Search clinical trials for: Repurposed drugs

Total 257783 results

Ohio State University
Patient-Centered Outcomes Research Institute; Northwestern University; Preeclampsia...

Not yet recruiting

Effectiveness of Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy: ASPIRIN TRIAL (ASPIRIN)

Preeclampsia | Gestational Hypertension | Hypertensive Disorders of Pregnancy

United States
The First Affiliated Hospital with Nanjing Medical...

Recruiting

Predicting Ventilator-associated Lower Respiratory Tract Infection Outcomes Using Sequenced-based Early Microbiological Response: A Multi-center Prospective Study

Respiratory Tract Infections | Pneumonia, Ventilator-Associated | Prognosis

China
Fujian Cancer Hospital

Not yet recruiting

Phase II Study of Different Doses of Radiotherapy Combined With Sintilimab in the Treatment of Locally Advanced Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma
AstraZeneca
Daiichi Sankyo Company, Limited 3-5-1 Nihonbashihoncho, Chuo-ku, Tokyo

Not yet recruiting

Phase 3 Study of T-DXd and Rilvegostomig Versus SoC in Advanced HER2-expressing Biliary Tract Cancer (DESTINY-BTC01)

Biliary Tract Cancer

Belgium, Canada, Brazil, Japan, Korea, Republic of, Taiwan, Germany, Austria, Netherlands
Ricardo Alberto Moreno, M.D., Ph.D.

Recruiting

Psychoeducational Group for Depression (PEG-D)

Major Depressive Disorder (MDD

Brazil
Chinese University of Hong Kong

Recruiting

Boiled Tree Nut for Oral Immunotherapy in Food-allergic Children

Food Allergy | Food Allergy in Children

Hong Kong
National Taiwan University

Not yet recruiting

The Gather: Town Gaming Intervention for Depression Management

Gamification
Ain Shams University

Not yet recruiting

Evaluation of Pulpotomy Using Two Different Agents in Mature Anterior Teeth With Pulpitis

Pulpitis
Fujian Cancer Hospital

Not yet recruiting

Short-course Radiotherapy Combined With Sintilimab for Neoadjuvant Treatment of Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma
Beijing Tongren Hospital

Recruiting

GDFT on the Postoperative Outcome in Head and Neck Cancer Surgery

Postoperative Complications

China
Chang Gung Memorial Hospital

Not yet recruiting

Efficacy and Safety of Hydroxychloroquine in the Treatment of Sudden Sensorineural Hearing Loss

Sudden Hearing Loss
Central Hospital, Nancy, France

Recruiting

Heart Analysis in GATED-PET in Patients Having a Gallium-68-DOTATOC PET/CT Exam for Oncology Indication (GATEDOTA)

Cardiac Inflammation

France
Institute of Liver and Biliary Sciences, India

Not yet recruiting

Safety and Adequacy of Trans-jugular Liver Biopsy in Patients With Liver Disease: SAFE-TJLB Study

Liver Cirrhosis

India
Assiut University

Recruiting

Efficacy of Hyaluronic Acid in Prevention of Acute Radiation Proctitis

Acute Radiation Enteritis | Acute Radiation Proctitis

Egypt
Tang-Du Hospital

Recruiting

Study on the Therapeutic Effect of Irinotecan Liposomes in Small Cell Lung Cancer

Small Cell Lung Cancer

China
Grupo Espanol de Trabajo en Enfermedad de Crohn...
Pfizer

Recruiting

An Active Surveillance, Post-Authorization Study to Characterize the Safety of Tofacitinib in Patients With Moderately to Severely Active Ulcerative Colitis in the Real-World Setting Using Data From the United Registries for Clinical Assessment and Research (UR-CARE) in the European Union (EU) (PASS TOFA)

Ulcerative Colitis

Belgium, Bulgaria, Greece, Lithuania
IRCCS San Raffaele
GlaxoSmithKline

Not yet recruiting

Antiviral Long Acting Drugs Landing in People Living With HIV (ALADDIN)

HIV | Antiviral Agents

Italy
University of East Anglia
Clinical Research and Trials Unit (Norfolk & Norwich University Hospital,...

