Search clinical trials for: malignant

Total 5326 results

Xinqiao Hospital of Chongqing

Recruiting

A Real-world Study of the Efficacy and Safety of ICIs as First-line Therapy for Advanced Malignancies

Artificial Intelligence | Malignant Tumor | Immunotherapy

China
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Recruiting

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

Metastatic Malignant Neoplasm in the Liver | Metastatic Colorectal Carcinoma | Stage IV Colorectal Cancer AJCC v8 | Unresectable Colorectal Carcinoma

United States
Biotheus Inc.

Recruiting

Clinical Study of PM1003 in Phase I/IIa Treatment of Advanced Malignant Solid Tumors

Advanced Solid Tumors

China
Aurigene Discovery Technologies Limited

Recruiting

A Phase 1 Clinical Trial of AUR106 in Patients With Relapsed Advanced Malignancies (JIVAN)

Kidney Cancer | Gastric Cancer | Non Small Cell Lung Cancer | Colon Cancer | Urothelial Carcinoma | Relapse | Esophagus Cancer | Advanced Malignant Neoplasm

India
Zai Lab (Hong Kong), Ltd.
Merck Sharp & Dohme LLC; Zai Biopharmaceutical (Shanghai) Co., Ltd.

Recruiting

A Phase 1 Study of ZL-1218 in Subjects With Advanced Solid Tumors

Malignant Solid Tumor

United States, Spain, China
Florida International University
National Institute on Minority Health and Health Disparities (NIMHD); Nicklaus... and other collaborators

Recruiting

Ex Vivo Drug Sensitivity Testing and Multi-Omics Profiling

Recurrent Childhood Ependymoma | Recurrent Childhood Acute Lymphoblastic Leukemia | Recurrent Childhood Acute Myeloid Leukemia | Refractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Recurrent Childhood Rhabdomyosarcoma | Recurrent Childhood Soft Tissue Sarcoma | Recurrent Childhood Large... and other conditions

United States
Proteocyte Diagnostics Inc.
The University of Texas Health Science Center, Houston; University of Alabama... and other collaborators

Recruiting

Evaluation of Oral Potentially Malignant Disorders (OPMDs) With STRATICYTE™

Mouth Diseases

United States
Fudan University

Recruiting

Postoperative Effects of Different Enterostomy Approaches

Colorectal Cancer | Colorectal Neoplasms Malignant | Intestinal Neoplasms, Malignant

China
Mirati Therapeutics Inc.

Recruiting

Trial of Two Adagrasib Dosing Regimens in NSCLC With KRAS G12C Mutation (KRYSTAL 21)

Metastatic Cancer | Advanced Cancer | Malignant Neoplasm of Lung

Korea, Republic of, United States, Turkey, France, Taiwan, Spain
Shandong Suncadia Medicine Co., Ltd.

Recruiting

Phase I Clinical Study of HRS-2189 in the Treatment of Patients With Advanced Malignant Tumors

Advanced Malignant Tumor

China
Sociedad de Lucha Contra el Cáncer del Ecuador

Not yet recruiting

5-Aminolevulinic Acid (5-ALA) Gliolan®: Usage Increase Proposal for Neurosurgical Procedures in High-Grade Gliomas

Glioma | Neoplasms, Neuroepithelial | Neuroectodermal Tumors | Central Nervous System Neoplasms | Brain Tumor | High Grade Glioma | Glioma, Malignant | Neoplasm Malignant | Photosensitizing Agents | Tumour, Residual | Brain Neoplasms, Adult, Malignant

Ecuador
Bio-Thera Solutions

Recruiting

Assessment of Safety, Tolerability and Pharmacokinetics With BAT8010 for Injection in Advanced Malignant Solid Tumors Patients

Advanced or Metastatic Solid Tumors

China
Zhejiang University
UTC Therapeutics Inc.

Recruiting

UCLM802 (Anti-Mesothelin CAR-T) Cell Injection in Patients With Mesothelin-positive Advanced Malignant Solid Tumors

Mesothelin-positive Advanced Malignant Solid Tumors

China
Telix Pharmaceuticals (Innovations) Pty Limited
Grand Pharmaceutical (China) Co., Ltd.

Recruiting

68Ga-PSMA-11 Efficacy in Detecting BCR Prostate Cancer in Chinese Patients

Prostate Cancer | Biochemical Recurrence of Malignant Neoplasm of Prostate | BCR Prostate Carcinoma

China
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

RefleXion PET/CT Imaging Performance in Patients With Various Malignancies

Malignant Solid Neoplasm | Hematopoietic and Lymphoid System Neoplasm

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Cemiplimab for the Treatment of Untreated Brain Metastases From PD-L1 >= 50% Non-Small Cell Lung Cancer

Metastatic Lung Non-Small Cell Carcinoma | Stage IV Lung Cancer AJCC v8 | Metastatic Malignant Neoplasm in the Brain

