonal Antibody Anti-B1 for the Treatment of B-Cell Lymphomas and Extended Study to Determine the Safety and Efficacy of Coulter Clone® 131Iodine-B1 Radioimmunotherapy of Advanced Non-Hodgkin's Lymphoma

Lymphoma, Non-Hodgkin
Beth Christian
Gilead Sciences

Completed

Veltuzumab and Milatuzumab in Treating Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma

Lymphoma

United States
National Cancer Institute (NCI)

Terminated

Bevacizumab With or Without MEDI-522 in Treating Patients With Unresectable or Metastatic Kidney Cancer

Renal Cell Carcinoma | Stage III Renal Cell Cancer | Stage IV Renal Cell Cancer | Recurrent Renal Cell Cancer

United States
FibroGen

Completed

Phase 1 Study of FG-3019 in Subjects With Type 1 or Type 2 Diabetes Mellitus and Diabetic Nephropathy

Diabetes Mellitus | Diabetic Nephropathy

United States
AbbVie

Completed

Assessment of the Safety of ABT-308 in Healthy Volunteers and Subjects With Asthma

Asthma
Amgen

Completed

Long-Term Assessment of Safety and Physical Function With AMG 108 in RA

Rheumatoid Arthritis
Novartis Pharmaceuticals

Completed

Phase III Study in Refractory Behcet's Disease (SHIELD)

Behcet Disease

India, Turkey, Spain, Germany, Italy, France, Israel, Greece, Korea, Republic of, Hong Kong, United States, Egypt, Jordan, Singapore, Switzerland, Taiwan, Tunisia
Genentech, Inc.

Completed

A Study of Lebrikizumab in Patients Whose Asthma is Uncontrolled With Inhaled Corticosteroids and A Second Controller Medication (LUTE)

Asthma

United States, Australia
Gruppo Italiano Multiregionale per lo studio dei...
Centro di Riferimento per l'Epidemiologia e la Prev. Oncologica Piemonte

Terminated

Zevalin Twice in Aggressive Non-Hodgkin Lymphoma

Diffuse Large B-Cell Lymphoma

Italy
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...

Active, not recruiting

A Phase 2 Study of Recombinant Anti-IL-17A Humanized Monoclonal Antibody in Chinese Participants With Moderate-to-Severe Plaque Psoriasis

Psoriasis

China
Genentech, Inc.

Completed

A Study to Assess the Safety and Pharmacokinetics of MOXR0916 and Atezolizumab (Also Known as MPDL3280A or Anti-PD-L1) in Participants With Locally Advanced or Metastatic Solid Tumors

Neoplasms

United States, Spain, Belgium, Korea, Republic of, Canada, Australia, France
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Stage I-IIIB Non-Small Cell Lung Cancer After Completion of Radiation Therapy Alone or Combined Radiation Therapy and Chemotherapy

Lung Cancer

United States
Brian Jonas
National Cancer Institute (NCI); Pharmacyclics LLC.

Recruiting

Ibrutinib and Blinatumomab in Treating Patients With Relapsed or Refractory B Acute Lymphoblastic Leukemia

Philadelphia Chromosome Positive | Adult B Acute Lymphoblastic Leukemia

United States
National Cancer Institute (NCI)

Terminated

Monoclonal Antibody Therapy in Treating Patients With Ovarian Epithelial Cancer, Melanoma, Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Non-Small Cell Lung Cancer

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult Acute Myeloid Leukemia With t(8;21)(q22;q22) | Previously Treated Myelodysplastic... and other conditions

United States
Genzyme, a Sanofi Company

Completed

Safety and Efficacy Study of GC1008 to Treat Renal Cell Carcinoma or Malignant Melanoma

Melanoma | Carcinoma, Renal Cell

United States
University of California, San Francisco
Sun Pharmaceutical Industries Limited

Recruiting

Psoriatic Immune Response to Tildrakizumab

Psoriasis Vulgaris

United States
Human Genome Sciences Inc.
GlaxoSmithKline; Emergent BioSolutions

Completed

A Study to Evaluate the Safety and Tolerability of Raxibacumab in Healthy Subjects

Healthy
Genentech, Inc.

