Search clinical trials for: Dose-matched Placebo to TS-142

Total 405 results

Haukeland University Hospital
Haraldsplass Deaconess Hospital

Recruiting

N-DOSE AD: A Dose Optimization Trial of Nicotinamide Riboside in Alzheimer's Disease

Dementia | Alzheimer Disease

Norway
Gilead Sciences

Completed

Study Evaluating the Efficacy and Safety of Idelalisib in Combination With Bendamustine and Rituximab for Previously Treated Chronic Lymphocytic Leukemia (CLL) (Tugela ) (Tugela)

Chronic Lymphocytic Leukemia

United States, Hungary, Belgium, United Kingdom, France, Australia, Turkey, Croatia, Italy, Poland, Canada, Greece, Czechia, Ireland, Russian Federation, Spain, Portugal, Romania
University of Maryland, Baltimore

Completed

Salmonella Conjugates CVD 1000: Study of Responses to Vaccination With Trivalent Invasive Salmonella Disease Vaccine

Risk Reduction

United States
Purdue Pharma LP

Completed

Buprenorphine Accumulation and Description of Its Metabolites During Co-Medication of Buprenorphine Transdermal System (BTDS) and Ketoconazole

Healthy

United States
Praxis Precision Medicines

Completed

A Clinical Trial of 2 Doses of PRAX-944 in Participants With Essential Tremor (Essential1)

Essential Tremor

United States, Canada
Aswan University Hospital

Unknown

Aspirin for Prevention of Preeclampsia

Preeclampsia

Egypt
Tesaro, Inc.

Completed

Ph3 Safety/Efficacy Study of Rolapitant for the Prevention of CINV in Subjects Receiving Highly Emetogenic Chemotherapy (HEC)

Chemotherapy-induced Nausea and Vomiting

United States
University of Miami
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effectiveness of Low-Dose Theophylline for the Management of Biomass-Associated COPD

COPD | COPD Exacerbation | Pollution; Exposure | COPD Exacerbation Acute | Pollution Related Respiratory Disorder

Uganda
Tesaro, Inc.

Completed

Ph3 Safety/Efficacy Study of Rolapitant for the Prevention of CINV in Subjects Receiving Highly Emetogenic Chemotherapy

Chemotherapy-induced Nausea and Vomiting

United States
Tesaro, Inc.

Completed

Ph 3 Safety/Efficacy Study of Rolapitant for Prevention of CINV in Subjects Receiving Moderately Emetogenic Chemotherapy

Chemotherapy-induced Nausea and Vomiting

United States
Stanford University

Completed

Study on the Effect of a Beta Blocker on Increased Sensitivity to Pain in Humans Caused by Opioids

Hyperalgesia

United States
Merck Sharp & Dohme LLC

Terminated

A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter Trial to Evaluate the Safety, Tolerability, and Efficacy of MK-8457 in Participants With Rheumatoid Arthritis (MK-8457-010)

Rheumatoid Arthritis
Corcept Therapeutics

Completed

First-in-human Study in Healthy Subjects

Healthy

United Kingdom
Sierra Oncology LLC - a GSK company

Terminated

Gemcitabine and Nab-paclitaxel Combined With Momelotinib in Participants With Previously Untreated Metastatic Pancreatic Ductal Adenocarcinoma

Metastatic Pancreatic Ductal Adenocarcinoma

United States
Merck Sharp & Dohme LLC

Completed

Initial Combination With Pioglitazone Study (0431-064)

Type 2 Diabetes Mellitus
Shiraz University of Medical Sciences

Completed

"Pharmacoepidemiological Evaluation of Autophagy Inhibition in Treatment of HCV Patients Resistant to Standard Therapy. Pilot Study"

Hepatitis C Virus

Iran, Islamic Republic of
University Hospital, Basel, Switzerland

Completed

Acute Dose-dependent Effects of DMT in Healthy Subjects (DMT DR)

Healthy

Switzerland
Gilead Sciences

Terminated

Efficacy and Safety of Simtuzumab (SIM) With FOLFIRI as Second Line Treatment in Colorectal Adenocarcinoma

Colorectal Cancer

Spain, United States, Germany, Italy, Russian Federation, Poland, France
CytoDyn, Inc.

Completed

Study of PRO 140 by Subcutaneous Administration in Adult Subjects With HIV -1 Infection

HIV Infections | HIV -1 Infection

United States
US Department of Veterans Affairs
VA Greater Los Angeles Healthcare System

Withdrawn

A Pilot Study of Deep Brain Stimulation of the Amygdala for Treatment-Refractory Combat Post-Traumatic Stress Disorder (ADIP)

Post Traumatic Stress Disorder

United States
Tehran University of Medical Sciences

Completed

Evaluation of Effects of Silymarin on Cisplatin Induced Nephrotoxicity in Upper Gastrointestinal Adenocarcinoma

Cisplatin Adverse Reaction | Upper GI Cancer

Iran, Islamic Republic of
Novartis Pharmaceuticals

Completed

Proof of Concept Study Evaluating the Efficacy and Safety of MIJ821 in Patients With Treatment-resistant Depression

Depressive Disorder, Treatment-Resistant

Spain, United States
Merck Sharp & Dohme LLC

Completed

Sitagliptin Metformin Add-on Study in Patients With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus (T2DM)
Leonardo Clavijo
Amgen

Unknown

Effect of Evolocumab in Functional Status and LDL Oxidation of Patients With Peripheral Arterial Disease (Evol-PAD)

Peripheral Arterial Disease

United States
Auzone Biological Technology Pty Ltd
TIGERMED AUSTRALIA PTY LIMITED; CMAX Clinical Research Pty Ltd

Completed

A Study of TTYP01 in Healthy Adult Subjects

Healthy Adult Subjects

Australia
Otsuka Pharmaceutical Development & Commercialization...

