Search clinical trials for: FLT3- internal tandem duplication (ITD) mutation

Total 8243 results

Children's Hospital of Soochow University

Recruiting

Safety and Efficacy of Avapritinib in Relapsed or Refractory Pediatric CBF-AML With KIT Mutation

AML, Childhood | C-KIT Mutation | Refractory AML | Relapse/Recurrence | Core Binding Factor Acute Myeloid Leukemia

China
Northwestern University

Recruiting

Surgical Approach to Uterine Septum

Treatment Side Effects | Treatment | Surgical Complication | Uterine Septum | Septum; Uterus

United States
National University of Malaysia

Recruiting

GREM1, HAS2 and PTGS2 Gene Expression Following the in Vitro Maturation (IVM)

in Vitro Maturation | Cumulus Cell | Increased Oocyte Death | GREM1 Gene Mutation

Malaysia
Chengdu New Radiomedicine Technology Co. LTD.

Recruiting

Safety and Efficacy of NRT6003 in Patients With Unresectable Hepatocellular Carcinoma

Unresectable Hepatocellular Carcinoma

China
Maximilian Stahl, MD
Syndax Pharmaceuticals

Not yet recruiting

Revumenib in Combination With 7+3 + Midostaurin in AML

Acute Myeloid Leukemia | Leukemia | AML | AML, Adult | AML With Gene Mutations

United States
Oslo University Hospital

Recruiting

HAI-Floxuridine, or SIRT, Combined With Gemox For Patients With Intra-Hepatic Cholangiocarcinoma Not Amenable to Resection (TOMCAT) (TOMCAT)

Intrahepatic Cholangiocarcinoma | Chemotherapy Effect

Norway
University of Colorado, Denver
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Time and Nutrient-Dependent Effects of Aerobic Exercise on Metabolism in Adults (TANDEM Study) (TANDEM)

Healthy | Overweight and Obesity

United States
China Medical University Hospital

Recruiting

Oxygenation Efficacy of "Intrinseque Health" Non-Rebreathing Mask ("IHNRM")

Respiratory Failure | Respiratory Distress Syndrome | Respiratory Disease

Taiwan
Tenaya Therapeutics
Medical University of South Carolina; Johns Hopkins University; University of... and other collaborators

Recruiting

Non-interventional Study of Seroprevalence of Pre-existing Antibodies Against Adenovirus-associated Virus Vector (AAV9) and the Progression of Disease in Patients With Plakophilin 2 (PKP2)-Associated Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) (RIDGE)

Arrhythmogenic Right Ventricular Cardiomyopathy

United States, Italy, United Kingdom, France, Sweden, Germany
Merck Sharp & Dohme LLC

Recruiting

A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)

Non Small Cell Lung Cancer

United States, Israel, Taiwan, Korea, Republic of, Switzerland, Hong Kong
Al-Razi Hospital

Not yet recruiting

Vastus Intermedius Dry Needling for Knee Stiffness Resulted From Surgically Managed Femoral Fractures With Open Reduction & Internal Fixation.

Femur Fracture
M.D. Anderson Cancer Center
Aadi Bioscience

Not yet recruiting

A Phase I Trial of Combination Gemcitabine and Nab-Sirolimus in Advanced Leiomyosarcomas or Advanced Soft-Tissue Sarcomas With TSC2 or TSC1 Loss-of-function Mutations or Deletions

Leiomyosarcoma | Soft-tissue Sarcomas

United States
University of Southern Denmark

Not yet recruiting

Tissue Therapy of Transsphincteric Anal Fistula (REP-PAF)

Anal Fistula

Denmark
Giulio Frontino

Not yet recruiting

Achieving Rapid, Safe and Sustained Glucose Control in Adolescents With Suboptimally Controlled Type 1 Diabetes Using Advanced Hybrid Closed Loop Systems

Diabetes Mellitus, Type 1
Guangzhou Medical University

Recruiting

Intra-pemetrexed Plus Third-generation Small Molecule TKI Drugs (e.g. 'Osimertinib') Versus Third-generation Small Molecule TKI Drugs Alone for Leptomeningeal Metastasis From Epidermal Growth Factor Receptor Mutation-Positive Non-Small-cell Lung Cancer

Leptomeningeal Metastasis

China
Suzhou Genhouse Bio Co., Ltd.

