Search clinical trials for: safety, tolerability, PK

Total 3493 results

Peking University People's Hospital
Beijing Hospital

Recruiting

Gut Microbiota in ITP

ITP

China
Peking University People's Hospital
Shanghai Zhongshan Hospital; Qilu Hospital of Shandong University; The Affiliated... and other collaborators

Recruiting

Machine-learning Based Prediction Model in Primary Immune Thrombocytopenia

Immune Thrombocytopenia | ITP

China
Chong Kun Dang Pharmaceutical

Recruiting

A Study to Evaluate the PK, PD and Safety of CKD-382 in Healthy Subjects

GERD

Korea, Republic of
Peking University Third Hospital

Not yet recruiting

The Quality of Life and Patency Rate After Minimally Invasive Cardiac Surgery

Minimally Invasive Cardiac Surgery
XBiotech, Inc.

Recruiting

Natrunix Safety PK Study in Healthy Volunteers

Pharmacokinetics

United States
PKvitality

Recruiting

Clinical Investigation of K'Watch - Lab & Home Study (GLAM)

Diabetes

United States
Rutgers, The State University of New Jersey

Recruiting

Microbiome Derived Metabolism and Pharmacokinetics (MDM-PK)

Microbial Colonization

United States
Trethera

Recruiting

Open-Label, Dose-Escalation With Expansion to Assess the Safety, Tolerability, and PK of TRE-515 in Subjects With Solid Tumors

Oncology | Solid Tumor, Adult

United States
Duke University
Food and Drug Administration (FDA)

Recruiting

Opportunistic PK/PD Trial in Critically Ill Children (OPTIC) (OPTIC)

Critically Ill | Cardiac Disease | Children, Adult

United States
Vitaflo International, Ltd

Recruiting

Evaluation of the Express Plus Range (express plus)

Phenylketonurias | PKU | Maple Syrup Urine Disease | Homocystinuria | Glutaric Acidemia I | Hereditary Tyrosinemia

United Kingdom
Zydus Therapeutics Inc.

Recruiting

Hepatic Impairment With Cirrhosis Due to Cholestatic Liver Disease

Cirrhosis | Hepatic Impairment | Cholestatic Liver Disease

United States
Prince of Songkla University

Recruiting

PK of Meropenem in Patients on Plasma Exchange

Autoimmune Diseases

Thailand
International Partnership for Microbicides, Inc.
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

PK, Safety Study of 90-Day Use of Vaginal Rings Containing Dapivirine and Levonorgestrel

Bleeding | Pharmacokinetics | Safety Issues

United States
Hoffmann-La Roche
Genentech, Inc.

Recruiting

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants (POSTERITY)

Lupus Nephritis

United States, Brazil, Canada, France, Italy, Peru, Poland, South Africa, Spain, United Kingdom, Mexico, Russian Federation
AL-S Pharma

Recruiting

A Study to Evaluate, Safety, Tolerability, Pharmacodynamic (PD) Markers and Pharmacokinetics (PK) of AP-101 in Participants With Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis

Korea, Republic of, United States, Canada, Germany, Sweden, Belgium
Shandong TheraWisdom Biopharma Co., Ltd.

Recruiting

Safety, Tolerability, PK, PD, Immunogenicity and Efficacy of TWP-102 in Patients With Advanced Malignancies.

Advanced Malignancies

China
Qilu Hospital of Shandong University

Not yet recruiting

Prolonged Intravenous Infusion of β-lactam Antibiotics in Early Septic Patients (PROBES)

Sepsis
Respirent Pharmaceuticals Co Ltd.
Becro Ltd.