United States
Centre Hospitalier Universitaire, Amiens

Not yet recruiting

Intratumoral Gemcitabine, Paclitaxel, Carboplatine and Intravenous Nivolumab for Locally Recurrence of Head and Neck Cancers (NIVOCHIMLOC)

Squamous Cell Carcinoma of the Head and Neck | Paclitaxel | Nivolumab | Carboplatin

France
Zhongnan Hospital

Recruiting

Integrin αvβ6-targeted PET in Malignant Tumors

Malignant Neoplasm | PET/CT | Integrin αvβ6

China
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Positron Emission Tomography (PET) Guided Stereotactic Body Radiation Therapy for the Treatment of Oligoprogressive Non-small Cell Lung Cancer, Melanoma, and Renal Cell Carcinoma

Malignant Solid Neoplasm | Melanoma | Renal Cell Carcinoma | Lung Non-Small Cell Carcinoma

United States
Pietro Mortini, MD, Prof.

Recruiting

Characterization of Circulating and Tumor-infiltrating Immune Cells in Malignant Brain Tumors

Brain Tumor, Primary | Brain Tumor - Metastatic

Italy
Zhejiang University
Yake Biotechnology Ltd.

Recruiting

CD7 CAR-T Bridging to alloHSCT for R/R CD7+Malignant Hematologic Diseases

Neoplasms | Hematologic Diseases

China
Guangzhou Institute of Respiratory Disease

Recruiting

Almonertinib in the First-line Treatment of Patients of NSCLC With Poor Performance Status

Poor Performance Status | Malignant Tumor of Lung

China
UNC Lineberger Comprehensive Cancer Center

Recruiting

Measuring Changes in Body Composition and Physical Function in Patients With Childhood Cancers

Cancer | Malignant Neoplasm

United States
Shanghai Jun Pai Ying Shi Therapeutics Co., Ltd.
Sponsor GmbH

Recruiting

A Clinical Study of IMP4297 Capsule (JS109) Combined With Irinotecan in the Treatment of Advanced Malignant Solid Tumors

Advanced Solid Tumors

China
Power Life Sciences Inc.

Not yet recruiting

Studying the Clinical Trial Experiences of Patients With Mesothelioma

Mesothelioma
Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Recruiting

A Study of SHR-4602 in Subjects With Advanced Malignant Solid Tumors

Advanced Solid Tumor

China
Mayo Clinic

Recruiting

Associations Between Chemotherapy-Induced Nausea in Patients With Genitourinary, Sarcoma or Melanoma Cancers and Changes in Gut Microbiome: Potential for Precision Therapeutics

Melanoma | Sarcoma | Prostate Cancer | Bladder Cancer | Bladder Carcinoma | Prostate Carcinoma | Testicular Cancer | Genitourinary System Carcinoma | Malignant Testicular Neoplasm

United States
National Cancer Institute (NCI)

Recruiting

Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable Cancers

Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Metastatic Colorectal Carcinoma | Stage IV Colorectal Cancer AJCC v8 | Unresectable Colorectal Carcinoma

United States
Sichuan Baili Pharmaceutical Co., Ltd.
Baili-Bio (Chengdu) Pharmaceutical Co., Ltd.

Recruiting

A Study of BL-B01D1 in Patients With Multiple Solid Tumors, Including Recurrent or Metastatic Gynecological Malignancies

Solid Tumor | Gynecological Malignant Tumor

China
Chinese University of Hong Kong

Not yet recruiting

EUS-guided Hepatico-gastrostomy With Hot Giobor

Malignant Biliary Obstruction

Hong Kong
Northwestern University
National Cancer Institute (NCI); Varian Medical Systems

Recruiting

Stereotactic Body Radiation Therapy Planning With Artificial Intelligence-Directed Dose Recommendation for Treatment of Primary or Metastatic Lung Tumors, RAD-AI Study

Lung Non-Small Cell Carcinoma | Lung Carcinoma | Stage II Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage I Lung Cancer AJCC v8 | Metastatic Malignant Neoplasm in the Lung

United States
Mayo Clinic

Recruiting

Aldesleukin With Nivolumab and Standard Chemotherapy for Treatment of Gastric Cancer With Peritoneal Metastasis

Gastric Adenocarcinoma | Clinical Stage IV Gastric Cancer AJCC v8 | Gastroesophageal Junction Adenocarcinoma | Metastatic Gastric Carcinoma | Metastatic Malignant Neoplasm in the Peritoneum

United States
Instituto Nacional de Cancer, Brazil

Recruiting

Benefits of Morphine Gel for Pain Reduction in Patients With Cancer Wounds (MorphineGEL)

Wounds and Injuries | Cancer Head Neck | Cancer, Breast | Cancer Pain

Brazil
Brno University Hospital
Masaryk University

Recruiting

Catheter Dislocation and the Influence of Different Catheter Fixation in Pediatric Patients (FIXATION)

Catheter Complications

Czechia
University of Florida
Florida Department of Health

Recruiting

Alpha/Beta T Cell and CD19+ B Cell Depletion in Allogeneic Stem Cell Transplantation in Patients With Malignant Diseases