Completed

Aripiprazole and Lexapro Drug Interaction Study

Healthy

United States
Medical University of Vienna

Completed

Effects of Vitamin C on Hyperoxia-Induced Reduction of Retinal Blood Flow

Ocular Physiology | Regional Blood Flow

Austria
University of Washington
National Institutes of Health (NIH)

Unknown

Modifying Virtual Reality Analgesia With Low-Dose Pain Medication

Virtual Reality Therapy

United States
GlaxoSmithKline

Completed

Pharmacokinetic and Pharmacodynamic (PK and PD) Study of Fluticasone Propionate and Salmeterol Combination Product Delivered in a Capsule-based Inhaler and in a Multi-dose Dry Powder Inhaler in Moderate Asthma Patients and Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) Patients.

Asthma

Australia, New Zealand
Novartis Pharmaceuticals

Completed

A 26-week Treatment Randomized, Double-blind, Double Dummy Study to Assess the Efficacy and Safety of QVA149

Chronic Obstructive Pulmonary Disease

China, Argentina, Taiwan, Chile
CytoDyn, Inc.

Completed

Randomized, Double-Blind, Placebo-Controlled Trial, Followed by Single-Arm Treatment of PRO 140 (PRO140)

HIV

United States, Puerto Rico
Craig Hospital
Allergan; The Craig H. Neilsen Foundation

Completed

Investigating Botulinum Toxin A to Treat Acute Neck/Upper Shoulder Pain Following a New Spinal Cord Injury.

Pain | Spinal Cord Injury

United States
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effect of JNJ-53718678 on the Cardiac Repolarization Interval in Healthy Adult Participants

Healthy

Belgium
University of Texas Southwestern Medical Center
National Center for Research Resources (NCRR)

Completed

Safety and Efficacy of Fluoxetine in Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension

United States
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Childhood Asthma Research and Education (CARE) Network Trial - Montelukast or Azithromycin for Reduction of Inhaled Corticosteroids in Childhood Asthma (MARS) (MARS)

Asthma

United States
The University of Texas Medical Branch, Galveston

Withdrawn

Effect of Lycopene and Isoflavones on Glucose Metabolism

Metabolic Syndrome | Diabetes Mellitus, Non-Insulin-Dependent

United States
AstraZeneca
Bristol-Myers Squibb

Completed

Effects of Single Oral Dose Dapagliflozin QT Study

Healthy

United States
Mutual Pharmaceutical Company, Inc.

Completed

A Pharmacokinetic Study of Colchicine With an Oral Contraceptive

Pharmacokinetics

United States
AO GENERIUM

Withdrawn

Efficacy and Safety of GNR-038 vs Berinert® in Patients With Hereditary Angioedema

Hereditary Angioedema

Russian Federation
University of Surrey
H. Lundbeck A/S

Completed

Study to Investigate the Effects of Melatonin, Temazepam & Zolpidem on Sleep EEG in Men and Women

Insomnia

United Kingdom
Avekshan LLC

Completed

Study for Naltrexone on the Abuse Potential of Methylphenidate

Naltrexone | Methylphenidate Abuse

United States
VA Ann Arbor Healthcare System
University of Michigan

Completed

Ketamine Infusion for Comorbid PTSD and Chronic Pain

PTSD | Chronic Pain

United States
Memorial Sloan Kettering Cancer Center
Bristol-Myers Squibb

Completed

Induction Therapy With Cytarabine, High-Dose Mitoxantrone and Dasatinib for Patients With Philadelphia-Chromosome Positive (Ph+) Acute Lymphoblastic Leukemia

Leukemia | Acute Lymphoblastic Leukemia

United States
Eli Lilly and Company

Terminated

A Study of LY3509754 in Healthy Non-Japanese and Japanese Participants

Healthy

United States
Bristol-Myers Squibb

Completed

A Study to Evaluate the Safety, Tolerability, Drug Levels and Drug Effects of Single and Multiple Doses of BMS-986209 in Healthy Participants

Health Participants

United States
King's College Hospital NHS Trust
King's College London; Fight for Sight (Funder)

Recruiting

Vitrectomy, Subretinal Tissue Plasminogen Activator (TPA) and Intravitreal Gas for Submacular Haemorrhage Secondary to Exudative (Wet) Age-related Macular Degeneration (TIGER). (TIGER)

Eye Diseases | Macular Degeneration, Wet | Sub-Macular Hemorrhage

United Kingdom
The University of Texas Medical Branch, Galveston
National Institute of General Medical Sciences (NIGMS)

Completed

Assessment of Mechanisms of Improved Wound Healing

Burns

United States
Memorial Sloan Kettering Cancer Center
Boehringer Ingelheim; National Comprehensive Cancer Network

Completed

Induction Chemotherapy With Afatinib, Ribavirin, and Weekly Carboplatin/Paclitaxel for Stage IVA/IVB HPV Associated Oropharynx Squamous Cell Cancer (OPSCC)

Head and Neck Cancer | Squamous Cell Cancer

United States
GlaxoSmithKline

Completed

Study Evaluating the 24-Hour Pulmonary Function Profile of Fluticasone Furoate (FF) /GW642444 (Vilanterol) (VI) Inhalation Powder 100/25mcg Once Daily Compared With Fluticasone Propionate/Salmeterol Inhalation Powder 250/50mcg Twice Daily in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

United States, Germany, Ukraine, Spain, South Africa, Italy
Otsuka Pharmaceutical Development & Commercialization...

Completed

Aripiprazole and Effexor XR Drug Interaction Study

Healthy

United States

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