Search clinical trials for: purine metabolites

Total 2451 results

University of Zurich
Swiss National Science Foundation

Recruiting

MidregiOnal Proatrial Natriuretic Peptide to Guide SEcondary Stroke Prevention (MOSES)

Stroke, Ischemic

Spain, United Kingdom, Switzerland, Greece, Norway
Children's Oncology Group
National Cancer Institute (NCI)

Recruiting

Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

B Acute Lymphoblastic Leukemia | Central Nervous System Leukemia | Testicular Leukemia | B Lymphoblastic Lymphoma | Mixed Phenotype Acute Leukemia

United States, Canada, Australia, Puerto Rico, New Zealand
Stanford University
National Center for Complementary and Integrative Health (NCCIH)

Recruiting

Multiomic Signatures of Microbial Metabolites Following Prebiotic Fiber Supplementation

Prebiotics

United States
National Cancer Institute (NCI)

Recruiting

A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia

Down Syndrome | B Acute Lymphoblastic Leukemia | B Lymphoblastic Lymphoma

United States, Canada, Puerto Rico, Australia, New Zealand
Le Bonheur Children's Hospital

Recruiting

Preventing Acute Kidney Injury (AKI) in Pediatric Patients (AKI)

Acute Kidney Injury

United States
Chinese University of Hong Kong

Recruiting

Biobank - Investigating the Gut Microbiota, Genetics, Epigenetics and Metabolites

Inflammatory Bowel Diseases

Hong Kong
Campus Bio-Medico University

Recruiting

SAPT Versus DAPT in Incomplete Revascularization After CABG (SDAT-IRC)

Coronary Artery Disease

Italy
Beijing Anzhen Hospital

Recruiting

Genotyping GUided Antiplatelet theRapy in pAtieNts Treated With Drug Eluting stEnts (GUARANTEE)

Angina, Stable | Acute Coronary Syndrome | Drug-Eluting Stents | Genotype

China
University Hospital Inselspital, Berne

Recruiting

The Bern Heart and Brain Interaction Study - Interaction Between Brain and Heart in Acute Ischemic Stroke (BEHABIS)

Acute Stroke

Switzerland
Massachusetts General Hospital

Recruiting

Effect of Theophylline in Pseudohypoparathyroidism

PHP Ia | PHP IB | Php1C

United States
Rahul Aggarwal
AstraZeneca

Recruiting

Ceralasertib (AZD6738) Alone and in Combination With Olaparib or Durvalumab in Patients With Solid Tumors

Clear Cell Renal Cell Carcinoma | Metastatic Renal Cell Carcinoma | Endometrial Cancer | Stage III Renal Cell Cancer | Locally Advanced Malignant Solid Neoplasm | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | Metastatic Malignant Solid Neoplasm | Metastatic Urothelial Carcinoma | Stage IV... and other conditions

United States
Wills Eye

Recruiting

Caffeine Consumption in Glaucoma Patients and Healthy Subjects

Glaucoma, Primary Open Angle

United States
Nanfang Hospital, Southern Medical University

Recruiting

Evaluating the Association Between Sphingolipid Metabolites and Post-hepatectomy Liver Failure

Post-hepatectomy Liver Failure

China
Centre de Recherche de l'Institut Universitaire...

Recruiting

Short-Term Anticoagulation Versus Antiplatelet Therapy for Preventing Device Thrombosis Following Left Atrial Appendage Closure (ANDES)

Stroke | Thrombosis | Bleeding | Left Atrial Appendage Closure | TIA

Canada
Vastra Gotaland Region
Uppsala University; Gothia Forum - Center for Clinical Trial

Recruiting

Ticagrelor and ASA vs. ASA Only After Isolated Coronary Artery Bypass Grafting in Patients With Acute Coronary Syndrome (TACSI)

Acute Coronary Syndrome

Denmark, Sweden, Norway, Finland, Iceland
Faculty Hospital Kralovske Vinohrady
Charles University, Czech Republic

Recruiting

Dual Antiplatelet Therapy For Shock Patients With Acute Myocardial Infarction (DAPT-SHOCK-AMI)

Acute Myocardial Infarction | Cardiogenic Shock

Czechia, Germany, Poland, Slovakia, France
NYU Langone Health

Recruiting

A Single Center Diagnostic, Cross-sectional Study of Coronary Microvascular Dysfunction

Myocardial Ischemia | Ischemic Heart Disease | Coronary Microvascular Disease

United States
University of Southern California
National Cancer Institute (NCI)

Recruiting

Collection of Blood in Studying Metabolites in Patients With Prostate Cancer

Prostate Carcinoma

United States
The Guthrie Clinic

Recruiting

Fentanyl and Crushed Ticagrelor in Percutaneous Coronary Intervention (FACTPCI)

