Search clinical trials for: mRNA-3927

Total 592 results

Novo Nordisk A/S

Completed

A Trial to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of NNC0215-0384 Administered to Subjects With Moderate to Severe Rheumatoid Arthritis

Inflammation | Rheumatoid Arthritis

Germany, Russian Federation, Poland, Hungary
Cardiology Research UBC

Recruiting

MYocarditis and/or Pericarditis Following mRNA COVID-19 VACCination National Surveillance Study (MYCOVACC)

Myocarditis | Pericarditis | Myocarditis Acute | Pericarditis Acute

Canada
Institute for Clinical and Experimental Medicine

Completed

IgG Antibodies After SARS-CoV-2 mRNA Vaccine in Kidney Transplantation (TASMANIA) (TASMANIA)

Kidney Transplantation

Czechia
University of Florida
National Cancer Institute (NCI)

Completed

Vaccine Therapy for the Treatment of Newly Diagnosed Glioblastoma Multiforme (ATTAC-II)

Glioblastoma | Glioblastoma Multiforme | Malignant Glioma | GBM | Astrocytoma, Grade IV

United States
University of Monastir

Not yet recruiting

mRNA Expression and Genetic Polymorphisms Affecting DRD3 (rs6280) and HTR2A (rs6313) in Bruxism

Bruxism
Novavax

Completed

Phase 3 Study of Novavax Vaccine(s) as Booster Dose After mRNA Vaccines

COVID-19

United States
Hospital Moinhos de Vento
Pfizer; Universidade Federal do Paraná; Inova Medical

Completed

A Real-world Evidence Study of BNT162b2 mRNA Covid-19 Vaccine in Brazil

Covid19

Brazil
George Washington University
National Institute on Minority Health and Health Disparities (NIMHD); Shenandoah... and other collaborators

Withdrawn

Impact of Anti-platelet Drug Exposure on Platelet mRNA Splicing in Healthy Subjects

Thrombosis; Artery

United States
ANRS, Emerging Infectious Diseases
LinKinVax; Vaccine Research Institute (VRI), France

Recruiting

Safety and Immunogenicity of a Sub-unit Protein CD40.RBDv Bivalent COVID-19 Vaccine, Adjuvanted or Not, as a Booster in Volunteers.

COVID-19

France
Mylan Pharmaceuticals Inc

Completed

Food BE Study Metformin Hydrochloride ER Tablets 500 mg and Glucophage XR 500 mg

Healthy

United States
Azienda Socio Sanitaria Territoriale di Cremona

Recruiting

Effectiveness of mRNA Covid-19 Vaccines on Cancer Patients:Observational Study. (ANTICOV) (ANTICOV)

Covid-19 | Cancer | Vaccine Response

Italy
Harald Wolf, MD
Medical Scientific Fund of the Mayor of Vienna

Completed

The Clinical Relevance of Micro RNAs in Mild Traumatic Brain Injury (mRNA)

Brain Injuries, Traumatic

Austria
ModernaTX, Inc.

Completed

Long-Term Follow-up Survey of COVID-19 Vaccine After Vaccination

Coronavirus Disease (COVID-19)

Japan
Guangdong 999 Brain Hospital
Jinan University Guangzhou; Beijing Tricision Biotherapeutics Inc; Trinomab Biotech...

Completed

Personalized Cellular Vaccine for Recurrent Glioblastoma (PERCELLVAC2) (PerCellVac2)

Glioblastoma

China
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Metformin Hydrochloride ER Tablets 750 mg and Glucophage® XR Tablets 750 mg

Healthy

United States
Pfizer

Recruiting

Use and Effectiveness of COVID-19 Vaccines Using State Vaccine Registries and Insurance Claims Data

COVID-19 | SARS-CoV-2 | Post-Acute COVID-19 Syndrome

United States
CureVac

Withdrawn

A Study to Evaluate the Immunogenicity and Safety of the SARS-CoV-2 mRNA Vaccine CVnCoV in Elderly Adults Compared to Younger Adults for COVID-19

Severe Acute Respiratory Syndrome | Covid19 | SARS-CoV-2 | Coronavirus
Sanofi Pasteur, a Sanofi Company

