Clinical Trials Sponsored by Affinium Pharmaceuticals, Ltd

Total 4439 results

Bayer
Bristol Myers Squibb Co. and Ono Pharmaceutical Co., Ltd

Active, not recruiting

A Trial to Learn Whether Regorafenib in Combination With Nivolumab Can Improve Tumor Responses and How Safe it is for Participants With Solid Tumors

Solid Tumors

United States, United Kingdom, Belgium, France, Taiwan, Japan, Italy, Korea, Republic of
Wuhan Union Hospital, China
Yichang Humanwell Pharmaceutical Co., Ltd., China

Completed

Step 1 of A Two-step Trial to Evaluate the Effectiveness and Safety of Remimazolam Besylate for Sedation in ICU Patients

Mechanically Ventilated Patients

China
Wuhan Union Hospital, China
Yichang Humanwell Pharmaceutical Co., Ltd., China

Completed

Step 2 of A Two-step Trial to Evaluate the Effectiveness and Safety of Remimazolam Besylate for Sedation in ICU Patients (ShoSReB)

Mechanical Ventilation | Sedative

China
The National Institutes of Pharmaceutical R&D Co...

Completed

A Safety, Tolerability, and Pharmacokinetic Study of NIP292 in Healthy Normal Subjects

Idiopathic Pulmonary Fibrosis

United States
Shanghai Yinnuo Pharmaceutical Technology Co.,...
Shanghai 6th People's Hospital

Completed

A Study of Supaglutide in Chinese Type 2 Diabetes Patients

Diabetes Mellitus, Type 2

China
AIO-Studien-gGmbH
Taiho Pharmaceutical Co., Ltd.; Nordic Pharma SAS

Completed

Trial of S-1 Maintenance Therapy in Metastatic Esophagogastric Cancer (MATEO)

Esophageal Neoplasms | Gastric Adenocarcinoma | Esophageal Adenocarcinoma | Gastroesophageal Junction Adenocarcinoma | Gastric Neoplasm | Unresectable, Locally Advanced or Metastatic, Adenocarcinoma of the Stomach, or of the Gastro Esophageal Junction

Germany
Shanghai JMT-Bio Inc.
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Unknown

Efficacy and Safety of JMT101 in Patients With Advanced Solid Tumor

Advanced Solid Tumor

China
Shanghai JMT-Bio Inc.
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Unknown

A Clinical Trial to Assess the Efficacy and Safety of JMT103 in Patients With Refractory HCM

Hypercalcemia of Malignancy
Peking University First Hospital
Jiangsu Wanbang Pharmaceutical Marketing Co.,Ltd.

Unknown

Efficacy of Dun Ye Guan Xin Ning Tablet in Patients With Stable Angina Pectoris

Coronary Heart Disease

China
Hospital Universitari Vall d'Hebron Research Institute
Teva Pharmaceutical Industries, Ltd.

Unknown

Contribution of Renal Function to Endothelial Dysfunction in Living Kidney Donors and Transplant Recipients (CONFUCIUS)

Chronic Kidney Disease | Endothelial Dysfunction | Disorder Related to Renal Transplantation

Spain
Beijing Tiantan Hospital
Shandong Simcere-Medgenn Bio-pharmaceutical Co., Ltd

Completed

Endostatin Study for Patients With Neurofibromatosis Type 2 (NF2) and NF2-Related Tumors (Endostatin)

Neurofibromatosis Type 2 | Vestibular Schwannoma

China
Zhejiang University
Beta Pharma, Inc.; Jiangsu Simcere Pharmaceutical Co., Ltd.

Unknown

Rh-Endostatin in Combination With Icotinib for Advanced NSCLC With EGFR Mutations

Lung Cancer

China
The Second People's Hospital of Sichuan
Biotech Pharmaceutical Co., Ltd.

Unknown

Safety and Efficacy Study of Nimotuzumab Plus Neoadjuvant and Concurrent Chemoradiotherapy to Treat Oropharynx and Hypopharynx Cancer

Hypopharyngeal Cancer | Oropharyngeal Cancer

China
Jiangsu Kanion Pharmaceutical Co., Ltd
Beijing University of Chinese Medicine

Unknown

A Clinical Trial To Evaluate Reduning Injection in the Treatment of Mild Type of Hand, Foot, and Mouth Disease

Hand, Foot and Mouth Disease

China
Qiang Fu
Yangtze River Pharmaceutical Group Co., Ltd.

Not yet recruiting

Cancer-related Fatigue in Patients With Breast Cancer Treatment With Zhengyuan Capsules (CRF)

Cancer-related Fatigue
Peking Union Medical College Hospital
Dizal (Jiangsu) Pharmaceutical Co., Ltd.

