Search clinical trials for: Relapsed/refractory after receiving three or more lines of therapy

Total 454812 results

N.N. Blokhin National Medical Research Center of...

Recruiting

Osimertinib for Russian EGFR T790M Mutation-positive NSCLC Patients Who Progressed on or After EGFR TKI Therapy (TRUST)

Non Small Cell Lung Cancer | EGFR Gene Mutation | T790M

Russian Federation
Lei Li

Recruiting

Prognosis of Low-grade Endometrial Stromal Sarcoma

Recurrence | Survival Outcomes | Adjuvant Therapy | Hormone Therapy | Low Grade Endometrial Stromal Sarcoma of Uterus (Diagnosis) | Fertility-sparing Surgery | Fertility Outcomes

China
University of Malaga
Antonia Maria Ruiz Moreno; María Dolores Martínez Colmena; María del Carmen Iniesta... and other collaborators

Not yet recruiting

Laser Therapy for Treatment of Genitourinary Syndrome of Menopause (GSM) in Postmenopausal Women (LASER_2022)

Genitourinary Syndrome of Menopause

Spain
University of Sao Paulo General Hospital

Recruiting

Cost-effectiveness Analysis Between Two Anticoagulation Strategies for Atrial Fibrillation in the Postoperative Period of Coronary Artery Bypass Graft Surgery (TASK-POAF)

Atrial Fibrillation New Onset

Brazil
National Cancer Institute (NCI)

Recruiting

M9241 in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer or Intrahepatic Cholangiocarcinoma

Colorectal Neoplasms | Colorectal Cancer | Cholangiocarcinoma | Bile Duct Cancer | Bile Duct Neoplasms | Metastatic Colorectal Cancer (Mcrc) | Intrahepatic Cholangiocarcinoma (Icc) | Intrahepatic Bile Duct Cancer

United States
Fundacin Biomedica Galicia Sur

Recruiting

Single Antiplatelet Treatment With Ticagrelor or Aspirin After Transcatheter Aortic Valve Implantation (REAC-TAVI2)

Aortic Valve Stenosis | Severe Aortic Valve Stenosis | Transcatheter Aortic Valve Implantation (TAVI) | Transcatheter Aortic Valve Replacement (TAVR)

Spain
NATCO Pharma Ltd.

Recruiting

Study to Evaluate the Safety and Efficacy of Oral NRC-2694-A in Combination With Paclitaxel in Patients With Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma, Who Progressed on or After Immune Checkpoint Inhibitor Therapy

Carcinoma | Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma

United States, India
Stichting European Myeloma Network
Janssen Research & Development, LLC

Recruiting

A Study of Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (DVRd) Followed by Ciltacabtagene Autoleucel Versus Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (DVRd) Followed by Autologous Stem Cell Transplant (ASCT) in Participants With Newly Diagnosed Multiple Myeloma (CARTITUDE-6)

Multiple Myeloma

Netherlands, United States, Spain, Belgium, France, Italy, Germany, Japan, Canada, Australia, Sweden, Israel, United Kingdom, Czechia, Greece, Switzerland, Norway
Intergroupe Francophone de Cancerologie Thoracique

Recruiting

De-escalation Immunotherapy mAintenance Duration Trial for Stage IV Lung Cancer Patients With Disease Control After Chemo-immunotherapy Induction (DIAL)

Metastatic NSCLC

France
Second Affiliated Hospital, School of Medicine,...

Recruiting

Individual Dosing of Levothyroxine After Thyroidectomy

Hypothyroidism | Surgery | Thyroid Neoplasms

China
General University Hospital, Prague

Not yet recruiting

Early Salvage Therapy for Patients With Advanced Features for Biochemical Relapse After Radical Prostatectomy for Localized Prostate Carcinoma In Correlation With Supposed Molecular-genetic Parameters of Higher Aggressiveness (ESTABLISH)

Prostate Cancer
University Medical Center Goettingen

Recruiting

Effect of Antifibrotic Therapy on Regression of Myocardial Fibrosis After Transcatheter Aortic Valve Implantation (TAVI) in Aortic Stenosis Patients With High Fibrotic Burden (Reduce-MFA)

