Search clinical trials for: enveloped virus-like particle (eVLP)

Total 402 results

Yonsei University

Completed

Supplementation of Dual Probiotic Strains Reduced Fasting Triglyceride and Enhanced Apolipoprotein A-V Levels

Hypertriglyceridemia

Korea, Republic of
Novavax
Department of Health and Human Services

Completed

A/H5N1 Virus-Like Particle Antigen Dose Ranging Study With Adjuvant 1

Influenza (Pandemic)

United States
Novavax
Department of Health and Human Services

Completed

A/H5N1 Virus-Like Particle Antigen Dose Ranging Study With Adjuvant 2

Influenza (Pandemic)

United States
University of Nottingham
Nottingham University Hospitals NHS Trust; University Hospitals, Leicester

Completed

Small Particle Steroids in Refractory Asthma (SPIRA)

Asthma

United Kingdom
Pfizer

Withdrawn

A Pharmacokinetic Study of Three Different Particle Sizes of PH-797804

Healthy
Mannkind Corporation

Completed

A Trial to Determine How Long Insulin and FDKP (the Molecule That Forms Technosphere Particles) Stays in the Lungs of Healthy Individuals After Inhalation of Technosphere® Insulin (TI) Powder Using Bronchoalveolar Lavage (BAL)

Healthy Subjects

United States
David Diaz-Sanchez
Environmental Protection Agency (EPA)

Completed

Physiological Changes in Adults With Metabolic Syndrome Exposed to Ultrafine Air Particles (XCON)

Metabolic Syndrome

United States
Hadassah Medical Organization

Completed

Efficacy of Sinus Floor Augmentation Using Large or Small Bovine Bone Mineral.

Sinus Graft

Israel
Pfizer

Completed

A Study In Healthy Volunteers To Estimate The Effect Of The Active Ingredient Particle Size And Percentage Of The Excipients Used To Formulate The Capsules In The Dissolution Rate Of The Formulations In The Gastrointestinal Tract

Healthy

United States
Hannover Medical School
Fraunhofer-Institute of Toxicology and Experimental Medicine

Unknown

Experimental Exposure to Air Pollutants and Sympathetic Nerve Activity in Human Subjects (Particles)

Cardiovascular Morbidity

Germany
Novavax

Completed

Evaluate the Safety and Immunogenicity of a Seasonal Influenza Virus-Like Particle (VLP) Vaccine in Older Adults

Influenza

United States
Novavax

Completed

Trial to Evaluate Safety and Immunogenicity of Trivalent Seasonal Influenza Virus-Like Particle (VLP) Vaccine (Recombinant)

Seasonal Influenza

United States
Novavax
Department of Health and Human Services

Completed

A Study to Evaluate the Immune Response and Safety of a Seasonal Virus-Like Particle Influenza Vaccine in Healthy Young Adults

Influenza

Australia
Asan Medical Center
Seoul National University Hospital

Completed

Early Clinical Evaluation of the Pharmacokinetics and Mechanism Based Pharmacodynamics of Haloperidol Using Positron Emission Tomography in Healthy Volunteers

Healthy

Korea, Republic of
Heidelberg University
Merck KGaA, Darmstadt, Germany; University Hospital Heidelberg; Dept. of Radiation...

Unknown

Adenoid Cystic Carcinoma, Erbitux, and Particle Therapy (ACCEPT)

Adenoid Cystic Carcinoma

Germany
Shanghai University of Traditional Chinese Medicine

Unknown

Study on Single-nucleotide-polymorphism in Idiopathic Membranous Nephropathy

Idiopathic Membranous Nephropathy

China
University of Edinburgh
British Heart Foundation; Translational Medicine Research Collaboration

Completed

Tracking Inflammatory Cells Using Superparamagnetic Particles of Iron Oxide (SPIO) and Magnetic Resonance Imaging (MRI)

Healthy

United Kingdom
Yale University
Agennix

Completed

Phase I Study of the Combination of Satraplatin and Abraxane in Advanced Cancers

Advanced Cancers

United States
Tel-Aviv Sourasky Medical Center

Unknown

Biological Monitoring of Nano Sized Particles in the Airways of Asthmatic Children (EHF)

Asthma

Israel
Research in Real-Life Ltd
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Qvar Therapy in Smoking Asthmatics

Smoking | Asthma
Research in Real-Life Ltd
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Qvar Versus Clenil, a General Practice Research Database Study

Asthma

United Kingdom
M.D. Anderson Cancer Center

Terminated

A Validation Study of MR Lymphangiography Using SPIO, a New Lymphotropic Superparamagnetic Nanoparticle Contrast

Prostate Cancer | Bladder Cancer | Genitourinary Cancer

United States
University Health Network, Toronto
Eli Lilly and Company

Completed

Exenatide (Byetta ®) Regulation of Intestinal and Hepatic Lipoprotein Particle Production in Humans

Hyperlipidemia

Canada
Rockefeller University

Completed

The Effect of Vitamin D Repletion on Small Low Density Lipoprotein (LDL) Particle Number in Subjects at Elevated Cardiovascular Risk

Atherosclerosis

United States
Tel-Aviv Sourasky Medical Center

Unknown

The Differential Pattern of Deposition of Nano Particles in the Airways of Exposed Workers (Nanoexposure)

