Search clinical trials for: Placebo to Metformin

Total 61890 results

Tanta University

Completed

Metformin as Adjuvant Therapy in Obese Knee Osteoarthritis Patients

Knee Osteoarthritis

Egypt
The University of Hong Kong

Not yet recruiting

Metformin to Prevent Preterm Birth in Twin Pregnancy (TwinMet)

Pregnancy Complications | Preterm Birth | Drug Effect | Pregnancy Preterm | Metformin | Twin; Complicating Pregnancy | Premature Obstetric Labor
Hellenic Institute for the Study of Sepsis

Unknown

Incretin Hormones in Type 1 Diabetes Mellitus;Effect of Metformin Treatment (INCREDIBLE-M)

Type 1 Diabetes Mellitus

Greece
Centre for Addiction and Mental Health

Completed

Metformin in Co-morbid Diabetes or Prediabetes and Serious Mental Illness

Diabetes Mellitus, Type 2 | Schizophrenia

Canada
Milton S. Hershey Medical Center
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Lifestyle Intervention and Metformin for Women With Polycystic Ovary Syndrome (PCOS)

Polycystic Ovary Syndrome

United States
Jaeb Center for Health Research
Juvenile Diabetes Research Foundation

Completed

Insulin Clamp Ancillary Study for Assessment of Insulin Resistance

Type 1 Diabetes

United States
Amgen

Completed

AMG 151 Amgen Protocol Number 20100761

Diabetes Mellitus

United States, Puerto Rico, Poland, Estonia, Czech Republic
Massachusetts General Hospital
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Lifestyle Modification and Metformin Use in the Treatment of HIV

HIV Infections | Metabolic Syndrome X

United States
Laboratorios Silanes S.A. de C.V.
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran

Unknown

Efficacy Study of Metformin Glycinate on Postprandial Lipemia

Type 2 Diabetes

Mexico
Boehringer Ingelheim

Completed

BI 113608 Administered as Tablets Twice Daily Over 4 Weeks in Patients With Chronic Obstructive Pulmonary Disease Associated With Chronic Bronchitis

Pulmonary Disease, Chronic Obstructive

Germany
Dong Wha Pharmaceutical Co. Ltd.

Completed

Pharmacokinetic Profiles of Metformin With DW1029M (PMD)

Healthy

Korea, Republic of
Lassen Therapeutics Inc.

Recruiting

A Study to Evaluate the Efficacy and Safety of LASN01 in Patients With Thyroid Eye Disease

Eye Diseases | Endocrine System Diseases | Thyroid Eye Disease | Graves Ophthalmopathy | Orbital Diseases | Thyroid Associated Ophthalmopathy | Graves Orbitopathy | Proptosis

United States, United Kingdom, Spain
AstraZeneca

Completed

Study To Evaluate 24 Hour Blood Sugar Control (24-hour Mean Weighted Glucose) In Subjects That Are Taking Saxagliptin 5 mg Added Onto Metformin XR 1500 XR mg Compared To Subjects Taking Metformin XR 1500 mg Up-titrated To Metformin XR 2000 mg

Type 2 Diabetes

United States, Argentina, Mexico, Israel
University of Guadalajara

Completed

Effect of Propolis or Metformin Administration on Glycemic Control in Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

Mexico
Brii Biosciences Limited

Completed

A Study of BRII-297 in Healthy Adult Subjects

Postpartum Depression

Australia
Elaine Chow
Merck KGaA, Darmstadt, Germany

Not yet recruiting

High FODMAP Diet With Metformin in preDM

PreDiabetes | Impaired Glucose Tolerance

Hong Kong
Merck Sharp & Dohme LLC

Completed

Safety and Efficacy of Grazoprevir (MK-5172) + Elbasvir (MK-8742) in Participants With Chronic Hepatitis C and Chronic Kidney Disease (MK-5172-052) (C-SURFER)

Hepatitis C Virus
Susanna Naggie, MD
Vanderbilt University Medical Center; National Center for Advancing Translational...

Active, not recruiting

ACTIV-6: COVID-19 Study of Repurposed Medications - Arm G (Metformin)

Covid19

United States
Mansoura University

Completed

Efficacy of Metformin as Preventive Treatment in Paclitaxel Induced Peripheral Neuropathy in Breast Cancer Patients

Breast Cancer | Peripheral Neuropathy

Egypt
Ozmosis Research Inc.
Breast Cancer Research Foundation

Completed

A Trial of Standard Chemotherapy With Metformin (vs Placebo) in Women With Metastatic Breast Cancer

Metastatic Breast Cancer

Canada
Wayne State University

Withdrawn

Insulin Signaling in Skeletal Muscle

Insulin Sensitivity
Mayo Clinic
Alliance for Clinical Trials in Oncology

Terminated

Metformin as a Chemoprevention Agent in Non-small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung | Lung Neoplasms

United States
National Institute of Diabetes and Digestive and...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Diabetes Prevention Program

Glucose Intolerance | Diabetes Mellitus, Non-Insulin-Dependent

United States
Assistance Publique - Hôpitaux de Paris
ANRS, Emerging Infectious Diseases

Terminated

Primary Prevention Hepatocellular Carcinoma by Metformin (METFOVIR)

Hepatocellular Carcinoma | Hepatitis C, Chronic | Cirrhosis

France
Bristol-Myers Squibb

Completed

Safety Study of BMS-823778 in Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2

Canada, Australia, United States
Daiichi Sankyo, Inc.

