Search clinical trials for: Population pharmacokinetic (Pop PK)

Total 17743 results

Hartford Hospital
Melinta Therapeutics, LLC

Not yet recruiting

Rezafungin PK in Patients on ECMO

Sepsis

United States
Joseph L. Kuti, PharmD
Shionogi Inc.

Recruiting

Cefiderocol PK in Patients on ECMO

Sepsis

United States
Joseph L. Kuti, PharmD
Merck Sharp & Dohme LLC

Completed

Imipenem/Cilastatin/Relebactam PK in ECMO

Sepsis

United States
Radboud University Medical Center
Merck Sharp & Dohme LLC; ZonMw: The Netherlands Organisation for Health Research...

Recruiting

Study on PhArmacokinetics of First liNe Antiretrovirals in Healthy Breastfeeding Volunteers (PANNA-B PK)

Hiv

Netherlands
Brugmann University Hospital

Recruiting

Does the Thrombin Generation Test Performed During the Pharmacokinetic Profile of the Substitutive Factor VIII Bring Benefits to the Personalized Treatment of Pediatric Patients and Adult Hemophilia A Patients Under Prophylaxis ?

Hemophilia

Belgium
Alebund Pty Ltd

Completed

A Safety, Tolerability, and Pharmacokinetics Study of AP303 in Healthy Subjects

Healthy Subjects

Australia
Philip Morris Products S.A.

Completed

Nicotine Pharmacokinetics of THS Single Use of a Regular or a Menthol Stick Compared to CIG

Smoking, Tobacco

United Kingdom
Emmaus Medical, Inc.

Completed

Pharmacokinetics and Safety of Endari (L-glutamine) in Sickle Cell Disease Patients

Sickle Cell Disease | Pharmacokinetics

United States
Vertanical GmbH

Completed

Single and Multiple Dose Study of VER-01 in Healthy Volunteers

Healthy

Austria
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

To Assess Pharmacokinetics, Safety and Tolerability of TEV-48125 in Japanese and Caucasian Healthy Subjects After a Single Subcutaneous (SC) Administration of TEV-48125

Pharmacokinetics

United States
Merckle GmbH

Completed

PK, PD, Safety and Tolerability of Lipegfilgrastim in Healthy Japanese and Caucasian Participants

Pharmacokinetics | Pharmacodynamics

United Kingdom
Tris Pharma, Inc.
Forest Laboratories

Completed

A Clinical Study to Evaluate the Effect of Renal Impairment on the Pharmacokinetics of Cebranopadol

Pharmacokinetic

United States
MyMD Pharmaceuticals, Inc.

Completed

Single Ascending-dose Study to Evaluate Safety, Tolerability, and PK of MYMD1 in Healthy Male Adult Subjects

Undefined

United States
Philip Morris Products S.A.

Completed

Exploratory THS 2.1 Nicotine Pharmacokinetics and Safety Study

Smoking

United Kingdom
Capital Medical University
University of Oxford; Centers for Disease Control and Prevention, China; Beijing...

Completed

A Pharmacokinetics Study of Favipiravir in Patients With Severe Influenza

Critical Illness | Influenza | Influenza, Human

China
Xequel Bio, Inc.
Medical University of South Carolina; Spartanburg Regional Healthcare System

Completed

Safety Study to Examine the Systemic Exposure of Granexin® Gel After Topical Application to Diabetic Foot Ulcers

Diabetic Foot Ulcers

United States
Acorda Therapeutics

Completed

A Study of the Pulmonary Safety and Pharmacokinetics of Zolmitriptan Inhalation Powder

Migraine

United States
Jeffrey A. Feinstein
University of Colorado, Denver; Children's Hospital of Philadelphia; Seattle... and other collaborators

Completed

Pharmacokinetic Study of Sub-q and IV Treprostinil in Kids With Pulmonary Arterial Hypertension (PAH) (PKRemodulin)

Pulmonary Arterial Hypertension

United States
Lumara Health, Inc.

Completed

Pharmacokinetic Study of Makena® (Hydroxyprogesterone Caproate Injection, 250 mg/mL) and Its Metabolites in Blood

Pregnancy

United States
Oswaldo Cruz Foundation
Ministry of Health, Brazil

Completed

Pharmacokinetics of the Tablet Formulation of Lopinavir/r as Standard and Increased Dosage During Pregnancy

HIV Infections | Pregnancy

Brazil
Kirby Institute
Chelsea and Westminster NHS Foundation Trust

Completed

The Intensive Pharmacokinetics Sub-study of Encore1 (ENCORE1-PK)

HIV Infection

Argentina, South Africa, Thailand, United Kingdom
Javelin Pharmaceuticals

Completed

Open-Label, Single-Dose Study to Evaluate the Safety and PK of DIC075V in Subjects With Renal Insufficiency and Hepatic Impairment Compared to Healthy Subjects and Evaluate the Safety and Pharmacokinetics of HPβCD When Administered in DIC075V Compared to Sporanox® in Healthy Subjects

Hepatic Insufficiency | Healthy | Renal Insufficiency, Chronic

United States, United Kingdom
Javelin Pharmaceuticals

Completed

Study to Assess Effects of Age, Weight, and Body Composition on the Pharmacokinetics of IV Diclofenac Sodium (DFC-PK-008)

Healthy

United States
Javelin Pharmaceuticals

Unknown

Determination of Drug Interactions of Certain Nasal Medications With Intranasal Ketamine

Pharmacokinetics

United States
Mayo Clinic
National Institute of Neurological Disorders and Stroke (NINDS)

Recruiting

Long-term Effects of COVID-19

COVID-19 | SAR-CoV-2

United States
Assembly Biosciences

Not yet recruiting

A Study to Assess the Safety, Pharmacokinetics, and Antiviral Activity of ABI-5366 in Healthy Participants and Participants Seropositive for HSV-2 With Recurrent Genital Herpes

Recurrent Genital Herpes Simplex Type 2

New Zealand
Linda Van Eldik
National Institute on Aging (NIA); Duke Clinical Research Institute

Completed

MW151-101: First-in-human Study of MW151

Drug Toxicity

United States
Universitaire Ziekenhuizen KU Leuven
KU Leuven

Completed

Pharmacokinetic Study of Paracetamol in Patients Over 80 Years Hospitalized to an Acute Geriatric Ward

Pain

Belgium
GlaxoSmithKline

Completed

Co-Administration Of Fosamprenavir With Methadone: A Drug Interaction Study.