Aortic Stenosis, Severe

Germany
Hospital Universitari Vall d'Hebron Research Institute

Recruiting

Endovascular Embolization of Chronic Subdural Hematomas After Surgery (ENCLOSURE)

Chronic Subdural Hematoma

Spain
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Observational Study to Deeply Phenotype Major Organs in Sickle Cell Disease After Curative Therapies

Mortality in Sickle Cell | Sickle Cell Cardiopulmonary Complications | Sickle Cell Organ Damage | Sickle Cell Life Expectancy and Risk Factors for Early Death | Sickle Cell Lung Disease and Sudden Death

United States
Instituto de Investigación en Oncología Radioterápica...
Instituto de Investigación en Oncología Radioterápica FEOR (IRAD-FEOR)

Recruiting

START-MET HS Prostate Cancer. : SbrT & Androgen Receptor Therapy METastatic HSPC (START-MET)

Prostate Cancer | Stereotactic Body Radiation Therapy

Spain
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Cisplatin, Nab-paclitaxel, Nivolumab With Radiotherapy After Resection of Non-Metastatic Muscle Invasive Bladder Cancer (CNN-BC)

Muscle-Invasive Bladder Carcinoma

Italy
Tanta University

Not yet recruiting

Comparison of 2 Days Versus 5 Days of Octreotide After Endoscopic Therapy in Preventing Early Esophageal Varices Rebleed : A Randomized Controlled Study

Esophageal Varices
Xiamen LP Pharmaceutical Co., Ltd

Recruiting

Buccal Film vs IV Palonosetron for Prevention of CINV in Cancer Patients Receiving MEC

Chemotherapy-induced Nausea and Vomiting

United States
Seoul National University Hospital
Seoul National University Bundang Hospital

Recruiting

Early RRT in AKI After Cardiac Surgery

Acute Kidney Injury

Korea, Republic of
Ottawa Hospital Research Institute

Recruiting

Impact of Hormonal Therapy on Prostate Cancer Recurrence After Radical Prostatectomy

Prostate Cancer

Canada
Mahidol University
Thai AIDs society

Recruiting

Efficacy and Safety of Low-Dose Colchicine on Surrogate Markers of Cardiovascular Events in People Living With HIV Receiving Antiretroviral Therapy

HIV Infections | Inflammatory Markers | Colchicine Adverse Reaction

Thailand
Takeda

Recruiting

A Study of Soticlestat as an Add-on Therapy in Children and Adults With Dravet Syndrome or Lennox-Gastaut Syndrome

Lennox Gastaut Syndrome (LGS) | Dravet Syndrome (DS)

United States, China, Spain, France, Belgium, Australia, Brazil, Canada, Germany, Greece, Hungary, Italy, Japan, Latvia, Netherlands, Poland, Serbia, Mexico, Russian Federation, Ukraine
National Cancer Institute (NCI)

Recruiting

18F-DCFPyL Imaging as a Method to Assess Treatment Response to Stereotactic Body Radiation Therapy

Localized Prostate Cancer

United States
Centre for Addiction and Mental Health

Recruiting

Three-level Model of DBT-informed Care for Youth With and/or at Familial Risk for Bipolar Disorder (DB3) (DB3)

Bipolar Disorder

Canada
T.C. ORDU ÜNİVERSİTESİ

Recruiting

The Effect of Heat Therapy on Shoulder Pain and Physiologic Parameters After Laparoscopic Cholecystectomy

Shoulder Pain | Nursing Caries | Cholecystectomy

Turkey
Sidney Kimmel Comprehensive Cancer Center at Johns...

