Search clinical trials for: Primary Immunodeficiency Diseases

Total 379468 results

National Cancer Institute (NCI)

Completed

Chemotherapy and HAART to Treat AIDS-related Primary Brain Lymphoma

AIDS-Related-Primary Central Nervous System Lymphoma

United States
Assiut University

Completed

Minipooled-IVIG in Primary Immunodeficiency Disease

Primary Immunodeficiency

Egypt
Therapure Biopharma Inc

Unknown

Study of PlasmaCap IG in Adults and Children With PIDD

Primary Immune Deficiency Diseases (PIDD)

United States, Canada
Leadiant Biosciences, Inc.

Completed

EZN-2279 in Patients With ADA-SCID

Severe Combined Immunodeficiency | ADA-SCID | Adenosine Deaminase Deficiency

United States
KalVista Pharmaceuticals, Ltd.

Completed

A Single Dose Safety, Tolerability, Pharmacokinetic and Food Effect Study of KVD900 in Healthy Volunteers

Hereditary Angioedema

United Kingdom
Grifols Therapeutics LLC

Withdrawn

Study Evaluating IGSC 20% Flexible Dosing in Treatment-Experienced and Treatment-Naive Subjects With Primary Immunodeficiency

Primary Immunodeficiency

United States
CSL Behring

Completed

Safety and Tolerability of Higher Infusion Parameters of IgPro20 (Hizentra) in Subjects With Primary Immunodeficiency (PID)

Primary Immunodeficiency

United States, Canada
Medical College of Wisconsin

Withdrawn

Treatment of Granulomatous and Lymphocytic Interstitial Lung Disease in Patients With Common Variable Immunodeficiency

Granulomatous and Lymphocytic Interstitial Lung Disease
Octapharma

Completed

Study to Evaluate the Efficacy, Tolerability and Safety of Octanorm in Patients With Primary Immunodeficiency Diseases

Primary Immune Deficiency Disorder

Russian Federation
Ottawa Hospital Research Institute
Octapharma

Unknown

Safety, Tolerability, Patient Satisfaction and Cost of 16.5% Subcutaneous Immunoglobulin (Cutaquig®) Treatment

Primary Immunodeficiency Disease | Secondary Immunodeficiency

Canada
National Cancer Institute (NCI)

Completed

Breadth of Donor Options for People With Inherited Diseases Requiring Allogeneic Hematopoietic Stem Cell Transplant in the Era of Alternative Donor Transplants Using Post-Transplantation Cyclophosphamide

Common Variable Immunodeficiency | Primary T-cell Immunodeficiency Disorders

United States
University Hospital, Strasbourg, France

Completed

Severe PID With Lymphoproliferation and Neutropenia (DICEP)

Primary Immune-Deficiency (PID) Common Variable Immune Deficiency (CVID)

France
Children's Hospital of Fudan University
The First Affiliated Hospital of Zhengzhou University; Shanghai Children's... and other collaborators

Active, not recruiting

Multi-center Clinical Study of Cord Blood Stem Cell Transplantation for SCID

Severe Combined Immunodeficiency Disease

China
BioCryst Pharmaceuticals

Completed

A Relative Bioavailability Study of Two Formulations of BCX7353

Hereditary Angioedema

United Kingdom
Emory University

Completed

Bone Marrow Transplant With Abatacept for Non-Malignant Diseases

Sickle Cell Disease | Fanconi Anemia | Hurler Syndrome | Chronic Granulomatous Disease | Severe Congenital Neutropenia | Hemophagocytic Lymphohistiocytosis | Wiskott-Aldrich Syndrome | Diamond-Blackfan Anemia | Severe Aplastic Anemia | Glanzmann Thrombasthenia | Shwachman-Diamond Syndrome | Thalassemia Major | Leukocyte... and other conditions

United States
National Human Genome Research Institute (NHGRI)

Withdrawn

Quality of Life and Neuropsychiatric Sequelae in Patients Treated With Gene Therapy for ADA-SCID and in Their Parents

ADA-SCID
National Human Genome Research Institute (NHGRI)

Completed

Gene Transfer Therapy for Severe Combined Immunodeficieny Disease (SCID) Due to Adenosine Deaminase (ADA) Deficiency

Severe Combined Immunodeficiency Syndrome

United States
National Institute of Allergy and Infectious Diseases...