Recruiting

Assessing an Oral EGFR Inhibitor, DZD9008 in Patients With Advanced Non-small Cell Lung Cancer(NSCLC) With EGFR Mutations (WU-KONG15) (WU-KONG15)

Non Small Cell Lung Cancer

China
Yooyoung Pharmaceutical Co., Ltd.
Opera CRO, a TIGERMED Group Company

Not yet recruiting

Post Marketing Clinical Follow up Study to Evaluate the Performance and Safety of ORTHIX PLUS

Osteoarthritis, Knee | Degenerative Joint Disease of Knee
Yooyoung Pharmaceutical Co., Ltd.
Opera CRO, a TIGERMED Group Company

Not yet recruiting

Post Marketing Clinical Follow up Study to Evaluate the Performance and Safety of HYALEXO

Osteoarthritis | Degenerative Joint Disease
Peking Union Medical College Hospital
CSPC Ouyi Pharmaceutical Co., Ltd.

Recruiting

A Study of Alendronate Sodium Vitamin D3 Tablets on Knee Osteoarthritis

Knee Osteoarthritis

China
Xinqiao Hospital of Chongqing
CSPC RECOMGEN PHARMACEUTICAL (GUANGZHOU) CO.,LTD

Recruiting

Endovascular Treatment With Versus Without Intravenous rhTNK-tPA in Stroke (BRIDGE-TNK)

Stroke, Ischemic | Stroke, Acute

China
Henan Cancer Hospital
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Active, not recruiting

Paclitaxel and DDP Combined With Anlotinib in the First-line Treatment for Patients With Advanced Esophageal Squamous Cell Carcinoma（ESCC）.

Esophageal Squamous Cell Carcinoma

China
AIO-Studien-gGmbH
Taiho Pharmaceutical Co., Ltd.; Nordic Pharma SAS

Completed

Feasibility Study of Adjuvant Treatment With S-1 in Patients After R0-Resection of Adenocarcinoma of the Stomach and Esophagogastric Junction (S-1 adjuvant)

Adenocarcinoma,Stomach | Adenocarcinoma, Esophagogastric Junction

Germany
Panion & BF Biotech Inc.
Shandong Weigao Panion Pharmaceutical Co. Ltd.

Completed

Ferric Citrate for the Treatment of Hyperphosphatemia in Patients With Chronic Kidney Disease Undergoing Hemodialysis

End Stage Renal Disease | ESRD | Hyperphosphatemia

China
Shanghai JMT-Bio Inc.
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Unknown

Efficacy and Safety of JMT101 Combined With Afatinib (or Osimertinib) in Patients With Non-Small Cell Lung Cancer

Locally Advanced or Metastatic Non-Small Cell Lung Cancer

China
Ajou University School of Medicine
Dong-A Pharmaceutical Co., Ltd.

Completed

Neovascularization Induced by Mechanical Barrier disrUption and Systemic Erythropoietin in Patients With Cerebral Perfusion Deficits (NIMBUS)

Ischemic Stroke | Angiogenesis
Henan Cancer Hospital
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Unknown

Anlotinib Combined With Pemetrexed And Carboplatin as First-line Treatment in Advanced Nonsquamous NSCLC

Non-squamous Cell Non-Small Cell Lung Cancer

China
Peking University People's Hospital
Yichang Humanwell Pharmaceutical Co., Ltd., China

Unknown

Impact of CYP3A4*1G Polymorphism on Non-analgesic Effects of Fentanyl in Chinese Han Patients

Fentanyl

China
Hangzhou ACEA Pharmaceutical Research Co., Ltd.
Guangdong Provincial People's Hospital

Unknown

Clinical Trial of the Efficacy and Safety of AC0010 in the Treatment of EGFR T790M Patients With Advanded NSCLC

Metastatic Non-small Cell Lung Cancer

China
Second Affiliated Hospital of Soochow University
Qilu Pharmaceutical Co., Ltd.

Unknown

Idebenone Treatment of Early Parkinson's Diseasesymptoms (ITEP)

Oxidative Stress is an Important Cause of Parkinson's Disease
First Affiliated Hospital of Zhejiang University
Ascletis Pharmaceutical Co., Ltd.

Completed

Bioequivalence Study (Preliminary Study) of Ritonavir Versus NORVIR in Healthy Chinese Subjects

Healthy Volunteer

China
Guizhou Bailing Group Pharmaceutical Co Ltd
China-Japan Friendship Hospital

Completed

Clinical Trials for the Optimal Dosage of Tang Ning Tongluo Capsule (TNTL)

Accidental Exposure While Preparing Drug for Administration

China
Hyuk moon Kim
Dong-A Pharmaceutical Co., Ltd.

Unknown

Prevention of Neutropenia After Using G-CSF With TAC Chemotherapy

Neutropenia

Korea, Republic of
Nang Kuang Pharmaceutical Co., Ltd.
Buddhist Tzu Chi General Hospital

Completed

A Clinical Study for Assessment of the Efficacy and Safety of Mirtazapine (Smilon) in Depression Patients With Pain

Depression | Pain

Taiwan
Syneos Health
Merck Sharp & Dohme LLC; Sandoz; Teva Pharmaceuticals USA; Aurobindo Pharma Ltd; Zydus...