Recruiting

A Bioequivalence Study Between Fluticasone Propionate 100 mcg/Blister Oral Inhalation Powder/Respirent Pharmaceuticals vs. FLOVENT DISKUS® 100 mcg/Blister Oral Inhalation Powder /GSK in Healthy Volunteers Under Fasting Conditions

Asthma | Bioequivalence

Greece
Imperial College London

Recruiting

Evaluation of High Dose Prednisolone Pharmacokinetics in the Acute and Chronic Setting (EHD-Pred PK)

Vasculitis | Asthma | Thyroid Eye Disease | Inflammatory Disease | COPD Exacerbation Acute

United Kingdom
Swedish Orphan Biovitrum

Recruiting

Evaluate Efficacy, Safety and Tolerability, PK and PD of Emapalumab in Children and Adults With MAS in Still's or SLE (EMERALD)

Systemic Lupus Erythematosus | Macrophage Activation Syndrome | Still Disease | Secondary Hemophagocytic Lymphohistiocytosis | SJIA | AOSD | MAS

United States, Belgium, Italy, Netherlands, United Kingdom, China, France, Spain, Czechia, Canada, Sweden, Japan, Germany, Poland
Joseph L. Kuti, PharmD
Shionogi Inc.

Recruiting

Cefiderocol PK in Patients on ECMO

Sepsis

United States
Forma Therapeutics, Inc.

Recruiting

A Study of Etavopivat in Patients With Thalassemia or Sickle Cell Disease

Sickle Cell Disease | Thalassemia

United States, Lebanon, Canada
Direction Centrale du Service de Santé des Armées

Recruiting

Evaluation of the Relevance of Pharmacogenetics in the Prescription Off Antidepressants in a Military Population (PSYGEN)

Depression | Anxiety | Ptsd

France
Institut National de la Santé Et de la Recherche...
National Agency for Research on AIDS and Viral Hepatitis (ANRS)

Not yet recruiting

Impact of Malnutrition on Pharmacokinetic or Rifampicin, Isoniazid, Pyrazinamide and Ethambutol in TB-HIV Co-infected Children (TB-Speed TB-PK)

Tuberculosis | Pulmonary

Uganda, Zambia
Children's Hospital of Fudan University

Recruiting

PK/PD of Ceftazidime Avitbatan Sodium in Children With Severe Infection

Sepsis | Antibiotic Reaction

China
Children's Hospital of Fudan University

Not yet recruiting

PK/PD of Caspofungin in Children Severe Infection

Pharmacokinetics | Infection, Fungal

China
Jiangsu Simcere Pharmaceutical Co., Ltd.

Not yet recruiting

PK Study for Endostar Continuous Intravenous Infusion in NSCLC Patients With 1st-line Platinum Based Chemotherapy

Advanced or Metastatic NSCLC

China
Peking University Third Hospital

Not yet recruiting

Effect of Trimetazidine on Radiotherapy-induced Heart Damage.

Cardiotoxicity
The University of Queensland

Recruiting

Implementation of Metformin theraPy to Ease Decline of Kidney Function in Polycystic Kidney Disease (IMPEDE-PKD)

Autosomal Dominant Polycystic Kidney Disease

Australia
Hospices Civils de Lyon

Recruiting

Pharmacokinetics and Toxicodynamics of Daptomycin in Bone and Joint Infections (PKTOXDAP)

Bone and Joint Infection | Dactinomycin Adverse Reaction

France
Peking University

Recruiting

Sedation Compaired With Anesthesia With THRIVE in Endotracheal Intubation With Difficult Airways

Airway Control | Sedative, Hypnotic, or Anxiolytic Withdrawal

China
SyneuRx International (Taiwan) Corp

Recruiting

Proof of Principle Study to Evaluate the Safety, PK, Viral Shedding and Efficacy of Pentarlandir™ UPPTA for Patients With Early COVID-19

Coronavirus Disease 2019

United States
Chong Kun Dang Pharmaceutical

Not yet recruiting

Clinical Study to Investigate the PK Profiles and Safety of CKD-385 in Healthy Volunteers Under Fed Conditions

Cardiovascular Diseases

Korea, Republic of
Chong Kun Dang Pharmaceutical

Not yet recruiting

Clinical Study to Investigate the PK Profiles and Safety of CKD-385 in Healthy Volunteers Under Fasting Conditions

Cardiovascular Diseases

Korea, Republic of
Ain Shams Maternity Hospital

Recruiting

Parameters Declaring PCO Infertile Patients Either Sensitive or Resistant to Different Doses of Clomiphene Citrate.

