Search clinical trials for: open

Total 8536 results

Novartis Pharmaceuticals

Recruiting

A Phase I/II, Open-label, Multi-center Study of [225Ac]Ac-PSMA-R2 in Men With PSMA-positive Prostate Cancer With or Without Prior 177Lu-PSMA Radioligand Therapy.

Metastatic Castration-resistant Prostate Cancer (mCRPC)

France
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

4 Courses vs 2 Courses of Pembrolizumab Combined With Carboplatin and Albumin-binding Paclitaxel of Neoadjuvant Therapy in HNSCC (HNC-SYSU-002)

Oral Cancer | HNSCC | PD-1

China
Sohag University

Not yet recruiting

Outcome of Surgical Fixation of Multiple Fractured Ribs at Sohag University Hospital

Multiple Fractures of Ribs
Baylor College of Medicine

Recruiting

Auricular Acupuncture As Part Of A Multimodal Regimen After Distal Radius Open Reduction and Internal Fixation

Pain, Postoperative | Radius Fracture Distal

United States
University of California, Los Angeles

Not yet recruiting

Open Trial of Biofeedback for Respiratory Symptoms

Shortness of Breath/Dyspnea
Sanofi

Recruiting

A Phase 1/Phase 2 Open-label Study to Evaluate the Safety, Tolerability, and Efficacy of a Single Intravenous Administration of SAR444836 in Adult Participants With Phenylketonuria

Phenylketonuria

Turkey, United States
Ain Shams University

Recruiting

Arthroscopic Repair Versus High Tibial Osteotomy for Medial Meniscus Posterior Root Tears (Root Tears)

Medial Mensical Tear

Egypt
Hartford Hospital

Recruiting

Liposomal Bupivacaine/Bupivacaine in RS Blocks vs. Ropivacaine in RS Blocks And Catheters (EXODUS)

Aortic Aneurysm, Abdominal | Aortic Diseases | Aortoiliac Occlusive Disease | Abdominal Aortic Occlusion

United States
Michigan State University

Not yet recruiting

MOSAIC (MOthers' AdvocateS In the Community) for Pregnant Women and Mothers of Children Under 5 With Experience of Intimate Partner Violence (MOSAIC Plus) Open Trial (MOSAIC Plus OT)

Depression | Intimate Partner Violence | Posttraumatic Stress Symptom
Mineralys Therapeutics Inc.

Recruiting

Open-Label Extension Study to Assess Safety, Efficacy, and Tolerability of Lorundrostat in Subjects With Uncontrolled Hypertension

Hypertension

United States, Puerto Rico
National Taiwan University Hospital

Recruiting

Robotic Versus Laparoscopy NOSE for Stage I-III Left-sided Colon Cancer

Colorectal Cancer

Taiwan
Astellas Pharma Global Development, Inc.

Recruiting

A Study of Roxadustat to Treat Anemia in Children and Teenagers With Chronic Kidney Disease

Chronic Kidney Disease | Renal Anemia

Romania, Spain, Belgium, Germany, Norway, Slovakia, Denmark, Czechia
Ji Xunming,MD,PhD
Beijing Friendship Hospital; Shandong Provincial Hospital; Beijing Tongren Hospital and other collaborators

Recruiting

Normobaric Hyperoxia Combined With Intravenous Thrombolysis for Acute Ischemic Stroke：Longterm Outcome (OPENS-3L)

Acute Ischemic Stroke

China
University of Washington
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

Reopening Schools Safely and Educating Youth Research- Early Learning Ancillary Study

Absenteeism

United States
Zhongshan Ophthalmic Center, Sun Yat-sen University

Not yet recruiting

Effect of Peripapillary Atrophy to Diagnose Glaucoma in High Myopia

Eye Diseases | Refractive Errors | Myopia | Glaucoma, Primary Open Angle | Peripapillary Atrophy

China
Ji Xunming,MD,PhD
The First Affiliated Hospital of Anhui Medical University; Beijing Friendship... and other collaborators

Recruiting

Normobaric Hyperoxia Combined With Intravenous Thrombolysis for Acute Ischemic Stroke (OPENS-3)

Acute Ischemic Stroke

China
Royal Surrey County Hospital NHS Foundation Trust

Recruiting

MIRRORS-RCT Pilot: Role of Robotic Interval Cytoreductive Surgery for Advanced Ovarian Cancer (MIRRORS-RCTP)

Fallopian Tube Neoplasms | Ovarian Cancer | Fallopian Tube Cancer | Peritoneal Cancer | Ovarian Neoplasm | Ovarian Neoplasm Epithelial

