Search clinical trials for: metastatic childhood soft tissue sarcoma

Total 76263 results

National Cancer Institute (NCI)

Terminated

Continuous 24h Intravenous Infusion of Mithramycin, an Inhibitor of Cancer Stem Cell Signaling, in People With Primary Thoracic Malignancies or Carcinomas, Sarcomas or Germ Cell Neoplasms With Pleuropulmonary Metastases

Neoplasms, Germ Cell and Embryonal | Lung Neoplasms | Esophageal Neoplasms | Thymus Neoplasms | Mesothelioma

United States
GWT-TUD GmbH

Completed

Geriatric Assessmen of Elderly "Unsuited" Patients Receiving Trabectedin in First Line Treatment For Advanced Soft Tissue Sarcomas (STS) (E-TRAB)

Advanced Soft-tissue Sarcoma | Metastatic Soft-tissue Sarcoma

Germany, Austria, Switzerland
Children's Oncology Group
National Cancer Institute (NCI)

Completed

DNA Biomarkers in Tissue Samples From Patients With Osteosarcoma

Recurrent Osteosarcoma | Metastatic Osteosarcoma | Localized Osteosarcoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Withdrawn

Lurbinectedin With or Without Irinotecan in Treating Patients With Relapsed or High Risk Metastatic Ewing Sarcoma

Recurrent Ewing Sarcoma | Metastatic Ewing Sarcoma

United States
National Cancer Institute (NCI)

Completed

Glembatumumab Vedotin in Treating Patients With Recurrent or Refractory Osteosarcoma

Recurrent Osteosarcoma

United States, Canada, Puerto Rico
Azienda Ospedaliera Ospedale Infantile Regina Margherita...

Completed

Study of Effectiveness of GEMDOX in Relapsed Osteosarcoma

Osteosarcoma Recurrent | Osteosarcoma Metastatic

Italy
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Vincristine, Dactinomycin, and Cyclophosphamide With or Without Radiation Therapy in Treating Patients With Newly Diagnosed Low-Risk Rhabdomyosarcoma

Adult Rhabdomyosarcoma | Embryonal Childhood Rhabdomyosarcoma | Embryonal-botryoid Childhood Rhabdomyosarcoma | Previously Untreated Childhood Rhabdomyosarcoma

United States, Canada, Australia, New Zealand, Puerto Rico, Switzerland
PharmaMar

Completed

Study of Zalypsis® (PM00104) in Patients With Unresectable Locally Advanced and/or Metastatic Ewing Family of Tumors (EFT) Progressing After at Least One Prior Line of Chemotherapy

Ewing's Sarcoma | Primitive Neuroectodermal Tumor (PNET) | Askin's Tumor of the Chest Wall | Extraosseous Ewing's Sarcoma (EOE)

France, United States, Italy
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb

Completed

Phase II Evaluation of Low-Dose Oral Etoposide for the Treatment of Relapsed or Progressed AIDS-Related Kaposi's Sarcoma After Systemic Chemotherapy

HIV Infections | Sarcoma, Kaposi

United States
European Organisation for Research and Treatment...
Boehringer Ingelheim

Terminated

Ph II Nintedanib vs. Ifosfamide in Soft Tissue Sarcoma (ANITA)

Sarcoma, Soft Tissue

France, Belgium, Poland, Spain, Lithuania, Netherlands, United Kingdom
The University of Hong Kong

Unknown

The Impact of Cancer on the Physical and Psychosocial Well-being Among Childhood Osteosarcoma Survivors

Childhood Osteosarcoma

Hong Kong
Grupo Espanol de Investigacion en Sarcomas

Completed

ABCB1/P-glycoprotein Expression Influence on Non-metastatic Osteosarcoma of the Extremities

Osteosarcoma

Spain
Brown University
Actuate Therapeutics Inc.

