Search clinical trials for: Single Patient Study

Total 208134 results

AGC Biologics S.p.A.

Completed

Study of NGR-hTNF as Single Agent in Patients Affected by Advanced or Metastatic Malignant Pleural Mesothelioma (NGR010)

Malignant Pleural Mesothelioma

Italy
AGC Biologics S.p.A.

Completed

Study of NGR-hTNF as Single Agent in Patients Affected by Colorectal Cancer (CRC)

Colorectal Cancer (CRC)

Italy
Daiichi Sankyo, Inc.
Integrium

Completed

A Dose Escalation Study of a Combination Antihypertensive Drug in the Treatment of Various Groups of Patients Who do Not Respond to Single Drug Treatment of Their High Blood Pressure (BP CRUSH)

Hypertension

United States
Celgene

Completed

Safety and Efficacy of CC-486 in Previously Treated Patients With Locally Advanced or Metastatic Nasopharyngeal Carcinoma

Nasopharyngeal Neoplasms

Canada, United States, Taiwan, France, Spain, Greece, Italy, Singapore, Tunisia
Medical University of South Carolina
American Heart Association

Completed

Study of Effects of Sildenafil on Patients With Fontan Heart Circulation

Single Ventricle Heart Disease After Fontan Surgery

United States
Merck Sharp & Dohme LLC

Approved for marketing

Single Patient Treatment of Posaconazole in Invasive Fungal Infections (Study P05113)

Mycoses
Synthetic Biologics Inc.

Completed

A Single-Dose, Open-Label, Study to Evaluate the Sustainability of the Effects of SYN-010 in Patients With IBS-C

Irritable Bowel Syndrome With Constipation (IBS-C)

United States
Arthrogen
Centre for Human Drug Research (CHDR)

Unknown

A Single Dose Clinical Trial to Study the Safety of ART-I02 in Patients With Arthritis

Arthritis, Rheumatoid | Osteo Arthritis

Netherlands
Astellas Pharma Inc

Completed

Single and Multiple Dosing Study in Hemodialysis Patients With Hyperphosphatemia in Japan

Chronic Kidney Disease | Hyperphosphatemia Undergoing Hemodialysis

Japan
Astellas Pharma Inc
Astellas Pharma Global Development, Inc.

Completed

An Open-label Phase I Study of Orally Available Novel Small-molecule Fibroblast Growth Factor Receptors (FGFR) 1,2,3 and 4 Inhibitor, ASP5878 at Single and Multiple Doses in Patients With Solid Tumors

Solid Tumors

United States, Japan, Korea, Republic of, Taiwan
Samsung Medical Center

Terminated

Phase II, Single-arm Study of AZD1775 Monotherapy in Relapsed Small Cell Lung Cancer Patients With MYC Family Amplification or CDKN2A Mutation Combined With TP53 Mutation

Small Cell Lung Cancer

Korea, Republic of
Universitair Ziekenhuis Brussel

Unknown

Single-center Prospective Cumulus Cell Test Study in rFSH Patients

Infertility

Belgium
Hoffmann-La Roche

Completed

An Observational Study of Avastin (Bevacizumab) in Combination With Chemotherapy as First-Line Treatment in Patients With Advanced Ovarian Cancer (OSCAR 1)

Ovarian Cancer

United Kingdom
Biocad

Unknown

A Multicenter Open-Label Single-Arm Multi-Cohort Phase I Study of BCD-100 in Patients With Advanced Solid Tumors

Melanoma | Renal Cell Carcinoma | Lung Cancer

Russian Federation
The Lymphoma Academic Research Organisation
Novartis

Completed

A Phase II Study of Oral JAK1/JAK2 Inhibitor INC424 in Adult Patients With Relapsed/Refractory Classical Hodgkin's Lymphoma (HIJAK)

Hodgkin's Lymphoma

France, Belgium
Abramson Cancer Center of the University of Pennsylvania

Completed

Redosing With CP-870, 893 in Patients With Clinical Benefit After a Single Infusion From A Phase I, Open-Label, Dose-Escalation Study of CP-870,893 in Patients With Solid Tumors

Solid Tumors

United States
National Hepatology & Tropical Medicine Research...

Unknown

Terlipressin Alone Versus the Standard Therapy With Catecholamines for Hepatic Patients With Septic Shock- Prospective Single Center Randomized Controlled Study.