United Kingdom
East Lancashire Hospitals NHS Trust

Not yet recruiting

The MANTRA Trial (MANdibular TRauma and Antibiotic Use) (MANTRA)

Mandible Fracture | Post-operative Antibiotics

United Kingdom
Yuzuncu Yıl University

Recruiting

Effects of Serratus Anterior Plan Block (SAP) and Pectoralis Blocks (PECS I-II) After Open Heart Surgery

Postoperative Complications | Postoperative Pain | Side Effect

Turkey
Lady Hardinge Medical College

Recruiting

Modified Atkins Diet Versus Topiramate In Children With Epileptic Spasms Refractory To Hormonal Treatment: A Randomized Open-Label Study (TOPAMAD)

Epileptic Spasms, Failed Hormonal Therapy

India
InSight Vision Center Medical Group, Inc

Recruiting

Hydrus Microstent as a Quality of Life Consideration

Open Angle Glaucoma

United States
University of California, Los Angeles
PoloMar Health LLC

Not yet recruiting

An Open-Label, Single-Arm Clinical Trial Evaluating the Safety and Efficacy of Amisulpride in Treating Patients With Schizophrenia and Schizoaffective Disorder Who Have Treatment-Resistant Positive Symptoms (AmisulprideTRS)

Schizophrenia, Treatment-Resistant
Dartmouth-Hitchcock Medical Center
Patient-Centered Outcomes Research Institute; Beth Israel Deaconess Medical... and other collaborators

Recruiting

Comparing Healthcare Visit Recording and Open Notes to Improve Chronic iLlness Care Experience in Older Adults (CHRONICLE)

Hypertension | Diabetes Mellitus

United States
Forma Therapeutics, Inc.
Novo Nordisk A/S

Recruiting

A Phase 2 Open-label Study to Evaluate the Activity of Etavopivat on Transcranial Doppler Velocities in Pediatric Patients With Sickle Cell Disease Who Are at Increased Risk for Primary Stroke

Sickle Cell Disease

Nigeria, India, Oman
Rhode Island Hospital

Not yet recruiting

Optimizing Open Label Placebo Rationales

Chronic Pain
Ridge Eye Care
Alcon Research

Recruiting

Clinical Outcomes in Cataract Surgery With OMNI Canaloplasty vs Cataract Surgery With OMNI Canaloplasty and Hydrus Stent

Glaucoma, Open-Angle

United States
Washington University School of Medicine
United States Department of Agriculture (USDA); Project Peanut Butter; Ministry... and other collaborators

Recruiting

Improving Cognition and Gestational Duration With Targeted Nutrition (COGENT)

Postpartum Depression | Preterm Birth | Child Development | Malnutrition in Pregnancy | Antepartum Depression

Sierra Leone
Shanghai 6th People's Hospital

Recruiting

A Single-arm, Open-label, Single-center Prospective Study of Fruquintinib Combined With Envafolimab in the Treatment of Advanced or Unresectable Locally Advanced Bone and Soft Tissue Sarcoma

Advanced or Unresectable Locally Advanced Bone and Soft Tissue Sarcoma

China
Tianjin Medical University Cancer Institute and...

Recruiting

Continuation of Serplulimab Plus Chemotherapy After First Progression in Advanced Gastric or Gastro-oesophageal Junction Adenocarcinoma: an Open-label, Randomised Phase II Trial

Gastric Cancer (GC) Gastroesophageal Junction Cancer (GEJ)

China
The University of Hong Kong
Icare Finland Oy

Not yet recruiting

Impact of Home Intraocular Pressure Telemonitoring on Intraocular Pressure Control and Glaucoma Progression

Primary Open Angle Glaucoma | Glaucoma | Intraocular Pressure
Maimonides Medical Center
Foundation for Prader-Willi Research

Recruiting

Impact of Bright Light Therapy on Prader-Willi Syndrome (PWS-LT)

Body Weight | Hyperphagia | Prader-Willi Syndrome | Mood | Behavior | Excessive Daytime Sleepiness

United States
Novartis Pharmaceuticals

Recruiting

An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC. (PSMA-DC)

Oligometastatic Prostate Cancer (OMPC)

Japan, Singapore, Canada, Israel, Switzerland, Australia, United States
Mohamed Gamal Thabet

Recruiting

Comparative Study Between Arthroscopic Versus Open Surgical Discopexy for Treatment of Temporomandibular Joint Anterior Disc Displacement Without Reduction (RCT)

Efficacy of TMJ Arthroscopy

Egypt
Nicox Ophthalmics, Inc.

