Search clinical trials for: randomized, double-blind, placebo-controlled trial

Total 41454 results

Novartis

Completed

Investigation Into Delay to Diagnosis of Alzheimer's Disease With Exelon (InDDEx)

Alzheimer Disease | Cognition Disorders

United States
Glaxo Wellcome

Completed

A Phase I Study to Evaluate the Pharmacokinetics, Safety and Antiviral Effects of Concurrent Administration of Zidovudine (AZT) and 2'3'-Dideoxyinosine (ddI) in Patients With Human Immunodeficiency Virus (HIV)

HIV Infections

United States
Advanced Peptides

Completed

Intranasal Peptide T in the Treatment of Painful Peripheral Neuropathy of AIDS

HIV Infections | Peripheral Nervous System Disease

United States
Free Radical Sciences

Completed

A Double-Blind, Randomized Parallel Group Study Comparing Procysteine to Placebo in HIV-Infected Patients Who Are Taking Antiretroviral Nucleosides

HIV Infections
Sequus Pharmaceuticals

Unknown

A Comparison of DOX-SL Versus Adriamycin Plus Bleomycin Plus Vincristine in the Treatment of Severe AIDS-Related Kaposi's Sarcoma

HIV Infections | Sarcoma, Kaposi

United States
National Center for Research Resources (NCRR)
University of Vermont

Completed

Phase III Multicenter Double Blind Controlled Trial of Human Immune Globulin Therapy in Previously Untreated Patients With Chronic Inflammatory Demyelinating Neuropathy

Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
Dupont Merck

Completed

A Study of Efavirenz in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs

HIV Infections

United States
GlaxoSmithKline

Unknown

Comparison of Two Dosing Regimens of GW433908/Ritonavir Versus Lopinavir/Ritonavir for 48 Weeks in HIV Patients Who Have Taken Protease Inhibitors and Experienced Virological Failure

HIV Infections

United States
R W Johnson Pharmaceutical Research Institute

Completed

Treatment Program for Anemia in AIDS Patients

HIV Infections | Cytopenias

United States
Hoffmann-La Roche

Completed

A Study of the Safety and Tolerance of Long-Term Therapy With Intravenous Cytovene (Ganciclovir Sodium) for Cytomegalovirus Retinitis in Persons With AIDS

HIV Infections | Cytomegalovirus Retinitis

United States, Canada
Glaxo Wellcome

Completed

A Prospective Double-Blind Study of Retrovir in Early HIV Infection

HIV Infections

United States
Fisons

Completed

A Double-Blind Study To Evaluate the Long-Term Safety and Effectiveness of 60 mg Versus 120 mg of Aerosol Pentamidine in the Prophylaxis of Pneumocystis Carinii Pneumonia in AIDS Patients

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
Glaxo Wellcome

Completed

A Randomized Trial to Evaluate the Safety and Efficacy of Combination Therapy With Retrovir ( AZT ) and HIVID ( ddC ) Versus Retrovir, HIVID, and Wellferon ( Interferon Alfa-n1 ) for the Treatment of HIV Infection

HIV Infections

United States
Merck Sharp & Dohme LLC

Completed

A Six-Month Safety and Antiviral Study in HIV-1 Seropositive, AZT-Experienced Patients With CD4 Counts Less Than or Equal to 50 Cells/mm3 to Evaluate MK-639 Alone Versus Zidovudine (AZT) and 3TC Versus the Combination of MK-639 With AZT/3TC

HIV Infections

United States
Boehringer Ingelheim

Completed

An Open-Label, Non-Randomized Trial to Evaluate the Tolerability and Safety of Viramune (Nevirapine) in Adult and Pediatric Patients With Progressive HIV Disease

HIV Infections

United States
Louisiana State University Health Sciences Center...

Completed

Further Evaluation of Thalidomide's Ability to Potentiate the Immune Response to HIV-Infected Patients

HIV Infections

United States
Ionis Pharmaceuticals, Inc.

Completed

A Study of ISIS 2922 in the Treatment of Advanced Cytomegalovirus Retinitis

HIV Infections | Cytomegalovirus Retinitis

United States
Glaxo Wellcome

Completed

A Study of Retrovir and Epivir Alone or in Combination With 141W94 in HIV-Infected Patients

HIV Infections

United States
Glaxo Wellcome

Completed

A Comparison of 141W94 and Indinavir in HIV-Infected Patients

HIV Infections

United States
Bayer

Completed

Phase III Randomized Double-Blind Placebo Controlled Study To Evaluate the Safety and Efficacy of Betaseron in AIDS and Advanced ARC Patients Receiving a Reduced-Dose AZT Regimen

HIV Infections

United States
Glaxo Wellcome

Completed

A Study of the Effects of Amprenavir, a Protease Inhibitor, on Carbohydrate and Fat Metabolism in HIV-Infected Patients

HIV Infections

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

An Open Parallel Study to Determine the Optimum Dosing Schedule for AS-101 in AIDS/ARC Patients

HIV Infections

United States
Glaxo Wellcome

Completed

A Comparison of 882C87 Versus Acyclovir in the Treatment of Herpes Zoster in Patients With Weakened Immune Systems

HIV Infections | Chickenpox

United States
Gilead Sciences
Anderson Clinical Research

Unknown

A Study of Cidofovir in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS

HIV Infections | Cytomegalovirus Retinitis
Anderson Clinical Research
Boehringer Mannheim

Completed

The Safety and Effectiveness of Fozivudine Tidoxil in HIV-1 Infected Patients

HIV Infections
Glaxo Wellcome

Completed

A Study of the Safety and Effectiveness of Different Doses of 1592U89 in HIV-Infected Patients

