Search clinical trials for: Moderate to severe sensorimotor diabetic polyneuropathy

Total 477384 results

InSightec

Recruiting

A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Pallidotomy for the Treatment of Advanced, Idiopathic Parkinson's Disease With Medication-refractory Moderate to Severe Motor Complications

Movement Disorders | Parkinsons Disease | Neurology

United States, Japan
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...

Recruiting

A Phase 3 Study of Recombinant Anti-IL-17A Humanized Monoclonal Antibody in Chinese Participants With Moderate-to-Severe Plaque Psoriasis

Psoriasis

China
First Affiliated Hospital Xi'an Jiaotong University
Nanjing First Hospital, Nanjing Medical University; Beijing Tongren Hospital; People's Hospital of Xinjiang Uygur Autonomous Region and other collaborators

Not yet recruiting

Rapamycin Plus Methylprednisolone Versus Methylprednisolone Alone in Active, Moderate-to-severe Graves' Orbitopathy.

Graves Ophthalmopathy

China
Huabo Biopharm Co., Ltd.

Not yet recruiting

A Study to Evaluate the Efficacy and Safety of HB0017 in Patients With Moderate to Severe Plaque Psoriasis

Plaque Psoriasis

China
Parnassia Addiction Research Centre
Radboud University Medical Center; Columbia University; Academisch Medisch Centrum... and other collaborators

Not yet recruiting

Efficacy and Safety of Sustained-release Dexamphetamine in Patients With Moderate to Severe Cocaine Use Disorder

Cocaine Use Disorder
E-nitiate Biopharmaceuticals (Hangzhou) Co., Ltd.

Not yet recruiting

A Study of QY201 Tablet in Subjects With Moderate to Severe Atopic Dermatitis

Atopic Dermatitis
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Recruiting

A Phase III Study of Jaktinib in Adults With Moderate and Severe Atopic Dermatitis

Atopic Dermatitis

China
University of Aarhus
Aarhus University Hospital; Sygehus Lillebaelt

Recruiting

Internet-based Treatment for Patients Suffering From Severe Functional Somatic Disorders (OneSTEP)

Irritable Bowel Syndrome | Fibromyalgia | Chronic Fatigue Syndrome | Bodily Distress Disorder Moderate | Bodily Distress Disorder Severe | Somatization

Denmark
Instituto Mexicano del Seguro Social
Instituto Nacional de Salud Publica, Mexico; Universidad Nacional Autonoma... and other collaborators

Recruiting

Effect of Electroacupuncture on Sensitive Symptoms of Distal Diabetic Peripheral Neuropathy (EA&DPN)

Diabetic Peripheral Neuropathic Pain | Diabetic Peripheral Neuropathy | Acupuncture | Diabetic Polyneuropathy | Electroacupuncture | Nerve Conduction

Mexico
Spine BioPharma, Inc
MCRA

Recruiting

Moderate - Severe Degenerative Disc Disease Evaluation of the Lumbar Spine (MODEL)

Lumbar Degenerative Disc Disease

United States
Pharmbio Korea Co., Ltd.

Recruiting

Study of PBK_L1704 for the Treatment of Moderate to Severe Acute Pain After Bunionectomy in South Korea

Acute Pain

Korea, Republic of
Q32 Bio Inc.

Recruiting

Evaluating Safety and Efficacy of ADX-914 in Patients With Moderate to Severe Atopic Dermatitis (SIGNAL-AD)

Atopic Dermatitis

United States
Pan Xiangbin

Not yet recruiting

To Evaluate the Efficacy and Safety of the Transfemoral Mitral Valve Repair System in the Treatment of Patients With Moderately Severe and Severe Functional Mitral Regurgitation(FMR) Who Remained Clinically Symptomatic After Guideline-directed Medical Treatment

Mitral Valve Insufficiency

China
The Hospital for Sick Children

Recruiting

A Mindfulness-Based Intervention to Improve CPAP

Obstructive Sleep Apnea | Obstructive Sleep Apnea (Moderate to Severe)

Canada
Teva Branded Pharmaceutical Products R&D, Inc.