Completed

Randomized, Placebo-controlled, 2 Period, Single-blind, Sequential, Multiple Ascending Dose Study

Type 2 Diabetes Mellitus

United States
Zagazig University

Completed

L-carnitine and Metformin in Obese PCOS Women.

PCOS

Egypt
ConjuChem

Terminated

Dose-Ranging Study to Evaluate Efficacy and Safety of Weekly CJC-1134-PC in Patients With T2DM on Metformin Monotherapy

Type 2 Diabetes Mellitus (T2DM)

United States, Canada
Evidem Consultores SL
Boehringer Ingelheim; Merck Serono International SA; European Commission

Unknown

Prevention of Microvascular Complications in Prediabetes e-PREDICE Study (ePREDICE)

PreDiabetes

Spain
Boehringer Ingelheim
Eli Lilly and Company

Completed

Linagliptin and Metformin Versus Linagliptin in Newly Diagnosed, Untreated Type 2 Diabetes

Diabetes Mellitus, Type 2

United States, Canada, India, Israel, Malaysia, Mexico, Philippines, Puerto Rico, Russian Federation, Sri Lanka, Thailand, Ukraine
National Cancer Institute (NCI)

Active, not recruiting

Metformin Hydrochloride in Preventing Oral Cancer in Patients With an Oral Premalignant Lesion

Hyperplasia | Oral Cavity Carcinoma | Oral Leukoplakia | Erythroplakia

United States, Canada
EMS

Not yet recruiting

Efficacy and Safety of Madalena Association in the Treatment of Type II Diabetes Mellitus

Type 2 Diabetes Mellitus
GlaxoSmithKline

Completed

A Safety, Tolerability, Pharmacokinetics (PK) and Target Engagement (TE) Study of GSK3858279 in Healthy Participants and Evaluation of the Efficacy of Repeat Doses in Participants With Osteoarthritis (OA)

Pain, Inflammatory

United Kingdom, Germany, Poland
Merck Sharp & Dohme LLC

Completed

Addition of Omarigliptin (MK-3102) to Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Combination Therapy With Glimepiride and Metformin (MK-3102-022)

Type 2 Diabetes Mellitus
Eli Lilly and Company

Completed

A Study in Participants With Type 2 Diabetes Mellitus (AWARD-3)

Diabetes Mellitus, Type 2

United States, Brazil, India, Puerto Rico, Romania, Poland, Germany, Croatia, Korea, Republic of, Mexico, United Kingdom, South Africa, Spain, Canada, Argentina, Czech Republic, Finland, France, Slovakia
Laboratorios Silanes S.A. de C.V.

Completed

Tolerability and Pharmacokinetics of Metformin and Metformin Extended Release (ER)

Healthy

Mexico
Novo Nordisk A/S

Completed

Single Dose Pharmacokinetics of Repaglinide, Metformin and Combination Tablet in Fed Healthy Volunteers

Diabetes Mellitus, Type 2 | Diabetes

United States
Novo Nordisk A/S

Completed

Comparison of Repaglinide and Metformin Combination Tablet Versus Repaglinide and Metformin as Separate Tablets in Healthy Volunteers

Healthy | Diabetes

China
University of California, Los Angeles

Not yet recruiting

Effect of Metformin, a Drug Used to Treat Diabetes, vs Placebo

Obesity | NIDDM

United States
Hvidovre University Hospital
University of Copenhagen

Terminated

Incretin Secretion in Women With Polycystic Ovary Syndrome (PCOS)

Polycystic Ovary Syndrome
Response Pharmaceuticals

Completed

A Comparison of SLx-4090 in Combination With Metformin Versus Metformin Therapy Alone in Patients With Type 2 Diabetes

Type 2 Diabetes

United States
University of Colorado, Denver
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Feasibility Study of Metformin Therapy in ADPKD

Polycystic Kidney, Autosomal Dominant

United States
University Hospital, Gentofte, Copenhagen

Completed

Incretin Effect in PCOS Women

Polycystic Ovary Syndrome

Denmark
Rowan University
University of Pennsylvania; FRAXA Research Foundation

Unknown

Metformin in Patients With Fragile X

Fragile X Syndrome

United States
CymaBay Therapeutics, Inc.

Terminated

Evaluate Safety and Effectiveness of MBX-102 in Type 2 Diabetes Patients With Poor Glycemic Control on Metformin

Type 2 Diabetes Mellitus

United States, India
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of the Safety and Effectiveness of a R256918 in Patients With Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes Mellitus | Endocrine System Diseases | Nutritional and Metabolic Diseases

United Kingdom, Germany, Belgium, Poland, India, Finland, Sweden, Netherlands, Russian Federation, Norway, Denmark
LG Life Sciences

Completed

BE Study of the Combinations of Gemigliptin 50mg and Metformin HCl Extended Release 1000mg in Comparison to Each Component Administered Alone

Healthy

Korea, Republic of
GlaxoSmithKline

Completed

Rosiglitazone-Metformin Combination Versus Metformin-Sulfonylurea Combination On Beta-Cell Function In Type 2 Diabetes

Type 2 Diabetes Mellitus
Centre d'Etudes et de Recherche pour l'Intensification...

Completed

Galvus (Vildagliptin) vs Placebo in Combination With Metformin and Insulin

Type 2 Diabetes

France
Genentech, Inc.

Completed

A Study of Vismodegib (GDC-0449, Hedgehog Pathway Inhibitor) As Maintenance Therapy in Patients With Ovarian Cancer in a Second or Third Complete Remission

Ovarian Cancer

Search clinical trials for: Placebo to Metformin

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