Lymphoma, Non-Hodgkin | Acute Myeloid Leukemia | Myelodysplastic Syndromes | Juvenile Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | Chronic Myeloid Leukemia | Lymphoma, Hodgkin

United States
Chinese University of Hong Kong
Roche Diagnostics

Recruiting

Comparing N-terminal-proB-type Natriuretic Peptide With Other Criteria in Pleural Fluid Analysis

Heart Failure | Infections | Renal Failure | Cirrhosis | Fluid Overload | Pleural Effusion | Malignant Neoplasm | Hypoalbuminemia

Hong Kong
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Sentinel Lymph Node Biopsy in Ocular Surface and Adnexal Cancers (BLS)

Conjunctival Melanoma | Porocarcinoma | Ocular Surface Squamous Neoplasia | Merkel Cell Carcinoma, Unspecified | Ocular Sebaceous Carcinoma | Ocular Basal Cell Carcinoma

Italy
Medical College of Wisconsin

Recruiting

MCW Alpha/Beta T-Cell and B-Cell Depletion With Targeted ATG Dosing

Leukemia | Burkitt Lymphoma | Lymphoblastic Lymphoma | Myelodysplasia | Acute Myeloid Leukemia in Remission | Acute Lymphoblastic Leukemia in Remission | Chronic Myelogenous Leukemia - Chronic Phase | Chronic Myelogenous Leukemia, Accelerated Phase | Biphenotypic Acute Leukemia | Burkitt Leukemia | Chronic... and other conditions

United States
CRISPR Therapeutics AG

Recruiting

A Safety and Efficacy Study Evaluating CTX131 in Adult Subjects With Relapsed or Refractory Solid Tumors

Clear Cell Renal Cell Carcinoma | Pancreatic Adenocarcinoma | Cervical Carcinoma | Malignant Pleural Mesothelioma | Esophageal Carcinoma

United States
Zhejiang Cancer Hospital
Sun Yat-sen University; Shanghai Zhongshan Hospital; Fujian Cancer Hospital; RenJi... and other collaborators

Recruiting

Multi-omics Study of Tongue Coating in Malignant Tumors of Digestive Tract

Malignant Tumors of Digestive Tract

China
University of Southern California
National Cancer Institute (NCI); Auransa, Inc.

Recruiting

AU409 for the Treatment of Advanced Primary Liver Cancers or Solid Tumor With Liver Metastatic Disease

Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Advanced Hepatocellular Carcinoma | Metastatic Malignant Neoplasm in the Liver | Stage III Hepatocellular Carcinoma AJCC v8 | Stage IV Hepatocellular Carcinoma AJCC v8 | Advanced Cholangiocarcinoma

United States
Zagazig University

Recruiting

Multihole Fully Covered Metallic Stents in the Management of Malignant Biliary Obstruction

Malignant Biliary Obstruction

Egypt
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

e-Health Intervention (Day-by-Day) for the Management of Fear of Progression in Women With Stage III or IV Gynecologic Cancer: A Pilot Study

Stage III Uterine Corpus Cancer AJCC v8 | Stage IV Uterine Corpus Cancer AJCC v8 | Malignant Female Reproductive System Neoplasm | Stage III Cervical Cancer AJCC v8 | Stage IV Cervical Cancer AJCC v8 | Stage IV Vulvar Cancer AJCC v8 | Stage III Ovarian Cancer AJCC v8 | Stage IV Ovarian Cancer AJCC... and other conditions

United States
Cancer Institute and Hospital, Chinese Academy...
UTC Therapeutics Inc.

Not yet recruiting

MSLN-targeted CAR-T Cells in Solid Tumors.

Mesothelin-positive Advanced Malignant Solid Tumors
CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co....

Not yet recruiting

A Study of Clevidipine Butyrate Injectable Emulsion in the Treatment of Hypertensive Emergency and Sub-emergency

Hypertensive Emergency
Alpha Tau Medical LTD.

Recruiting

A Study of Diffusing Alpha Radiation Therapy for Target Treatments of Malignant Tumors

Malignant Tumor

Israel
China-Japan Friendship Hospital

Recruiting

The Effectiveness and Safety of Ultrasound Elastography Guided Pleural Biopsy in the Differential Diagnosis of Benign and Malignant Pleural Effusion

Pleural Effusion

China
Nanjing Leads Biolabs Co.,Ltd

Recruiting

A Phase I/II Clinical Trial of LBL-033 in the Treatment of Advanced Malignant Tumors

Advanced Malignant Tumors

China
Vejle Hospital

Not yet recruiting

The Impact of a Patient Decision Aid on Treatment Choices for Patients With an Unexpected Malignant Colorectal Polyp

Colorectal Cancer | Colonic Polyp | Colorectal Polyp | Shared Decision Making | Decision Aids | Rectal Polyp
Peking University
UTC Therapeutics Inc.

Not yet recruiting

UCLM802 (Anti-Mesothelin CAR-T) Cell Injection in Patients With Mesothelin-positive Advanced Malignant Solid Tumors

Solid Tumor

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