Search clinical trials for: phase I study

Total 495979 results

Enanta Pharmaceuticals, Inc
hVIVO Services Limited

Recruiting

A Controlled Phase 2a Study to Evaluate the Efficacy of EDP-323 Against Respiratory Syncytial Virus Infection in a Virus Challenge Model

RSV Infection

United Kingdom
M.D. Anderson Cancer Center

Recruiting

Phase II Randomized-registry Embedded Study of Lymphoscintigraphy for Oropharyngeal Neoplasms to Enable Risk-adapted Nodal Guidance for Robotic Surgery and/or Radiotherapy (LONE-RANGR2)

Oropharyngeal Neoplasms | Robotic Surgery and/or Radiotherapy | Lymphoscintigraphy

United States
Revolution Medicines, Inc.

Recruiting

Study of RAS(ON) Inhibitor Combinations in Patients With Advanced RAS-mutated NSCLC

Non-Small Cell Lung Cancer, NSCLC | KRAS, NRAS, HRAS-mutated NSCLC | KRAS G12C-mutated Solid Tumors, Lung Cancer | Lung Cancer Stage IV, Advanced Solid Tumor, Cancer

United States
Zai Lab (Hong Kong), Ltd.

Recruiting

A Phase 3b Randomized, Double-blind, Multi-center Study to Compare the Safety and Efficacy of Omadacycline to Moxifloxacin for Treating Adult Subjects With CABP (public)

Community-acquired Bacterial Pneumonia

China
Yisheng Biopharma (Singapore) Pte. Ltd.

Not yet recruiting

A Phase I, The Study to Evaluate the Safety, Immunogenicity and Efficacy of YS-HBV-002

Chronic Hepatitis b
Servier Bio-Innovation LLC
Regeneron Pharmaceuticals; Institut de Recherches Internationales Servier

Not yet recruiting

Phase 1b/2 Platform Study of Select Immunotherapy Combinations in Participants With Advanced Non-small Cell Lung Cancer (NSCLC)

Non-small Cell Lung Cancer (NSCLC)

Hong Kong, United States, Australia
Terns, Inc.

Not yet recruiting

CARDINAL- A Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of TERN-701 in Participants With Chronic Myeloid Leukemia

Chronic Myeloid Leukemia | Chronic Myeloid Leukemia, Chronic Phase

United States
Apellis Pharmaceuticals, Inc.

Recruiting

A Prospective, Multicenter, Open-Label, Observational Phase 4 Study to Evaluate Real-World Safety, Tolerability, and Treatment Patterns of Pegcetacoplan (Syfovre) in Patients With Geographic Atrophy Secondary to Age-Related Macular Degeneration

Geographic Atrophy

United States
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Not yet recruiting

Retifanlimab With Bevacizumab and Hypofractionated Radiotherapy for the Treatment of Recurrent Glioblastoma

Recurrent Glioblastoma | Recurrent WHO Grade 4 Glioma

United States
National Cancer Center, Korea

Recruiting

A Randomized Phase II Study of LAZE rtiNib Alone Versus Lazertinib Plus bevaCizumab for NSCLC With EGFR + & Smoker

Lazertinib

Korea, Republic of
JMackem Co., Ltd
Seoul National University Hospital

Recruiting

A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics After Oral Administration of AJH-2947 in Healthy Korean and/or Caucasian Adult Male Subjects

Diabetic Neuropathies | Neuropathic Pain | Post Herpetic Neuralgia

Korea, Republic of
GlaxoSmithKline

Not yet recruiting

A Study for GSK3862995B in Healthy Participants and Participants With Chronic Obstructive Pulmonary Disease

Pulmonary Disease, Chronic Obstructive

United Kingdom
Hinova Pharmaceuticals Inc.

Recruiting

A Phase I Study to Assess the Safety, Pharmacokinetics, and Anti-Tumor Activity of Oral HP518 in mCRPC Patients

Metastatic Castration-resistant Prostate Cancer

China
Vertex Pharmaceuticals Incorporated

Recruiting

A Phase 1, First-in-human Study of VX-828

Cystic Fibrosis

United States
Telios Pharma, Inc.

Recruiting

A Study of TL-925 for the Treatment of Allergic Conjunctivitis

Allergic Conjunctivitis

United States
Qilu Pharmaceutical Co., Ltd.

