Search clinical trials for: primary progressive aphasia

Total 18632 results

Mayo Clinic
National Cancer Institute (NCI)

Completed

Recombinant Measles Virus Vaccine Therapy and Oncolytic Virus Therapy in Treating Patients With Progressive, Recurrent, or Refractory Ovarian Epithelial Cancer or Primary Peritoneal Cancer

Ovarian Cancer | Primary Peritoneal Cavity Cancer

United States
Hoffmann-La Roche

Completed

A Study of Ocrelizumab in Participants With Primary Progressive Multiple Sclerosis

Multiple Sclerosis, Primary Progressive

United States, Canada, Australia, Hungary, Brazil, Finland, Italy, Germany, Romania, Lithuania, France, Greece, Peru, Portugal, Spain, Switzerland, Bulgaria, Ukraine, Israel, Poland, Austria, New Zealand, Netherlands, Belgium, Mexico, United... and more
NYU Langone Health
National Heart, Lung, and Blood Institute (NHLBI); Center for Advancing Point...

Completed

RELAXaHEAD for Headache Patients (Phase II)

Multiple Sclerosis | Migraine | Insomnia | Headache

United States
ARCAGY/ GINECO GROUP
Hoffmann-La Roche

Active, not recruiting

ATALANTE: Atezolizumab vs Placebo Phase III Study in Late Relapse Ovarian Cancer Treated With Chemotherapy+Bevacizumab (ATALANTE)

Ovarian Cancer

Spain, Belgium, France, Germany, Austria, Czechia, Israel
University of Nebraska
National Cancer Institute (NCI)

Completed

Capecitabine, Epirubicin, and Carboplatin in Treating Patients With Progressive, Unresectable, or Metastatic Cancer

Gastric Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Liver Cancer | Gallbladder Cancer | Extrahepatic Bile Duct Cancer

United States
Stealth BioTherapeutics Inc.

Active, not recruiting

Study to Evaluate Efficacy and Safety of Elamipretide in Subjects With Primary Mitochondrial Disease From Nuclear DNA Mutations (nPMD) (NuPower)

Mitochondrial Diseases | Mitochondrial Myopathies | Mitochondrial Complex I Deficiency | Mitochondrial Pathology | Mitochondrial DNA Depletion | Mitochondrial DNA Mutation | Mitochondrial DNA Deletion | Mitochondrial Metabolism Defect

Spain, United States, Italy, Netherlands, Australia, Germany, Hungary, New Zealand, Norway, United Kingdom
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Niraparib and Copanlisib in Treating Patients With Recurrent Endometrial, Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Progressive Disease | Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Recurrent Endometrial Carcinoma | Endometrial Adenocarcinoma | Primary Peritoneal High Grade Serous Adenocarcinoma | Platinum-Resistant Ovarian Carcinoma | High Grade Ovarian... and other conditions

United States
Mapi Pharma Ltd.

Active, not recruiting

Safety and Efficacy of Monthly Long-acting IM Injection of 25mg or 40 mg GA Depot in Subjects With PPMS

Primary Progressive Multiple Sclerosis

Israel, Moldova, Republic of
Sunnybrook Health Sciences Centre
Fondazione Italiana Sclerosi Multipla; University of Alabama at Birmingham; University... and other collaborators

Completed

Improving Cognition in People With Progressive Multiple Sclerosis Using Aerobic Exercise and Cognitive Rehabilitation

Cognitive Impairment | Multiple Sclerosis, Primary Progressive

Canada
Regeneron Pharmaceuticals
Sanofi

Active, not recruiting

Registry of Asthma Patients Initiating DUPIXENT® (RAPID)

Asthma

United States, United Kingdom, Canada, France, Puerto Rico, Japan, Spain, Denmark, Italy, Sweden
GE Healthcare
PPD

Completed

A Study to Evaluate the Diagnostic Efficacy of DaTSCAN™ Ioflupane (123I) Injection in Single Photon Emission Computed Tomography (SPECT) for the Diagnosis of Parkinsonian Syndrome (PS) in Chinese Patients

