Search clinical trials for: Tuberculosis

Total 1558 results

Kilimanjaro Clinical Research Institute
European and Developing Countries Clinical Trials Partnership (EDCTP)

Completed

Evaluation of Pharmacokinetics and Safety Tolerability of Higher Doses of Rifampic (HighRif C)

Clinical Trial

Tanzania
Institute of Tropical Medicine, Belgium
Damien Foundation

Active, not recruiting

Novel Triple-dose Tuberculosis Retreatment Regimen (Tri-Do-Re)

Tuberculosis | Pulmonary Tuberculosis | Multidrug-resistant Tuberculosis | Resistance to Tuberculostatic Drugs

Niger
Yale University
National Institute of Mental Health (NIMH); New York University; Fogarty International... and other collaborators

Completed

Interrupting HIV and TB Stigma in the Household in Uganda

Tuberculosis | Hiv | Social Behavior | Stigmatization | Stigma, Social

Uganda
Hospital Universitario 12 de Octubre
Institut National de la Santé Et de la Recherche Médicale, France; University... and other collaborators

Active, not recruiting

Empirical Treatment Against Cytomegalovirus and Tuberculosis in HIV-infected Infants With Severe Pneumonia (EMPIRICAL)

Pneumonia | HIV/AIDS | Tuberculosis | Cytomegalovirus Infections

Zimbabwe, France, Côte D'Ivoire, Italy, Malawi, Mozambique, Netherlands, Spain, Uganda, United Kingdom, Zambia
Medecins Sans Frontieres, Spain
Ministry of Health, Guinea-Bissau; Institute of Tropical Medicine, University... and other collaborators

Completed

Evaluation of Xpert MTB/RIF Ultra in Stools and Urine to Improve Tuberculosis Diagnosis in Children

Tuberculosis | Pediatric Infectious Disease

Guinea-Bissau, South Sudan
Fahad Javed Awan

Completed

Steroids vs Placebo in Treatment of Tuberculous Lymphadenitis

Tuberculous Lymphadenitis, Cervical

Pakistan
Chengdu CoenBiotech Co., Ltd
Beijing Friendship Hospital; Beijing Chest Hospital, Capital Medical University

Completed

Phase I Clinical Trial to Evaluate the Safety of Recombinant Mycobacterium Tuberculosis Fusion Protein (EEC) in Healthy Adults Aged 18-65 and Patients With Pulmonary Tuberculosis

Tuberculosis

China
SPP Pharmaclon Ltd.
North-Western State Medical University named after I.I.Mechnikov

Completed

Study of Interferon-Gamma in the Complex Treatment of Patients Infected With HIV and Tuberculosis (MSPB_TB)

RNA Virus Infections | Lentivirus Infections | Tuberculosis, Pulmonary | Human Immunodeficiency Virus | HIV Coinfection | Aids/Hiv Problem

Russian Federation
University of California, San Francisco
London School of Hygiene and Tropical Medicine; MRC/UVRI and LSHTM Uganda Research... and other collaborators

Completed

Adjunctive Linezolid for the Treatment of Tuberculous Meningitis (ALTER)

Tuberculosis, Meningeal

Uganda
Foundation for Innovative New Diagnostics, Switzerland

Active, not recruiting

Evaluation of the Truenat™MTB Plus/COVID-19 Test for TB (Tuberculosis) and COVID-19 (SARS-CoV2) (Truenat COMBO)

COVID-19 | TB

Uganda
Foundation for Innovative New Diagnostics, Switzerland
Ludwig-Maximilians - University of Munich; Ifakara Health Institute; Centro de... and other collaborators

Active, not recruiting

TB-CAPT CORE Truenat Trial

Tuberculosis | Diagnoses Disease

Tanzania, Mozambique
Kaiser Permanente

Active, not recruiting

Brief Educational Video for Patients Prescribed LTBI Treatment

Latent Tuberculosis

United States
Johns Hopkins University
Cystic Fibrosis Foundation

Completed

Bacille Calmette-Guerin (BCG) Vaccine for Immune Protection Against Infections

Cystic Fibrosis | Bronchiectasis Adult | Non-Tuberculous Mycobacteria

United States
Vertex Pharmaceuticals Incorporated

Completed

Study Evaluating the Long-term Safety and Efficacy of VX-445 Combination Therapy

Cystic Fibrosis

United States, Spain, Ireland, Belgium, Netherlands, United Kingdom, Australia, France, Denmark, Germany, Italy, Canada
Medecins Sans Frontieres, Spain

Completed

Evaluation of Point-of-care Ultrasound in Children From 6 Months to 15 Years With Presumptive Tuberculosis

Tuberculosis

Guinea-Bissau, South Sudan
University of California, San Francisco
National Institute of Allergy and Infectious Diseases (NIAID); Makerere University and other collaborators

