Search clinical trials for: KRAS mutation

Total 4483 results

Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Withdrawn

Biomarkers in Stored Tumor Samples From Younger Patients With Liver Cancer

Liver Cancer
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Completed

DNA Analysis of Tissue Samples From Patients With Head and Neck Cancer

Head and Neck Cancer
WiSP Wissenschaftlicher Service Pharma GmbH
Gesellschaft fur Medizinische Innovation - Hamatologie und Onkologie mbH

Suspended

Panitumumab Plus Pemetrexed and Cisplatin (PemCisP) Versus PemCis in the First-line Treatment of Patients With Non-small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung

Germany
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Terminated

Studying Common Genetic Mutations Related to Mucositis in Patients With Multiple Myeloma Receiving High-Dose Melphalan

Mucositis | Multiple Myeloma and Plasma Cell Neoplasm

United States
University of Roma La Sapienza

Unknown

Ranolazine for Improving Symptoms of Palpitations (RYPPLE)

Ischemic Heart Disease
AIO-Studien-gGmbH
iOMEDICO AG

Terminated

Study to Evaluate the Effects of Panitumumab if Combined With Chemotherapy for 2nd Treatment of Colorectal Cancer (VOXEL)

Colorectal Neoplasms

Germany
University Health Network, Toronto

Completed

Postoperative Melatonin Administration and Delirium Prevention in Patients Undergoing Vascular and Cardiac Surgery

Cardiac Surgery

Canada
Vertex Pharmaceuticals Incorporated
Cystic Fibrosis Foundation

Completed

Study of the Effect of Ivacaftor on Lung Clearance Index in Subjects With Cystic Fibrosis and the G551D Mutation

Cystic Fibrosis

United Kingdom, United States, Canada
Università Vita-Salute San Raffaele
IRCCS San Raffaele; Merck Sharp & Dohme LLC

Unknown

GePheRal: Clinical Validation of the Genotypic Diagnosis of Hiv-1 Resistance to Raltegravir by Parallel Analysis of the Genotype and Phenotype Profiles of Resistance

HIV-1 Infected Patients | Fold-change Resistance | Resistance Mutations

Italy
Cukurova University

Completed

MEVALONATE KINASE GENE MUTATIONS AND THEIR CLINICAL CORRELATIONS IN BEHÇET'S DISEASE

Behçet's Disease

Turkey
Samsung Medical Center
AstraZeneca

Unknown

Evaluation of EGFR TKI Resistance Mechanism Using Plasma DNA Analysis

EGFR Mutation Positive Non-small Cell Lung Cancer

Korea, Republic of
Sanofi

Completed

Evaluation of AVE5026 in the Prevention of Venous Thromboembolism in Cancer Patients Undergoing Chemotherapy (SAVE-ONCO)

Cancer | Venous Thromboembolism

France, Spain, Hong Kong, Austria, Canada, Lithuania, South Africa, Sweden, Romania, United States, Greece, Korea, Republic of, Ukraine, Argentina, Australia, Belarus, Belgium, Brazil, Bulgaria, Chile, China, Colombia, Croatia, Czech... and more
Catholic University of the Sacred Heart

Unknown

Study With Trabectedin in BRCA1 and BRCA2 Mutation Carrier and BRCAness Phenotype Ovarian Cancer (MITO15)

BRCA1 and BRCA2 Mutation Carrier and BRCAness Phenotype

Italy
AbbVie (prior sponsor, Abbott)

Completed

Kaletra: Therapy With Double Protease Inhibitors

Human Immunodeficiency Virus

Germany
Vertex Pharmaceuticals Incorporated
Cystic Fibrosis Foundation

Completed

Study of Ivacaftor in Cystic Fibrosis Subjects Aged 12 Years and Older With the G551D Mutation (STRIVE)

Cystic Fibrosis

United States, Canada, Australia, Ireland, France, United Kingdom, Germany, Czech Republic
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

T-cell Childhood Acute Lymphoblastic Leukemia | Untreated Childhood Acute Lymphoblastic Leukemia

United States
National Cancer Institute (NCI)

Completed

Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Children With Acute Myelogenous Leukemia or Myelodysplastic Syndrome