Recruiting

The Role of SGLT2i in Management of Moderate AS

Moderate Aortic Valve Stenosis

United Kingdom
Innovent Biologics (Suzhou) Co. Ltd.

Recruiting

A Study of IBI363 in Subjects With Advanced Malignancies

Advanced Malignancies

China
Kanuni Sultan Suleyman Training and Research Hospital

Not yet recruiting

Evaluation of the Impact of Ejection Fraction on Clinical Outcomes in Patients Undergoing Cardiovascular Surgery

Cardiac Output, Low
Shanghai Chest Hospital

Not yet recruiting

Neoadjuvant Immunochemotherapy for Adenocarcinoma of the Esophagogastric Junction (TRACE)

Esophageal Cancer

China
Chang Gung Memorial Hospital

Not yet recruiting

Novel Augmentation of DAOIB and Antioxidant for Early Dementia

Alzheimer Disease | Mild Cognitive Impairment

Taiwan
L & L biopharma Co., Ltd., Shanghai China
Shanghai East Hospital

Not yet recruiting

A Study to Evaluate LB1410 in Combination With LB4330 in Patients With Advanced or Metastatic Solid Tumors (TRIGGERCD8)

Solid Tumor

China
Central Hospital, Nancy, France

Not yet recruiting

Study of the Indications for Amyloid Positon Emission Tomography (PET) Scans and Their Usefulness for Patients With Suspected Alzheimer's Disease (AD) (TEPAmy)

Alzheimer Disease
Mikko Niemi
University of Helsinki

Recruiting

KF2023#1-Trial: Influence of Statin Intake on Cellular Readouts

Pharmacodynamics

Finland
Pamukkale University

Not yet recruiting

Sympatholytic Effects of High Thoracic Erector Spinae Plane Block: Changes in Optic Nerve Sheath Diameter

Complex Regional Pain Syndromes
Taichung Tzu Chi Hospital

Recruiting

The Efficacy of Music on Perioperative Pain Management

Perioperative Pain Management

Taiwan
Xin-Hua Xu

Recruiting

A Prospective, Open-label, Single-center, Single-arm Phase II Clinical Study of Cadonilimab (AK104) Combined With Monotherapy Chemotherapy in Patients With Advanced Non-small Cell Lung Cancer With Negative Driver Genes and Failed Immunotherapy

Non-small Cell Lung Cancer

China
Peking University People's Hospital

Recruiting

Effects of Chinese Medicine and Lactobacillus in Persistent HPV Infection (ELIMVLHPV)

Human Papilloma Virus Infection

China
Peking University First Hospital
Peking University International Hospital; Tianjin Medical University General...

Not yet recruiting

Dexmedetomidine-Esketamine Combination for Sedation and Analgesia in ICU Patients

Delirium | Dexmedetomidine | Aged | Intensive Care Units | Esketamine | Ventilators, Mechanical

China
King's College Hospital NHS Trust
King's College London

Not yet recruiting

ESCALATion of Medical Therapy Following Multimodality Plaque Evaluation in High-risk Chronic Coronary Syndromes (ESCALATE)

Coronary Artery Disease
Alcon Research

Not yet recruiting

Clinical Performance of Two Frequent Replacement Silicone Hydrogel Multifocal Contact Lenses

Presbyopia

United States
Centre Hospitalier Universitaire de Saint Etienne
Sanofi Pasteur, a Sanofi Company

Recruiting

Analyzes of Nasal Tissue-resident Memory Immune Cells and Peripheral Memory Cells Able to Migrate to Airway Tissues (MUCOVAC) (MUCOVAC)

Healthy Volunteers

France
Shanghai Zhongshan Hospital

Not yet recruiting

Synergistic Effects of PD-1 Antibody and Chemotherapy Followed by Surgery in Limited-metastatic G/GEJ Adenocarcinoma (ROSETTE)

Gastric Cancer | GastroEsophageal Cancer

China
Xianmin Song, MD

Recruiting

Reduced Intensity Conditioning With Thiotepa Combined With Bu/Flu/Ara-C in Allo-HSCT for Relapsed or Refractory Peripheral T-cell Lymphoma.

