Clinical Trials Sponsored by Merieux Institute

Total 74303 results

National Eye Institute (NEI)

Completed

Extension Study for the Evaluation of Finasteride in the Treatment of Chronic Central Serous Chorioretinopathy (CSC-Ext)

Retinal Disease

United States
National Cancer Institute (NCI)

Active, not recruiting

Phase 2 Study of Bintrafusp Alfa in Recurrent/Metastatic Olfactory Neuroblastoma (BARON).

Olfactory Neuroblastoma | Esthesioneuroblastoma | Neoplasm of the Nasal Cavity

United States
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Active, not recruiting

The INITIATE Study: Initiating Nicotine Dependence Treatment for Smokers Admitted to Emergency Departments (INITIATE)

Nicotine Dependence, Cigarettes | Nicotine Withdrawal

Canada
Emory University
National Cancer Institute (NCI); National Institutes of Health (NIH)

Completed

Utility of Perfusion MRI to Detect Radiation Necrosis in Patients With Brain Metastases

Metastatic Malignant Neoplasm in the Brain | Invasive Malignant Neoplasm

United States
National Cancer Institute (NCI)

Completed

A Follow-up Study of Women Evaluated and Treated for Infertility

Breast Cancer | Ovarian Cancer | Endometrial Cancer | Thyroid Cancer | Colorectal Cancer, Melanoma

United States
National Eye Institute (NEI)

Completed

Sirolimus to Treat Diabetic Macular Edema (SDME)

Diabetic Retinopathy

United States
National Cancer Institute (NCI)

Active, not recruiting

M7824 Related Adverse Effects in Adults With Cancer

Neoplasms | Skin Neoplasms

United States
National Cancer Institute (NCI)

Suspended

Managing Cancer and Living Meaningfully (CALM) Therapy in Individuals Diagnosed With a Primary Brain Tumor

Depression

United States
Stanford University
National Cancer Institute (NCI); National Institutes of Health (NIH)

Enrolling by invitation

Bone Marrow Grafting for Leukemia and Lymphoma

Lymphoma | Hematologic Diseases | Leukemia

United States
National Cancer Institute (NCI)

Completed

Phase II Trial of LMB-2, Fludarabine and Cyclophosphamide for Adult T-Cell Leukemia

Adult T-Cell Leukemia (ATL)

United States
National Cancer Institute (NCI)

Active, not recruiting

Phase II Trial of Combination Immunotherapy in Subjects With Advanced Small Bowel and Colorectal Cancers

Small Bowel Cancers | Colorectal Cancers

United States
National Cancer Institute (NCI)

Active, not recruiting

Prostate SBRT for Locally Recurrent Prostate Cancer After Prior Radiotherapy

Prostate Cancer | Prostatic Neoplasm

United States
National Cancer Institute (NCI)

Completed

Data Analysis for 04-C-0234 Tenofovir Disoproxil Fumarate Salvage Therapy in HIV-Infected Children and a Study of Its Effect on Bone Metabolism

HIV-Infected Children

United States
National Cancer Institute (NCI)

Active, not recruiting

Study of Baricitinib, a JAK1/2 Inhibitor, in Chronic Graft-Versus-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation

Chronic Graft vs Host Disease | Chronic Graft-Versus-Host Disease

United States
National Cancer Institute (NCI)

Terminated

Intraperitoneal Infusion of Autologous Monocytes With Sylatron (Peginterferon Alfa-2b) and Actimmune (Interferon Gamma-1b) in Women With Recurrent or Refractory Ovarian Cancer, Fallopian Tube Cancer or Primary Peritoneal Cancer

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Cancer

United States
National Cancer Institute (NCI)

Terminated

T-DM1 Alone Versus T-DM1 and Metronomic Temozolomide in Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases Following Stereotactic Radiosurgery

Breast Cancer | Brain Cancer | Brain Metastasis

United States
National Cancer Institute (NCI)

Withdrawn

Omics of Cancer: OncoGenomics

Neoplasms | Cancer

United States
National Cancer Institute (NCI)

Completed

Enzalutamide With or Without Vaccine Therapy for Advanced Prostate Cancer

Prostate Cancer

United States
National Cancer Institute (NCI)

Completed

A Phase I Trial of T Cells Expressing an Anti-GD2 Chimeric Antigen Receptor in Children and Young Adults With GD2+ Solid Tumors

Melanoma | Sarcoma | Osteosarcoma | Neuroblastoma

United States
National Cancer Institute (NCI)