Chronic Myelomonocytic Leukemia | Childhood Acute Erythroleukemia (M6) | Childhood Acute Megakaryocytic Leukemia (M7) | Childhood Acute Monoblastic Leukemia (M5a) | Childhood Acute Monocytic Leukemia (M5b) | Childhood Acute Myeloblastic Leukemia With Maturation (M2) | Childhood Acute Myeloblastic... and other conditions

United States
AstraZeneca

Completed

Study of Selumetinib (AZD6244)(ARRY-142886) in Combination With Irinotecan in Previously Treated Patients With Colorec

Colorectal Cancer

United States
Dr.Laurent Mineur
Merck Serono International SA; BESPIM, CHU Nîmes (data analysis)

Unknown

PREMIUM, Observational Study

First Line WT KRAS mCRC

France
H. Lundbeck A/S

Completed

Short-term Study of Combination Treatment of Escitalopram and Gaboxadol in Major Depressive Disorder

Major Depressive Disorder

Austria, Russian Federation
Peking Union Medical College Hospital

Unknown

Vinorelbine-ifosfamide Versus Gefitinib for EGFR Gene Mutation Negative Non-small Cell Lung Cancer Patients

Non-small Cell Lung Cancer | Effects of Chemotherapy

China
Nantes University Hospital

Terminated

Analysis of Oculo-motor Deficiencies Associated With FMR1 Gene Expression (Genetic Abnormality Predisposing to a Neurodegenerative Disease)

Pre-mutation on FMR1 Gene

France
Chinese Society of Lung Cancer

Completed

Study of Pemetrexed Versus Gefitinib in Patients With Locally Advanced or Metastatic Non Small Cell Lung Cancer Who Have Previously Received Platinum-Based Chemotherapy Without Epidermal Growth Factor Receptor (EGFR) Mutations

Non Small Cell Lung Cancer

China
Abbott
Almedis; Scientific Research Institute of Rheumatology, Moscow

Completed

Study to Characterize Demographics, Compliance, Tolerability and Safety in Patients With Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis Prescribed Adalimumab (Humira®) as Part of Routine Clinical Care

Rheumatoid Arthritis | Psoriatic Arthritis | Ankylosing Spondylitis

Russian Federation
M.D. Anderson Cancer Center

Terminated

Melatonin Postoperative Sleep Study in Breast Cancer Patients

Breast Cancer

United States
GlaxoSmithKline

Completed

Second-Line Therapy Study For Potentially Platinum-Sensitive Relapsed Ovarian Cancer

Ovarian Cancer | Neoplasms, Ovarian

United States, Canada
Assistance Publique - Hôpitaux de Paris

Terminated

Trial of High Dose Topotecan With Carboplatin in Patients With Relapsed Ovarian Carcinoma (ITOV04)

Ovarian Cancer | Relapses

France
Assistance Publique - Hôpitaux de Paris

Completed

Efficacy and Safety Study of Sulfonylureas in Neonatal Diabetes Mellitus (GLIDKIR6-2)

Diabetes Mellitus

France
National Taiwan University Hospital

Unknown

PHOX2B Mutation-Confirmed Congenital Central Hypoventilation Syndrome in A Chinese Family: Presentations From Newborn to Adulthood

Central Alveolar Hypoventilation Syndrome

Taiwan
Grupo Gallego de Cancer de Pulmon
AstraZeneca; Dynamic Solutions

Unknown

Observational Study to Characterize the Incidence of EGFR Mutation Positive and Advanced NSCLC Patients

Metastatic Non-Small-Cell Lung Cancer

Spain
AstraZeneca

Completed

A Study to Observe Real-life Allocation of Antipsychotics in Acute Inpatient Management of Schizophrenia (RECONNECT-S)

Schizophrenia

Russian Federation
Anthera Pharmaceuticals

Terminated

VISTA-16 Trial: Evaluation of Safety and Efficacy of Short-term A-002 Treatment in Subjects With Acute Coronary Syndrome (VISTA-16)

Acute Coronary Syndrome

United States, Australia, Canada, Czech Republic, Georgia, Germany, Hungary, India, Italy, Korea, Republic of, Lebanon, Netherlands, New Zealand, Poland, Russian Federation, Spain, Ukraine
Vejle Hospital

Completed

Panitumumab and Pegylated Liposomal Doxorubicin for Platinum-Resistant Epithelial Ovarian Cancer With KRAS Wild-type (PaLiDo)

Epithelial Ovarian Cancer

Denmark, Belgium, Sweden, Austria
Spanish Lung Cancer Group
Merck Sharp & Dohme LLC

Terminated

Phase I/II of Oral Vorinostat Combination With Erlotinib in NSCLC Patients With EGFR Mutations With DP After Erlotinib.