Peripheral T Cell Lymphoma

China
Hospital de Clinicas de Porto Alegre

Not yet recruiting

The Impact of Geriatric Assessment on the Treatment Plan of Elderly Patients With T2DM

Frail Elderly Syndrome | Frailty | Geriatric Assessment | Type2diabetes

Brazil
National Aeronautics and Space Administration (NASA)

Recruiting

Effect of Sex on Orthostatic Intolerance and Cardiovascular Response During Lunar Descent and Ascent (Lunar OI)

Healthy

United States
Sun Yat-sen University

Not yet recruiting

Neoadjuvant HAIC and PD-1 Plus Adjuvant PD-1 for High-risk Recurrent HCC

Hepatocellular Carcinoma | Beyond Milan Criteria
Shanghai Simnova Biotechnology Co.,Ltd.

Not yet recruiting

F01 in the Treatment of Moderate-to-severe Refractory Systemic Lupus Erythematosus

Lupus Erythematosis

China
Assuta Ashdod Hospital

Not yet recruiting

Oxytocin Effectiveness in First Trimester Dilatation and Curettage - a Double Blind Placebo Controlled Randomized Trial

Missed Abortion
Changhai Hospital
Rui Therapeutics

Not yet recruiting

An Exploratory Clinical Study of Anti-CD19 CAR NK Cell (KN5501) in the Treatment of Relapsed/Refractory Immune Nephropathy

Nephropathy
Ain Shams University

Recruiting

Does Non-Steroidal Anti-inflammatory Drugs Decrease the Quality of Pleurodesis After Mechanical Pleural Abrasion/Pleurectomy for Treatment of Pneumothorax?

Primary and Secondary Spontaneous Pneumothorax

Egypt
Regeneron Pharmaceuticals

Not yet recruiting

A Study to Learn if 27T51, a Mucin-16 (MUC16) Protein Targeting Immune Cell Therapy, Administered Alone or in Combination is Safe and How Well it Works for Adult Participants With Recurrent or Treatment Resistant Ovarian Cancers

Fallopian Tube Cancer | Epithelial Ovarian Cancer | Primary Peritoneal Carcinoma

United States
National Aeronautics and Space Administration (NASA)

Recruiting

Fluid Loading Countermeasures

Healthy

United States
First Affiliated Hospital of Xinjiang Medical University

Not yet recruiting

Efficacy of Local Antibiotic Injection Via a Catheter for Treating Acute Periprosthetic Infections After Knee DAIR Surgery (YES)

Local Antibiotic Injection Catheter Acute Periprosthetic Infections Knee DAIR Randomized Controlled Trial
GT Metabolic Solutions, Inc.

Recruiting

MagDI Canada Study

Obesity | Type 2 Diabetes

Canada
University of California, Davis
Knownwell

Recruiting

CRAVE Study: Comparing Craving Responses and Diet Quality of GLP1 Receptor Agonist Users

Obesity

United States
The First Affiliated Hospital with Nanjing Medical...

Recruiting

NALIRIFOX as Induction Therapy in LAPC

Pancreatic Ductal Adenocarcinoma

China
Le Yu

Recruiting

Ultrasound-guided Modified Transversus Thoracic Muscle Plane Block and Erector Spinal Muscle Plane Block in Heart Valve Replacement Surgery With Median Incision

Anesthesia

China
Universidade Federal Fluminense

Not yet recruiting

Evaluation of Chlorhexidine Gel Associated With Photodynamic Therapy in the Treatment in Diabetic Participants

Diabetes Mellitus, Type 2 | Periodontitis | Periodontitis, Adult

Brazil

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