Recruiting

Intraoperative Radiation Therapy After Stereotactic Body Radiation Therapy and Chemotherapy in Treatment of Pancreatic Adenocarcinoma

Pancreatic Cancer

United States
EDGREM Investimentos
University of Alabama at Birmingham

Recruiting

Evaluation of Ipsilateral Tubal Patency After Conservative Medical or Surgical Treatment. (EENCBE)

Ectopic Pregnancy

Angola
National Institute of Oncology, Hungary

Not yet recruiting

Neoadjuvant Treatment of Breast Cancer

Breast Cancer

Hungary
Medical College of Wisconsin

Recruiting

Maintenance Belantamab Mafodotin (Blenrep®) After B-cell Maturation Antigen-Directed Chimeric Antigen Receptor T-cell Therapy in Patients With Relapsed and/or Refractory Multiple Myeloma (EMBRACE)

Refractory Multiple Myeloma | Relapse Multiple Myeloma

United States
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Immunophenotyping in Metastatic Kidney Cancer Patients Receiving Ablative Therapy

Metastatic Renal Cell Carcinoma | Stage IV Renal Cell Cancer AJCC v8

United States
Novartis Pharmaceuticals

Recruiting

A Multicenter Study of Continued Current Therapy vs Transition to Ofatumumab After Neurofilament (NfL) Elevation (SOSTOS)

Relapsing-Remitting Multiple Sclerosis

Canada, United States
AbbVie

Recruiting

A Study to Assess Real-World Use, Safety, and Effectiveness of Oral Upadacitinib in Adult and Adolescent (>=12 Years Old) Participants With Atopic Dermatitis (AD-VISE)

Atopic Dermatitis

Australia, Austria, Canada, Spain, Switzerland, Taiwan, United Arab Emirates, Poland, Czechia, Greece, Russian Federation, Italy, Israel, Argentina, Hungary, Mexico
Twin Cities Orthopedics

Recruiting

Full Vs Partial Weightbearing During the First Six Weeks of Rehab. After Fibular Collateral Ligament Reconstruction

Knee Injuries

United States
NRG Oncology
National Cancer Institute (NCI)

Recruiting

Two Studies for Patients With Unfavorable Intermediate Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a Higher Gene Risk Score

Prostate Adenocarcinoma

United States, Canada
NRG Oncology
National Cancer Institute (NCI)

Recruiting

Comparing High-Dose Cisplatin Every Three Weeks to Low-Dose Cisplatin Weekly When Combined With Radiation for Patients With Advanced Head and Neck Cancer

Advanced Head and Neck Squamous Cell Carcinoma | Squamous Cell Carcinoma of Unknown Primary | Advanced Hypopharyngeal Squamous Cell Carcinoma | Advanced Laryngeal Squamous Cell Carcinoma | Advanced Oropharyngeal Squamous Cell Carcinoma

United States, Canada
University Hospital Virgen de las Nieves
Hospital Universitario Reina Sofia de Cordoba; Hospitales Universitarios Virgen... and other collaborators

Recruiting

SCAP vs HIFU for Recurrent Prostate Cancer After Radiation Therapy (SALVPROST)

Recurrent Prostate Cancer | Cryotherapy | High Intensity Focused Ultrasounds

Spain, France
Cairo University

Recruiting

Role of Prophylactic Antibiotics in Preventing Pelvic Infection After Surgical Evacuation

Antibiotics Causing Adverse Effects in Therapeutic Use

Egypt
SWOG Cancer Research Network
National Cancer Institute (NCI)

Recruiting

Testing the Use of Chemotherapy After Surgery for High-Risk Pancreatic Neuroendocrine Tumors

Pancreatic Neuroendocrine Tumor | Metastatic Malignant Neoplasm in the Liver | Stage I Pancreatic Neuroendocrine Tumor AJCC v8 | Stage II Pancreatic Neuroendocrine Tumor AJCC v8 | Stage III Pancreatic Neuroendocrine Tumor AJCC v8

United States
Novo Nordisk A/S

Recruiting

ZEUS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Cardiovascular Disease, Chronic Kidney Disease and Inflammation (ZEUS)

Inflammation | Chronic Kidney Disease | Cardiovascular Risk

Korea, Republic of, Italy, United States, Spain, China, Taiwan, Mexico, Netherlands, Latvia, Malaysia, Thailand, Hungary, Australia, Poland, South Africa, India, Canada, Portugal, Romania, United Kingdom, Bulgaria, Germany, Brazil, Sw... and more
VA Office of Research and Development