Recruiting

A Phase Ib/II Clinical Study of GH21 Capsules Combined With Osimertinib Mesylate Tablets in Patients With NSCLC

Non-Small Cell Lung Cancer With EGFR Mutation

China
Radiopharm Theranostics, Ltd

Recruiting

177Lu-anti-PD-L1 sdAb in Metastatic Non-small Cell Lung Cancer

Non Small Cell Lung Cancer | PDL1 Gene Mutation

Australia
Martin Blomberg Jensen

Not yet recruiting

NAPO - Novel Approach for Oligospermia (NAPO)

Infertility, Male

Denmark
Guangdong Provincial People's Hospital

Recruiting

Neoadjuvant Almonertinib Followed by Chemo-immunotherapy in II-IIIB EGFR-mutant NSCLC (NEOVADE)

Non Small Cell Lung Cancer | EGFR Gene Mutation

China
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Recruiting

D-1553 Tablet Versus Docetaxel Injection for KRAS G12C Mutation-positive Locally Advanced or Metastatic Non-small Cell Lung Cancer After Prior Standard Therapy Failure

Non Small Cell Lung Cancer

China
Cairo University

Recruiting

Virtual Reality on Pulmonary Function After Upper Abdominal Surgeries

Respiratory Complication | Abdomen Hernia

Egypt
Pasithea Therapeutics Corp.

Recruiting

PAS-004 in Patients With Advanced Solid Tumors

Advanced Solid Tumors | RAS Mutation | NF1 Mutation | RAF Mutation

United States
Liaoning Tumor Hospital & Institute

Not yet recruiting

Adebrelimab Plus Chemotherapy as Neoadjuvant Therapy in Resectable NSCLC Harboring Driver Gene Mutations

Non Small Cell Lung Cancer
Guangzhou Medical University

Not yet recruiting

Intrathecal Pemetrexed for Leptomeningeal Metastasis From Lung Adenocarcinoma That Progressed After Osimertinib.

Leptomeningeal Metastasis
Dizal Pharmaceuticals

Recruiting

A Phase II Clinical Trial of DZD9008 in Combination With AZD4205 in Standard Treatment Failed NSCLC Patients With EGFR Mutations (WU-KONG21)

Non-small Cell Lung Cancer

China
Oregon Social Learning Center
Office of Planning, Research & Evaluation

Recruiting

KEEP Connecting Kin (KEEP-CK)

Parenting | Externalizing Behavior | Parent Stress | Internalizing Behavior | Child Permanency | Service Utilization

United States
Marshall University
Arthrex, Inc.

Recruiting

Return to Play After ACL Reconstruction With Bone Marrow Aspirate, DBM, and an Internal Brace

Anterior Cruciate Ligament Rupture

United States
Hellenic Institute for the Study of Sepsis

Recruiting

Clarithromycin Treatment to Prevent Sepsis Progression in CAP (REACT) (REACT)

Community-acquired Pneumonia

Greece
ViGeneron GmbH

Recruiting

Safety and Tolerability of Intravitreal Administration of VG901 in Patients With Retinitis Pigmentosa Due to Mutations in the CNGA1 Gene

Retinitis Pigmentosa

Germany
National Taiwan University Hospital

Recruiting

Applying Mobile Healthcare Education to Improve Cutaneous Self-care Capability

Cancer | Drug-Related Side Effects and Adverse Reactions | Cancer, Treatment-Related | EGFR Gene Mutation

Taiwan
University of Chicago

Not yet recruiting

Ivosidenib and Ruxolitinib in Patients With Advanced Myeloproliferative Neoplasms (MPNs) That Have an IDH1 Gene Mutation (MPN)

Myeloproliferative Neoplasms

United States
Central Clinical Hospital of the Ministry of Internal...

Not yet recruiting

Erector Spinae Plane (ESP) Block vs Intravenous Lignocaine Infusion in (VATS)

Thoracic Surgery, Video-Assisted

Poland
Eli Lilly and Company

Recruiting

A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a)

Elevated Lp(a) | Atherosclerotic Cardiovascular Disease (ASCVD)

United States, Australia, Spain, Canada, Argentina, China, Italy, France, Japan, Taiwan, Korea, Republic of, Denmark, Germany, Hungary, Israel, Austria, Belgium, Netherlands, Brazil, Mexico, Romania, United Kingdom, Greece, Czechia, Poland and more
NYU Langone Health

Recruiting

Internal Bracing Following ACL Reconstruction

ACL Injury

United States
Deciphera Pharmaceuticals LLC

Recruiting

Study of DCC-3084 in Participants With Advanced Malignancies Driven by the Mitogen-Activated Protein Kinase (MAPK) Pathway