Inadequate or Impaired Respiratory Function
Novavax
Instituto Mexicano del Seguro Social

Completed

Safety and Immunogenicity of an A (H1N1) 2009 Influenza Virus-like Particle (VLP) Vaccine

Seasonal Influenza

Mexico
Novavax

Completed

Safety Study of Respiratory Syncytial Virus (RSV)-Fusion (F) Protein Particle Vaccine

Respiratory Syncytial Virus Infections

United States
University of Aarhus
Aarhus University Hospital; University of Copenhagen

Completed

HIPWOODS - Health Effects Related to Exposure to Particle Pollution From Woodburning Stoves (HIPWOODS)

Systemic Inflammation | Airway Inflammation

Denmark
University of Aarhus
CMP Therapeutics Ltd

Completed

Immunological Effects From Intranasal Chitin Micro-Particles (INCA)

Healthy

Denmark
Genta Incorporated

Unknown

Abraxane and Temodar Plus Genasense in Advanced Melanoma

Melanoma

United States
Environmental Protection Agency (EPA)

Completed

Cardioprotective Effects of Omega-3 Fatty Acids Supplementation in Healthy Older Subjects Exposed to Air Pollution Particles

Healthy

United States
University of Ioannina

Completed

Comparison of Simvastatin Versus Simvastatin/Ezetimibe on Small Dense Low -Density Lipoprotein (LDL)

Hypercholesterolemia

Greece
University of California, San Francisco

Completed

Dose-dependent Effects of Second-hand Smoke on Vascular Function

Cardiovascular Disease

United States
AstraZeneca

Completed

A Bioavailability Study Comparing 3 Different AZD1981 Tablets

Healthy

Sweden
Mayo Clinic
National Cancer Institute (NCI)

Completed

ABI-007 (Nab-Paclitaxel) and Gemcitabine in Treating Women With Metastatic Breast Cancer

Breast Cancer

United States
Hospital Clinic of Barcelona
Fundacion Clinic per a la Recerca Biomédica; Fundació Institut de Recerca de... and other collaborators

Unknown

Typical Versus Atypical Antipsychotics; Occupation of Striatal Receptors and the Appearance of Extrapyramidal Symptomatology, in Healthy Volunteers (APSEP)

Healthy | Pharmacogenetics

Spain
University Hospital, Antwerp
AstraZeneca

Completed

Assess Particle Deposition and Acute Effects of Symbicort® Forte Turbohaler®) in COPD Patients.

Chronic Obstructive Pulmonary Disease

Belgium
Medicago

Completed

Safety Study of a Plant-based H5 Virus-Like Particles (VLP) Vaccine in Healthy Adults

RNA Virus Infections | Virus Diseases | Respiratory Tract Infections | Respiratory Tract Diseases

Canada
GlaxoSmithKline

Completed

A Study to Examine the Effect of Particle Size on Bioequivalence and Bioavailability

Rheumatoid Arthritis | Atherosclerosis | Chronic Obstructive Pulmonary Disease (COPD)

United States
Chonbuk National University Hospital

Completed

Evaluation of Negative Symptoms and Cognitive Function After Administration of Antipsychotics in Healthy Volunteer

Normal Volunteers

Korea, Republic of
University of Helsinki
Samfundet Folkhälsan; Sigrid Jusélius Foundation; Fazer

Completed

Rye Bread Trial; Antioxidative and Cholesterol Lowering Effects (Rye-2008)

Hypercholesterol

Finland
Dr. Reddy's Laboratories Limited

Completed

Bioequivalence Study of Dr. Reddy's Divalproex Sodium Coated Particles in Capsules, 125 mg, Under Fed Condition

Healthy

India
Hadassah Medical Organization

Unknown

Antibacterial Properties of Silicon Incorporated With Quaternary Ammonium Polyethylenimine Nanoparticles

Carcinoma of Head and Neck
Fraunhofer-Institute of Toxicology and Experimental...
German Research Foundation

Completed

Influence of Diesel Exhaust Particles (DEP) With and Without Organic Compounds on the Allergic Inflammation in Asthmatic Subjects

Asthma

Germany
PowderMed

Completed

Safety Study of HBV DNA Vaccine to Treat Patients With Chronic Hepatitis B Infection

Chronic Hepatitis B

Thailand, Hong Kong, Singapore, Taiwan
PowderMed

Completed

A Safety Study to Assess a DNA Vaccine Administered by Particle Mediated Delivery to the Skin in Healthy Subjects

HSV-2

United States
University of Edinburgh
National Institute for Public Health and the Environment (RIVM)

Completed

Combustion Derived Air Pollution and Vascular Function

Endothelial Dysfunction

United Kingdom
University of Edinburgh
Umeå University

Completed

The Effect of a Retrofit Particle Trap on the Vascular Effects of Diesel Exhaust Inhalation

Heart Disease

Sweden
Fraunhofer-Institute of Toxicology and Experimental...
German Research Foundation

Completed

Study to Explore the Effects of Two Hour Inhalation of Ultrafine Carbon Black Particles on Airway Inflammation in Asthmatics

Asthma

Germany
Hadassah Medical Organization

Unknown

Clinical Evaluation of Esthetic Restorations Placed in Primary Molars With Composite Resin Enriched With Insoluble Anti Bacterial Nano Particles (IABN)

Dental Carious | Dental Filling

Israel

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