Completed

Simplified Isoniazid Preventive Therapy Strategy to Reduce TB Burden (SEARCH-IPT)

HIV/AIDS | Tuberculosis

Uganda
Shanghai Jiatan Pharmatech Co., Ltd

Enrolling by invitation

Sudapyridine (WX-081) in RR/MDR/XDR-tuberculosis Patients (WISH)

Rifampicin-resistant Tuberculosis

China
Otsuka Pharmaceutical Development & Commercialization...
Bill and Melinda Gates Foundation

Active, not recruiting

Safety and Efficacy Evaluation of 4-month Regimen of OPC-167832, Delamanid and Bedaquiline in Participants With Drug-Susceptible Pulmonary TB

Pulmonary TB

South Africa
Fred Hutchinson Cancer Center
Merck Sharp & Dohme LLC

Completed

Phase I Open Label BCG Clinical Trial Assessing TB Drugs and Vaccines

Tuberculosis

United States
University Hospital, Linkoeping
Linkoeping University

Suspended

Drug Exposure and Safety of a Shorter Tuberculosis Treatment Based on High-Dose Rifampicin and Pyrazinamide (HIGHSHORT-RP)

Tuberculosis, Pulmonary

Sweden
Tuberculosis Research Centre, India
King George's Medical University, Lucknow; Mahavir Hospital and Research Centre... and other collaborators

Active, not recruiting

Four Months Moxifloxacin Containing Daily Regimen Study Among New Pulmonary Tuberculosis Patients

Tuberculosis, Pulmonary

India
Tuberculosis Research Centre, India
International Union Against Tuberculosis and Lung Diseases; Sarvodaya Charitable... and other collaborators

Active, not recruiting

Modified BPaL Regimen for Managing Pre-XDR TB and MDR (TI/NR) TB in India (mBPaL)

Pre-Extensively Drug-Resistant Pulmonary TB | Treatment Intolerant Multidrug-Resistant Pulmonary TB | Non-responsive Multidrug-Resistant Pulmonary TB

India
Johns Hopkins University

Completed

Clinical Practice Guidelines Versus Decision-support for Latent Tuberculosis Infection (LTBI) Management

Latent Tuberculosis

United States
United Therapeutics

Completed

FREEDOM - M: Oral Treprostinil as Monotherapy for the Treatment of Pulmonary Arterial Hypertension (PAH)

Pulmonary Hypertension

United States, China, Israel, Belgium, Canada, France, India, Mexico, Austria, Italy, Netherlands, Poland, Puerto Rico
University of Oxford
Wellcome Trust; National Institute for Health Research, United Kingdom; University...

Active, not recruiting

Investigating Immune Responses to Aerosol BCG Challenge in Healthy UK Adults

Tuberculosis

United Kingdom
Tuberculosis Research Centre, India
London School of Hygiene and Tropical Medicine; Queen Mary University of London and other collaborators

Active, not recruiting

The Impact of Malnutrition on Immune Responses to Tuberculosis (TBMAM)

Tuberculosis | Malnutrition, Child

India
National Institute of Allergy and Infectious Diseases...

Terminated

Pretomanid in Adults With Hepatic Impairment

Tuberculosis

United States
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Active, not recruiting

Haploidentical Bone Marrow Transplantation in Sickle Cell Patients (BMTCTN1507)

Sickle Cell Disease

United States
National Taiwan University Hospital

Completed

Risk of SDRs Under 3HP and 1HP Regimen for LTBI

Latent Tuberculosis Infection

Taiwan
Vertex Pharmaceuticals Incorporated

Completed

A Study of VX-121 Combination Therapy in Participants With Cystic Fibrosis (CF) Who Are Homozygous for F508del, Heterozygous for F508del and a Gating (F/G) or Residual Function (F/RF) Mutation, or Have At Least 1 Other Triple Combination Responsive (TCR) CFTR Mutation and No F508del Mutation

Cystic Fibrosis

United States, United Kingdom, Belgium, Netherlands, France, Denmark, Israel, New Zealand, Australia, Ireland, Sweden, Canada, Germany, Poland, Switzerland, Italy, Austria, Hungary, Greece, Norway
Vertex Pharmaceuticals Incorporated

Active, not recruiting

A Study Evaluating the Long-term Safety and Efficacy of VX-121 Combination Therapy

Cystic Fibrosis

United States, Spain, United Kingdom, Belgium, Netherlands, Denmark, Israel, New Zealand, France, Australia, Ireland, Germany, Sweden, Canada, Czechia, Switzerland, Portugal, Italy, Austria, Hungary, Norway, Poland, Greece
Tuberculosis Research Centre, India
All India Institute of Medical Sciences, Bhubaneswar; Institute of Child Health... and other collaborators