Essential Tremor | Multiple System Atrophy (MSA) | Parkinsonian Syndrome | Parkinson Disease(PD) | Progressive Supranuclear Palsy (PSP)

China
Lawson Health Research Institute

Active, not recruiting

Stereotactic Radiotherapy for Oligo-Progressive Metastatic Cancer (The STOP Trial)

Metastatic Cancer

Canada
University of Nebraska

Terminated

Sulfation of Bile Acids as a Biomarker for Hepatobiliary Diseases

Hepatobiliary Diseases

United States
Bavarian Nordic

Completed

MVA-BN-RSV Vaccine Trial

Respiratory Syncytial Virus Infections

United States, Germany
Genentech, Inc.

Completed

Study to Explore the Mechanism of Action of Ocrelizumab and B-Cell Biology in Participants With Relapsing Multiple Sclerosis (RMS) or Primary Progressive Multiple Sclerosis (PPMS)

Multiple Sclerosis, Primary Progressive | Relapsing Multiple Sclerorsis

United States, Germany, Canada, Sweden
University of Minnesota
Mallinckrodt

Terminated

ACTH in Progressive Forms of MS

Primary Progressive Multiple Sclerosis | Secondary Progressive Multiple Sclerosis | Progressive Relapsing Multiple Sclerosis

United States
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Suspended

3'-Deoxy-3'-[18F] Fluorothymidine PET Imaging in Patients With Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Brain and Central Nervous System Tumors | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Lymphoproliferative Disorder | Myelodysplastic/Myeloproliferative Neoplasms

United States
Ipsen

Terminated

rhGH and rhIGF-1 Combination Therapy in Children With Short Stature Associated With IGF-1 Deficiency

Insulin-like Growth Factor-1 Deficiency

United States
Johns Hopkins University
United States Department of Defense

Completed

Intranasal Insulin for Improving Cognitive Function in Multiple Sclerosis

Multiple Sclerosis, Relapsing-Remitting | Multiple Sclerosis, Secondary Progressive | Multiple Sclerosis, Primary Progressive

United States
Regeneron Pharmaceuticals
Teva Pharmaceutical Industries, Ltd.

Completed

Study to Determine the Safety and the Efficacy of Fasinumab Compared to Placebo and Nonsteroidal Anti-inflammatory Drugs (NSAIDs) for Treatment of Adults With Pain From Osteoarthritis of the Knee or Hip (FACT OA2)

Osteoarthritis, Knee | Osteoarthritis, Hip

United States
Pfizer

Completed

Clostridium Difficile Vaccine Efficacy Trial (Clover)

Clostridium Difficile Infection

United States, Spain, Belgium, Taiwan, Japan, Portugal, Colombia, Korea, Republic of, Poland, Australia, Germany, Canada, Argentina, Bulgaria, Chile, Czechia, Finland, France, Hungary, Peru, Slovakia, Sweden, United Kingdom
Riphah International University

Completed

Breathing Exercises With And Without Aerobic Training In Patients With Postural Orthostatic Tachycardia Syndrome

Postural Orthostatic Tachycardia Syndrome

Pakistan
Pfizer

Completed

A 12-WEEK TITRATE STUDY TO EVALUATE SAFETY, TOLERABILITY AND PHARMACODYNAMICS OF PF-06882961 IN ADULTS WITH TYPE 2 DIABETES MELLITUS AND IN NON-DIABETIC ADULTS WITH OBESITY

Obesity | Diabetes

United States
Kowa Research Institute, Inc.

Completed

Study to Evaluate the Efficacy and Safety of K-877 in Adult Patients With Fasting High Triglyceride Levels and Normal Renal Function

Severe Hypertriglyceridemia

United States, Hungary, Belarus, Bulgaria, Czechia, Georgia, Poland, Russian Federation, Ukraine
Oryx GmbH & Co. KG

Completed

Parvovirus H-1 (ParvOryx) in Patients With Progressive Primary or Recurrent Glioblastoma Multiforme. (ParvOryx01)

Glioblastoma Multiforme

Germany
University of South Florida
Genentech, Inc.