Percutaneous Coronary Intervention

United States
Charite University, Berlin, Germany
Stiftung Institut fuer Herzinfarktforschung; Deutsches Zentrum für Herz-Kreislauf-Forschung... and other collaborators

Recruiting

Left Atrial Appendage CLOSURE in Patients With Atrial Fibrillation Compared to Medical Therapy (CLOSURE-AF)

Atrial Fibrillation

Germany
Peking Union Medical College Hospital

Recruiting

Anti-platelet Effect of Berberine in Patients After Percutaneous Coronary Intervention (APLABE-PCI)

Coronary Artery Disease | Percutaneous Coronary Intervention

China
Assistance Publique Hopitaux De Marseille

Recruiting

TicagRelor Or Clopidogrel in Severe and Terminal Chronic Kidney Disease Patients Undergoing PERcutaneous Coronary Intervention for an Acute Coronary Syndrome. (TROUPER)

Acute Coronary Syndrome

France
University of Pittsburgh

Recruiting

Longitudinal Study of Neurodegenerative Disorders

Lysosomal Storage Diseases | Leukodystrophy | Niemann-Pick Diseases | Batten Disease | Gaucher Disease | Krabbe Disease | Alpha-Mannosidosis | Osteopetrosis | Tay-Sachs Disease | Pelizaeus-Merzbacher Disease | Sandhoff Disease | GM1 Gangliosidoses | MPS I | MPS II | Vanishing White Matter Disease | Multiple Sulfatase Deficiency... and other conditions

United States
Medical University of South Carolina

Recruiting

Pembrolizumab in Combination With Anti-platelet Therapy for Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

Head and Neck Cancer

United States
Crystal Mackall, MD

Recruiting

Phase I Dose Escalation Study of CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory B Cell Malignancies

Recurrent Adult Acute Lymphoblastic Leukemia | Recurrent Childhood Acute Lymphoblastic Leukemia | B Acute Lymphoblastic Leukemia | Philadelphia Chromosome Positive | Refractory Acute Lymphoblastic Leukemia | Minimal Residual Disease | CD19 Positive

United States
Weill Medical College of Cornell University

Recruiting

Use of Adenosine to Determine the Electrophysiological Mechanism of Premature Ventricular Contractions

Premature Ventricular Contraction (PVC)

United States
Virginia Commonwealth University
Wake Forest University

Recruiting

Myocardial Perfusion and Fibrosis in Cancer Survivors

Myocardial Fibrosis | Myocardial Injury | Chemotherapeutic Toxicity

United States
Paul Kim

Recruiting

Allograft Dysfunction in Heart Transplant

Heart Transplant Failure and Rejection

United States
Cedars-Sinai Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Whole-Heart Myocardial Blood Flow Quantification Using MRI

Coronary Artery Disease | Coronary Microvascular Disease

United States
Vanderbilt University Medical Center
Harvard University

Recruiting

Theophylline Treatment for Pseudohypoparathyroidism

Albright Hereditary Osteodystrophy | Pseudohypoparathyroidism

United States
Assistance Publique Hopitaux De Marseille

Recruiting

Vitamin D and Its Metabolites Quantification in Adipose Tissues of Obese and Non-obese Patients. (VITADOSE)

Obesity; Endocrine

France
Children's Oncology Group
National Cancer Institute (NCI); EsPhALL Network/ BFM Study Group

Recruiting

Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia | B Acute Lymphoblastic Leukemia | T Acute Lymphoblastic Leukemia | Mixed Phenotype Acute Leukemia

United States, Canada, Puerto Rico, Australia, Finland, New Zealand, Saudi Arabia, Germany, Austria, Belgium, Chile, Czechia, France, Italy, Netherlands, Sweden, Switzerland, Hong Kong, Israel
First Affiliated Hospital Xi'an Jiaotong University

Recruiting

Migraine Prophylaxis With Clopidogrel Trial

Migraine

China
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Blinatumomab, Inotuzumab Ozogamicin, and Combination Chemotherapy as Frontline Therapy in Treating Patients With B Acute Lymphoblastic Leukemia

B Acute Lymphoblastic Leukemia | B Lymphoblastic Lymphoma

United States
UMC Utrecht
National University Hospital, Singapore; Berry Consultants; University of Pittsburgh... and other collaborators

Recruiting

Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia (REMAP-CAP)

Community-acquired Pneumonia, Influenza, COVID-19

United Kingdom, United States, Canada, Australia, Netherlands, Croatia, Germany, Belgium, New Zealand, Ireland, Spain, Japan, Hungary, Colombia, India, Nepal, Pakistan, Portugal, Romania, Saudi Arabia
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Personalized NK Cell Therapy in CBT