Suspended

BCG Revaccination in Children and Adolescents (BRiC)

Tuberculosis | Tuberculosis Infection

India
Huashan Hospital

Active, not recruiting

Subclinical TB With Innovative Modified Short-course Regimens (SWIFT)

Tuberculosis

China
Sema Aytaç, PhD

Completed

Effect of Breathing Exercise on Fatigue in Patients With Pulmonary Tuberculosis

Fatigue | Tuberculosis, Pulmonary

Turkey
Research Center Borstel
Ludwig-Maximilians - University of Munich

Terminated

PredictEndTB Signature for Individualizing Treatment in Multidrug-Resistant Tuberculosis

Bacterial Infections | Tuberculosis, Pulmonary | Tuberculosis, Multidrug-Resistant | Mycobacterial Infection

Germany, Moldova, Republic of, Romania, Ukraine
Obafemi Awolowo University Teaching Hospital
University Hospital Birmingham NHS Foundation Trust; Cures Within Reach

Completed

Treating Tuberculosis With the Lipid Lowering Drug Atorvastatin in Nigeria(ATORvastatin in Pulmonary TUBerculosis) (ATORTUB)

Tuberculosis | Tuberculosis, Pulmonary

United Kingdom, Nigeria
University of Oklahoma

Completed

Screening Strategy for Early Diagnosis of Silicosis in At-Risk Populations in Oklahoma

Silicosis | Pneumoconiosis; Silica

United States
Allama Iqbal Open University Islamabad

Completed

Prokinetic Effect of Selected Nutraceuticals

Pulmonary Tuberculosis | Gastro-Intestinal Disorder

Pakistan
Imperial College Healthcare NHS Trust
Barts & The London NHS Trust; Royal Free Hospital NHS Foundation Trust; University... and other collaborators

Active, not recruiting

TB PCR in BAL and EBUS-TBNA (TRiBE)

Tuberculosis

United Kingdom
Pharmtechnology LLC
Altasciences Company Inc.

Completed

Single Dose Crossover Comparative Bioavailability Study of Two Formulations of Fluconazole 200 mg in Healthy Adult Subjects Under Fasting Conditions

Bioequivalence

Canada
University of California, San Francisco
Johns Hopkins University; National Heart, Lung, and Blood Institute (NHLBI); Makerere... and other collaborators

Active, not recruiting

TB Screening Improves Preventive Therapy Uptake (TB SCRIPT)

HIV | Latent Tuberculosis | Tuberculosis | Tuberculosis Prevention

Uganda
Tuberculosis Research Centre, India
National Institute of Epidemiology

Completed

Characterization and Durability of COVID-19 Vaccine Induced Immune Responses in Healthcare/Frontline Workers

Covid19

India
Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.

Suspended

A Phase Ⅱ Clinical Trial of the Recombinant Mycobacterium Tuberculosis Vaccine Freeze-dried (AEC/BC02)

Tuberculosis

China
Michael Hoelscher
European and Developing Countries Clinical Trials Partnership (EDCTP)

Active, not recruiting

Early Risk Assessment in Household Contacts (≥10 Years) of TB Patients by New Diagnostic Tests in 3 African Countries (ERASE-TB)

Tuberculosis

Tanzania, Mozambique, Zimbabwe
Foundation for Innovative New Diagnostics, Switzerland
Ludwig-Maximilians - University of Munich; Heidelberg University; Swiss Tropical... and other collaborators

Active, not recruiting

TB-CAPT MTB/XDR Study

Tuberculosis | Diagnoses Disease | Resistance Bacterial

South Africa
Ludek Stehlik
University Hospital Olomouc; University Hospital, Motol; Ministry of Health,...

Suspended

Biodegradable Stents in the Management of Stenoses of the Large Airways

Tracheal Stenosis

Czechia
BioVersys AG
TASK Applied Science

Completed

Pharmacokinetics of Ethionamide and Ethionamide Sulfoxide in Patients Established on Treatment for Tuberculosis.

Tuberculosis, Pulmonary

South Africa
University of California, San Francisco
University of Colorado, Denver; National Heart, Lung, and Blood Institute (NHLBI) and other collaborators

Active, not recruiting

Options for Delivering Isoniazid-Rifapentine (3HP) for TB Prevention (3HP Options Implementation Trial)

HIV/AIDS | Latent Tuberculosis | Tuberculosis

Uganda
Foundation for Innovative New Diagnostics, Switzerland

Completed

Evaluation of Centralised TB Assay Solutions

Tuberculosis | Drug-resistant Tuberculosis

Georgia, Germany, India, Moldova, Republic of, South Africa
University of Oxford
University of Birmingham

Completed

Aerosol BCG Challenge Trial in Healthy UK Adults

Tuberculosis

United Kingdom

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