Recruiting

A Study to Test the Effect of TEV-48574 in Moderate to Severe Ulcerative Colitis or Crohn's Disease (RELIEVE UCCD)

Crohn Disease | Colitis, Ulcerative

United States, Bulgaria, Czechia, Hungary, Poland, Spain, Belgium, France, Italy, Japan, Norway, Slovakia, Germany, Canada, Ukraine, United Kingdom, Israel, Serbia
Celltrion

Recruiting

To Compare Pharmacokinetics, Efficacy, and Safety of CT-P17 With Humira in Patients With Moderate to Severe Chronic Plaque Psoriasis

Moderate to Severe Chronic Plaque Psoriasis

Estonia
AbbVie

Recruiting

An Observational Study to Assess Change in Disease Activity and Adverse Events of Upadacitinib in Adult Participants With Moderate to Severe Ulcerative Colitis (UC) in Real-World Practice (PROFUNDUS)

Ulcerative Colitis

Germany, Russian Federation, United Arab Emirates, United Kingdom, Australia, Ireland, Argentina, Canada, Kuwait, Israel, Portugal, Czechia, France, Greece, Italy, Spain
Sanofi

Recruiting

Long-Term Safety and Efficacy Evaluation of Amlitelimab in Participants of Previous Amlitelimab Moderate to Severe Atopic Dermatitis Clinical Trials (RIVER-AD)

Dermatitis Atopic

Canada, United States, Australia, Bulgaria, Czechia, Germany, Hungary, Japan, Poland, Spain, Taiwan, United Kingdom
Ganzhou Hemay Pharmaceutical Co., Ltd

Recruiting

Phase II Study of Hemay005 in Patients With Active Ulcerative Colitis

Moderate to Severe Ulcerative Colitis

China
Evolus, Inc.
Avania

Recruiting

Non Interventional Safety Study of NUCEIVA for the Treatment of Moderate-to-Severe Glabellar Lines

Glabellar Frown Lines

Germany
Diskapi Teaching and Research Hospital

Recruiting

Transcutaneous Pulsed Radiofrequency in Diabetic Polyneuropathy

Neuropathy;Peripheral

Turkey
Bristol-Myers Squibb

Recruiting

A Study to Evaluate the Efficacy, Safety, and Drug Levels of Oral Ozanimod in Pediatric Participants With Moderately to Severely Active Crohn's Disease With an Inadequate Response to Conventional Therapy

Crohn Disease

United States, Belgium, Hungary, France, Canada, Spain, Australia, Germany, Poland, United Kingdom
Changhai Hospital
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University and other collaborators

Not yet recruiting

Magnetically Controlled Capsule Endoscope System in Stomach Examination of Moderately and Severely Obese Patients

Obesity

China
Janssen Research & Development, LLC

Recruiting

A Study of Aticaprant as Adjunctive Therapy in Adult Participants With Major Depressive Disorder (MDD) With Moderate-to-severe Anhedonia and Inadequate Response to Current Antidepressant Therapy (VENTURA-1)

Anhedonia | Depressive Disorder, Major

United States, Spain, Bulgaria, Italy, Poland, Belgium, Argentina, Czechia, Hungary, Sweden, Brazil, Australia, Portugal
Shereen Saad Eldin Mohamed Ali

Recruiting

Correlation of HbA1c With Electrophysiological Studies and Gait Performance in Diabetic Polyneuropathy Patients

Diabetic Polyneuropathy

Egypt
Central Hospital, Nancy, France

Recruiting

A Study to Evaluate Biomarkers in Moderate to Severe Ulcerative Colitis (UC) Patients Treated With Different Targeted Therapies (ImmUniverse)

Inflammatory Bowel Diseases | Ulcerative Colitis

France
AbbVie

Recruiting

A Study to Assess Change in Disease Activity in Adolescents and Adults With Moderate to Severe Prurigo-type Atopic Dermatitis in Japan Who Are Treated With Oral Upadacitinib (ADMIRE)

Atopic Dermatitis

Japan
Frontier Biotechnologies Inc.

Recruiting

Evaluate the Efficacy and Safety of FB2001 in Hospitalized Patients With Moderate to Severe COVID-19 (BRIGHT Study)

COVID-19

China
PhytoHealth Corporation

Recruiting

PG2 Injection for the Treatment of moderate-to Severe Fatigue in Breast Cancer Patients

Cancer-related Fatigue

Taiwan
First Affiliated Hospital Xi'an Jiaotong University

Not yet recruiting

Efficacy and Safety of Memantine and Sodium Oligomannate in Patients With Moderate to Severe Alzheimer's Disease

Alzheimer Disease | Efficacy | Treatment | Safety
Takeda

Recruiting

A Study of Vedolizumab SC Given to Adults With Moderate to Severe Ulcerative Colitis or Crohn's Disease in South Korea

Crohn's Disease | Ulcerative Colitis | Inflammatory Bowel Disease (IBD)

Korea, Republic of
Suzhou Alphamab Co., Ltd.