Unknown

Lentiviral Gene Transfer for Treatment of Children Older Than 2 Years of Age With X-Linked Severe Combined Immunodeficiency (LVXSCID-OC)

X-Linked Combined Immunodeficiency Diseases

United States
Children's Hospital Medical Center, Cincinnati
Hoxworth Blood Center

Terminated

CD34+ Stem Cell Infusion to Augment Graft Function

Bone Marrow Failure | Waning Donor Chimerism | Waning Immune Function | Primary Immunodeficiency Disease(s)

United States
Institut de Médecine et d'Epidémiologie Appliquée...

Completed

Kinetics of HIV-RNA Decay in Seminal Plasma of Men Treated by Dolutegravir at the Time of Primary HIV Infection (DOLUPRIM)

HIV Infection Primary
University of California, San Diego
National Institutes of Health (NIH); Centers for Disease Control and Prevention

Completed

Implementation of Nucleic Acid Amplification Testing Screening to Identify Acute and Early HIV Infection

Acute HIV Infection

United States
Grifols Therapeutics LLC

Completed

Safety and Pharmacokinetics of IGSC 20% in Subjects With Primary Immunodeficiency

Primary Immunodeficiency

United States, Canada
Unity Health Toronto

Unknown

Using Electronic Medical Record Data to Improve HIV Primary Care

HIV/AIDS | Electronic Health Records | Quality of Health Care

Canada
Roswell Park Cancer Institute

Completed

Fludarabine Phosphate, Melphalan, and Low-Dose Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Primary Myelofibrosis | Polycythemia Vera | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma and other conditions

United States
Shenzhen Geno-Immune Medical Institute

Unknown

Gene Transfer for ADA-SCID Using an Improved Lentiviral Vector (TYF-ADA)

Adenosine DeAminase Severe Combined ImmunoDeficiency (ADA-SCID)

China
Shenzhen Geno-Immune Medical Institute

Unknown

Gene Transfer for SCID-X1 Using a Self-inactivating Lentiviral Vector （TYF-IL-2Rg）

SCID, X Linked

China
Kuwait Society for Allergy and Clinical Immunology

Completed

Primary Immunodeficiency in Kuwait

Primary Immune Deficiency Disorder

Kuwait
MUC Research GmbH
Merck Sharp & Dohme LLC; Pfizer; AbbVie; German Center for Infection Research

Completed

New Era Study: Treatment With Multi Drug Class (MDC) HAART in HIV Infected Patients (NewEra)

HIV Infections

Germany
BriovaRx Infusion Services
Bio Products Laboratory (BPL)

Completed

Monitoring of 5% Treatment Naïve Intravenous Immunoglobulin (IVIg) Primary Immunodeficiency Disease (PIDD) Patients Using the CareExchange® System: A Pilot Study Using 5% Gammaplex® IVIg in the Home Setting

Primary Immunodeficiency Disease (PIDD)

United States
BriovaRx Infusion Services

Terminated

Gamma Globulin Observations and Outcomes Database for Patients With Primary Immunodeficiency Disease (GOOD-SHEPARD-PI)

Primary Immune Deficiency Disorder

United States
University of Arkansas

Withdrawn

Pancreatic Cancer Screening of High-Risk Individuals in Arkansas

Pancreatic Neoplasms | Colorectal Neoplasms, Hereditary Nonpolyposis | BRCA1 Gene Mutation | BRCA2 Gene Mutation | Hereditary Pancreatitis | Ataxia Telangiectasia | Peutz-Jegher's Syndrome | Familial Atypical Mole-Malignant Melanoma Syndrome

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Total-Body Irradiation Followed By Cyclosporine and Mycophenolate Mofetil in Treating Patients With Severe Combined Immunodeficiency Undergoing Donor Bone Marrow Transplant

Severe Combined Immunodeficiency | Adenosine Deaminase Deficiency | Immune System Disorder | Autosomal Recessive Disorder | Purine-Nucleoside Phosphorylase Deficiency | Severe Combined Immunodeficiency With Absence of T and B Cells | X-Linked Severe Combined Immunodeficiency

United States
University Hospital, Lille
Shire

Completed

IgG Level in Primary Immunodeficiency Switching From Standard SCIG to Every Other Week HyQvia

