Search clinical trials for: Dexmedetomidine supplemented morphine analgesia

Total 3801 results

Abdelrady S Ibrahim, MD

Completed

The Effect of Adding Nalbuphine to Intrathecal Morphine on Analgesic Efficacy and Side Effects After Cesarean Section

Postoperative Pain

Egypt
Centre Hospitalier Universitaire Vaudois

Completed

Femoral Neuropathy After Anterior Cruciate Ligament Reconstruction: Femoral Nerve Block vs Patient-controlled Analgesia (PCA)

Femoral Neuropathy

Switzerland
Johnson & Johnson Taiwan Ltd

Terminated

A Study to Compare Safety and Efficacy of Osmotic Release Oral Syytem (OROS) Hydromorphone Hydrochloride (HCl) With Morphine Sustain Release (SR) in Participants With Cancer Pain

Cancer Pain
Member Companies of the Opioid PMR Consortium

Terminated

Discontinuation vs Continuation of Long-term Opioid Therapy in Suboptimal and Optimal Responders With Chronic Pain

Opioid-Related Disorders | Drug Abuse | Opiate Addiction | Narcotic Abuse

United States
The First Affiliated Hospital with Nanjing Medical...

Recruiting

Safety and Efficacy of Esketamine Combined With Dexmedetomidine for Sedation of Mechanically Ventilated Patients (SEEDS)

Analgesia | Ketamine | Dexmedetomidine | Mechanical Ventilation | Intensive Care Units

China
China Medical University Hospital

Unknown

NALDEBAIN for Postoperative Pain Management in Take Down of Anastomosis

Postoperative Pain

Taiwan
Mundipharma (China) Pharmaceutical Co. Ltd

Unknown

A Study to Evaluate Buprenorphine Transdermal Patch in Chinese Subjects With Moderate to Severe Chronic Cancer Pain

Cancer Pain

China
Labtec GmbH

Withdrawn

A Safety and Efficacy Study of Sufentanil Transdermal System in Patients With Chronic Pain Due to Cancer

Chronic Pain
Trevena Inc.

Completed

Pharmacokinetics and Pharmacodynamics of TRV130, Morphine, and Placebo in Healthy Subjects

Pain, Acute

United States
Inonu University

Completed

Efficacy of Intravenous Ibuprofen and Paracetamol on Postoperative Pain and Morphine Consumption in Lumbar Disc Surgery (ibuprofen)

Postoperative Pain Management

Turkey
Beijing Chao Yang Hospital

Recruiting

Effect of Postoperative Prolonged Sedation With Dexmedetomidine After Successful Reperfusion With EVT on Long-term Prognosis in Patients With AIS (PPDET)

Acute Ischemic Stroke

China
Affiliated Hospital of Nantong University

Completed

Effect of Dexmedetomidine Preconditioning on Myocardial Ischemia-reperfusion Injury in Patients Undergoing Open Heart Surgery With Cardiopulmonary Bypass

Ischemia-Reperfusion Injury

China
New York State Psychiatric Institute

Withdrawn

Anti-suicidal Effects of Buprenorphine in Opioid Use Disorder

Suicidal Ideation | Opioid-use Disorder

United States
Mallinckrodt

Completed

Drug Interactions Between Morphine and Orally or IV Administered Acetaminophen

Pain

United States
St. Antonius Hospital
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Completed

Pharmacokinetics of Morphine and Oxycodone in Frail Elderly Undergoing Cardiac Surgery

Postoperative Pain | Opioid Use | Side Effect of Drug

Netherlands
Pacira Pharmaceuticals, Inc
Registrat-Mapi

Terminated

A Health Economic Trial in Adult Patients Undergoing Open Colectomy MA402S23B301 (IMPROVE-Open)

Bowel Obstruction

United States
Pacira Pharmaceuticals, Inc
Registrat-Mapi

Terminated

A Health Economic Trial in Adult Patients Undergoing Open Colectomy MA402S23B302 (IMPROVE-Open)

Bowel Obstruction

United States
Pacira Pharmaceuticals, Inc
Registrat-Mapi

Completed

Adult Patients Undergoing Open Colectomy MA402S23B303 (IMPROVE-Open)

Bowel Obstruction

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Intranasal Sufentanil for Analgesia of Severe Sickle Cell Vaso-occlusive Pain Crisis in the Pediatric (INVOPE)

Vaso-occlusive Crisis
Menoufia University

Completed

Comparative Study on the Effect of Quadratus Lumborum Block Versus Intrathecal Morphine on the Incidence of Chronic Pain Post Caesarean Section in a University Hospital of Middle-income Country

Chronic Post Cesarean Pain

Egypt
Trevena Inc.
Lotus Clinical Research, LLC

Completed

A Study of TRV130 for the Treatment of Pain After Abdominoplasty

Pain

United States
Hopital Lariboisière

Unknown

Sustained-release Morphine Pharmacokinetics in Roux-en-Y Gastric Bypass Subjects (OBEMO2)

Bypass Complications

France
Cork University Hospital

Unknown

The Analgesic Efficacy of Local Anaesthetic Wound Infiltration Versus Intrathecal Morphine for Total Knee Replacement

Total Knee Replacement

Ireland
Actavis Inc.

