Clinical Trials Sponsored by Aprofol AG

Total 2387 results

Aesculap AG

Terminated

Sternal Closure With STERNUMFIX in Patients With High Risk (STEPHIX)

Sternum Wound Infection | Nonunion of Fracture of Sternum

Germany, Switzerland
4SC AG

Completed

4SC-201 (Resminostat) in Advanced Colorectal Carcinoma (SHORE)

Advanced Colorectal Carcinoma

Germany
Biotronik AG

Terminated

The Treatment of Coronary Artery Lesions Using the PRO-Kinetic Energy Cobalt-Chromium, Bare-Metal Stent (BIOHELIX-II)

Coronary Artery Disease

Netherlands, Switzerland
Biotronik AG

Completed

Self Expanding Nitinol Stent Versus Percutaneous Transluminal Arterial Angioplasty (PTA) With Optional Bailout Stenting in Case of PTA Failure in Patients With Symptomatic Critical Limb Ischemia or Severe Intermittent Claudication (EXPAND) (EXPAND)

Severe Intermittent Claudication | Patients With Symptomatic Critical Limb Ischemia

Germany
Biotronik AG

Completed

PROGRESS-AMS 1.0 Clinical Long Term Follow-Up

Long Term Safety of the AMS 1.0

Switzerland, Germany, Australia, Belgium, Netherlands
Biotronik AG

Completed

First in Man Trial - BIOSOLVE-I (BIOSOLVE-I)

de Novo Lesions in Native Coronary Arteries

Netherlands, Switzerland, Germany, Belgium
Bitop AG

Completed

Non Interventional Study (NIS) Regarding the Application of Ectoin Mund- & Rachenspray in Patients With Acute Laryngitis and/or Acute Pharyngitis

Acute Pharyngitis | Acute Laryngitis

Germany
MorphoSys AG

Completed

Phase Ib Study to Evaluate MOR103 in Multiple Sclerosis

Multiple Sclerosis

Germany, Poland, United Kingdom
NeMoDevices AG

Completed

A New Minimal-invasive Brain Tissue Probe Applying Near Infrared Spectroscopy

Spontaneous Subarachnoid Hemorrhage

Germany
4SC AG

Completed

Resminostat (4SC-201) in Relapsed or Refractory Hodgkin's Lymphoma (SAPHIRE)

Hodgkin's Lymphoma

Poland, Czech Republic, Romania
Biotronik AG

Completed

First in Man Experience With a Drug Eluting Stent in De Novo Coronary Artery Lesions (BIOFLOW-I)

Coronary Artery Disease

Romania
Aesculap AG

Completed

Comparison of Rotating vs. Fixed Platform of the COLUMBUS Knee Prosthesis

Osteoarthritis | Rheumatoid Arthritis | Post-traumatic; Arthrosis

Germany
Biotronik AG

Completed

BIOFLOW-INDIA Safety and Clinical PerFormance of the Drug Eluting ORSIRO Stent in Single de Novo Coronary Artery Lesions

Coronary Artery Disease

India
Biotronik AG

Completed

MULTIcentric BElgium/NEtherlands PRO-Kinetic Safety and Efficacy Study (MULTIBENE)

Coronary Artery Disease
Bitop AG

Completed

Non Interventional Study to Evaluate the Efficacy and Tolerability of Ectoin Containing Ophthalmic Solution

Dry Eye Syndromes

Germany
Medinova AG

Completed

Clinical Study of Vaginal Lactobacilli and Estriol (Gynoflor®) for Atrophic Vaginitis in Breast Cancer Patients (Gynoflor)

Atrophic Vaginitis

Belgium, Germany
Sensimed AG

Completed

SENSIMED Triggerfish® in Sitting and Supine Position

Healthy Subjects

Israel
4SC AG

Completed

SC12267 (4SC-101) in Combination With Methotrexate in Patients With Rheumatoid Arthritis (COMPONENT)

Rheumatoid Arthritis

Bulgaria, Czech Republic, Poland, Romania
Syntellix AG

Completed

Comparative Study of Osteosynthesis for Chevron Osteotomy of Hallux Valgus Using Degradable Versus Non-degradable Metallic Device

Hallux Valgus

Germany
Brahms AG

Completed

Investigation of the Biomarker Copeptin in Patients With Acute Myocardial Infarction (CHOPIN)

Acute Coronary Syndromes

United States
SkyePharma AG

Completed

Comparison of New Combination Inhaler (FlutiForm HFA MDI 100/10 µg) Versus Fluticasone and Formoterol Administered Alone, and Placebo, in Patients With Asthma

Asthma

United States, Canada
SkyePharma AG

Completed

New Combination Inhaler (FlutiForm HFA MDI 100/10 µg and 250/10 µg) Versus Fluticasone and Formoterol Administered Alone, and Placebo in Patients With Moderate to Severe Asthma

Asthma

United States, Puerto Rico
SkyePharma AG

Completed

Comparison of New Combination Inhaler (FlutiForm HFA MDI 100/10 µg) Versus Fluticasone & Formoterol Administered Alone in Patients With Asthma

Asthma

United States, Canada
4SC AG

Completed

SC12267 (4SC-101) for Treatment of Patients With Inflammatory Bowel Disease (ENTRANCE)

Inflammatory Bowel Disease (IBD)

