Search clinical trials for: Multicenter Randomized Study

Total 127392 results

National Center for Research Resources (NCRR)
Children's National Research Institute

Completed

A Multicenter Randomized Placebo-Controlled Double-Blind Study to Assess Efficacy and Safety of Glutamine and Creatine Monohydrate in Duchenne Muscular Dystrophy (DMD)

Muscular Dystrophy, Duchenne

United States
Shaman Pharmaceuticals

Completed

A Double-Blind, Randomized, Placebo-Controlled, Multicenter Study to Assess the Efficacy and Safety of Orally Administered SP-303 for the Treatment of Diarrhea in Acquired Immunodeficiency Syndrome (AIDS) Patients

HIV Infections | Diarrhea

United States, Puerto Rico
Hoffmann-La Roche

Completed

A Randomized, Parallel Arm, Comparative, Open Label, Multicenter Study of the Activity and Safety of Two Formulations of Saquinavir in Combination With Other Antiretroviral Drugs

HIV Infections

Canada, United States
Merck Sharp & Dohme LLC

Completed

A Multicenter, Open-Label, Randomized, 24-Week Study to Compare the Safety and Activity of Indinavir Sulfate, 800 Mg q 8 h Versus 1,200 Mg q 12 h in Combination With Zidovudine and 3TC

HIV Infections

United States
Pfizer

Completed

An Open, Multicenter, Randomized, Dose-Ranging Study of Azithromycin in the Treatment of Disseminated Mycobacterium Avium-Intracellulare Complex Infection (MAC) in Patients With Acquired Immune Deficiency Syndrome (AIDS)

HIV Infections | Mycobacterium Avium-Intracellulare Infection

United States
Otsuka Pharmaceutical Development & Commercialization...

Completed

Multicenter, Randomized, Double-Blind, Placebo Controlled, Efficacy Study on the Effects of Tolvaptan on Left Ventricular Dilatation in Congestive Heart Failure Patients

Congestive Heart Failure

Canada, United States
Glaxo Wellcome

Completed

A Phase III Randomized Double-Blind, Multicenter Study to Evaluate the Safety and Efficacy of 3TC/ZDV/1592U89 and 3TC/ZDV/IDV in HIV-1 Infected Antiretroviral Therapy-Naive Subjects.

HIV Infections

United States
Janssen, LP

Completed

A Randomized, Open, Comparative Multicenter Study of Initial Treatment With Intravenous Itraconazole Versus Amphotericin B Followed by Consolidation Treatment With Itraconazole Capsules in Patients With Blastomycosis or Histoplasmosis

HIV Infections | Histoplasmosis | Blastomycosis

United States
Yongyong MA

Recruiting

Daratumumab/Daratumumab and Hyaluronidase-fihj in Combination With Pomalidomide and Dexamethasone for the Treatment of Patients With Newly Diagnosed AL Amyloidosis: a Prospective, Multicenter, Single-arm Study

Amyloid Light-chain Amyloidosis

China
DermBiont, Inc.
Fortrea

Recruiting

A Randomized, Observer-Blinded, Placebo-Controlled Study on Safety and Efficacy of SM-030 in Adults With Melasma

Melasma

El Salvador
University Hospital, Bordeaux

Recruiting

Grade Analysis of Veins by MRI and CT in Post-Thrombotic Syndrome (GrAVITSPT)

Lower Limb Venous Thrombosis

France
Amsterdam UMC
ZonMw: The Netherlands Organisation for Health Research and Development

Not yet recruiting

Preeclampsia Intervention Netherlands (PI-NL)

Pre-Eclampsia | HELLP Syndrome | Pre-eclampsia or Eclampsia With Pre-existing Hypertension | HELLP | Pre-Eclampsia; Complicating Pregnancy | Pre-Eclampsia Onset Less Than 37 Weeks | Pre-Eclampsia as Antepartum Condition | Pre-Eclampsia; Affecting Fetus | HELLP Syndrome Complicating Pregnancy
Guangdong Provincial People's Hospital

Not yet recruiting

Randomized Study of ABC-14 Regimen Compared With "3+7" Standard Induction Therapy or AB-14 for ND AML

Acute Myeloid Leukemia

China
University of Aarhus
Aarhus University Hospital; University of Copenhagen; Gødstrup Hospital; Statens... and other collaborators

Not yet recruiting

The BEGIN Study Bifidobacterium Infantis to Newborns: Effects of Modulating the Gut Microbial Composition on Growth, Immune Function and Inflammatory Conditions - a Randomized Placebo-controlled Double-blinded Intervention Trial (BEGIN)

Healthy | Healthy Nutrition
C K S Teja Institute Of Dental Sciences & Research

Not yet recruiting

Comparative Evaluation of SMART Hall Technique vs. Conventional SS Crown in Primary Molars: A Randomized Clinical Trial (RCT)

Pain | Plaque, Dental | Caries,Dental | Gingival Bleeding

India
Satakunta University of Applied Sciences

Not yet recruiting

Mind Nutrition Study: Nutrition in the Prevention of Depressiveness and Sustaining Work Ability

Quality of Life | Depressive Symptoms | Eating Behavior | Nutrition, Healthy | Work-Related Condition

Finland
University Hospital, Rouen

Not yet recruiting

Functional Residual Capacity and Alveolar Recruitment in Single-lung Ventilation: a Randomized Study (OLVEELV)

Lung Injury
Louisiana State University Health Sciences Center...