Active, not recruiting

Upper Extremity Function in Multiple Sclerosis Patients With Advanced Disability Treated With Ocrevus

Pathologic Processes | Nervous System Diseases | Immune System Diseases | Multiple Sclerosis | Demyelinating Diseases | Autoimmune Diseases | Relapsing Remitting Multiple Sclerosis | Primary Progressive Multiple Sclerosis

United States
Kowa Research Institute, Inc.

Completed

Study to Evaluate the Efficacy and Safety of K-877 in Adult Patients With Fasting High Triglyceride Levels and Mild or Moderate Renal Impairment

Severe Hypertriglyceridemia

United States, Czechia, Belarus, Hungary, Russian Federation, Poland, Bulgaria, Georgia, Ukraine
Assistance Publique - Hôpitaux de Paris

Completed

Imaging of Intracerebral Inflammation in MS (INFLASEP)

Multiple Sclerosis, Relapsing-Remitting | Multiple Sclerosis, Secondary Progressive | Multiple Sclerosis, Primary Progressive

France
Columbia University
Biogen; ALS Association

Completed

Genomic Translation for Amyotrophic Lateral Sclerosis Care (GTAC)

ALS

United States, United Kingdom
University Hospital, Akershus
Oslo University Hospital; University Hospital of North Norway; University of... and other collaborators

Active, not recruiting

NAD Supplementation to Prevent Progressive Neurological Disease in Ataxia Telangiectasia

Ataxia Telangiectasia

Norway
Saccadous, Inc.
Barrow Neurological Institute; Dignity Health

Completed

Complex Eye Movements in Parkinson's Disease and Related Movement Disorders

Parkinson Disease | Parkinsonian Disorders | Corticobasal Degeneration | Progressive Supranuclear Palsy | Huntington Disease | Essential Tremor | Parkinson's Disease and Parkinsonism | Vascular Parkinsonism | Parkinsonian Syndrome | Multiple System Atrophy, Parkinson Variant

United States
National Cancer Institute (NCI)

Completed

Pomalidomide in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors

Neurofibromatosis Type 1 | Recurrent Primary Central Nervous System Neoplasm | Refractory Primary Central Nervous System Neoplasm | Recurrent Childhood Brain Stem Glioma | Recurrent Childhood Visual Pathway Glioma

United States
Somogy Megyei Kaposi Mór Teaching Hospital

Completed

Follow-up Study of the Effectiveness of Virtual Reality Therapy in MS Patients

Multiple Sclerosis, Chronic Progressive | Multiple Sclerosis, Primary Progressive

Hungary
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

A Phase 2 Clinical Study in Subjects With Primary Progressive Multiple Sclerosis to Assess the Efficacy, Safety and Tolerability of Two Oral Doses of Laquinimod Either of 0.6 mg/Day or 1.5mg/Day (Experimental Drug) as Compared to Placebo (ARPEGGIO)

Primary Progressive Multiple Sclerosis

United States, Canada, Germany, Italy, Netherlands, Poland, Russian Federation, Spain, Ukraine, United Kingdom
Tiziana Life Sciences LTD

Withdrawn

Phase 1b Multiple Ascending Dose Study of Foralumab in Primary and Secondary Progressive MS

Multiple Sclerosis | Primary Progressive Multiple Sclerosis | Secondary Progressive Multiple Sclerosis
Loma Linda University
H. Lundbeck A/S

Withdrawn

Safety and Efficacy of Droxidopa for Fatigue in Patients With Parkinsonism

Parkinson Disease | Multiple System Atrophy | Progressive Supranuclear Palsy

United States
Eli Lilly and Company

Completed

A Study of Tirzepatide (LY3298176) Once a Week Versus Insulin Glargine Once a Day in Participants With Type 2 Diabetes and Increased Cardiovascular Risk (SURPASS-4)