Completed

Study to Assess the Safety and Immunogenicity of Monovalent mRNA NA Vaccine in Adult Participants 18 Years of Age and Older

Healthy Volunteers | Influenza Immunization

United States
Karamanoğlu Mehmetbey University

Recruiting

Comparative Evaluation of Covid-19 Vaccines Response

COVID-19 Vaccines

Turkey
King's College Hospital NHS Trust
King's College London

Completed

Randomised Controlled Trial of Mechanistic Effects of Rifaximin in Cirrhosis and Chronic Hepatic Encephalopathy (RIFSYS)

Liver Cirrhosis | Hepatoencephalopathy, Early Fatal Progressive

United Kingdom
Shanghai BDgene Co., Ltd.
Eye & ENT Hospital of Fudan University

Completed

Safety and Efficacy of CRISPR/Cas9 mRNA Instantaneous Gene Editing Therapy to Treat Refractory Viral Keratitis

Cornea | Herpes Simplex Virus Infection | Viral Keratitis | Blindness Eye

China
Bausch Health Americas, Inc.

Completed

The Safety/Efficacy of Rifaximin With/Without Lactulose in Participants With A History of Recurrent Hepatic Encephalopathy

Hepatic Encephalopathy | Cirrhosis

United States
Cathay General Hospital
National Science Council, Taiwan

Completed

Comparison of Human Papillomavirus Integrated DNA and Messenger RNA in Cervical Neoplasia

Cervical Intraepithelial Neoplasia

Taiwan
University of Chicago
Idiopathic Pulmonary Fibrosis Clinical Research Network

Recruiting

A Study of the Natural Progression of Interstitial Lung Disease (ILD)

Idiopathic Pulmonary Fibrosis | Sarcoidosis | Interstitial Lung Diseases | Connective Tissue Disorder

United States
Mylan Pharmaceuticals Inc

Completed

Food Study Metformin Hydrochloride ER Tablets 750 mg and Glucophage XR 750 mg

Healthy

United States
Ludwig Institute for Cancer Research
Boehringer Ingelheim; MedImmune LLC; PharmaJet, Inc.; CureVac; Cancer Research Institute...

Completed

Phase 1/2 Study of Combination Immunotherapy and Messenger Ribonucleic Acid (mRNA) Vaccine in Subjects With NSCLC

NSCLC | Metastatic Non-small Cell Lung Cancer

United States
Guangdong 999 Brain Hospital
Jinan University Guangzhou; Beijing Tricision Biotherapeutics Inc; Trinomab Biotech...

Completed

Personalized Cellular Vaccine for Glioblastoma (PERCELLVAC) (PERCELLVAC)

Glioblastoma

China
CNBG-Virogin Biotech (Shanghai) Ltd.

Recruiting

A PhaseⅡ Study to Evaluate the Safety and Immunogenicity of COVID-19 Vaccine

SARS-CoV-2 Infection

China
Murdoch Childrens Research Institute
Coalition for Epidemic Preparedness Innovations; The Peter Doherty Institute...

Completed

Evaluation of Full Versus Fractional Doses of COVID-19 Vaccines Given as a Booster in Adults in Australia - Mongolia, Indonesia, Australia Coronavirus (MIACoV). (MIACoV)

COVID-19

Australia
Serge Thal

Completed

Effect of Different SARS-CoV-2 Vaccine Schedules and Vaccination Intervals on Reactogenicity and Humoral Immunogenicity

SARS-CoV2 Infection | Tolerance | Immunisation Reaction | Antibody Hypersensitivity

Germany
GlaxoSmithKline

Completed

A Study on the Immune Response and Safety of the Shingles Vaccine and the Influenza Vaccine When Either is Given to Healthy Adults at the Same Time or Following a COVID-19 Booster Vaccine

Herpes Zoster

United States
University Health Network, Toronto

Completed

Third Dose of Moderna COVID-19 Vaccine in Transplant Recipients

Covid19 | Vaccine Response Impaired | Immune Suppression

Canada
University of Melbourne
Southern Star Research Pty Ltd.

