Search clinical trials for: Placebo to Metformin

Total 61832 results

University of Glasgow
Juvenile Diabetes Research Foundation; Maastricht University Medical Center; University... and other collaborators

Completed

REducing With MetfOrmin Vascular Adverse Lesions in Type 1 Diabetes (REMOVAL) (REMOVAL)

Diabetes Mellitus, Type 1

United Kingdom, Netherlands, Australia, Canada, Denmark
University Medical Center Groningen
ZonMw: The Netherlands Organisation for Health Research and Development

Completed

Metformin to Reduce Heart Failure After Myocardial Infarction (GIPS-III)

Coronary Artery Disease | Heart Failure | Diabetes | ST Elevation Myocardial Infarction (STEMI)

Netherlands
University of Massachusetts, Worcester

Completed

Adjunctive Metformin Therapy in Double Diabetes (AMTIDD)

Diabetes Mellitus

United States
Jiangsu HengRui Medicine Co., Ltd.

Unknown

The PK/PD, Efficacy, Safety and Tolerability Study of SHR3824 in Combination With Metformin in Type 2 Diabetes Mellitus Patients

Type 2 Diabetes Mellitus
Cellceutix Corporation

Completed

Efficacy and Safety of Prurisol Administered Orally for Active Mild to Moderate Chronic Plaque Psoriasis

Plaque Psoriasis

United States
University of California, Davis
National Cancer Institute (NCI); Astellas Pharma Inc; Medivation, Inc.

Active, not recruiting

Enzalutamide and Metformin Hydrochloride in Treating Patients With Hormone-Resistant Prostate Cancer

Prostate Cancer

United States
AstraZeneca

Completed

Bioequivalence Study of 500 mg and 1000 mg Glucophage (Metformin) Tablets in Healthy Subjects

Type 2 Diabetes Mellitus

United States
Desentum Oy

Completed

Study to Evaluate Safety, Tolerability and Explorative Efficacy of DM-101PX in Birch Pollen Allergic Participants

Birch Pollen Allergy

Canada
Boehringer Ingelheim

Terminated

A Study to Test How Well Patients With Plaque Psoriasis Tolerate BI 730357 Over a Longer Period and How Effective it is

Psoriasis

United States, Canada, Germany
Gilead Sciences

Completed

Evaluating Ventricular Arrhythmia in Subjects With Implantable Cardioverter Defibrillator or Cardiac Resynchronization Therapy-Defibrillator (TEMPO)

Ventricular Arrhythmia

Netherlands, Israel, United States, Denmark, Canada, Germany, Czechia, Hungary, Poland
Novartis Pharmaceuticals

Completed

Safety and Efficacy of KRP203 in Subacute Cutaneous Lupus Erythematosus

Subacute Cutaneous Lupus Erythematosus

Greece, Germany, Italy
VA Office of Research and Development
Baylor College of Medicine; Michael E. DeBakey VA Medical Center

Recruiting

Diet and Exercise Plus Metformin to Treat Frailty in Obese Seniors (DEMFOS)

Frailty | Aging | Sarcopenic Obesity

United States
Sanofi
Hanmi Pharmaceutical Company Limited

Terminated

Efficacy and Safety of Efpeglenatide Versus Placebo in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin Alone or in Combination With Sulfonylurea (AMPLITUDE-S)

Type 2 Diabetes Mellitus

United States, China, Taiwan
Daiichi Sankyo, Inc.

Terminated

Randomized, Double-blind, Active-controlled, Study of Rivoglitazone in Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

United States
Boehringer Ingelheim

Completed

12 Weeks Treatment With 3 Different Doses of BI 10773 in Type 2 Diabetic Patients

Diabetes Mellitus, Type 2

Argentina, Croatia, Estonia, Germany, Italy, Korea, Republic of, Lithuania, Romania, Russian Federation, Slovakia, Sweden, Taiwan, Ukraine
Merck Sharp & Dohme LLC

Completed

Randomized Sitagliptin Withdrawal Study (MK-0431-845)

Type 2 Diabetes Mellitus
Gilead Sciences

Completed

Study to Evaluate the Safety and Efficacy of Selonsertib, Firsocostat, Cilofexor, and Combinations in Participants With Bridging Fibrosis or Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis (NASH) (ATLAS)