Resolution of Septic Shock With Terlipressin

Egypt
Plexxikon

Terminated

Phase 1 Study of PLX7486 as Single Agent in Patients With Advanced Solid Tumors

Solid Tumor | Tenosynovial Giant Cell Tumor | Tumors of Any Histology With Activating Trk (NTRK) Point or NTRK Fusion Mutations

United States
Yonsei University

Unknown

An Open Label, Single Arm, Multicenter Phase II Study of BYL719 in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of Head and Neck Who Failed to Respond to Platinum-based Therapy.

Recurrent or Metastatic Squamous Cell Carcinoma of Head and Neck

Korea, Republic of
AstraZeneca

Completed

Single Dose Study to Assess Efficacy, Safety and Tolerability of LAS100977 in Asthmatic Patients.

Asthma

Germany, United Kingdom
Washington University School of Medicine

Completed

The Effects of Ambrisentan on Exercise Capacity in Fontan Patients

Single Ventricle Fontan Palliation

United States
Rothman Institute Orthopaedics

Unknown

A Comparative Study to Assess the Prevention of Surgical Site Infection (SSI's) in Revision Total Joint Arthroplasty Patients Treated With Single-Use Negative Pressure Wound Therapy (PICO™) or Standard Care Dressings (AQUACEL® Ag SURGICAL Dressing)

Surgical Wound Infection

United States
Meril Life Sciences Pvt. Ltd.
Lifecare Institute of Medical Sciences and Research Ahmedabad Gujarat India

Completed

Study Safety and Performance of the Biomime Stent in Patients With Single, De Novo, Non-Complex Coronary Lesions (meriT-1)

Coronary Artery Disease

India
AEterna Zentaris

Completed

Placebo-Controlled Study of Perifosine + Single Agent Chemotherapy for Metastatic Cancer Patients

Colon Cancer

United States
Novartis Pharmaceuticals

Completed

Phase II Efficacy Study Looking at a Single-dose of One of Three Dose Levels of AIN457 in Patients With Chronic Plaque-type Psoriasis

Chronic Plaque Psoriasis

United States
Novartis Pharmaceuticals

Completed

An Open Label Multi-center Extension Study to Evaluate Long-term Safety/ Tolerability of Dovitinib in Patients With Solid Tumors Who Continue to Receive Treatment With Dovitinib (TKI258) in Novartis-sponsored Single Agent Dovitinib Studies Which Fulfilled the Requirements for the Primary Objective

Solid Tumors

Austria, Belgium, United States, Italy, Denmark, Spain, Japan
Aspireo Pharmaceuticals Limited

Completed

Single Dose Pharmacology Study of DG3173 and Octreotide in Acromegalic Patients.

Acromegaly
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Stage I-IIIB Non-Small Cell Lung Cancer After Completion of Radiation Therapy Alone or Combined Radiation Therapy and Chemotherapy

Lung Cancer

United States
Riyadh Colleges of Dentistry and Pharmacy

Unknown

Periodontitis and Adverse Pregnancy Outcomes in Metabolic Syndrome Patients- Interventional Study

Periodontitis | Premature Birth | Metabolic Syndrome | Pregnancy Complications | Adverse Pregnancy Outcomes | Low Birth Weight Baby

Saudi Arabia
Sanofi

Completed

Study of Capecitabine and Cyclophosphamide Administered as a Single Pill in Patients With Advanced Breast Cancer (METRO-ABC)

Breast Cancer Metastatic

India
University of California, San Francisco
North American Gamma Knife Consortium

Terminated

A Single Arm Study of Neurocognitive Outcomes in Patients With Brain Metastases Managed With Stereotactic Radiosurgery (SRS)

Brain Metastases

United States
NYU Langone Health

Terminated

Single Center, Open Label, Study of Preparation H on Erythema in Relapsing MS Patients Treated With PLEGRIDY

Multiple Sclerosis

United States
Samsung Medical Center

Completed

A Single Arm, Phase II Study of Simvastatin Plus XELOX and Bevacizumab as First-line Chemotherapy in Metastatic Colorectal Cancer Patients

Colorectal Cancer

Korea, Republic of
Hebei Medical University Fourth Hospital

Unknown

Prospective, Multicenter, Observational Study of Apatinib Single or Combined Capecitabine for Treatment of Patients With Metastatic Her-2 Negative Breast Cancer