Healthy Subjects

United States
Riphah International University

Not yet recruiting

Effects of Functional Progressive Strength Training in Children With Spastic Cerebral Palsy

Spastic Cerebral Palsy

Pakistan
M.D. Anderson Cancer Center

Completed

Trientine and Carboplatin in Advanced Malignancies

Advanced Cancers

United States
Novartis Pharmaceuticals

Terminated

A Study to Evaluate the Effects of ASA404 Alone or in Combination With Taxane-based Chemotherapies on the Pharmacokinetics of Drugs in Patients With Advanced Solid Tumor Malignancies

Solid Tumor Malignancies

United States
Université Catholique de Louvain

Recruiting

Population Pharmacokinetics and Pharmacodynamics of Beta-lactams of Interest in Adult Patients From Intensive Care Units (Pop-PK/PD)

Pharmacokinetics | Infection | Infection, Bacterial | Anti-Bacterial Agents | Drug Monitoring | Infections, Respiratory

Belgium
Novartis Pharmaceuticals

Completed

Study to Evaluate Panobinostat (DACi) Pharmacokinetics and Safety in Solid Tumors and Varying Renal Function

Advanced Solid Tumors

Switzerland, Netherlands, United States, United Kingdom
sigma-tau i.f.r. S.p.A.
CPR Pharma Services Pty Ltd, Australia

Completed

A Pharmacokinetic (PK) Trial in Healthy Asian and Caucasian Volunteers Investigating the PK Profile of Eurartesim™

Malaria, Falciparum

Australia
Mylan Inc.
Mylan GmbH

Completed

Phase I - Pharmacokinetic Comparability Study in Healthy Male Volunteers

Healthy

Netherlands
Organon and Co
CRS Mannheim GmbH

Completed

A Trial to Assess the Pharmacokinetic Profile (e.g., Uptake, Distribution and Excretion of a Substance in the Body) of Nomegestrol Acetate (NOMAC), Estradiol (E2) and Estrone (E1) After Multiple and Single Dose Administration of the Combined Oral Contraception NOMAC-E2 (COMPLETED)(P05822)

Healthy
Acerta Pharma BV

Completed

A Study to Evaluate the Effect of Gastric pH on Acalabrutinib Pharmacokinetics (PK) in Healthy Adult Participants

Healthy Volunteers

United States
GlaxoSmithKline

Completed

Pharmacokinetic (PK) Profiles of Tenofovir Disoproxil Fumarate (TDF) 300 mg in Healthy Chinese Subjects (PK of TDF)

Hepatitis B, Chronic

China
GlaxoSmithKline

Completed

Study Of Single And Ten Day Repeat Atopical Applications Of GW842470X Cream On The Skin Of Patients With Atopic Dermatitis

Dermatitis, Atopic

Germany
Chulalongkorn University

Completed

Clinical Outcomes of Low Dose PK-guided EHL FVIII Concentrates Versus Standard Prophylaxis in Severe Haemophilia A

Severe Hemophilia A Without Inhibitor

Thailand
AstraZeneca

Completed

A Study of AZD8233 in Participants With Dyslipidemia. (HAYATE)

Dyslipidemia

Japan
AstraZeneca

Completed

A Study of Single and Multiple Ascending Doses of TC-5214 in Japanese Healthy Elderly Male and Female Volunteers

Healthy

Japan
Pfizer

Completed

A Trial To Assess The Safety, Tolerability, Pharmacokinetics, And Pharmacodynamics Of Single Doses Of PF-04937319 In Subjects With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

United States
The Aurum Institute NPC
Johns Hopkins University; Weill Medical College of Cornell University; University...

Recruiting

Safety and Tolerability of 1 Month Daily (1HP) and 3 Months Weekly (3HP) Isoniazid and Rifapentine With Pharmacokinetics of Dolutegravir (DTG) in Pregnant People With HIV (DOLPHIN Moms)

Pregnancy | HIV Seropositivity | Tuberculosis Infection

South Africa
Pakistan Institute of Living and Learning
Fatima Jinnah Women University

Not yet recruiting

Universally Delivered Interventions for Young People (Mindset-PK)

Distress, Emotional

Pakistan
Aga Khan University Hospital, Pakistan

Unknown

Apneic Oxygenation in the Emergency Department (ApOxED)

Apneic Oxygenation
University of Colorado, Denver

Completed

Effects of Sofosbuvir/Ledipasvir Treatment on the Pharmacokinetics and Renal Safety of Tenofovir

Hepatitis C and HIV Coinfection

United States
Asan Medical Center

Completed

Population Pharmacokinetics/Pharmacodynamics (PK/PD) of Microemulsion Propofol in Healthy Volunteers

Healthy

Korea, Republic of
Nanexa AB
Profil Institut für Stoffwechselforschung GmbH

Not yet recruiting

Phase 1 Study Assessing the Pharmacokinetics of NEX-22A in Subjects With T2D

Type 2 Diabetes

3

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