Completed

Comparison of One Morphine Sulfate Sustained-Release 200mg Capsule With Two 100 mg KADIAN Capsules Under Fed Conditions

Healthy

United States
Yao Yusheng
West China Hospital

Completed

Caudal Versus Intravenous Dexmedetomidine for Supplementation of Caudal Analgesia in Children

Inguinal Hernia | Cryptorchidism

China
Kocaeli University

Completed

Comparison of Erector Spinae Plane Block With Thoracic Paravertebral Block for Breast Surgery

Breast Cancer | Postoperative Pain

Turkey
Erasme University Hospital

Completed

Nol-Index Guided Remifentanil Analgesia Versus Standard Analgesia During Moderate-to-High Risk Cardiovascular Surgery

Cardiac Surgery | General Anesthesia | Hemodynamic Instability | Nociceptive Pain | Goal-directed Therapy | Nol-Index | Remifentanil | Vascular Surgery

Belgium
University of Southern California

Not yet recruiting

Erector Spinae Plane Block for Rib Fracture Analgesia in the Emergency Department

Rib Fracture Multiple
Shanghai Ninth People's Hospital Affiliated to...

Completed

Sedation Effect of Dexmedetomidine Versus Remifentanil to Fibreoptic Intubation

Intubation; Difficult

China
Joseph Cravero

Completed

A Pilot Study of Dexmedetomidine-Propofol in Children Undergoing Magnetic Resonance Imaging

Epilepsy | Cerebral Palsy | Developmental Delay

United States
Nantes University Hospital

Terminated

Analgesic Strategies in Newborns Receiving Prostaglandin Therapy

Pain

France
National Cancer Institute, Egypt

Completed

Erector Spinae Plane Block Versus General Anesthesia in Breast Cancer Surgeries

Analgesia

Egypt
Pacira Pharmaceuticals, Inc

Terminated

Evaluation of the Safety and Efficacy of EXPAREL When Administered Into the TAP in Subjects Undergoing Cesarean Section

Pain

United States
Beth Israel Deaconess Medical Center

Terminated

The Optimal Dosage of Intrathecal Morphine for Peripartum Analgesia

Labor Pain

United States
Cork University Hospital

Unknown

The Analgesic Efficacy of Periarticular Infiltration of Local Anaesthetic for Total Hip Replacement

Total Hip Arthroplasty

Ireland
Pharmaceutical Research Management srl
European Commission

Withdrawn

Efficacy and Safety Study of Gabapentin as add-on to Morphine in Paediatric Patients Affected by Chronic Pain (GABA-2)

Chronic Pain
Assiut University

Completed

Pharmacokinetics and Pharmacodynamics of Oral Transmucosal Dexmedetomidine. (OTM/DEX/PK)

Sedation

Egypt
University of Jordan

Completed

Caudal Versus Intravenous Dexmedetomidine for Caudal Analgesia in Children

Pain
University of Turku

Unknown

A Comparative Study With Parenteral Oxycodone, Morphine and Dexamethasone in Postoperative Pain in Paediatric Patients (DOM)

Post Tonsillectomy Pain

Finland
Nourhan M.Aly
Alexandria University

Completed

Sublingual Versus Intranasal Administration of Dexmedetomidine for Sedation of Children Undergoing Dental Treatment

Moderate Sedation | Anti-anxiety Agents

Egypt
Brigham and Women's Hospital
National Institute on Drug Abuse (NIDA)

Active, not recruiting

Sensory Effects of Oral Opioid Treatment in Patients With Chronic Low Back Pain

Low Back Pain

United States
Goodman, Evan, M.D.

Terminated

Epidural Morphine Versus Epidural Fentanyl Infusion Following Cesarean Section

Pain

United States
Institut National de la Santé Et de la Recherche...

Completed

Double Blind Randomized, Monocentric, Cross-over, Placebo-controlled Study to Evaluate the Effect of Morphine and Naloxone on Motivation (MBBAnalgesic) (MBBAnalgesic)

Healthy

France
Assiut University

Completed

Sequential and Mixture Injection of Opioids and Hyperbaric Bupivacaine

Cesarean Section Complications | Regional Anesthesia Morbidity | Bupivacaine Adverse Reaction

Egypt
Antonios Likourezos
Emergency Medicine Foundation

Completed

Ultrasound Guided Pain Control Versus Standard Treatment in Emergency Department HIP Fracture Patients

Hip Fracture

United States
Pfizer

Terminated

Conversion to Embeda With Rescue Trial (ConvERT)

Pain | Chronic Disease

United States
Ciusss de L'Est de l'Île de Montréal

Withdrawn

Improving ObsQoR-11 With Continuous Wound Infusion Versus Intrathecal Morphine After Elective Cesarean Delivery (CIVIMEC)

Postoperative Pain | Cesarean Section | Anesthesia | Quality of Recovery

Canada
MetroHealth Medical Center

Completed

Lifeflight: Fentanyl Versus Morphine

Adverse Events | Pain Relief

United States
Columbia University

Completed

Efficacy of Intranasal Fentanyl at Reducing Pain During Abscess Incision and Drainage (I&D) in Children

Pain | Abscess

United States
Wake Forest University
EKR Therapeutics, Inc

Terminated

Low Dose Extended-release Epidural and Lumbar Plexus Block Compared to Lumbar Plexus Block for Total Hip Resurfacing

Hip Arthroplasty

United States

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