Recurrent Hodgkin Lymphoma | Chronic Myelomonocytic Leukemia | Previously Treated Myelodysplastic Syndrome | Recurrent Adult Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Secondary Acute Myeloid Leukemia | Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Myelodysplastic Syndrome... and other conditions

United States
Yonsei University

Recruiting

Ticagrelor Monotherapy After 3 Months in the Patients Treated With New Generation Sirolimus Stent for Acute Coronary Syndrome (TICO Study)

Acute Coronary Syndrome

Korea, Republic of
National Cancer Institute (NCI)

Recruiting

Trial of the Combination of Bortezomib and Clofarabine in Adults With Relapsed Solid Tumors

Neoplasms | Myelodysplastic Syndromes | Lymphomas

United States
North American Consortium for Histiocytosis
Histiocyte Society

Recruiting

LCH-IV, International Collaborative Treatment Protocol for Children and Adolescents With Langerhans Cell Histiocytosis

Langerhans Cell Histiocytosis

United States
National Institute of Mental Health (NIMH)

Recruiting

Development of Magnetic Resonance Spectroscopic Imaging Techniques for Imaging Metabolites in Human Brain and Muscle

Healthy Volunteer | Brain Mapping

United States
University of Chicago
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Recruiting

Chicago Social Drinking Project (CSDP)

Alcoholism

United States
Stanford University

Recruiting

Sex Differences in Coronary Pathophysiology

Ischemia | Chest Pain

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Fludarabine Phosphate, Cytarabine, Filgrastim-sndz, Gemtuzumab Ozogamicin, and Idarubicin Hydrochloride in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Untreated Adult Acute Myeloid Leukemia | Myelodysplastic Syndrome With Excess Blasts | High Risk Myelodysplastic Syndrome | de Novo Myelodysplastic Syndrome | Acute Myeloid Leukemia With t(8;21); (q22; q22.1); RUNX1-RUNX1T1 | Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11 | Acute Myeloid... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Combination Chemotherapy and Nelarabine in Treating Patients With T-cell Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

T Acute Lymphoblastic Leukemia | T Lymphoblastic Lymphoma

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Suspended

211^At-BC8-B10 Before Donor Stem Cell Transplant in Treating Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndrome, or Mixed-Phenotype Acute Leukemia

Acute Myeloid Leukemia | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Chronic Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Myelodysplastic Syndrome With Excess Blasts | Recurrent Acute Lymphoblastic... and other conditions

United States
National Cancer Institute (NCI)

Active, not recruiting

Combination Chemotherapy With or Without Bortezomib in Treating Younger Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or Stage II-IV T-Cell Lymphoblastic Lymphoma

Adult T Acute Lymphoblastic Leukemia | Childhood T Acute Lymphoblastic Leukemia | Ann Arbor Stage II Adult Lymphoblastic Lymphoma | Ann Arbor Stage II Childhood Lymphoblastic Lymphoma | Ann Arbor Stage III Adult Lymphoblastic Lymphoma | Ann Arbor Stage III Childhood Lymphoblastic Lymphoma | Ann... and other conditions

United States, Canada, Australia, New Zealand
NICHD Neonatal Research Network
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Terminated

Moderately Preterm Infants With Caffeine at Home for Apnea (MoCHA) Trial (MoCHA)

Apnea of Prematurity

United States
National Cancer Institute (NCI)

Active, not recruiting

Combination Chemotherapy in Treating Young Patients With Newly Diagnosed High-Risk B Acute Lymphoblastic Leukemia and Ph-Like TKI Sensitive Mutations

B Acute Lymphoblastic Leukemia | Central Nervous System Leukemia | Testicular Leukemia | B Acute Lymphoblastic Leukemia, BCR-ABL1-Like

United States, Canada, Puerto Rico, Australia, New Zealand, Switzerland, Ireland
National Cancer Institute (NCI)

Active, not recruiting

Azacitidine and Combination Chemotherapy in Treating Infants With Acute Lymphoblastic Leukemia and KMT2A Gene Rearrangement

B Acute Lymphoblastic Leukemia | Acute Leukemia of Ambiguous Lineage | Mixed Phenotype Acute Leukemia

United States, Canada, Puerto Rico, Australia
National Cancer Institute (NCI)

Active, not recruiting

Blinatumomab in Treating Younger Patients With Relapsed B-cell Acute Lymphoblastic Leukemia

Recurrent B Acute Lymphoblastic Leukemia

United States, Canada, Puerto Rico, Australia, New Zealand

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