Melanoma | Non-Small Cell Lung Cancer | Advanced Solid Tumor | Pancreatic Ductal Adenocarcinoma | BRAF Gene Mutation | RAS Mutation | NF1 Mutation | RAF Mutation | CRAF Gene Mutation

United States
University of Bern
University of Zurich; University of Bristol; ETH Zurich; University of KwaZulu

Recruiting

HIV-1 Subtype-specific Drug Resistance in Patients Failing Dolutegravir (DTG) Based Regimen (DTG-Resist)

Hiv

Mexico, Malawi, Argentina, Brazil, Burkina Faso, Cambodia, Cameroon, Congo, Côte D'Ivoire, Kenya, Rwanda, Tanzania, Thailand, Uganda, Zambia, Zimbabwe
Hospices Civils de Lyon

Not yet recruiting

Oxalate Excretion Profile in Patients With a Heterozygous Mutation of the AGXT (Alanine-glyoxylate Aminotransferase) Gene (HETEROX)

Hyperoxaluria (Disorder)

France
Alireza Shamshirsaz

Not yet recruiting

Fetal Endotracheal Occlusion (FETO) in Fetuses With Severe Congenital Diaphragmatic Hernia

Congenital Diaphragmatic Hernia

United States
Jazz Pharmaceuticals

Recruiting

Efficacy and Safety of Zanidatamab With Standard-of-care Therapy Against Standard-of-care Therapy for Advanced HER2-positive Biliary Tract Cancer

Biliary Tract Cancer | HER2 Gene Mutation

United States, Puerto Rico
Phramongkutklao College of Medicine and Hospital

Recruiting

Effect of Silymarin Against Methotrexate-induced Liver Injury in Rheumatic Diseases

Rheumatoid Arthritis | Psoriasis | Psoriatic Arthritis

Thailand
Peking University Third Hospital
Beijing Yanqing Hospital

Recruiting

A Prospective Multicenter Cohort Study About Internal Fixation Using PFUN Versus PFNA for Femoral Intertrochanteric Fracture

Femoral Intertrochanteric Fractures

China
Institut National de la Santé Et de la Recherche...

Recruiting

X-linked Moesin Associated Immunodeficiency (X-MAIDReg)

Infections | Autoimmune Diseases | Diagnosis | Immune Deficiency

France, United States, Australia, Belgium, Japan, Netherlands
University of Bonn

Recruiting

Investigation of the Influence of the Human Microbiome on Giant Cell Arteritis (GCA-Biom)

Giant Cell Arteritis

Germany
The Affiliated Hospital of Xuzhou Medical University

Recruiting

Effect of Mutations in T2DM Susceptibility Genes on the Expression of Susceptibility Genes in Patients With T2DM and Controls

Type 2 Diabetes Mellitus | Genetic Mutations | Gene Polymorphisms | Susceptibility, Genetic

China
Chengdu New Radiomedicine Technology Co. LTD.

Not yet recruiting

Safety and Efficacy of NRT6008 in Patients With Unresectable Locally Advanced Pancreatic Cancer (LAPC)

Unresectable Pancreatic Cancer

China
Baylor College of Medicine
Doris Duke Charitable Foundation

Recruiting

Clinical and Molecular Biomarker Studies in RAI1 (Retinoic Acid-Induced 1) -Related Disorders

RAI1 Gene 17P11.2 Deletion+Duplication

United States
Implicit Bioscience

Recruiting

IC14 (Atibuclimab) in Arrhythmogenic Cardiomyopathy

Arrhythmogenic Right Ventricular Dysplasia | Arrhythmogenic Right Ventricular Cardiomyopathy 1 | Arrhythmogenic Left Ventricular Cardiomyopathy | Arrhythmogenic Cardiomyopathy

United States
Dizal Pharmaceuticals

Recruiting

DZD9008 In Combination With Bevacizumab in Locally Advanced or Metastatic NSCLC Patients With EGFR Mutation (WU-KONG29)

Non-small Cell Lung Cancer

China
Yonsei University

Not yet recruiting

Effect of Alfacalcidol on Muscle Function in Osteoporosis Patients

Sarcopenia

Korea, Republic of
Tandem Diabetes Care, Inc.
Jaeb Center for Health Research

Recruiting

Investigational Extended Wear Insulin Infusion Set in People With Type 1 Diabetes

Type1diabetes

United States

Search clinical trials for: FLT3- internal tandem duplication (ITD) mutation

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