Terminated

The Ribavirin Pregnancy Registry (RPR)

Hepatitis C | Pregnancy Complications | Birth Defects

United States
GeneScience Pharmaceuticals Co., Ltd.
Afﬁliated Hospital of North Sichuan Medical College

Recruiting

Clinical Study of Multiple Dose Genakumab for Injection in Chinese Healthy Adults

Interstitial Lung Disease

China
Rush University Medical Center
ElMindA Ltd; Takeda Pharmaceuticals North America, Inc.

Completed

The Relationship Among Changes in Brain Network Activation in Adult Outpatients With Major Depressive Disorder

Major Depressive Disorder

United States
Incepta Pharmaceuticals Ltd
Institute for Developing Science and Health Initiatives, Bangladesh

Recruiting

A Efficacy and Safety Study of Ranibizumab 10mg/ml Injection (Incepta) in Patients With Diabetic Macular Edema

Macular Degeneration | Retinal Degeneration | Diabetic Retinopathy | Diabetic Macular Edema | Macular Edema | Retinal Disease

Bangladesh
George Clinical Pty Ltd
University Medical Center Groningen; Ground Zero Pharmaceuticals

Unknown

An Open Label Phase IV Study to Evaluate Dapagliflozin Treatment in Type 2 Diabetes Mellitus Patients With Impaired Renal Function

Diabetes Mellitus, Type 2 | Impaired Renal Function

Canada
Ahn-Gook Pharmaceuticals Co.,Ltd
Korea University Guro Hospital; Dt&Sanomedics

Unknown

Comparing Safety and Efficacy of Amlodipine Verses S Amlodipine in Patients With Essential Hypertension

Essential Hypertension

Korea, Republic of
Sun Yat-sen University
GeneCast Biotechnology Co., Ltd.; Allist Pharmaceuticals, Inc.

Recruiting

Furmonertinib Monotherapy and Combination Therapy in Advanced EGFR Mutant NSCLC With Uncleared ctDNA (FOCUS-C)

Non-small Cell Lung Cancer

China
Betta Pharmaceuticals Co., Ltd.
The First Affiliated Hospital of Xiamen University

Recruiting

Befotertinib and Icotinib in Treatment-naive Patients With Advanced EGFR-Mutant Lung Cancer

Non-Small Cell Lung Cancer

China
Community and Patient Preference Research Pty Ltd
Seqirus; Glenmark Pharmaceuticals S.A.

Completed

Patient Satisfaction and Sensory Attributes Allergic Rhinitis Nasal Spray

Allergic Rhinitis

Australia
Community and Patient Preference Research Pty Ltd
Seqirus Limited; Glenmark Pharmaceuticals

Withdrawn

Impact of RYALTRIS® Nasal Spray on Patients' Reported Outcomes

Allergic Rhinitis

Australia
AIM Vaccine Co., Ltd.
First Affiliated Hospital Bengbu Medical College; Ningbo Rongan Biological...

Active, not recruiting

A Preliminary Exploratory Cohort Study of COVID-19 mRNA Vaccine, Bivalent in Participants Aged 18 Years and Over in China

SARS-CoV-2

China
Chonbuk National University Hospital
AstraZeneca; Sanofi-Synthelabo; Janssen Korea, Ltd., Korea; Korea Otsuka Pharmaceutical...

Completed

Different Safety Profile of Risperidone and Paliperidone Extended-release

Schizophrenia

Korea, Republic of
U.S. Army Medical Research and Development Command
PPD; Idorsia Pharmaceuticals Ltd.; Berry Consultants; Cambridge Cognition Ltd; Ci...

Not yet recruiting

Department of Defense PTSD Adaptive Platform Trial - Intervention B - Vilazodone

Post Traumatic Stress Disorder
U.S. Army Medical Research and Development Command
PPD; Idorsia Pharmaceuticals Ltd.; Berry Consultants; Cambridge Cognition Ltd; Ci...

Recruiting

Department of Defense PTSD Adaptive Platform Trial Intervention A - Fluoxetine

Post Traumatic Stress Disorder

United States
U.S. Army Medical Research and Development Command
PPD; Idorsia Pharmaceuticals Ltd.; Berry Consultants; Cambridge Cognition Ltd; Ci...

Recruiting

Department of Defense PTSD Adaptive Platform Trial - Master Protocol

Post Traumatic Stress Disorder

United States
AIM Vaccine Co., Ltd.
First Affiliated Hospital Bengbu Medical College; Ningbo Rongan Biological...

Recruiting

Clinical Trial of COVID-19 Vaccine（SARS-CoV-2 Variant(Omicron BA.5) mRNA Vaccine） in Participants Aged 18 Years and Over

SARS-CoV-2

China
The First Affiliated Hospital of Zhengzhou University
BeiGene; Jiangsu Hengrui Pharmaceutical Co., Ltd.; RemeGen Co., Ltd.

Not yet recruiting

Study of Tislelizumab Combined With DisitamabVedotin and Pyrotinib Maleate in HER2-positive or Mutated Advanced Colorectal Cancer Who Failed Standard Therapy

HER2-positive or Mutated Advanced Colorectal Cancer

Clinical Trials Sponsored by Affinium Pharmaceuticals, Ltd

Sponsors and Collaborators

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CROs in Croatia

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