Search clinical trials for: Proof of Concept

Total 432461 results

Finnish Institute for Health and Welfare

Completed

Comparative Trial Of Disulfiram, Naltrexone And Acamprosate In The Treatment Of Alcohol Dependence (DNA)

Alcohol Dependence

Finland
Kansai Medical University

Completed

Characterization of Macroprolactinemia

Hyperprolactinemia

Japan
Azienda Ospedaliera San Giovanni Battista
Hoffmann-La Roche; University of Turin, Italy; Gruppo Italiano Trapianto di Midollo... and other collaborators

Unknown

Comparison of High-Dose Chemotherapy + Rituximab and CHOP + Rituximab in High-Risk Follicular Lymphoma

Follicular Lymphoma

Italy
C.R.Darnall Army Medical Center

Completed

Ease-it Spray for the Treatment of Fire Ant Stings

Insect Bites and Stings
IDRI
Bill and Melinda Gates Foundation

Completed

Study to Evaluate the Leish-111F + MPL-SE Vaccine in the Treatment of Mucosal Leishmaniasis

Leishmaniasis, Mucocutaneous

Peru
IDRI
Bill and Melinda Gates Foundation

Completed

Study to Evaluate the Leish-111F + MPL-SE Vaccine in the Treatment of Cutaneous Leishmaniasis

Leishmaniasis, Cutaneous

Brazil
Johns Hopkins Bloomberg School of Public Health
Walter Reed Army Institute of Research (WRAIR); Naval Medical Research Center

Completed

Efficacy of Anti-CFA/I and CfaE Bovine Milk Immunoglobulin Against Challenge With H10407 ETEC Expressing CFA/I (BIgGI)

Diarrhea

United States
University of Oslo

Completed

A Randomized Clinical Trial on Supplementation of DHA and AA to Preterm Infants

Infant, Low Birth Weight

Norway
Millennium Pharmaceuticals, Inc.

No longer available

A Study to Assess Two Different Strategies of Combining Dexamethasone and VELCADE

Multiple Myeloma

United States
University of Massachusetts, Worcester

Completed

Provider and Peer Delivered Youth Smoking Intervention

Tobacco Dependence

United States
Hadassah Medical Organization

Unknown

Computer Assisted Early Detection of Liver Metastases From fMRI Maps

Metastatic Colorectal Cancer

Israel
University Health Network, Toronto
Canadian Institutes of Health Research (CIHR); The Arthritis Society, Canada

Unknown

HIPP Learning to Live Better With Lupus: The Health Improvement and Prevention Program in Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

Canada
University of British Columbia
Eli Lilly and Company

Completed

Dietary Intake and Nutrient Status of Children With ADHD

Attention Deficit Hyperactivity Disorder

Canada
Rigshospitalet, Denmark
Novo Nordisk A/S; University of Copenhagen; AP Moeller Foundation

Completed

Hypopituitarism Following Traumatic Brain Injury or Spontaneous Subarachnoidal Haemorrhages

Brain Injuries | Intracranial Aneurysm

Denmark
University of Aarhus

Completed

Acute Metabolic Effects of Estradiol

Postmenopause

Denmark
Mario Negri Institute for Pharmacological Research

Completed

Ezetimibe and Simvastatin in Dyslipidemia of Diabetes

Type 2 Diabetes

Italy
University Hospital, Angers

Unknown

Impact of nCPAP Treatment on Liver Function in Patients With Sleep Apnea Syndrome and Nonalcoholic Steatohepatitis

Nonalcoholic Steatohepatitis | Sleep Apnea Syndrome

France
Georgia Center for Oncology Research & Education
Sanofi

Unknown

Docetaxel Followed by Capecitabine Versus Concomitant Docetaxel/Capecitabine for Early Stage Breast Cancer

Breast Neoplasms

United States
Pfizer

Completed

Six Month Clinical Trial Assessing Efficacy And Safety Of Inhaled Insulin In Type 1 Diabetes Mellitus.

Diabetes Mellitus, Type 1

United States, Canada
Cubist Pharmaceuticals LLC

Terminated

HepeX-B in Post Hepatic Allografts for Treatment of End Stage Liver Disease Due to Hepatitis B Infection

Liver Transplantation | Hepatitis B

New Zealand, United States, Israel, United Kingdom, France, Germany, Spain
Pfizer
Sanofi; Nektar Therapeutics

Completed

Effect on Glycemic Control of Inhaled Insulin Alone or Added to Dual Oral Therapy After Failure of Dual Oral Therapy.