Active, not recruiting

EPOCH and Rituximab to Treat Non-Hodgkin's Lymphoma in Patients With HIV Infection

Lymphoma, Large B-Cell, Diffuse | Lymphoma, AIDS-related

United States
National Cancer Institute (NCI)

Completed

Feasibility and Preliminary Efficacy of a Mindfulness-based Intervention for Children and Young Adults With High Grade or High-Risk Cancer and Their Caregivers

Sarcoma | Leukemia | Astrocytoma | Brain Cancer | Glioblastomas

United States
National Eye Institute (NEI)

Enrolling by invitation

Potential Environmental Causes of Uveal Coloboma

Coloboma

United States
National Cancer Institute (NCI)

Terminated

Oral Decitabine and Tetrahydrouridine as Epigenetic Priming for Pembrolizumab-Mediated Immune Checkpoint Blockade in Patients With Inoperable, or Unresectable Locally Advanced or Metastatic Non-Small Cell Lung Cancers and Esophageal Carcinomas

Carcinoma, Non-Small-Cell Lung | Non-Small Cell Lung Cancer | Lung Cancer | Carcinoma, Esophageal | Malignant Pleural Mesotheliomas

United States
Emory University
National Cancer Institute (NCI); National Institutes of Health (NIH)

Active, not recruiting

Fluciclovine and PSMA PET/CT for the Classification and Improved Staging of Invasive Lobular Breast Cancer

Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Invasive Breast Lobular Carcinoma | Metastatic Breast Lobular Carcinoma

United States
National Cancer Institute (NCI)

Completed

T Cells Expressing a Fully-human AntiCD19 Chimeric Antigen Receptor for Treating B-cell Malignancies

Lymphoma, B-Cell | Lymphoma, Non-hodgkins

United States
National Cancer Institute (NCI)

Completed

Investigation of the Human Immune Response in Normal Subjects and Patients With Disorders of the Immune System and Cancer

B-Cell Lymphoma | Myeloma | T-cell Lymphoma | ATL

United States
Brown University
National Cancer Institute (NCI); National Institutes of Health (NIH)

Completed

Web-based Physical Activity Intervention for Latinas

Inactivity

United States
National Cancer Institute (NCI)

Completed

Chemotherapy Plus Vaccination to Treat Mantle Cell Lymphoma

Mantle Cell Lymphoma | Lymphoma, Mantle Cell

United States
National Cancer Institute (NCI)

Completed

Phase I Study of Recombinant Human IL-15 (rhIL-15) and Mogamulizumab for People With Refractory or Relapsed Adult T-Cell Leukemia and Mycosis Fungoides/Sezary Syndrome

Mycosis Fungoides | Sezary Syndrome | Adult T-Cell Lymphoma/Leukemia

United States
National Cancer Institute (NCI)

Withdrawn

Doxorubicin, CC-(486) (5-azacitidine), Romidepsin, and Duvelisib (hARD) for T-cell Lymphoma

Hepatosplenic T-cell Lymphoma | Enteropathy-Associated T-Cell Lymphoma | Adult T-cell Leukemia/Lymphoma | Extranodal NK-/T-cell Lymphoma, Nasal Type | Monomorphic Epiteliotrophic Intestinal T-cell Lymphoma

United States
National Cancer Institute (NCI)

Completed

Interleukin-15 (IL-5) in Combination With Avelumab (Bavencio) in Relapsed/Refractory Mature T-cell Malignancies

Mycosis Fungoides | Sezary Syndrome | Anaplastic Large Cell Lymphoma | Peripheral T-cell Lymphoma NOS

United States
National Cancer Institute (NCI)

Completed

Ad/HER2/Neu Dendritic Cell Cancer Vaccine Testing

Breast Cancer | Breast Neoplasms | Adenocarcinomas | Metastatic Solid Tumors Characterized by HER2/Neu Expression

United States
National Eye Institute (NEI)

Terminated

Human Samples and Data Repository

Uveitis | Scleritis

United States
National Cancer Institute (NCI)

Completed

Mesothelin-Targeted Immunotoxin LMB-100 in People With Malignant Mesothelioma

Mesothelioma

United States
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Terminated

Ability of L-carnitine to Prevent Heart Damage in Breast Cancer Patients Receiving Anthracycline Chemotherapy

Heart Failure

Canada
National Cancer Institute (NCI)

Terminated

Marizomib for Recurrent Low-Grade and Anaplastic Supratentorial, Infratentorial, and Spinal Cord Ependymoma