Recruiting

A Phase 3 Clinical Study of QLM3004 in Delaying Myopia in Children

Myopia

China
Altesa Biosciences, Inc.
Virtus Respiratory Research

Recruiting

RCT of Vapendavir in Patients With COPD and Human Rhinovirus/Enterovirus Upper Respiratory Infection

Infections | Virus Diseases | Respiratory Tract Infections | Respiratory Tract Diseases | Lung Diseases | Pulmonary Disease, Chronic Obstructive | Enterovirus Infections | Copd | Pulmonary Disease | Respiratory Disease | Respiratory Complication | Upper Respiratory Tract Infections | Respiratory Viral Infection | ... and other conditions

United Kingdom
Talphera, Inc

Not yet recruiting

Nafamostat Efficacy in Phase 3 Registrational CRRT Study (NEPHRO)

Acute Kidney Injury
National Cancer Institute (NCI)

Recruiting

Phase I/II Study of the Combination Immunotherapy Regimen: SX-682, TriAdeno Vaccine, Retifanlimab and IL-15 Agonist N-803 (STAR15) for Metastatic Colorectal Cancer (mCRC)

Metastatic Colorectal Cancer

United States
Eli Lilly and Company

Recruiting

A Study of LY3971297 in Healthy Participants and Participants With Obesity and Hypertension

Hypertension | Healthy | Obesity

United States, Singapore
Dongguan HEC Biopharmaceutical R&D Co., Ltd.

Recruiting

Phase 2 Study of HEC88473 Injection in Subjects With Type 2 Diabetes Mellitus

Type 2 Diabetes

China
Fusion Pharmaceuticals Inc.
AstraZeneca

Not yet recruiting

A Phase 1, Dose-escalation Study of [225Ac]-FPI-2068 in Adult Patients With Advanced Solid Tumours

Advanced Solid Tumor | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Pancreatic Ductal Adenocarcinoma | Metastatic Colorectal Carcinoma

United States, Canada
National Institute of Allergy and Infectious Diseases...

Recruiting

Safety Study of SLV213 for the Treatment of COVID-19.

COVID-19

United States
BrodenBio Co., Ltd.

Recruiting

A Phase 1 Study of BB3008 in Participants With Advanced Solid Tumors

Advanced Solid Tumor

China
Shanghai Ming Ju Biotechnology Co., Ltd.

Recruiting

A Phase 1, Single-arm, Open-label, Dose-escalation Study of JWATM204 as T Cell-targeted Immunotherapy in the Treatment Amongst Subjects With Advanced Hepatocellular Carcinoma

Liver Carcinoma | Hepatic Cell Carcinoma

China
University of Pennsylvania

Recruiting

Study of Home-Embedded Palliative Care for Hemodialysis- (and Peritoneal-) Dependent End-Stage Renal Disease (SHEPHERD 2)

End-Stage Renal Disease

United States
Vergent Bioscience, Inc.

Recruiting

Phase 2B Safety and Efficacy Study of VGT-309 in Subjects With Cancer in the Lung. (VISUALIZE)

Lung Cancer | Lung Metastases

United States, Australia
Constant Therapeutics LLC

Recruiting

Phase 2 Study of TXA127 in Post-ischemic Stroke Patients

Ischemic Stroke

Israel
University of California, San Francisco
National Institute of Mental Health (NIMH); Stanford University

Recruiting

Better Sleep Study

Depression in Adolescence | Delayed Sleep Phase

United States
Bivision Pharmaceuticals, Inc.

Recruiting

Phase 1/2 Clinical Study of Lutetium Lu 177 JH020002 Injection in Patients With Advanced Prostate Cancer

Prostate Cancer

China
A2A Pharmaceuticals Inc.