Recruiting

Consulting After Combat: Interviewing Veterans to Develop a Therapy to Restore Functioning and Reintegration After Moral Injury Events (CAC)

Moral Injury | Functional Impairment

United States
M.D. Anderson Cancer Center

Recruiting

Neurocognitive Outcomes After Whole Brain Radiation Therapy for Hematologic Malignancies

Hematopoietic and Lymphoid Cell Neoplasm | Lymphoma | Leukemia | Plasma Cell Myeloma | Central Nervous System Lymphoma | Secondary Central Nervous System Lymphoma

United States
Sun Yat-sen University
First Affiliated Hospital, Sun Yat-Sen University; Second Affiliated Hospital...

Recruiting

Application of Whole-course Standardized Nutrition Management During Peri-radiotherapy in Patients With Nasopharyngeal Carcinoma After Radiotherapy: a Multicenter Randomized Controlled Clinical Study

Nasopharyngeal Carcinoma | Nutrition Disorders | Radiation Therapy Induced Change

China
OHSU Knight Cancer Institute
Oregon Health and Science University

Recruiting

Standard Verbal Counseling With or Without a Pictorial Educational Tool for the Reduction of Psychological Morbidity in Patients With Stage 0-IIIA Breast Cancer Receiving Radiation Therapy, COPE Study

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Prognostic... and other conditions

United States
Armed Forces Post Graduate Medical Institute (AFPGMI)...

Recruiting

Effectiveness of Combined Anticoagulation and Antithrombotic Therapy vs Antithrombotic Therapy Alone After Lower Extremity Revascularization for Peripheral Arterial Disease

PAD - Peripheral Arterial Disease | Combined Anticoagulation and Antithrombotic Therapy

Pakistan
Maimónides Biomedical Research Institute of Córdoba
FESIA Technology

Recruiting

Study of the Effectiveness of "Fesia Grasp": Functional Electrical Stimulation Device for Upper Limb Rehabilitation After Stroke (PI52021Rehab)

Stroke | Upper Extremity Paresis

Spain
Takeda

Recruiting

A Study of Real Life Treatment for Multiple Myeloma (MM) (LEADER)

Multiple Myeloma

Russian Federation
A2 Biotherapeutics Inc.
Tempus AI

Recruiting

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing (BASECAMP-1)

Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Neoplasms | Ovarian Cancer | NSCLC | Non Small Cell Lung Cancer | Mesothelioma | Mesothelioma, Malignant | Pancreas Cancer | Ovarian Carcinoma | Solid Tumor, Adult | CRC | Mesothelioma; Lung

United States
Novartis Pharmaceuticals

Recruiting

A NIS of Alpelisib in Combination With Fulvestrant in Postmenopausal Women, and Men, With HR+,HER2- , Locally Advanced or Metastatic Breast Cancer With a PIK3CA Mutation, After Disease Progression Following Endocrine Therapy as Monotherapy, in the Real-world Setting

Hormone Receptor Positive HER2 Negative Breast Cancer With a PIK3CA Mutation

Spain, Italy, Austria
Rabin Medical Center

Recruiting

The Effect of Nutritional Formula Supplementation on Linear Growth of Growth Hormone (GH) Treated Prepubertal Children With Idiopathic Short Stature (ISS) After 2 Years From the Beginning of GH-therapy

ISS- Idiopathic Short Stature

Israel
Madrigal Pharmaceuticals, Inc.

Recruiting

A Phase 3 Study to Evaluate Safety and Biomarkers of Resmetirom (MGL-3196) in Patients With Non-alcoholic Fatty Liver Disease (NAFLD), MAESTRO-NAFLD-Open-Label-Extension (MAESTRO-NAFLD-OLE)

Non-Alcoholic Fatty Liver Disease

United States, Puerto Rico

Search clinical trials for: Relapsed/refractory after receiving three or more lines of therapy

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