Diabetes Mellitus, Type 2

United States, Canada
Pfizer

Completed

Six Month Clinical Trial Assessing Efficacy And Safety Of Inhaled Insulin In Type 2 Diabetes

Diabetes Mellitus, Type 2

United States, Canada
Innovative Medical

Completed

Efficacy of Topical Cyclosporine 0.05% in the Prevention of Ocular Surface Inflammation Secondary to Pterygia

Pterygia

United States
Aravind Medical Research Foundation

Unknown

Outcome of Small Pupil Phacotrabeculectomy in Persons With Glaucoma and Cataract

Glaucoma | Cataract
Laserklinik Karlsruhe

Completed

Comparative Study of the Effect of Dysport and Botox

Aging

Germany
Pfizer

Completed

Six Month Clinical Trial Assessing Efficacy and Safety of Inhaled Insulin in Type 1 Diabetes

Diabetes Mellitus, Type 1

United States, Canada
Eli Lilly and Company

Completed

Comparison of LY686017 With a Marketed Drug in the Treatment of Social Anxiety Disorder

Social Phobia

United States
Menzies School of Health Research
World Health Organization; Universidade da Paz

Completed

Food Incentives for TB Treatment Compliance in East Timor (FITTCET)

Tuberculosis

Australia
Medical University of Vienna

Completed

Effects of Topical Clonidine vs. Brimonidine on Choroidal Blood Flow and Intraocular Pressure During Isometric Exercise

Ocular Physiology | Regional Blood Flow

Austria
Medical University of Vienna

Completed

Effects of Indomethacin on Retinal and Choroidal Blood Flow in Healthy Volunteers

Ocular Physiology | Regional Blood Flow

Austria
Women and Infants Hospital of Rhode Island

Terminated

Essiac (ESIAK) Versus Placebo to Improve Quality of Life in Transition in Women With Breast or Ovarian Cancer.

Breast Cancer | Ovarian Cancer

United States
POZEN

Completed

To Evaluate the Safety and Efficacy of Trexima in the Acute Treatment of Migraine Headaches

Migraine Headaches

United States
University of Melbourne
Clinical Vision Research Australia; Cooper Companies

Completed

Investigation of the Clinical Performance of Silicone Hydrogel Contact Lenses During Continuous Wear

Myopia

Australia
Abant Izzet Baysal University

Unknown

A Study Evaluating the Effects of Lipid Lowering Treatment on Steroid Synthesis

Diabetes Mellitus | Hypercholesterolemia | Coronary Heart Disease | Non-Coronary Atherosclerotic Disease

Turkey
POZEN

Completed

To Evaluate the Safety and Efficacy of Trexima in the Acute Treatment of Migrane Headaches

Migraine Headaches

United States
University of Calgary
Canadian Institutes of Health Research (CIHR); LEO Pharma; Dupont Applied Biosciences

Completed

Trial of the Effect of Low-Molecular-Weight Heparin (LMWH) Versus Warfarin on Mortality in the Long-Term Treatment of Proximal Deep Vein Thrombosis (DVT) (Main LITE Study)

Thrombosis | Venous Thrombosis | Thromboembolism

Canada
AstraZeneca

Completed

SAKK - a Trial to Evaluate Antitumor Efficacy of Faslodex® After Aromatase Inhibitor Failure in Advanced Breast Cancer

Breast Neoplasms

Belgium, Switzerland
Free Islamic University of Medical Sciences

Completed

Metabolic Syndrome and Inflammatory Markers

Metabolic Syndrome
Aga Khan University

Completed

Efficacy of L-Ornithine-L-Aspartate in Cirrhotics With Hepatic Encephalopathy

Hepatic Encephalopathy

Pakistan
University of Calgary
Canadian Institutes of Health Research (CIHR); LEO Pharma; Dupont Applied Biosciences

Completed

Assessment of Long-Term Out-of-Hospital Treatment of Patients With Proximal Deep Vein Thrombosis (DVT) Using Low-Molecular-Weight Heparin (LMWH) Versus LMWH Followed by Warfarin

Thrombosis | Venous Thrombosis | Thromboembolism

Canada
Semmelweis University

Unknown

Autoimmunity in Retinitis Pigmentosa

Retinitis Pigmentosa

Hungary
Innovative Medical

Completed

Bimatoprost Monotherapy vs. Dual Therapy With Travoprost and Timolol in Patients With Glaucoma and Ocular Hypertension

Glaucoma

United States
The New England Center for Headache, P.C.
Ortho-McNeil Neurologics, Inc.

Unknown

Detoxification and Treatment of Subjects With Medication Overuse Headache

Analgesic Rebound Headache

United States
Hospital do Cancer, Sao Paulo

Completed

Saline Instillation Before Tracheal Suctioning and the Incidence of Ventilator Associated Pneumonia

Critically Ill Patients | Mechanical Ventilation

Brazil
Charite University, Berlin, Germany
Hoffmann-La Roche

Unknown

Open Label Clinical Trial With Rituximab (MabThera ®) in Ankylosing Spondylitis

Ankylosing Spondylitis

Germany
National Center for Complementary and Integrative...

Completed

Herb-Opioid Interactions

Pain

United States
Abbott

Completed

The Safety and Efficacy of Divalproex Sodium Extended-Release Tablets in Migraine Prophylaxis: A Study in Adolescents

Migraine

United States
Sarepta Therapeutics, Inc.
Baim Institute for Clinical Research

Completed

Safety and Efficacy of RESTEN-MP When Used in Conjunction With a Bare Metal Stent in Coronary Arteries

Coronary Artery Disease | Coronary Restenosis

Germany
Hospital Clinic of Barcelona

Completed

The Use of Cervical Length to Reduce Hospital Stay in Women Admitted Because of Preterm Labor.

Cervical Length | Labor, Premature

Spain
Assistance Publique - Hôpitaux de Paris

Terminated

Influenza Vaccination of Nursing Home Workers.

Influenza Disease

France

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