Breast Cancer Metastatic

China
GlaxoSmithKline

Completed

Patient Preference Study of Fluticasone Furoate and Mometasone Furoate Nasal Sprays

Rhinitis, Allergic, Perennial and Seasonal

Argentina, Russian Federation, Korea, Republic of, Australia
Mundipharma Korea Ltd

Completed

A Study to Evaluate Efficacy and Safety of Oxycodone/Naloxone Compared to OxyContin in Korean Cancer Patients (TOP)

Cancer

Korea, Republic of
Seoul National University Hospital

Unknown

A Biomarker-driven, Open Label, Single Arm, Multicentre Phase II Study of Abemaciclib in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma Who Failed to Platinum-based Therapy

Head and Neck Neoplasms | HNSCC

Korea, Republic of
Bayer

Completed

A Single-blind Pilot Study to Investigate Safety and Tolerability of the Chymase Inhibitor BAY1142524 in Clinically Stable Patients With Left-ventricular Dysfunction (CHIARA MIA 1)

Heart Failure

Germany, Denmark, Italy
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Immunoscintigraphy Using Radiolabeled Monoclonal Antibody in Finding Tumor Cells in Patients With Colorectal Cancer

Colorectal Cancer

United States
Bristol-Myers Squibb

Terminated

Single Ascending Dose and Multiple Ascending Dose Study in Healthy Participants and Proof of Mechanism Study in Patients With Ulcerative Colitis

Healthy Volunteers | Ulcerative Colitis

Australia, Georgia, Moldova, Republic of
Hoffmann-La Roche

Completed

A Study of Subcutaneous Versus Intravenous MabThera/Rituxan (Rituximab) in Combination With CHOP Chemotherapy in Patients With Previously Untreated CD20-Positive Diffuse Large B-Cell Lymphoma

Lymphoma, Large B-Cell, Diffuse

Italy, Belgium, Canada, Finland, Ireland, Netherlands, Peru, Spain, United Kingdom, Venezuela, Russian Federation, Brazil, France, Poland, Israel, South Africa, Thailand, Bulgaria, Colombia, Greece, Turkey, Argentina, Saudi Arabia, Uk... and more
GlaxoSmithKline

Completed

Study Of Single And Ten Day Repeat Atopical Applications Of GW842470X Cream On The Skin Of Patients With Atopic Dermatitis

Dermatitis, Atopic

Germany
Memorial Sloan Kettering Cancer Center
Weizmann Institute of Science; Cold Spring Harbor Laboratory

Completed

Two Stage Study Of Single Dose PEGPH20 And Cetuximab In Patients With Pancreatic Adenocarcinoma Prior To Surgical Resection

Pancreatic Cancer

United States
Centre Hospitalier Universitaire Dijon

Completed

Extubation of Patients on ECLS is Associated With a Reduction in Complications Related to Mechanical Ventilation: Retrospective Single-centre Study (EXTUB ECLS)

Extra-Corporeal Life Support

France
Pfizer

Completed

A Study to Assess the Safety, Tolerability and Pharmacokinetics of NXL104 Alone and in Combination With Ceftazidime Administered as Single and Repeated Intravenous Doses in Healthy Japanese Subjects

Healthy Male and Female Japanese Volunteers

United States
Hoffmann-La Roche

Completed

A Study of Re-Treatment With MabThera (Rituximab) in Patients With Rheumatoid Arthritis Who Have Had an Inadequate Response to a Single Anti-TNF Inhibitor.

Rheumatoid Arthritis

Germany
GlaxoSmithKline

Completed

A Study to Investigate the Effect of Inhaling Single Doses of Different Formulations of GW642444M in Asthmatic Patients

Pulmonary Disease, Chronic Obstructive

Australia, New Zealand
GlaxoSmithKline

Completed

A Study To Investigate The Effect Of Inhaling A Single Dose Of GW642444M In Asthmatic Patients

Pulmonary Disease, Chronic Obstructive

United Kingdom
GlaxoSmithKline

Completed

Single Dose GW685698X Magnesium Stearate Study In Asthmatic Patients.

Asthma

New Zealand
JIANG Zhi-Wei

Completed

Robotic Resection for Patients With Gastric Gastrointestinal Stromal Tumors: a Single-center Study

Gastrointestinal Stromal Tumor of Stomach

China

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