Withdrawn

A Phase 2 Study of 9-ING-41Combined With Chemotherapy in Adolescents and Adults With Advanced Sarcomas

Sarcoma | Soft Tissue Sarcoma | Leiomyosarcoma | High Grade Sarcoma | Liposarcoma | Rhabdomyosarcoma | Angiosarcoma | Bone Sarcoma | Synovial Sarcoma | Undifferentiated Pleomorphic Sarcoma | Metastatic Sarcoma | Myxofibrosarcoma | Spindle Cell Sarcoma

United States
National Cancer Institute (NCI)

Completed

Temozolomide and Irinotecan Hydrochloride With or Without Bevacizumab in Treating Young Patients With Recurrent or Refractory Medulloblastoma or CNS Primitive Neuroectodermal Tumors

Pineoblastoma | Recurrent Medulloblastoma | Refractory Medulloblastoma | Refractory Peripheral Primitive Neuroectodermal Tumor | Central Nervous System Neoplasm | Recurrent Primitive Neuroectodermal Tumor

United States, Canada, Puerto Rico, Australia, New Zealand
GlaxoSmithKline

Completed

A Pilot Study of Genetically Engineered NY-ESO-1 Specific NY-ESO-1ᶜ²⁵⁹T in HLA-A2+ Patients With Synovial Sarcoma (NY-ESO-1)

Neoplasms

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Pembrolizumab and Doxorubicin Hydrochloride in Treating Patients With Sarcoma That is Metastatic or Cannot Be Removed by Surgery

Sarcoma

United States
NKGen Biotech, Inc.

Withdrawn

Safety and Preliminary Efficacy of SNK01 in Combination With Trastuzumab or Cetuximab in Subjects With Advanced HER2 or EGFR Cancers

Sarcoma | Cervical Cancer | Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | Metastatic Cancer | Bladder Cancer | Triple Negative Breast Cancer | Advanced Solid Tumor | HER2-positive Breast Cancer | Head and Neck Squamous Cell Carcinoma | EGF-R Positive Non-Small... and other conditions
Dana-Farber Cancer Institute

Terminated

Stereotactic Body Radiotherapy (SBRT) for Pulmonary Metastases in Ewing Sarcoma, Rhabdomyosarcoma, and Wilms Tumors

Sarcoma | Soft Tissue Sarcoma | Clear Cell Renal Cell Carcinoma | Osteosarcoma | Sarcoma, Ewing | Ewing Sarcoma | Rhabdoid Tumor | Renal Tumor | Rhabdomyosarcoma | Wilms Tumor | Non-Rhabdomyosarcoma Soft Tissue Sarcoma, Nos

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Completed

High-Dose Chemotherapy With or Without Total-Body Irradiation Followed by Autologous Stem Cell Transplant in Treating Patients With Hematologic Cancer or Solid Tumors

Unspecified Childhood Solid Tumor, Protocol Specific | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma and other conditions

United States
Italian Sarcoma Group
AstraZeneca; PharmaMar; Istituto Di Ricerche Farmacologiche Mario Negri

Completed

Trabectedin Plus Olaparib in Metastatic or Advanced Sarcomas (TOMAS) (TOMAS)

Soft Tissue Sarcoma | Bone Tumor

Italy
George Clinical Pty Ltd
Novartis

Terminated

Study of Pazopanib in the Treatment of Osteosarcoma Metastatic to the Lung

Osteosarcoma | Metastatic Osteosarcoma

United States
Centre Oscar Lambret
Bayer

Completed

Phase II Study of Regorafenib in Metastatic Soft Tissue Sarcoma (REGO-SARC)

Sarcoma

France, Austria
National Cancer Institute (NCI)

Completed

Talazoparib and Temozolomide in Treating Younger Patients With Refractory or Recurrent Malignancies

Recurrent Malignant Solid Neoplasm | Childhood Solid Neoplasm | Recurrent Childhood Central Nervous System Neoplasm | Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Adult Solid Neoplasm | Refractory Central Nervous System Neoplasm

United States
Massachusetts General Hospital
Dana-Farber Cancer Institute; PharmaMar

Completed

A Phase II Multi-Strata Study of PM01183 as a Single Agent or in Combination With Conventional Chemotherapy in Metastatic and/or Unresectable Sarcomas

Metastatic Sarcoma

United States
M.D. Anderson Cancer Center
Bayer

Completed

Phase I Dose Escalation of Monthly Intravenous Ra-223 Dichloride in Osteosarcoma

Sarcoma

United States
Institut Bergonié
French Sarcoma Group

Completed

METASARC: Patterns of Care and Outcomes in METAstatic Soft Tissue SARComa (METASARC)