HIV Infections

France, Germany
U.S. Bioscience

Completed

A Study of Neutrexin Plus Leucovorin in the Treatment of Pneumocystis Carinii Pneumonia (PCP)

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
Gilead Sciences

Unknown

The Safety of Tenofovir Disoproxil Fumarate Taken With Other Anti-HIV Drugs to Treat HIV-Infected Patients

HIV Infections

United States
Triangle Pharmaceuticals

Unknown

Emtricitabine Given Once A Day With Other Anti-HIV Drugs in Children With HIV

HIV Infections

United States, Argentina, Mexico, Panama, Puerto Rico, South Africa
Roche Global Development

Completed

An Open Label Evaluation of the Safety and Pharmacokinetics of Ganciclovir in Children

HIV Infections | Cytomegalovirus Retinitis

United States
University of California, San Francisco

Completed

A Randomized Controlled Prophylactic Study of Clofazimine To Prevent Mycobacterium Avium Complex Infection in HIV Disease

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States
Pfizer

Completed

An Open, Non-Comparative Study of Intravenous and Oral Fluconazole in the Treatment of Acute Cryptococcal Meningitis

HIV Infections | Meningitis, Cryptococcal

United States
Otsuka America Pharmaceutical

Completed

A Phase I Study of Three Doses of OPC-8212 (Vesnarinone) in HIV-Infected Persons With CD4+ Cell Number > 300 Cells/mm3

HIV Infections

United States
Hoffmann-La Roche

Completed

A Randomized, Parallel Arm, Comparative, Open Label, Multicenter Study of the Activity and Safety of Two Formulations of Saquinavir in Combination With Other Antiretroviral Drugs

HIV Infections

Canada, United States
Gilead Sciences

Unknown

Safety and Effectiveness of Adding Adefovir Dipivoxil and Nelfinavir to the Anti-HIV Therapy of HIV-Infected Children

HIV Infections

United States
Sandoz

Completed

A Randomized, Phase I/II Trial to Assess the Safety and Antiviral Effects of Escalating Doses of A Human Anti-Cytomegalovirus Monoclonal Antibody (SDZ MSL-109) in Patients With the Acquired Immunodeficiency Syndrome and CMV Viremia and/or Viruria

HIV Infections | Cytomegalovirus Infections

United States
Hoffmann-La Roche

Completed

A Study of Ganciclovir in the Treatment of Cytomegalovirus of the Large Intestine in Patients With AIDS

HIV Infections | Colitis

United States
Astra USA

Unknown

A Study of Foscarnet in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS Who Have Not Had Success With Ganciclovir

HIV Infections | Cytomegalovirus Retinitis

United States
Ortho Pharmaceuticals

Completed

The Safety and Effectiveness of r-HuEPO in Patients With AIDS and Anemia Caused by AIDS and Treatment With AZT

HIV Infections | Cytopenias

United States
Boehringer Ingelheim

Completed

The Safety and Effectiveness of Nevirapine and Zidovudine, Given Separately and Together, in HIV-1 Infected Patients Who Have No Symptoms of the Disease

HIV Infections

United States
Rockefeller University

Completed

A Study of Thalidomide in HIV-Infected Patients Who Are Receiving HAART

HIV Infections

United States
Pharmacia and Upjohn

Completed

A Study of Two Anti-HIV Drug Combinations in HIV-Infected Patients

HIV Infections

United States
Gilead Sciences

Completed

Safety and Effectiveness of Tenofovir Disoproxil Fumarate (Tenofovir DF) Plus Other Anti-HIV Drugs in HIV-Infected Patients

HIV Infections

United States, Puerto Rico
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Trial of Smoking Cessation Programs in Black Churches

Heart Diseases | Cardiovascular Diseases | Coronary Heart Disease Risk Reduction
Celgene Corporation

Completed

Study to Compare the Efficacy and Safety of Two CC-5013 Dose Regimens in Subjects With Metastatic Malignant Melanoma

Melanoma | Neoplasm Metastasis

United States, Canada
Royal Brompton & Harefield NHS Foundation Trust
CORDA, The Heart Charity; Apotex Inc.; The Cooley's Anemia Foundation,; The UK...

Unknown

Combined Chelation Treatment With Deferiprone and Deferoxamine in Thalassemia Major

Beta-Thalassemia

Italy
Amgen

Completed

Evaluation of the Therapeutic Benefit of r-metHuIFN- Gamma in AIDS Patients With Disseminated Mycobacterium Avium-Intracellulare (MAI) Infection: A Multi-Centered Pilot Study

HIV Infections | Mycobacterium Avium-Intracellulare Infection

United States
Merck Sharp & Dohme LLC

Completed

A Multicenter, Open-Label, Randomized, 24-Week Study to Compare the Safety and Activity of Indinavir Sulfate, 800 Mg q 8 h Versus 1,200 Mg q 12 h in Combination With Zidovudine and 3TC

HIV Infections

United States
Triangle Pharmaceuticals

Unknown

A Comparison of Emtricitabine and Stavudine Used With Didanosine Plus Efavirenz in HIV-Infected Patients Who Have Not Taken Anti-HIV Drugs

HIV Infections

United States, Puerto Rico, Canada, Argentina, Chile, Mexico
Sandoz

Completed

An Open Label Phase I Study of Subcutaneously Administered Recombinant Human GM-CSF in Patients With AIDS Virus Infection and Leukopenia

HIV Infections | Cytopenias

United States

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