Ependymoma | Anaplastic Ependymoma | Ependymomas

United States
National Cancer Institute (NCI)

Terminated

Combining CRLX101, a Nanoparticle Camptothecin, With Enzalutamide in People With Progressive Metastatic Castration Resistant Prostate Cancer Following Prior Enzalutamide Treatment

Prostate Neoplasms | Metastatic Castration Resistant Prostate Cancer

United States
National Cancer Institute (NCI)

Completed

Collection of Saliva and/ or Peripheral Blood From Healthy Volunteers for Research

Healthy Volunteer | Graft vs Host Disease | Graft-Versus-Host Disease

United States
National Cancer Institute (NCI)

Completed

Acceptance and Commitment Training for Adolescents and Young Adults With Neurofibromatosis Type 1, Plexiform Neurofibromas, and Chronic Pain

Neurofibromatosis Type 1 | Plexiform Neurofibromas

United States
National Cancer Institute (NCI)

Completed

Phase I-II Everolimus and Sorafenib in Recurrent High-Grade Gliomas

Glioblastoma | Brain Tumor | Anaplastic Glioma

United States
National Cancer Institute (NCI)

Terminated

Immune Checkpoint Inhibitor M7824 and the Immunocytokine M9241 in Combination With Stereotactic Body Radiation Therapy (SBRT) in Adults With Advanced Pancreas Cancer

Pancreatic Neoplasms | Pancreatic Cancer | Metastatic Pancreatic Cancer | Histologically or Cytologically Confirmed Pancreatic Cancer | Unresectable or Borderline Resectable Pancreatic Cancer

United States
National Cancer Institute (NCI)

Completed

T Cell Receptor Immunotherapy Targeting MAGE-A3 for Patients With Metastatic Cancer Who Are HLA-DP0401 Positive

Melanoma | Cervical Cancer | Breast Cancer | Renal Cancer | Urothelial Cancer

United States
National Cancer Institute (NCI)

Terminated

Multi-Epitope TARP Peptide Autologous Dendritic Cell Vaccination in Men With Stage D0 Prostate Cancer

Prostatic Neoplasms | Prostate Cancer

United States
National Cancer Institute (NCI)

Completed

Mesothelin-Targeted Immunotoxin LMB-100 Alone or in Combination With Nab-Paclitaxel in People With Previously Treated Metastatic and/or Locally Advanced Pancreatic Ductal Adenocarcinoma and Mesothelin Expressing Solid Tumors

Neoplasms | Pancreatic Neoplasms

United States
National Cancer Institute (NCI)

Completed

Campath-1H and EPOCH to Treat Non-Hodgkin's T- and NK-Cell Lymphomas

Lymphoma, T-Cell | Lymphoma, Extranodal NK-T-Cell

United States
National Cancer Institute (NCI)

Terminated

T Cells Expressing Fully-human Anti-CD19 and Anti-CD20 Chimeric Antigen Receptors for Treating B-cell Malignancies and Hodgkin Lymphoma

Lymphoma, B-Cell | Chronic Lymphocytic Leukemia | Lymphoma, Non-hodgkins | B-Cell Chronic Lymphocytic Leukemia

United States
Hospital Universitari Vall d'Hebron Research Institute
Instituto de Salud Carlos III

Completed

Intestinal Dysmotility: Minute Rythm

Motility Disorder of Small Intestine (Disorder)

Spain
National Cancer Institute (NCI)

Completed

A Phase I Study of Quadrivalent Human Papilloma Virus (HPV) (Types 6, 11, 16, 18) Recombinant Vaccine in HIV-Infected and HIV-Negative Pre-Adolescents, Adolescents, and Young Adults

Adolescent | Human Immunodeficiency Virus | Papillomavirus Vaccines | Human Papillomavirus- 6, 11, 16, 18

United States
National Eye Institute (NEI)

Completed

Minocycline to Treat Branch Retinal Vein Occlusion

Retinal Vein Occlusion

United States, United Kingdom
National Cancer Institute (NCI)

Completed

CAR T Cell Receptor Immunotherapy for Patients With B-cell Lymphoma

Primary Mediastinal B-cell Lymphoma | Diffuse, Large B-cell Lymphoma | Diffuse Large B-Cell Lymphoma Transformed From Follicular Lymphoma | Mantle Cell

United States

Clinical Trials Sponsored by Merieux Institute

Sponsors and Collaborators

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