Completed

A Study to Evaluate Lebrikizumab (MILR1444A) in Adult Patients With Asthma Who Are Not Taking Inhaled Corticosteroids (MOLLY)

Asthma
Takeda

Withdrawn

Phase 1 Single Subcutaneous Dose Study of MLN1202

Healthy Japanese and Caucasian Male Adults

Japan
AbbVie (prior sponsor, Abbott)

Completed

A Study Comparing the Safety and Efficacy of Two Dosing Regimens of ABT-874 to Placebo in Subjects With Moderate to Severe Chronic Plaque Psoriasis

Plaque Psoriasis

United States, Canada
University of North Carolina, Chapel Hill
AstraZeneca

Not yet recruiting

Anifrolumab for Hidradenitis Suppurativa

Hidradenitis Suppurativa | Hidradenitis | Acne Inversa

United States
Bausch Health Americas, Inc.

Recruiting

An Open-label, Single-dose Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Brodalumab in Pediatric Subjects

Psoriasis

United States
AstraZeneca
Amgen

Completed

Study to Evaluate Tezepelumab in Adults & Adolescents With Severe Uncontrolled Asthma (NAVIGATOR)

Asthma

United States, Austria, Canada, France, Germany, Taiwan, Vietnam, Korea, Republic of, Brazil, Japan, Argentina, Australia, Israel, Russian Federation, Saudi Arabia, South Africa, Ukraine, United Kingdom
AstraZeneca
Amgen

Completed

Tezepelumab Phase 1 PK Study in Healthy Chinese Subjects (DIRECTION-CK)

Healthy Subjects

China
Merck Sharp & Dohme LLC

Completed

A Study of Dalotuzumab (MK-0646) in Breast Cancer Patients (MK-0646-013)

Breast Cancer
Genentech, Inc.

Completed

A Study to Evaluate the Efficacy and Safety of MABT5102A in Patients With Mild to Moderate Alzheimer's Disease (ABBY)

Alzheimer's Disease

United States, Spain, France, Canada, Germany, United Kingdom
Genentech, Inc.

Completed

A Study of Lebrikizumab in Patients With Uncontrolled Asthma Who Are on Inhaled Corticosteroids and A Second Controller Medication (VERSE)

Asthma

United States, Australia
Rambam Health Care Campus
Abbott

Completed

Efficacy of Humira in Behcet Patients With Arthritis

Arthritis; Behcet

Israel
AHS Cancer Control Alberta

Withdrawn

Efficacy and Safety of Treatment With a Single Dose of 90Y-ibritumomab Tiuxetan in Patients With Low Tumor Burden Untreated or Indolent NHL

Lymphoma

Canada
Biotie Therapies Corp.

Completed

BTT1023 in Psoriasis

Plaque Psoriasis

Germany
Jinling Hospital, China

Recruiting

A Study of Multimodal Radiotherapy for Renal Cell Carcinoma Progressed After Prior Immunotherapy

Renal Cell Carcinoma | Radiotherapy | Immune Checkpoint Inhibitor

China
The First Affiliated Hospital with Nanjing Medical...

Not yet recruiting

Evaluation of the Efficacy and Safety of Bevacizumab Combined With PD-1 Monoclonal Antibody in Preoperative Neoadjuvant Therapy for MSS Colorectal Cancer With Liver Metastases

Colorectal Cancer
Shanghai Chest Hospital

Recruiting

Analysis of Drug Resistance in Immune Checkpoint Inhibitors of Non-small Cell Lung Cancer

Non-Small Cell Lung Cancer

China
Ludwig Institute for Cancer Research
National Cancer Institute (NCI)

Completed

Capecitabine and 131I-huA33 in Patients With Metastatic Colorectal Cancer

Colorectal Neoplasms

Australia
Northwestern University
Genentech, Inc.