Nonalcoholic Steatohepatitis

Hong Kong, United States, Australia, Puerto Rico, New Zealand, Canada
Ruijin Hospital

Unknown

A Clinical Trial of Metformin in the Maintenance of Non-Hodgkin's Lymphoma Patients

Lymphoma, Large B-Cell, Diffuse | Stage III Follicular Lymphoma

China
University of Pennsylvania

Completed

Effect of Insulin Sensitizer Metformin on AD Biomarkers

Dementia | Vascular Dementia | Alzheimer's Disease | Memory Impairment

United States
Gilead Sciences

Completed

Study to Evaluate the Safety, Tolerability, and Efficacy of Cilofexor in Adults With Primary Sclerosing Cholangitis Without Cirrhosis

Primary Sclerosing Cholangitis

United States, Canada, United Kingdom, Austria
Abbott

Completed

A Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ABT-384 in Elderly Subjects

Healthy

United States
Aswan University Hospital

Unknown

Carbetocin Versus Oxytocin Infusion Plus Tranexamic Acid During Cesarean Section

Cesarean Section Complications

Egypt
AstraZeneca

Active, not recruiting

Efficacy and Safety of Benralizumab in EGPA Compared to Mepolizumab. (MANDARA)

Eosinophilic Granulomatous Vasculitis

United States, Canada, France, Italy, Israel, United Kingdom, Japan, Germany, Belgium
University of Pennsylvania
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National... and other collaborators

Completed

Insulin Resistance and Testosterone in Women

Insulin Resistance | Postmenopause

United States
Dalim BioTech Co., Ltd.

Completed

A Pharmacokinetic Study to Compare Co-administration of Repaglinide and Metformin HCl to Administration of Combination Preparation of Those Two Components

Diabetes Mellitus, Type 2

Korea, Republic of
Meir Medical Center
Clalit Health Services

Unknown

A Double-Blind, Randomized, Active-Comparator (Metformin) Controlled, Clinical Trial to Study the Efficacy and Safety of the Strategy to Start Patients With Type 2 Diabetes Mellitus on Janumet™ Compared to Metformin

Diabetes Type 2

Israel
Hoffmann-La Roche

Active, not recruiting

A Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Ocrelizumab in Adult Participants With Primary Progressive Multiple Sclerosis (FENtrepid)

Multiple Sclerosis, Primary Progressive

United States, Canada, Australia, United Kingdom, Hungary, Bulgaria, Puerto Rico, Poland, Argentina, Brazil, Germany, Greece, Italy, Peru, Portugal, Russian Federation, Spain, Turkey, Ukraine, Israel, France, Switzerland, Colombia, Me... and more
Imperial College London

Not yet recruiting

The GAPSID Study - How GLP-1 Analogues Prevent Steroid-Induced Diabetes

Steroid-Induced Diabetes | Steroid Induced Hyperglycemia

United Kingdom
Eli Lilly and Company

Completed

A Study of LY3556050 in Healthy Participants

Healthy

United States
MedImmune LLC

Completed

Study of MEDI0382 in Combination With Dapagliflozin and Metformin in Overweight/Obese Participants With Type 2 Diabetes

Type 2 Diabetes Mellitus

Hungary, Germany, United Kingdom
Hospital Universitário Clementino Fraga Filho

Completed

Insulin Resistance and Metformin Use on Volume of Benign Thyroid Nodules

Insulin Resistance | Thyroid Nodule

Brazil
Merck Sharp & Dohme LLC

Completed

Effect of SCH 497079 on Metabolic Parameters and Influence of Race/Ethnic Origin on Therapeutic Response (Study P05338)(COMPLETED)

Type 2 Diabetes Mellitus
Dong-A ST Co., Ltd.