Primary Immunodeficiency

France
Octapharma

Completed

Octagam 5% Versus Comparator Post Marketing Trial

Primary Immune Deficiency Disorder

United States
Rockefeller University

Terminated

Viral and Host Factors in the Transmission and Pathogenesis of HIV

HIV Infections

United States
Octapharma

Completed

A Study to Compare Quality of Life and Satisfaction in Primary Immunodeficient Patients Treated With Subcutaneous Injections of Gammanorm® 165 mg/mL Administered With Two Different Delivery Devices: Injections Using Pump or Rapid Push

Primary Immunodeficiency

United Kingdom, Australia, Germany, Italy
CHU de Reims

Unknown

Tolerance and Patients' Satisfaction With IGHy

Secondary or Primary Immunodeficiency

France
Johns Hopkins University

Terminated

Cell-Based Approaches For Modeling and Treating Ataxia-Telangiectasia

Ataxia-Telangiectasia (A-T)

United States
Weill Medical College of Cornell University
Novartis Pharmaceuticals

Terminated

Thrombocytopenia and Bleeding in Wiskott-Aldrich Syndrome (WAS) Patients (WAS)

Bleeding | Thrombocytopenia | Wiskott-Aldrich Syndrome

United States
GlaxoSmithKline

Completed

Targeted Literature Review and Subject Interviews in Wiskott-Aldrich Syndrome (WAS)

Wiskott-Aldrich Syndrome

United States
Orpha Labs

Completed

Study of ORL-1F (L-fucose) in Patients With Leukocyte Adhesion Deficiency Type II

Leukocyte Adhesion Deficiency, Type II
Boston University
National Institute of Allergy and Infectious Diseases (NIAID); University of...

Completed

Rapid Initiation of Antiretroviral Therapy to Promote Early HIV/AIDS Treatment in South Africa (RapIT Study) (RapIT)

HIV

South Africa
Federal Research Institute of Pediatric Hematology...

Unknown

A Trial of Plerixafor/G-CSF as Additional Agents for Conditioning Before TCR Alpha/Beta Depleted HSCT in WAS Patients

Hematopoietic Stem Cell Transplantation | Wiskott-Aldrich Syndrome | Graft Failure

Russian Federation
X4 Pharmaceuticals

Withdrawn

A Retrospective and Prospective Natural History Study of Patients With WHIM Syndrome

WHIM Syndrome
University Hospital, Caen

Unknown

ENCAPSID Study : ENCApsulated Bacterial Infection and Primary, Secondary ImmunoDeficiency (ENCAPSID)

Immune Deficiency

France
CSL Behring

Completed

A Study to Evaluate the Long-term Clinical Safety and Efficacy of Subcutaneously Administered C1-esterase Inhibitor in the Prevention of Hereditary Angioedema

Hereditary Angioedema Types I and II

United States, Spain, Germany, Australia, Canada, Czechia, Hungary, Israel, Italy, Romania, United Kingdom
Fondation Ophtalmologique Adolphe de Rothschild

Terminated

Genetic Factors of Idiopathic Polypoidal Vasculopathies in the ATM Gene (Ataxia Telangiectasia Mutated) (ATM)

Choroidal Neovascularization

France
University of California, San Francisco
Kaiser Foundation Research Institute

Completed

Primary Care-Based Interventions to Reduce Alcohol Use Among HIV Patients

Substance-Related Disorders | Acquired Immunodeficiency Syndrome | Alcoholism | HIV | Alcoholic Intoxication

United States
Bio Products Laboratory

Completed

Pharmacokinetics (PK) and Safety of Subgam-VF in Primary Immunodeficiency Diseases (SCIG03)

Common Variable Immunodeficiency | Primary Immune Deficiency Disorders | X-linked Agammaglobulinaemia | Hyperimmunoglobulin M Syndrome

United States
Stockton University
Nova Southeastern University

Completed

The Impact of Exercise on Stress, Fatigue, and Quality of Life in Individuals With Primary Immunodeficiency Disease

Common Variable Immunodeficiency | Hypergammaglobulinemia | Primary Immune Deficiency Disorder | Specific Antibody Deficiency

United States

Search clinical trials for: Primary Immunodeficiency Diseases

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