Recruiting

KN057 Multiple Dose Study in Moderately Severe to Severe Hemophilia

Hemophilia

China
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Up-front Matched Unrelated Donor Transplantation in Pediatric Patients With Idiopathic Aplastic Anemia (UPFRONT-MUD)

Severe Aplastic Anemia | Idiopathic Aplastic Anemia | Moderate Aplastic Anemia Requiring Transfusions
Nadja Naenni

Recruiting

The Adjunctive Effect of Soft Tissue Augmentation Procedures of Moderate-severe Peri-implantitis

Peri-Implantitis

Germany, Singapore, Switzerland
Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Not yet recruiting

Efficacy and Safety of SHR-1314 by Subcutaneous Injection in Active Moderate to Severe Graves' Orbitopathy Patients

Active Moderate to Severe Graves' Orbitopathy
AbbVie

Recruiting

An Observational Study of Upadacitinib to Assess Change in Disease Activity in Canadian Adult Participants With Moderate-to-Severe Atopic Dermatitis Who Are Inadequate Responders To or Discontinuing Dupilumab (CAN UpTIMISE)

Atopic Dermatitis

Canada
Vitti Labs, LLC

Recruiting

Safety and Effectiveness of Placental Derived Exosomes and Umbilical Cord Mesenchymal Stem Cells in Moderate to Severe Acute Respiratory Distress Syndrome (ARDS) Associated With the Novel Corona Virus Infection (COVID-19)

Respiratory Distress Syndrome | COVID-19 Acute Respiratory Distress Syndrome

United States
Innovent Biologics (Suzhou) Co. Ltd.

Recruiting

A Study to Evaluate IBI112 in the Treatment of Moderate to Severe Active Ulcerative Colitis

Ulcerative Colitis (UC)

China
Bristol-Myers Squibb

Recruiting

An Open-label Study of Ozanimod in Moderate to Severe Ulcerative Colitis in Clinical Practice

Colitis, Ulcerative

United States, United Kingdom
LEO Pharma

Recruiting

Efficacy and Safety of Delgocitinib Cream in Adolescents 12-17 Years of Age With Moderate to Severe Chronic Hand Eczema (DELTA TEEN)

Chronic Hand Eczema

Spain, France, Belgium, Australia, Canada, Poland, United Kingdom
Charite University, Berlin, Germany

Recruiting

Atopy Network - Comprehensive Allergy Centers: Medical Care of Patients With Moderate to Severe Allergic Diseases (ATAC)

Atopic Disorders

Germany
NEMA Research, Inc.

Recruiting

Ketorolac Applied by Continuous IV Infusion for Treatment of Moderately Severe Postoperative Pain Following Bunionectomy

Pain, Postoperative

United States
RemeGen Co., Ltd.

Recruiting

A Study of Telitacicept for the Treatment of Moderately to Severely Active Systemic Lupus Erythematosus (REMESLE-1)

Systemic Lupus Erythematosus

United States, Colombia, Bulgaria, Poland, Puerto Rico, Argentina, Australia, Chile, Hungary, Spain, Germany, Philippines
Natalie Kreitzer
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

Caregiver Wellness After Traumatic Brain Injury (CG-WELL): An Intervention Designed to Promote Well-being in Caregivers of Acute Moderate to Severe Traumatic Brain Injuries (CG-Well)

Trauma, Brain

United States
Samsung Pharmaceutical Co., Ltd.

Not yet recruiting

GV1001 Subcutaneous for the Treatment of Moderate to Severe Alzheimer's Disease(AD)

Moderate to Severe Alzheimer's Disease
Fundación Pública Andaluza para la gestión de la...

Recruiting

Pupillometry Techniques Usage to Quantify the Programming Parameters Effect in the Auditory Effort in Zti Opticon Cochlear Implant Adult Users

Bilateral Sensorineural Hearing Loss | Unilateral Sensorineural Hearing Loss

Spain
Genmab
AbbVie

Recruiting

A Study to Evaluate Adverse Events and Change in Disease Activity of Subcutaneous (SC) Epcoritamab in Combination With Oral and Intravenous Anti-Neoplastic Agents in Adult Participants With Non-Hodgkin Lymphoma

Non-Hodgkin Lymphoma

United States, France, Israel, Korea, Republic of, Spain, Taiwan, Netherlands, Czechia, Japan, Hungary, Germany, Denmark
McMaster University

Recruiting

Tezepelumab on Airway Structure and Function in Patients With Uncontrolled Moderate-to-severe Asthma

Asthma

Canada
UCB Biopharma SRL

Recruiting

A Single-ascending Dose (Part A) and Repeat-dose (Part B) Study to Investigate the Safety, Pharmacokinetics and Efficacy (Part B Only) of UCB1381 in Healthy Study Participants (Part A) and in Study Participants With Moderate to Severe Atopic Dermatitis (Part B)

Atopic Dermatitis

United States
Keymed Biosciences Co.Ltd

Recruiting

A Study of CM310 in Patients With Moderate-to-Severe Atopic Dermatitis

Atopic Dermatitis

China

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