Not yet recruiting

Effect of Sequencing on Outcome Measures

Muscle Weakness

United States
Merakris Therapeutics

Not yet recruiting

A Two-Part, Randomized Study of Dermacyte® Amniotic Wound Care Matrix

Diabetic Foot Ulcer
National Institute of Allergy and Infectious Diseases...
KBio Inc

Not yet recruiting

Phase 1, Randomized, Double-Blind, Placebo-controlled Study to Evaluate the Safety and Tolerability of an Enterovirus D68-specific Monoclonal Antibody in Healthy Adults

Enterovirus Infection

United States
Fujian Medical University Union Hospital

Recruiting

Multicenter Clinical Trial on the Effectiveness and Safety of Instillation of BCG and Alternative BCG Protocols for Intermediate and High-risk Non-muscle Invasive Bladder Cancer

Urinary Bladder Neoplasms | Treatment Outcome | Neoplasm Recurrence, Local | Multicenter Study | Immunotherapy, Active | BCG Vaccine

China
Changzhi Medical College

Not yet recruiting

Effectiveness of Stress Self-management Health Education Based on IMB Theory Among Nursing Students (IMB)

Psychological Stress | Nursing Students
Sun Yat-sen University

Recruiting

Fruquintinib With or Without HAI-FOLFOX for Refractory Colorectal Cancer

Colorectal Cancer

China
National Taiwan University Hospital

Recruiting

Reinterventions of Thoracic Endovascular Aortic Repair: a Retrospective Multicenter Cohort Study

Thoracic Endovascular Aortic Repair

Taiwan
Penn State University

Not yet recruiting

Optimizing Antibiotics Prescription: A Stepped-Wedge Randomized Trial

Antimicrobial Resistance
S.LAB (SOLOWAYS)
Center of New Medical Technologies

Not yet recruiting

Clinical Trial Protocol: Randomized Placebo-Controlled Pilot Study of GcMAF (Soloways TM) in Patients With Metastatic Breast Cancer

Breast Cancer

Russian Federation
Jazz Pharmaceuticals

Not yet recruiting

A Phase 3, Randomized, Open-label, Controlled Study Comparing the Efficacy and Safety of Zanidatamab to Trastuzumab, Each in Combination With Physician's Choice Chemotherapy, for the Treatment of Participants With Metastatic HER2-positive Breast Cancer

Metastatic HER2-positive Breast Cancer
Fudan University
Shenzhen Maternity & Child Healthcare Hospital

Not yet recruiting

A Study of the Intervention of Time-restricted Eating in High-risk Populations of GDM

Dietary Habits | Gestational Diabetes Mellitus | Lifestyle Intervention | Randomized Controlled Study
Columbia University
United States Department of Agriculture (USDA); California Walnut Commission

Not yet recruiting

Mechanistic Effect of Walnut Consumption on Sleep Quality

Poor Sleep Quality

United States
Sun Yat-sen University
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Recruiting

First-line Anlotinib Combined With Penpulimab for Advanced Pheochromocytoma: A Single-arm, Multicenter, Prospective Phase II Study

Pheochromocytoma

China
Ironshore Pharmaceuticals and Development, Inc

Not yet recruiting

Ph3 Multicenter, 3wk RDBPC Efficacy, Safety & PK Study of Evening Dosed MPH HCl ER Capsules (HLD200) in Children 4-5 Yr With ADHD

Attention Deficit Hyperactivity Disorder
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

A Study of SHR-A1811 in First-line Treatment of Patients With Advanced or Metastatic Non-small Cell Lung Cancer With HER2 Mutations

Non-Small Cell Lung Cancer With HER2- Mutations

China
Zhejiang Provincial People's Hospital

Not yet recruiting

Accuracy of an Artificial Intelligence-assisted Diagnostic System for Caries Diagnosis: a Prospective Multicenter Clinical Study

Dental Caries | Machine Learning | Diagnosis | Artificial Intellegence
Lu Hua

Not yet recruiting

Effect of Bupivacaine Liposome Anterior Serratus Deep Block on Chronic Pain After Breast Cancer Surgery: a Randomized Controlled Study