Completed

A Study To Evaluate The Safety,Tolerability, PK and PD Of DA-1241 In Healthy Male Subjects

Diabetes Mellitus, Type 2

United States
Bristol-Myers Squibb

Completed

Safety Study of BMS-770767 in Subjects With Type 2 Diabetes

Diabetes Type 2

United States, Canada, Korea, Republic of, Australia
University of Dundee

Completed

Metformin in Insulin Resistant Left Ventricular (LV) Dysfunction (TAYSIDE Trial) (TAYSIDE)

Insulin Resistance | Congestive Heart Failure

United Kingdom
Solvay Pharmaceuticals

Completed

A Randomized, Double-Blind Trial Comparing the Efficacy and Safety of Fenofibrate, Metformin, Their Combination and Placebo in Patients With Metabolic Syndrome.

Patients With Metabolic Syndrome

Hungary, Canada, Finland, Italy, Netherlands, Norway, Poland, Romania, Sweden
University of Alberta
St. Justine's Hospital

Recruiting

A Trial of Metformin in Individuals With Fragile X Syndrome (Met)

Neurobehavioral Manifestations | Genetic Diseases, X-Linked | Mental Retardation, X-Linked | Intellectual Disability | Fragile X Syndrome | Sex Chromosome Disorders | Fragile X Mental Retardation Syndrome | Trinucleotide Repeat Expansion | Fra(X) Syndrome | FXS

Canada
Fujian Akeylink Biotechnology Co., Ltd.

Recruiting

A Randomized, Double-blind, Placebo-controlled Phase IIa Clinical Study to Evaluate the Safety and Efficacy of GST-HG131 Tablets in Patients With Chronic Hepatitis B

Chronic Hepatitis B

China
Shionogi

Completed

Evaluation of S-600918 in Adults With Refractory Chronic Cough

Chronic Cough

United States, United Kingdom, Japan, Ukraine, Poland, Czechia
Desentum Oy

Completed

Study to Evaluate Safety and Tolerability of sc Immunotherapy With DM-101 in Adults With Birch Pollen Allergy

Birch Pollen Allergy

Finland
Gilead Sciences

Terminated

Study to Evaluate the Safety, Tolerability, and Efficacy of Cilofexor in Adults With Primary Biliary Cholangitis Without Cirrhosis (PBC-Phase 2)

Primary Biliary Cholangitis

United States, Canada, Austria, United Kingdom
Mount Sinai Hospital, Canada
Canadian Institutes of Health Research (CIHR)

Completed

Early Intermittent Intensive Insulin Therapy as an Effective Treatment of Type 2 Diabetes (RESET-IT Main Trial) (RESET-IT)

Type 2 Diabetes

Canada
Alyatec

Completed

Validation of Strasbourg Environmental Exposure Chamber ALYATEC in Cat Allergic Subjects With Asthma

Allergy | Allergic Asthma | Allergy to Cats

France
Yonsei University

Completed

Effect of Preoperative Oral Carbohydrates on Quality of Recovery (laparoscopy)

Evidence of Cholecystectomy
Laboratorios Silanes S.A. de C.V.

Suspended

Efficacy and Safety of Metformin Glycinate Compared to Metformin Hydrochloride on the Progression of Type 2 Diabetes (COMETII)

Type 2 Diabetes

Mexico
Merck KGaA, Darmstadt, Germany

Completed

Metformin Extended Release Versus Metformin Immediate Release in Subjects With Type 2 Diabetes (CONSENT)

Diabetes Mellitus, Type 2

Germany
Merck Sharp & Dohme LLC

Completed

A Study of the Effects of Co-Administration of Sitagliptin (MK-0431) and Metformin on Incretin Hormone Concentrations (MK-0431-110)

Type 2 Diabetes Mellitus
Laboratorios Silanes S.A. de C.V.

Completed

Clinical Trial to Evaluate Safety and pK Profile of Metformin Glycinate in Healthy Volunteers (NTC00940472)

Healthy

Spain
Tanta University

Completed

Metformin as Adjuvant Therapy in Obese Knee Osteoarthritis Patients

Knee Osteoarthritis

Egypt
The University of Hong Kong

Not yet recruiting

Metformin to Prevent Preterm Birth in Twin Pregnancy (TwinMet)

Pregnancy Complications | Preterm Birth | Drug Effect | Pregnancy Preterm | Metformin | Twin; Complicating Pregnancy | Premature Obstetric Labor

Search clinical trials for: Placebo to Metformin

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