Type 2 Diabetes Mellitus

Russian Federation, United States, Puerto Rico, Australia, Taiwan, Israel, Spain, Canada, Greece, Argentina, Poland, Romania, Mexico, Slovakia, Brazil
University of Tennessee
Blanchfield Army Community Hospital

Completed

Subacute Low Back Pain in Active Duty (LBP)

Subacute Low Back Pain

United States
Abliva AB

Completed

A Phase Ia/Ib, SAD and MAD Study of of KL1333 in Healthy Subjects and Patients With Primary Mitochondrial Disease

Mitochondrial Diseases | Mitochondrial Myopathies | MELAS Syndrome | Mitochondrial Respiratory Chain Deficiencies

United Kingdom
Skane University Hospital
AC Immune SA

Completed

Optimization of Morphomer-based Alpha-synuclein PET Tracers

Parkinson Disease | Multiple System Atrophy | Corticobasal Degeneration | Progressive Supranuclear Palsy | Dementia With Lewy Bodies

Sweden
EmeraMed

Completed

Study of NBMI Treatment in Patients With Atypical Parkinsons (PSP or MSA) (EMERA006)

Multiple System Atrophy | Progressive Supranuclear Palsy

Slovenia
University of Medicine and Dentistry of New Jersey
National Cancer Institute (NCI)

Withdrawn

Collecting and Storing Blood Samples From Patients With Cancer

Lymphoma | Unspecified Childhood Solid Tumor, Protocol Specific | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Brain and Central Nervous System Tumors | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Nonmalignant Neoplasm | Lymphoproliferative Disorder and other conditions
University of Calgary

Completed

Hydroxychloroquine in Primary Progressive Multiple Sclerosis

Multiple Sclerosis, Primary Progressive

Canada
Friedemann Paul
TAIYO EUROPE

Completed

Sunphenon in Progressive Forms of Multiple Sclerosis (SUPREMES)

Multiple Sclerosis

Germany
University College Dublin

Completed

A Study of the Effectiveness of Fampridine in Improving Upper Limb Function in MS

Primary Progressive Multiple Sclerosis | Secondary Progressive Multiple Sclerosis

Ireland
Aristotle University Of Thessaloniki
Greek Alzheimer's Association and Related Disorders; Ellis-Farm, Eliama Daily...

Completed

Efficacy of Early Harvest Olive Oil in Cognition of Primary (PPMS) or Secondary (SPMS) Progressive Multiple Sclerosis

Progressive Multiple Sclerosis

Greece
University of Colorado, Denver

Completed

Defining Phenotypes of Movement Disorders :Parkinson's Plus Disorders (PD), Essential Tremor (ET), Cortical Basal Degeneration (CBD), Multiple Systems Atrophy (MSA), Magnetoencephalography. (PHENO)

Parkinson Disease | Supranuclear Palsy, Progressive | Multiple System Atrophy | Corticobasal Degeneration | Essential Tremor

United States
National Institute of Allergy and Infectious Diseases...

Completed

Idebenone for Primary Progressive Multiple Sclerosis

Multiple Sclerosis | Primary Progressive Multiple Sclerosis

United States
Mersin University

Completed

Effect of Massage and Progressive Relaxation Exercises on Primary Dysmenorrhea

Primary Dysmenorrhea

Turkey
Ospedale Generale Di Zona Moriggia-Pelascini
Ospedale di Vipiteno-Sterzing (SABES-ASDAA)

Completed

Application of Machine Learning Method in Validation of Screening Cognitive Test for Parkinsonisms (CoMDA-ML-P)

Supranuclear Palsy, Progressive | Multiple System Atrophy | Primary Parkinsonism | Secondary Vascular Parkinson Disease

Italy

Search clinical trials for: primary progressive aphasia

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