Recruiting

A First-In-Human, Phase 1 Study Evaluating Oral TACC3 PPI Inhibitor, AO-252, in Advanced Solid Tumors

Triple Negative Breast Cancer | Endometrial Cancer | High Grade Serous Ovarian Cancer

United States
Nektar Therapeutics

Recruiting

A Phase 2b Study to Evaluate Rezpegaldesleukin (Rezpeg) in the Treatment of Adult Patients With Moderate-to-Severe Atopic Dermatitis (REZOLVE-AD)

Moderate to Severe Atopic Dermatitis

Spain, Czechia, United States, Australia, Croatia, Bulgaria, Poland, Canada, Germany, Hungary
Shanghai Junshi Bioscience Co., Ltd.
Sponsor GmbH

Not yet recruiting

A Phase Ib/II Study Of JS015 Combination Therapy in Advanced Solid Tumors

Advanced Solid Tumor

China
Novartis Pharmaceuticals

Recruiting

Phase 3 Extension Study to Evaluate Long-term Safety of Ianalumab in Participants With Systemic Lupus Erythematosus (SIRIUS-SLE Extension). (SIRIUS-SLE LTE)

Systemic Lupus Erythematosus

Spain
Lantern Pharma Inc.

Recruiting

A Study of LP-284 in Relapsed or Refractory Lymphomas and Solid Tumors

Advanced Solid Tumor | Relapsed or Refractory Lymphomas

United States
Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Not yet recruiting

Phase I Study of SHR-2022 Injection in the Treatment of Patients With Advanced Malignant Tumors

Advanced Malignant Cancer
Intellia Therapeutics
Regeneron Pharmaceuticals

Recruiting

MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)

Transthyretin Amyloidosis (ATTR) With Cardiomyopathy

United States, Australia, United Kingdom, New Zealand, Canada
Zero Point Five Therapeutics

Not yet recruiting

Phase 3, Multi-center, Prospective, Randomized, Double-blind, Placebo- Controlled Study to Evaluate the Effectiveness and Safety of ZP5-9676 for the Treatment of Soil Transmitted Helminthiasis (STH)

Soil-Transmitted Helminthiasis (STH)

Brazil, Ghana
3D Medicines (Sichuan) Co., Ltd.

Recruiting

Phase III Study of Envafolimab Versus Placebo Plus Chemotherapy in Resectable Stage III NSCLC

Non-small Cell Lung Cancer

China
Xi'an Xintong Pharmaceutical Research Co.,Ltd.
The First Hospital of Jilin University

Recruiting

A Phase Ic/IIb Study to Evaluate the Efficacy，Safety and Pharmacokinetics of HST in Patients With CHB (HTS)

Pharmacokinetics | Efficacy | Safety

China
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Phase I Study of Autologous Tumor-Draining Lymph Node-Derived Lymphocytes for Advanced HER2-Negative Breast Cancer

Breast Neoplasms

China
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Phase I Study of Autologous Tumor-Draining Lymph Node-Derived Lymphocytes as Neoadjuvant Therapy for HER2-Negative Breast Cancer

Breast Neoplasms

China
Trishula Therapeutics, Inc.
AbbVie

Recruiting

Phase 2 Study of TTX-030 and Chemotherapy With or Without Budigalimab for 1L mPDAC Patients

Pancreatic Cancer

United States, Korea, Republic of
Shanghai Juncell Therapeutics

Recruiting

A Phase Ⅰb Study on Autologous GC101 TIL Injection for the Treatment of Advanced Melanoma (MIZAR-002) (MIZAR-002)

Melanoma | Efficacy | Adverse Drug Event | Safety | Tumor Infiltrating Lymphocytes

China
Cabaletta Bio

Recruiting

RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus

Systemic Lupus Erythematosus | Lupus Nephritis

United States
Guangzhou Bio-gene Technology Co., Ltd

Recruiting

Phase I Clinical Study: BG1805 Injection in the Treatment of Relapsed or Refractory Acute Myeloid Leukemia

Leukemia, Myeloid, Acute

China
Sirius Therapeutics Co., Ltd.

Recruiting

A Phase 1 Study to Evaluate the Safety, Tolerability, PK/PD of SRSD107 in Healthy Participants

Thrombosis

Australia
Shanghai Henlius Biotech

Recruiting

A Phase I Study to Evaluate the Safety, Tolerability, and PK of HLX43 in Advanced/Metastatic Solid Tumors

Advanced Solid Tumor

China
Angitia Biopharmaceuticals

Recruiting

A Phase 3 Study of AGA111 in Patients With Degenerative Disc Disease Undergoing Lumbar Interbody Fusion

Degenerative Disc Disease

China
The University of Hong Kong

Recruiting

KeySteps@JC Phase Two Study

Lifestyle Modification

Hong Kong

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