Recruiting

Aqueous Humor Dynamics of NCX 470 Ophthalmic Solution (Whistler)

Open Angle Glaucoma

United States
Peking Union Medical College Hospital

Recruiting

Cross-sectional Case and Control Study on Quality of Life, Appearance and Functions in PTC Via Different Surgical Approach

Papillary Thyroid Carcinoma | Thyroid Cancer

China
Chulalongkorn University
HIV-NAT, Thai Red Cross - AIDS Research Centre; Chula Clinical Research Center...

Recruiting

Immunogenicity and Safety of Comvigen (Bivalent) Vaccine

Safety of a Single Dose of COMVIGEN Vaccine | Reactogenicity of a Single Dose of COMVIGEN Vaccine | Immunogenicity of a Single Dose of COMVIGEN Vaccine | Safety of a Single Dose of BIVALENT Pfizer/BNT Vaccine | Reactogenicity of a Single Dose of BIVALENT Pfizer/BNT Vaccine | Immunogenicity...

Thailand
University of Milano Bicocca

Not yet recruiting

Phase 2, Open-label, Single-arm Study on the Use of Metformin as Adjunctive Therapy in High-grade Glioma

Malignancies | Glioblastoma, IDH-wildtype | Metformin

Italy
Montefiore Medical Center
National Institute of Allergy and Infectious Diseases (NIAID)

Recruiting

Open Trial of Trauma-focused Psychodynamic Psychotherapy for People Living With HIV and PTSD (TFPP-PLWH)

HIV | Post Traumatic Stress Disorder

United States
Aga Khan University

Recruiting

Effect of Methylprednisolone on Systemic Inflammatory Response During Pediatric Congenital Open-Heart Surgery

Cardiopulmonary Bypass | Cyanotic Heart Disease

Pakistan
Flare Therapeutics Inc.

Recruiting

A Study of FX-909 in Patients With Advanced Solid Malignancies, Including Advanced Urothelial Carcinoma

Advanced Solid Tumors Cancer | Advanced Urothelial Carcinoma | Open Label | Oral Drug Administration

United States
University of Nove de Julho

Not yet recruiting

Preventive Effect of Photobiomodulation in the Postoperative Period of Extractions of Retained Lower Third Molars

Molar, Third | Photobiomodulation
The Cleveland Clinic

Recruiting

Preoperative Weight Loss for Open Abdominal Wall Reconstruction

Abdominal Wall Hernia

United States
AstraZeneca

Recruiting

Determine Effectiveness of Anifrolumab In SYstemic Sclerosis (DAISY) (DAISY)

Systemic Sclerosis | Scleroderma

United States, Italy, Mexico, Hungary, Belgium, Spain, Japan, Poland, Germany, China, India, Korea, Republic of, Vietnam, France, Austria, Israel, Canada, Turkey, Netherlands, United Kingdom, South Africa, Romania
Immanuel Kant Baltic Federal University

Recruiting

Factors Influencing the Results of Treatment in Patients With Hernias of Various Localizations

Chronic Pain | Inguinal Hernia | Ventral Hernia | Umbilical Hernia | Femoral Hernia | Acute Post Operative Pain | Recrrence Rate

Russian Federation
Mayo Clinic

Recruiting

A Study of FRaDCs for Ovarian Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Recurrent Ovarian High Grade Serous Adenocarcinoma | Fallopian Tube Carcinosarcoma | Primary Peritoneal Carcinosarcoma | Recurrent Fallopian Tube Clear Cell Adenocarcinoma | Recurrent Fallopian... and other conditions

United States
D. Western Therapeutics Institute, Inc.

Recruiting

Study of Safety and Efficacy of H-1337 in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Glaucoma Open-Angle Primary

United States
University of Derby
University of Exeter; University Hospitals of Derby and Burton NHS Foundation... and other collaborators

Not yet recruiting

An Open-label, Clinical Feasibility Study of the Efficacy of Remdesivir for Long-COVID. (ERASE-LC)

COVID-19 | SARS-CoV-2 Infection

United Kingdom
National Institute of Allergy and Infectious Diseases...

Recruiting

Study of the Plasmodium Vivax Transmission-blocking Vaccine Pvs230D1-EPA/Matrix-M to Assess Safety, Immunogenicity, and Transmission-blocking Activity in Healthy Malaria-naive Adults

Malaria

United States
Semmelweis University

Recruiting

Application of Surgical Templates in the Surgical Exposure of Impacted Canines

Impacted Tooth

Hungary
Servier Affaires Médicales

Recruiting

An Open-label Phase 3b Study of Ivosidenib in Combination With Azacitidine in Adult Patients Newly Diagnosed With IDH1m Acute Myeloid Leukemia (AML) Ineligible for Intensive Induction Chemotherapy.

Acute Myeloid Leukemia (AML)

Netherlands, Italy, Austria, France

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