Sarcoma | Chemotherapy | Metastases

France
Institut Bergonié
Ministry of Health, France; PharmaMar

Terminated

Efficacy and Safety of Plitidepsin in Patients With Advanced Unresectable or Metastatic, Relapsed/Refractory, Dedifferentiated Liposarcoma (DLPS): an Exploratory Phase II Multicenter Trial (APLIPO)

Adult Patients With Unresectable Locally Advanced or Metastatic, Relapsed/Refractory Dedifferentiated Liposarcoma

France
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Dalteparin in Preventing DVT in Participants With Cancer

Soft Tissue Sarcoma | Lymphoma | Plasma Cell Myeloma | Bone Sarcoma | Femur Fracture | Metastatic Neoplasm | Pathologic Fracture

United States
Oncurious NV
Beat Childhood Cancer

Completed

A Study of TB-403 in Pediatric Subjects With Relapsed or Refractory Medulloblastoma

Relapsed or Refractory Medulloblastoma (MB), Neuroblastoma (NB), Ewing Sarcoma (ES) and Alveolar Rhabdomyosarcoma (ARMS)

United States
Mohammed Milhem, MBBS
University of Iowa; University of Iowa Adolescent and Young Adult (AYA) Cancer... and other collaborators

Terminated

Gemcitabine Plus Ascorbate for Sarcoma in Adults

Sarcoma | Soft Tissue Sarcoma | Bone Sarcoma | Metastatic Bone Tumor | Unresectable Soft Tissue Sarcoma

United States
Peking University People's Hospital
Peking University Shougang Hospital

Completed

Osteosarcoma With Resectable Pulmonary Metastasis: A Retrospective Study

Pulmonary Disease | Osteosarcoma Metastatic | Survival | Resectable Sarcoma

China
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI); Children's Hospital of Michigan

Terminated

Study of Fixed vs. Flexible Filgrastim to Accelerate Bone Marrow Recovery After Chemotherapy in Children With Cancer

Unspecified Childhood Solid Tumor, Protocol Specific | Osteosarcoma | Neuroblastoma | Retinoblastoma | Recurrent/Refractory Childhood Hodgkin Lymphoma | Wilms Tumor and Other Childhood Kidney Tumors | Childhood Choroid Plexus Tumor | Childhood Soft Tissue Sarcoma | Childhood Medulloblastoma | Childhood... and other conditions

United States
St. Jude Children's Research Hospital
CURE Childhood Cancer, Inc.

Completed

A Study of CD45RA+ Depleted Haploidentical Stem Cell Transplantation in Children With Relapsed or Refractory Solid Tumors and Lymphomas

Melanoma | Lymphoma | Renal Cell Carcinoma | Ewing Sarcoma | Rhabdoid Tumor | Neuroblastoma | Rhabdomyosarcoma | Wilms Tumor | Germ Cell Tumor | Gastrointestinal Tumor | Hepatic Tumor | Clear Cell Carcinoma | Non-rhabdomyosarcoma

United States
Oslo University Hospital
Merck Sharp & Dohme LLC; Italian Sarcoma Group

Terminated

A Study of Pembrolizumab in Patients With Relapsed Or Metastatic Osteosarcoma Not Eligible for Curative Surgery (PROMO)

Osteosarcoma

Norway, Italy
National Cancer Institute (NCI)

Completed

Eligibility Screening for a NCI Pediatric Oncology Branch Research Study

Osteosarcoma | Acute Lymphoblastic Leukemia | Ewing Sarcoma | Neurofibromatosis Type 1 | Neuroblastoma

United States
Washington University School of Medicine

Withdrawn

Lattice Stereotactic Body Radiation Therapy (Lattice SBRT) for Localized Unresectable or Metastatic Conventional Type Chondrosarcoma

Metastatic Chondrosarcoma
Eli Lilly and Company

Completed

A Study of Olaratumab (LY3012207), Doxorubicin, and Ifosfamide in Participants With Advanced or Metastatic Soft Tissue Sarcoma

Soft Tissue Sarcoma

United States, Germany, Italy
European Organisation for Research and Treatment...
PharmaMar

Terminated

Trabectedin Maintenance Post 1st-line in STS

Sarcoma, Soft Tissue

France, Germany, Spain, Netherlands, Poland, United Kingdom
Sidney Kimmel Comprehensive Cancer Center at Johns...