Completed

Safety and Immune Response of Adjuvanted SARS-CoV-2 (COVID-19) Beta Variant RBD Recombinant Protein (DoCo-Pro-RBD-1 + MF59®) and mRNA (MIPSCo-mRNA-RBD-1) Vaccines in Healthy Adults

SARS-CoV-2

Australia
BioNTech SE
Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.

Completed

Safety and Immunogenicity of SARS-CoV-2 mRNA Vaccine (BNT162b1) in Chinese Healthy Subjects

SARS-CoV-2

China
University of Arkansas

Terminated

The Expression of PTEN Protein and mRNA in Malignant Cells of Chronic Myelomonocytic Leukemia

Chronic Myelomonocytic Leukemia

United States
Nobuyuki Katori
Baxter Healthcare Corporation

Unknown

Desflurane-induced Myocardial Protection

Aortic Valve Stenosis

Japan
AIM Vaccine Co., Ltd.
Zhejiang Provincial Center for Disease Control and Prevention

Not yet recruiting

A Phase II Clinical Trial to Evaluate the Immunogenicity and Safety of SARS-CoV-2 Bivalent mRNA Vaccine (LVRNA021)

SARS-CoV-2

China
Mylan Pharmaceuticals Inc

Completed

Fasting BE Study of Metformin Hydrochloride ER Tablets 500 mg and Glucophage® XR Tablets 500 mg

Healthy

United States
National Institute of Allergy and Infectious Diseases...

Recruiting

NADPH Oxidase Correction in mRNA-transfected Granulocyte-enriched Cells in Chronic Granulomatous Disease (CGD)

Chronic Granulomatous Disease | Infection

United States
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Active, not recruiting

A Study of SARS-CoV-2 mRNA Vaccine (SYS6006) in Chinese Healthy Older Adults.

SARS-CoV-2

China
Tata Memorial Hospital
Ministry of Science and Technology, India

Unknown

HPV E6/E7 mRNA Versus HPV DNA as Triage for Cervical Cancer Screening (PODBT)

Cervix Cancer | CIN

India
ModernaTX, Inc.

Recruiting

Study of mRNA-4359 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With Advanced Solid Tumors

Advanced Solid Tumors

United States, United Kingdom, Australia, Spain
Jules Bordet Institute
Roche Pharma AG

Terminated

COVID-19: Immune Response in Patients With Cancer Undergoing mRNA Vaccination Against SARS-CoV-2 (I-SPARC)

Cancer

Belgium
BioNTech SE
Pfizer

Completed

A Phase 1/2/3 Study to Evaluate the Safety, Tolerability, and Immunogenicity of an RNA Vaccine Candidate Against COVID-19 in Healthy Children

SARS-CoV-2 Infection, COVID-19

United States, Spain, Finland, Poland, Mexico, Brazil
Assistance Publique - Hôpitaux de Paris
Institut National de la Santé Et de la Recherche Médicale, France; National... and other collaborators

Completed

Transcriptome Assessment After Cardiac Arrest (OMECARD)

Out-Of-Hospital Cardiac Arrest After Initial Successful Resuscitation

France
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Metformin Hydrochloride ER Tablets 500 mg and Glucophage® XR Tablets 500 mg

Healthy

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Lymph Node Aspiration to Decipher the Immune Response of Beta-variant Recombinant Protein Booster Vaccine (VidPrevtyn Beta, Sanofi) Compared to a Bivalent mRNA Vaccine (Comirnaty Original/Omicron BA.4-5, BioNTech-Pfizer) in Adults Previously Vaccinated With at Least 3 Doses of COVID-19 mRNA Vaccine. (LymphoBOOST)

COVID-19

France
Qihan Li

Not yet recruiting

Study of Ameliorating Effect of COVID-19 mRNA Vaccine in Individuals Immunized With Inactivated Vaccine (COVID-19)

SARS-CoV-2 Acute Respiratory Disease
University Hospital, Strasbourg, France

Recruiting

Covid Vaccination in Liver Transplantation (VACCHEPA)

COVID-19

France
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Sample Collections From the Airways of Asthmatic Patients

Asthma

United States

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