- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT05230121
Intestinal Dysmotility: Minute Rythm
February 7, 2022 updated by: Hospital Universitari Vall d'Hebron Research Institute
Intestinal Dysmotility in Patients With Functional Digestive Symptoms: Significance of Minute Rythm
Introduction: Intestinal manometry may detect phasic pressure patterns that suggest small bowel obstruction.
The most common is the "clustered contractions pattern", characterized by repetitive short spouts of intestinal contractions in the postprandial period.
When encountered in patients with chronic unexplained digestive symptoms, an exhaustive radiological evaluation of the gut should be performed to exclude partial mechanical obstruction.
If no luminal compromise is identified by the imaging studies, an underlying neuropathic disorder of the bowel may be the probable diagnosis.
The objective of this study was to determine the clinical significance of this pattern in patients evaluated for a possible intestinal motility disorder.
Study design: Retrospective analysis of the of patients with minute rhythm pattern detected in intestinal manometric recordings performed between 2010 and 2018 at the Vall d'Hebron Digestive Function Unit in consecutive patients referred for evaluation of intestinal motility due to severe, chronic digestive symptoms and suspected dysmotility.
The manometric recordings that had been informed of minute rhythm pattern, will be retrieved to confirm the original report.
The clinical records of these patients will be reviewed to obtain: a) demographic data, b) digestive symptoms at the time of evaluation, c) history of abdomino-pelvic surgeries or radiotherapy prior to manometry, d) diagnosis of systemic disorders, and e) presence of esophageal, gastric or colonic dysmotility.
Results from radiological and other investigations will be also revised, as well as therapeutic decisions and clinical outcome.
Particularly, whether abdominal imaging studies (simple abdominal X-ray or abdominal CT scans) were performed within 7 days of the manometric study, and whether these studies showed signs of fecal retention (presence of solid stools in the right colon) or not.
Study Overview
Status
Completed
Study Type
Observational
Enrollment (Actual)
62
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
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Barcelona, Spain, 08035
- Hospital Vall d'Hebron
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- ADULT
- OLDER_ADULT
- CHILD
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Sampling Method
Non-Probability Sample
Study Population
Patients with minute rhythm pattern detected in intestinal manometric recordings performed between 2010 and 2018 at the Vall d'Hebron Digestive Function Unit in consecutive patients referred for evaluation of intestinal motility due to severe, chronic digestive symptoms and suspected dysmotility.
Description
Inclusion criteria:
- Patients with minute rhythm pattern by intestinal manometry, defined as short clusters of 3-5 contractions repeating every 1-3 min and occurring over a ≥ 20-cm intestinal segment during a ≥ 30-min period in postprandial conditions.
Exclusion criteria:
- Patients with an incomplete (< 2 hour) postprandial recording.
- Patients with minute rhythm detected exclusively in fasting conditions or lasting less than 30 min in postprandial conditions.
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
fecal retention
Time Frame: 7 days
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Presence of solid stools in the right colon in abdominal imaging studies (simple abdominal X-ray or abdominal CT scans) performed within 7 days of the manometric study
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7 days
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Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Collaborators
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (ACTUAL)
November 30, 2021
Primary Completion (ACTUAL)
January 1, 2022
Study Completion (ACTUAL)
January 10, 2022
Study Registration Dates
First Submitted
January 11, 2022
First Submitted That Met QC Criteria
February 7, 2022
First Posted (ACTUAL)
February 8, 2022
Study Record Updates
Last Update Posted (ACTUAL)
February 8, 2022
Last Update Submitted That Met QC Criteria
February 7, 2022
Last Verified
January 1, 2022
More Information
Terms related to this study
Other Study ID Numbers
- PR(AG)56/2018D
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
NO
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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