Breast Cancer Patients With Chronic Pain After Surgery

China
Heinrich-Heine University, Duesseldorf

Not yet recruiting

Work Package 3 Education for ICU Clinicians in Basic Palliative Care

ICU | Learning | Staff Attitude | Palliative Care, Patient Care
Peking Union Medical College Hospital

Not yet recruiting

Luspatercept Plus CsA vs CsA for the Treatment of Newly Diagnosed Non-Transfusion-Dependent NSAA

Aplastic Anemia

China
Beijing Cancer Prevention & Treatment Society
Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Recruiting

A Prospective, Multicenter, Non-interventional, Real-world Study to Characterize Changes in Molecular Markers After Three Weeks of Targeted Therapy With Oxitinib in EGFRm NSCLC (pre-FLAME)

Non Small Cell Lung Cancer

China
Gaziosmanpasa Research and Education Hospital

Recruiting

THE EFFECT OF VIRTUAL REALITY APPLICATIONS ON SITTING BALANCE IN HEMIPLEGIA: A RANDOMIZED CONTROLLED STUDY

Hemiplegia

Turkey
Zhejiang Chinese Medical University

Recruiting

A Randomized Controlled Study on the Treatment of Postherpetic Neuralgia in the Head and Face With Superficial Needling Combined With Electroacupuncture

Postherpetic Neuralgia | Electroacupuncture | Infrared Thermography

China
University of California, San Francisco

Not yet recruiting

Randomized Directly Observed Therapy Study to Interpret Clinical Trials of Doxy-PEP (DOT-Doxy-PEP)

Sexually Transmitted Diseases, Bacterial

United States
Peking University Third Hospital
Peking University; The First Affiliated Hospital of Anhui Medical University; First Affiliated Hospital, Sun Yat-Sen University and other collaborators

Recruiting

Multicenter Prospective Cohort Study of Twin Maternal-Child Dyads in China (ChiTwiMC)

Pre-Eclampsia | High Risk Pregnancy | Twin Pregnancy, Antepartum Condition or Complication | Pre-Term | Twin Dichorionic Diamniotic Placenta | Twin to Twin Transfusion as Antepartum Condition | Twin Placenta | Twin Monochorionic Diamniotic Placenta

China
Theodor Bilharz Research Institute

Recruiting

The Effects of Different Loading Doses of Dexmedetomidine on The Bispectral Index-Guided Propofol Sedation in Patients Undergoing Advanced Upper Gastrointestinal Endoscopic Procedures: A Randomized Control Study

Procedural Sedation | GIT Endoscopy

Egypt
M.D. Anderson Cancer Center

Not yet recruiting

A Multicenter Phase 1b/2 Study of Adagrasib, Cetuximab, and Cemiplimab for Metastatic Colorectal Cancer Harboring KRAS G12C Mutations

Metastatic Colorectal Cancer | KRAS G12C Mutations

United States
KidSIM Simulation Program
University of Alabama at Birmingham; Columbia University; University of Southern... and other collaborators

Not yet recruiting

Evaluation of the InterFACE-AR System for Cardiopulmonary Arrest: A Multicenter, Randomized Controlled Trial (InterFACE-AR)

Cardiac Arrest | Cardiopulmonary Arrest
The University of Texas Health Science Center at...

Recruiting

Evaluating Sensory-Adapted Dental Care in Children With Sensory Processing Disorders

Sensory Processing Disorder

United States
University of Calgary

Not yet recruiting

Ablation Index in Standard vs. High Power Radiofrequency Ablation for Typical Atrial Flutter: A Randomized Study (AITAF) (AITAF)

Atrial Flutter | Atrial Flutter Typical | Cavotricuspid Isthmus Dependent Macroreentry Tachycardia

Canada
Tianjin Medical University Cancer Institute and...

Not yet recruiting

A Prospective, Single-arm, Multicenter Phase II Clinical Study of HAIC in Combination With Adebrelimab and Bevacizumab for Potentially Resectable Hepatocellular Carcinoma

Hepatocellular Carcinoma | Adebrelimab

China
Peking University

Recruiting

The Effectiveness of Group-Delivered Guided Written Exposure Therapy for PTSD and Subclinical PTSD Among Chinese Adolescents : A Pilot Study

PTSD

China
CHU de Quebec-Universite Laval

Recruiting

Impact of Capillaroscopy on the Management of Undifferentiated Connective Tissue Disease

Undifferentiated Connective Tissue Diseases

Canada
Duke University
University of Pennsylvania; National Heart, Lung, and Blood Institute (NHLBI)

Not yet recruiting

Prospective Multicenter Research on Donor and Recipient Management Strategies to Improve Lung Transplant Outcomes (PROMISE)

Lung Transplant Rejection | Lung Transplant Failure | Lung Transplant; Complications | Lung Transplant; Infection or Inflammation

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