PCO | Clomiphene Citrate | Induction of Ovulation

Egypt
Hoffmann-La Roche

Recruiting

A Study Evaluating the Efficacy and Safety of Adjuvant Atezolizumab or Placebo and Trastuzumab Emtansine for Participants With HER2-Positive Breast Cancer at High Risk of Recurrence Following Preoperative Therapy (Astefania)

Breast Cancer

Korea, Republic of, United States, Australia, China, Ukraine, Spain, United Kingdom, Turkey, Mexico, Brazil, Austria, Belgium, Denmark, Germany, Greece, Russian Federation, Taiwan, France, Kenya, New Zealand, Portugal, Thailand, Rom... and more
Harbour BioMed (Guangzhou) Co. Ltd.

Not yet recruiting

A Study to Evaluate Safety, Tolerability, PK/PD and Preliminary Efficacy of HBM4003 Combined With Anti-PD-1 Antibody

Solid Tumor
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

A Trial to Evaluate the Safety and PK Profile of HRS4800 in Healthy Subjects

Pain
Processa Pharmaceuticals

Recruiting

A Study of the Safety and PK of PCS6422 (Eniluracil) With Capecitabine in Patients With Advanced, Refractory GI Tract Tumors

Advanced Cancer | Refractory Cancer | Tumor Gastric

United States
PMG Pharm Co., Ltd

Recruiting

A Phase 3 Study to Assess the Efficacy and Safety of PK101 in Patients With Knee Osteoarthritis

Knee Osteoarthritis

Korea, Republic of
QureBio Ltd.

Recruiting

A Study of Q-1802 in Patients With Advanced Solid Tumors

Advanced Solid Tumors

China
David Lynch Foundation

Not yet recruiting

Transcendental Meditation and PTSD

Suicidal Ideation | Depressive Symptoms | Alcohol Use, Unspecified | Ptsd
Sinotau Pharmaceutical Group

Not yet recruiting

Clinical Study on PET Imaging, Distribution and PK of 89Zr-CD147 in Patients With Solid Tumors

Solid Tumor
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

Efficacy 、Safety and PK of SHR-1314 in Patients With Moderate-to-Severe Plaque Psoriasis

Moderate-to-Severe Plaque Psoriasis
Apollomics Inc.
Zhejiang CrownMab Biotech Co. Ltd

Recruiting

Study to Evaluate PK and Safety With Uproleselan Combined With Chemotherapy to Treat Chinese R/R AML Patients

Relapsed/Refractory AML

China
Kocak Farma

Recruiting

Safety and Immunogenicity of the Inactivated Koçak-19 Inaktif Adjuvanlı COVID-19 Vaccine Compared to Placebo

COVID-19 Vaccine

Turkey
The First Affiliated Hospital of Guangzhou Medical...

Recruiting

A Real-world Study of Adjuvant Therapy in Early Stage NSCLC With EGFR Mutation-Positive in China

NSCLC, Stage III | NSCLC, Stage I | NSCLC, Stage II

China
Peking University People's Hospital

Recruiting

Study on Classification Method of Indocyanine Green Lymphography Based on Deep Learning (BCRL；ICG)

Breast Cancer Related Lymphedema | Deep Learning

China
Vaccinex Inc.
Merck Sharp & Dohme LLC

Recruiting

Pepinemab in Combination With Pembrolizumab in Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck (KEYNOTE-B84)

Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck (HNSCC)

United States
University Teaching Hospital Hall in Tirol
Salzburger Landeskliniken

Recruiting

CTC Quantification During TURBT and PKVBT of Transitional Cell Carcinoma in Purging Fluid and Blood

Neoplasms | Urogenital Neoplasms | Transitional Cell Carcinoma | Circulating Tumor Cell | Urinary Bladder Neoplasm

Austria

Search clinical trials for: safety, tolerability, PK

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