Non-small Cell Lung Cancer

Spain
Korea University
GlaxoSmithKline

Completed

Adding Adefovir Dipivoxil Versus Switching to Entecavir in Patients With Lamivudine-resistant Chronic Hepatitis B

Chronic Hepatitis B

Korea, Republic of
Vertex Pharmaceuticals Incorporated
Cystic Fibrosis Foundation

Completed

Safety Study of Ivacaftor in Subjects With Cystic Fibrosis

Cystic Fibrosis

United States, Canada, Germany
Severance Hospital
AstraZeneca

Unknown

De Novo Resistance to Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors

NSCLC
AstraZeneca

Completed

SELINE: Second-Line Iressa Phase IV Study in NSCLC Patients (SELINE)

Non Small Cell Lung Carcinoma

Korea, Republic of
Institut National de la Santé Et de la Recherche...

Unknown

Clinical, Molecular and by Neuroimaging of LRRK2 Mutations (LRRK2)

Parkinson's Disease

France
Helsinki University Central Hospital

Unknown

Clinical Importance of Filaggrin Gene Mutation for Treatment Outcome in Atopic Dermatitis

Atopic Dermatitis

Finland
Memorial Sloan Kettering Cancer Center
Memorial Health University Medical Center

Completed

BRCA1 Haploinsufficiency and Gene Expression

BRCA1 Mutations

United States
AstraZeneca

Completed

Observational Study on the Management of Patients With Non Small Cell Lung Cancer Adenocarcinoma (MUTACT)

Non Small Cell Lung Cancer

France
Agenus Inc.

Completed

Study of Heat Shock Protein-Peptide Complex (HSPPC-96) Versus IL-2/DTIC for Stage IV Melanoma

Malignant Melanoma

United States, Australia, Poland, Ukraine, United Kingdom, Russian Federation, Hungary, Italy, Sweden
Cephalon

Completed

Open Study of CEP-701 in Patients With Refractory Acute Myeloid Leukemia With FLT-3 Mutation

Leukemia, Myeloid
Agennix

Completed

Safety and Efficacy of Talactoferrin in Previously Treated Patients With Non-small Cell Lung Cancer (FORTIS-M)

Non Small Cell Lung Cancer

United States, Spain, France, Canada, Bulgaria, Australia, Russian Federation, Turkey, Taiwan, Hungary, Philippines, Czech Republic, Germany, Greece, India, Italy, Korea, Republic of, Latvia, Malaysia, Poland, Romania, Singapore, United...
Vertex Pharmaceuticals Incorporated
Cystic Fibrosis Foundation

Completed

Study of Ivacaftor in Cystic Fibrosis Subjects Aged 6 to 11 Years With the G551D Mutation (ENVISION)

Cystic Fibrosis

United States, Australia, Canada, France, Germany, Ireland, United Kingdom
Dana-Farber Cancer Institute

Withdrawn

Olaparib for Patients With Recurrent BRCA Deficient Ovarian Cancer

Ovarian Cancer | Fallopian Tube Cancer | Peritoneal Cancer

United States
Assistance Publique - Hôpitaux de Paris

Completed

Immunological Consequences of CARD15/NOD2 Mutations in Crohn's Disease (PLAC)

Crohn's Disease

France
Victor J Marder, M.D.
Baxter Healthcare Corporation

Unknown

Personalized Prediction of Tolerance and Immunogenicity in Hemophilia (PPTIH)

Hemophilia A

United States
Adherex Technologies, Inc.

Unknown

Study of Eniluracil + 5-Fluorouracil (5-FU) + Leucovorin Versus Capecitabine in Metastatic Breast Cancer

Metastatic Breast Cancer

United States, Russian Federation

Search clinical trials for: KRAS mutation

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