Completed

Bevacizumab in Pats w/ Recurrent ST Brain Metas Who Have Failed Whole Brain Radiation Therapy

Unspecified Adult Solid Tumor, Protocol Specific | Metastatic Cancer

United States
University of Southern California
National Cancer Institute (NCI)

Terminated

CMP-001 and INCAGN01949 for Patients With Stage IV Pancreatic Cancer and Other Cancers Except Melanoma

Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Adenocarcinoma | Locally Advanced Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm

United States
Shanghai Junshi Bioscience Co., Ltd.

Completed

The Safety and Efficacy of Multiple-dose of JS004 in Subject With HNC

Nasopharyngeal Carcinoma | Head and Neck Squamous Cell Carcinom

China
Abbott

Completed

Effectiveness of Synagis (Palivizumab) Immunoprophylaxis in Preterm Infants With High Risk of Severe Respiratory Syncytial Virus (RSV) Infection (INSPIRA)

Respiratory Syncytial Virus Infection

Peru
AbbVie

Completed

A Study to Evaluate the Bioavailability of Risankizumab Following Subcutaneous Dosing in Healthy Male Participants

Healthy Volunteers

United States
AbbVie

Completed

A Study to Evaluate the Bioavailability of Risankizumab in Pre-filled Syringe or Auto-injector in Healthy Adult Participants

Healthy Volunteers

United States
AbbVie

Completed

Study of Intravenous and Subcutaneous Administration of Risankizumab in Healthy Participants

Healthy Volunteers

United States
Novartis Pharmaceuticals

Completed

Study of Power Doppler Ultrasound (PDUS) to Measure Response of Secukinumab Treatment in Patients With Active Psoriatic Arthritis (PsA) (PDUS)

Psoriatic Arthritis

Germany, Netherlands, Spain, Argentina, Belgium, Colombia, Italy, United States, United Kingdom, Ireland, France, Mexico, Canada, Austria, Czechia, Hungary, Norway
AstraZeneca
Amgen

Completed

Tezepelumab Home Use Study (PATH-HOME)

Asthma

United States, Canada, Poland, Japan
FibroGen

Completed

Safety, Tolerability, and Efficacy Study of Idiopathic Pulmonary Fibrosis (FGCL-3019-049)

Idiopathic Pulmonary Fibrosis

United States
AstraZeneca

Terminated

A Study to Evaluate the Safety of Tralokinumab in Adults and Adolescents With Uncontrolled Asthma

Inadequately Controlled Asthma

Japan
Janssen Research & Development, LLC
GlaxoSmithKline

Completed

A Study of CNTO 136 (Sirukumab), a Human Anti-IL-6 Monoclonal Antibody, Administered Subcutaneously, in Patients With Active Rheumatoid Arthritis Despite Anti-TNF-Alpha Therapy (SIRROUND-T)

Arthritis, Rheumatoid

United States, France, Poland, United Kingdom, Germany, Taiwan, Spain, Mexico, Portugal, Korea, Republic of, Japan, Canada, New Zealand, Russian Federation, Puerto Rico, Austria, Argentina, Lithuania, Belgium, Croatia, Australia, ...
MedImmune LLC

Terminated

A Phase 2, Randomized Dose-ranging Study to Evaluate the Efficacy of Tralokinumab in Adults With Idiopathic Pulmonary Fibrosis

Idiopathic Pulmonary Fibrosis

United States, Australia, Korea, Republic of, Peru, Canada, Israel
Novartis Pharmaceuticals

Terminated

38 Week Extension Study to CAIN457C2303 (SHIELD)

Uveitis

Turkey, Spain, France, Israel, Germany, Greece, Korea, Republic of, Hong Kong, United States, Egypt, Jordan, Singapore, Taiwan, Tunisia
Fundación Pública Andaluza para la gestión de la...

Recruiting

Registry of Patients With Suspected Amyloidosis in Heart Failure (Regamic)

Heart Failure

Spain

Search clinical trials for: Antibodies, Monoclonal

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