Completed

Stereotactic Radiation Therapy for Pediatric Sarcomas

Sarcoma | Metastatic Disease | Bony Sites

United States
Eli Lilly and Company

Completed

A Study of LY3039478 in Participants With Advanced or Metastatic Solid Tumors

Soft Tissue Sarcoma | Breast Cancer | Solid Tumor | Cholangiocarcinoma | Colon Cancer

United States, France, Spain, Denmark
Washington University School of Medicine
Novartis Pharmaceuticals

Completed

Pazopanib as Front-Line Therapy in Patients With Non-Resectable or Metastatic Soft Tissue Sarcomas Who Are Not Candidates for Chemotherapy

Soft Tissue Sarcoma | Sarcoma, Soft Tissue

United States
Jonsson Comprehensive Cancer Center

Completed

PET Scan Combined With CT Scan in Evaluating Treatment Response in Patients Undergoing Treatment for Bone Cancer or Soft Tissue Sarcoma

Sarcoma

United States
Grupo Espanol de Investigacion en Sarcomas
GlaxoSmithKline

Completed

Activity and Tolerability of Pazopanib in Advanced and/or Metastatic Liposarcoma. A Phase II Clinical Trial

Advanced and / or Metastatic Liposarcoma

Spain, Germany
Immune Design
Genentech, Inc.

Terminated

Study to Compare the Safety and Efficacy of CMB305 With Atezolizumab to Atezolizumab Alone in Participants With Sarcoma (IMDZ-C232/V943A-002)

Sarcoma | Myxoid/Round Cell Liposarcoma | Liposarcoma | Synovial Sarcoma | Recurrent Adult Soft Tissue Sarcoma | Metastatic Sarcoma | Locally Advanced Sarcoma

United States
Peking University People's Hospital
Xijing Hospital; Peking Union Medical College Hospital; Chinese PLA General Hospital and other collaborators

Withdrawn

Pegylated Liposomal Doxorubicin Versus Pirarubicin Plus Ifosfamide, Dacarbazine in Locally Advanced, Unresectable or Metastatic Soft-tissue Sarcoma (PDVPSTS)

Toxicity | Overall Survival | Progression-free Survival

China
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Alisertib in Treating Young Patients With Recurrent or Refractory Solid Tumors or Leukemia

Recurrent Childhood Acute Lymphoblastic Leukemia | Recurrent Childhood Acute Myeloid Leukemia | Recurrent Neuroblastoma | Recurrent Osteosarcoma | Hepatoblastoma | Recurrent Childhood Rhabdomyosarcoma | Recurrent Childhood Kidney Neoplasm | Previously Treated Childhood Rhabdomyosarcoma | Recurrent Childhood... and other conditions

United States, Canada
Celgene

Completed

Bioequivalence & Food Effect Study in Patients With Solid Tumor or Hematologic Malignancies

Melanoma | Sarcoma | Neoplasms | Lymphoma | Renal Cell Carcinoma | Acute Myeloid Leukemia | Myelodysplastic Syndromes | Leukemia | Breast Cancer | Small Cell Lung Cancer | Multiple Myeloma | Hodgkin's Lymphoma | Non-Hodgkin's Lymphoma | Non-Small Cell Lung Cancer | Osteosarcoma | Glioblastoma Multiforme | Metastatic Breast... and other conditions

United States
Fudan University

Unknown

PLD and IFO As First-line Treatment for Patients With Advanced or Metastatic STS

Soft Tissue Sarcoma

China
Immune Design

Terminated

A Phase 3, Randomized, Double-blind, Placebo-controlled Study For Subjects With Locally-advanced Unresectable or Metastatic Synovial Sarcoma (V943-003, IMDZ-04-1702)

Sarcoma | Soft Tissue Sarcoma | Cancer | Synovial Sarcoma | Metastatic Sarcoma

United States, Canada
NCIC Clinical Trials Group

Completed

Flavopiridol in Treating Patients With Recurrent, Locally Advanced, or Metastatic Soft Tissue Sarcoma

Sarcoma

Canada, United States

Search clinical trials for: metastatic childhood soft tissue sarcoma

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Montenegro

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations