Search clinical trials for: Natural Killer Cells

Total 14311 results

National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Collection and Storage of Umbilical Cord Stem Cells for Treatment of Sickle Cell Disease

Sickle Cell Disease | Sickle Cell Trait

United States
National Institute of Allergy and Infectious Diseases...
Medstar Health Research Institute

Recruiting

Studies of the Pathogenesis of HIV Infection in Human Peripheral Blood Cells and/or Body Fluids in People Living With and Without HIV

HIV | Infectious Diseases | Immunodeficiencies

United States
National Institute of Allergy and Infectious Diseases...

Recruiting

Study of Autoimmune Lymphoproliferative Syndrome (ALPS)

Benign Lymphoproliferative Disorder

United States
National Institute of Allergy and Infectious Diseases...

Recruiting

Recruitment and Apheresis Collection of Peripheral Blood Hematopoietic Stem Cells, Mononuclear Cells and Granulocytes

Granuloma | Granulomatous Disease, Chronic | Leukocyte Disease | Genetic Disease, X-Linked | Genetic Disease, Inborn

United States
AstraZeneca
Innate Pharma

Active, not recruiting

Assessment of Efficacy and Safety of Monalizumab Plus Cetuximab Compared to Placebo Plus Cetuximab in Recurrent or Metastatic Head and Neck Cancer (INTERLINK-1)

Squamous Cell Carcinoma of the Head and Neck

United States, France, Italy, Spain, Belgium, Canada, Taiwan, Switzerland, Korea, Republic of, Japan, Poland, Russian Federation, United Kingdom, Austria, Brazil, Germany, Netherlands, Portugal, Australia, Philippines, Bulgaria, G... and more
Noah Merin
Teva Branded Pharmaceutical Products R&D, Inc.; Miltenyi Biomedicine GmbH

Active, not recruiting

Haploidentical Stem Cell Transplant With Prophylactic Natural Killer DLI for Lymphoma, Multiple Myeloma, and CLL

Lymphoma | Multiple Myeloma | Hodgkin Lymphoma | Chronic Lymphocytic Leukemia | CLL

United States
National Institute on Aging (NIA)

Completed

Study of Skin Cells That Stop Replicating (Senescent) During Wound Healing

Healthy Volunteers

United States
National Cancer Institute (NCI)

Active, not recruiting

Retrospective Analysis of a Drug-Metabolizing Genotype in Cancer Patients and Correlation With Pharmacokinetic and Pharmacodynamics Data

Melanoma | Breast Cancer | Lung Cancer | Prostate Cancer | Cutaneous T-Cell Lymphoma

United States
National Cancer Institute (NCI)

Enrolling by invitation

Harvesting Cells for Experimental Cancer Treatments

Melanoma | Breast Cancer | Non-Small Cell Lung Cancer | Metastatic Cancer | Gastrointestinal Cancer

United States
National Institute of Neurological Disorders and...

Completed

Study of Specimens Obtained During Epilepsy Surgery

Epilepsy

United States
National Institutes of Health Clinical Center (CC)

Completed

Collection of Bone Marrow From Healthy Volunteers and Patients for the Production of Clinical Bone Marrow Stromal Cell (BMSC) Products

Bone Marrow Stromal Cells

United States
National Cancer Institute (NCI)

Enrolling by invitation

Leukapheresis for CAR or Adoptive Cell Therapy Manufacturing

Lymphoma | Leukemia | Non-Hodgkin's Lymphoma | Acute Lymphoblastic Leukemia | Diffuse Large B Cell Lymphoma

United States
National Cancer Institute (NCI)

Completed

Specimen Collection for Agricultural Health Study Cohort Pesticide Exposure Study

Leukemia | Multiple Myeloma | MGUS | Monoclonal B-Cell Lymphocytosis

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effect of Fasting and Refeeding on T-cell Fate

Inflammation | Asthma

United States
National Cancer Institute (NCI)

Active, not recruiting

Pembrolizumab and Recombinant Interleukin-12 in Treating Patients With Solid Tumors

Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
ImmunityBio, Inc.

Terminated

QUILT-3.009: Patients With Stage III (IIIB) or Stage (IV) Merkel Cell Carcinoma (MCC)

Stage IIIB Merkel Cell Carcinoma | Stage IV Merkel Cell Carcinoma

United States
Vaxcell Bio, Co., Ltd.

Completed

Natural Killer (NK) Cell Therapy in Locally Advanced HCC

Locally Advanced Hepatocellular Carcinoma

Korea, Republic of
The First Hospital of Jilin University

Completed

Natural Killer(NK) Cell Combined With Programmed Death-1(PD-1) Antibody as Second Line Therapy for Advanced Driver Mutation Negative Non-small Cell Lung Cancer

Non-small Cell Lung Cancer

China
National Cancer Institute (NCI)

Active, not recruiting

Cetuximab and Recombinant Interleukin-12 in Treating Patients With Squamous Cell Carcinoma of the Head and Neck That is Recurrent, Metastatic, or Cannot Be Removed by Surgery

Recurrent Head and Neck Squamous Cell Carcinoma | Metastatic Head and Neck Squamous Cell Carcinoma | Unresectable Head and Neck Squamous Cell Carcinoma

United States
Ain Shams University

Active, not recruiting

Implication of CCR4-NOT Complex Subunit 7 Expression in Natural Killer Cell Resistance in Metastatic Breast Cancer (CCR4-NOT)

Metastatic Breast Cancer

Egypt
NKGen Biotech, Inc.

Terminated

Safety of SNK01 in Subjects With Alzheimer's Disease (ASK-AD) (ASK-AD)

Alzheimer Disease | Neuro-Degenerative Disease

Mexico
Washington University School of Medicine
National Cancer Institute (NCI); American Society of Clinical Oncology; ImmunityBio... and other collaborators

Terminated

Cytokine-induced Memory-like NK Cells in Patients With Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)

Leukemia, Myeloid, Acute

United States
National Institute of Environmental Health Sciences...

Completed

Cytochrome P450 Epoxygenase Pathway Regulation of Macrophage Function

Lung Inflammation | Polymorphism

United States
Fate Therapeutics

Terminated

Long-term, Non-interventional, Observational Study Following Treatment With Fate Therapeutics FT500 Cellular Immunotherapy

Melanoma | Lymphoma | Renal Cell Carcinoma | Cervical Cancer | Head and Neck Cancer | Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | NSCLC | Advanced Solid Tumor | Small-cell Lung Cancer | HER2-positive Breast Cancer | Pancreas Cancer | Urothelial Carcinoma | Merkel Cell Carcinoma | Microsatellite Instability and other conditions

United States
Michael Pulsipher, MD
Seattle Children's Hospital; Nationwide Children's Hospital

Enrolling by invitation

Donor-Derived Ex-Vivo Expanded Natural Killer Cell Infusions in Children and Young Adults With High Risk Acute Myeloid Leukemia Receiving Myeloablative HLA-Haploidentical Hematopoietic Cell Transplant (EXCEL)

Acute Myeloid Leukemia

United States
University of Nebraska

Withdrawn

Donor Enriched Activated NK Cell Infusion Post Haploidentical Stem Cell Transplant for Refractory Myeloid Malignancies

Leukemia
NKGen Biotech, Inc.

Active, not recruiting

Safety of SNK01 in Subjects With Pathologically Confirmed Metastatic and/or Unresectable Cancer Refractory to Conventional Therapy

Metastatic Cancer | Advanced Solid Tumor | Advanced Cancer | Solid Tumor, Adult | Refractory Cancer | Recurrent Cancer | Unresectable Carcinoma

United States
TVAX Biomedical

Completed

Study To Test the Safety and Efficacy of TVI-Brain-1 As A Treatment for Recurrent Grade IV Glioma

Glioblastoma Multiforme | Grade IV Astrocytoma | Grade IV Glioma

United States
TVAX Biomedical

Completed

Phase I/II Study To Test The Safety and Efficacy of TVI-Brain-1 As A Treatment For Recurrent Grade IV Glioma

Glioma | Glioblastoma Multiforme | High Grade Astrocytoma

United States
Naturex SA
Artialis; Vizera d.o.o.

Completed

Turmeric Efficacy for Mobility and Joint Function (T-MOTION)

Joint Pain | Knee Discomfort

Croatia, Slovenia
Seoul National University Hospital

Completed

MG4101 for Refractory or Relapsed AML

Acute Myeloid Leukemia

Korea, Republic of
National Cancer Institute (NCI)

Completed

Investigation of the Human Immune Response in Normal Subjects and Patients With Disorders of the Immune System and Cancer

B-Cell Lymphoma | Myeloma | T-cell Lymphoma | ATL

United States
Celularity Incorporated

Withdrawn

CYNK-001 IV and IC in Combination With IL2 in Surgical Eligible Recurrent GBM With IDH-1 Wild Type (CYNK001GBM02)

Glioblastoma | Glioblastoma Multiforme | Giant Cell Glioblastoma | Astrocytoma, Grade IV

United States
Lo.Li.Pharma s.r.l

Completed

Effect of Natural Compounds on the Severity of HPV-induced Cervical Lesions

Papilloma | Cervix Lesion

Italy
Jennifer Marler, MD
UserWise, LLC

Completed

Pivot Breath Sensor Performance Study

Smoking Cessation | Smoking, Tobacco

United States
National Institute of Allergy and Infectious Diseases...

Completed

Study of Mast Cell Precursors

Healthy Volunteer | Mastocytosis

United States
The Canadian College of Naturopathic Medicine
Ottawa Hospital Research Institute; Vitazan Professional; New Roots Herbal

Terminated

Dietary Supplements for COVID-19

Covid19

Canada
St. Jude Children's Research Hospital
Assisi Foundation; Cookies for Kids' Cancer

Completed

Therapy for Pediatric Relapsed or Refractory Precursor B-Cell Acute Lymphoblastic Leukemia and Lymphoma

Recurrent B-Cell Childhood Acute Lymphoblastic Leukemia | Recurrent Childhood B-Lymphoblastic Lymphoma

United States
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Stem Cell Collection for Adult Volunteers

Sickle Cell

United States
National Cancer Institute (NCI)

Completed

Optimal Methods of Disease Detection in Children and Young Adults With Acute Lymphoblastic Leukemia in the Pediatric Oncology Branch

Leukemia, Lymphoblastic, Acute | ALL, Childhood

United States
National Institute of Allergy and Infectious Diseases...

Terminated

Collection of Peripheral Blood Stem Cells Using G-CSF and Plerixafor in Normal Volunteers

Normal Physiology

United States
SMT bio Co., Ltd.

Completed

Allogeneic NK Cell ("SMT-NK") in Combination With Pembrolizumab in Advanced Biliary Tract Cancer

Biliary Tract Cancer

Korea, Republic of
Queen's University, Belfast

Completed

Effect of Fruit and Vegetable Consumption on Immune Function in the Elderly (ADIT)

Immune Function

United Kingdom
Fate Therapeutics

Completed

FATE-NK100 as Monotherapy and in Combination With Monoclonal Antibody in Subjects With Advanced Solid Tumors

Melanoma | Renal Cell Carcinoma | Hepatocellular Carcinoma | Colorectal Cancer | Pancreatic Cancer | Non Small Cell Lung Cancer | Advanced Solid Tumors | HER2-positive Breast Cancer | Head and Neck Squamous Cell Carcinoma | HER2 Positive Gastric Cancer | EGFR Positive Solid Tumor

United States
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Single vs Double Umbilical Cord Blood Transplants in Children With High Risk Leukemia and Myelodysplasia (BMT CTN 0501)

Myelodysplastic Syndrome | Acute Lymphocytic Leukemia | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia | Natural Killer Cell Lymphoblastic Leukemia/Lymphoma

United States, Australia, Canada
Chinese Academy of Sciences
National Natural Science Foundation of China; The First Affiliated Hospital...

Active, not recruiting

Mesenchymal Stem Cells (MSCs) - Like Cell Transplantation in Women With Primary Ovarian Insufficiency (MSCLCTWPOI)

Primary Ovarian Insufficiency

China
Henan Cancer Hospital
Henan Provincial People's Hospital; Hebei Medical University Fourth Hospital; Tangshan People's Hospital and other collaborators

Terminated

Chemotherapy Combined Autologous Cytokine-induced Killer Cells in Naive Stage IV EGFR-wild Type Lung Adenocarcinoma

Lung Adenocarcinoma

China
NKGen Biotech, Inc.

Withdrawn

Safety and Preliminary Efficacy of SNK01 in Combination With Trastuzumab or Cetuximab in Subjects With Advanced HER2 or EGFR Cancers

Sarcoma | Cervical Cancer | Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | Metastatic Cancer | Bladder Cancer | Triple Negative Breast Cancer | Advanced Solid Tumor | HER2-positive Breast Cancer | Head and Neck Squamous Cell Carcinoma | EGF-R Positive Non-Small... and other conditions
Shandong Provincial Hospital

Active, not recruiting

The Relationship Between NK Cell and Graves' Disease

Graves Disease

China
Radboud University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development; Dutch...

Active, not recruiting

Melanoma Patients Immunized With Natural DenDritic Cells (MIND-DC)

Melanoma (Skin)

Netherlands

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