Germany, Bulgaria, Romania
Sensimed AG

Completed

Central Corneal Thickness With SENSIMED Triggerfish (09/08)

Ocular Hypertension | Glaucoma

Germany
Affiris AG

Completed

AD01 Follow up Extension Visit

Alzheimer´s Disease

Austria
Affiris AG

Completed

Tolerability and Safety of Subcutaneous Administration of Affitope AD01 in Mild to Moderate Alzheimer's Disease

Alzheimer's Disease

Austria
ESBATech AG

Completed

Ocular Biodistribution Study for Topically Applied ESBA105

Cataract

Switzerland
Affiris AG

Completed

Long-term Safety and Tolerability of AFFITOPE AD01

Alzheimer's Disease

Austria
IDEA AG

Completed

Safety and Efficacy of Two Dosages of Diractin® in Osteoarthritis (OA)

Osteoarthritis of the Knee

Poland, United Kingdom, Czech Republic, Germany
IDEA AG

Completed

Multi-Centre, Open-Label, Two Segment, Study Comparing Plasma Pharmacokinetics of Ketoprofen in Diractin® Alone to Diractin® Applied Concomitant With Heat or Moderate Exercise

Pharmacokinetic

Germany
IDEA AG

Completed

IDEA-033 Open Label Study

Joint Pain | Musculoskeletal Pain | Stiffness | Soft Tissue Inflammation in Designated Target Area(s)

Germany
Aesculap AG

Completed

Clinical Use of an Absorbable Coated Suture Material in Surgery (Safil)

Gastrointestinal Diseases | Laparotomy | Anastomosis, Surgical | Absorbable, Coated Sutures

Hungary
elbion AG

Terminated

ELB245 for 12 Weeks Versus 4mg Tolterodine in Patients With Incontinent Overactive Bladder (OAB)

Overactive Bladder | Urinary Incontinence

Sweden, Germany, Poland
Weleda AG

Unknown

Bryophyllum vs. Nifedipine

Tocolysis

Switzerland
elbion AG

Terminated

ELB139 Given Orally to Patients With Concurrent Panic Disorder, Challenged by CO2 Inhalation After a Single Dose and One Week of Treatment

Panic Disorder

Germany, Netherlands
KeyBioscience AG
Eli Lilly and Company; Profil Institut für Stoffwechselforschung GmbH; Nordic...

Terminated

A Clinical Study to Evaluate the Safety, Tolerability, PK, PD, and Efficacy of KBP-089 in Patients With T2DM

Type II Diabetes Mellitus

Germany
Cellerys AG
Novartis; Tetec AG; Scope International AG; Jung Diagnostics GmbH

Not yet recruiting

Peptide-coupled Red Blood Cells for the Treatment of Multiple Sclerosis (RED4MS)

Relapsing-remitting Multiple Sclerosis (RRMS)
Tetec AG
Winicker Norimed GmbH; Aesculap AG

Active, not recruiting

Non-interventional Study With NOVOCART® 3D for the Treatment of Cartilage Defects of the Knee in Pediatric Patients (JUNOVO)

Cartilage Disease

Germany
Tetec AG
Winicker Norimed GmbH; Aesculap AG

Completed

Non-interventional Study With NOVOCART® Inject in the Reconstruction of the Knee Cartilage Defects (RENOVO)

Cartilage Disease

Germany
SpineWelding AG
ISS integrated Scientific Services AG

Terminated

A Feasibility Study to Evaluate the TURRIS Facet Fusion System in Lumbar Spinal Surgery

Spinal Disease

Switzerland
Ypsomed AG
Diabetes Center Berne Research AG

Completed

YpsoPump Occlusion Detection Algorithm: Collection of Real-world Data for In-silico Evaluation of a New Software Algorithm to Refine Occlusion Detection in Subjects With Type 1 Diabetes Using Continuous Subcutaneous Insulin Infusion

Diabetes Mellitus, Type 1

Germany, Switzerland
Tetec AG
Winicker Norimed GmbH; Aesculap AG

Completed

Non-interventional Study With NOVOCART® Basic in Patients Treated for Cartilage Defects in the Knee With MAC (NBasic)

Cartilage Diseases

Germany, Switzerland
Anjali Raja Beharelle
MediService AG

Enrolling by invitation

Collabree: A Remote Intervention to Improve the Regularity of Medication Intake

Hypertension | Medication Adherence

Switzerland
University Hospital Tuebingen
BASF; AUDI AG; BMW AG; Dachser Intelligent Logistics; Daimler AG; Deutsche Post AG; Iturri... and other collaborators

Completed

Work Physiological-Biomechanical Analysis of a Passive Exoskeleton to Support Occupational Lifting and Flexing Processes (ADVANCE)

Passive Upper-limb Exoskeleton

Germany
Profil Institut für Stoffwechselforschung GmbH

Terminated

Effects of Victoza® Versus Lyxumia® on Gastroesophageal Reflux, Gastric Emptying and Gastric Acid Secretion

Diabetes Mellitus

Germany
Profil Institut für Stoffwechselforschung GmbH

Completed

A Trial Investigating the Influence of Injection Speed and Volume on the Perception of Subcutaneous Injection Pain

Diabetes Mellitus

Germany
iOMEDICO AG
Bristol-Myers Squibb; Roche Pharma AG

Completed

Clinical Research Platform on Decision Making and Clinical Impact of Biomarker-Driven Precision Oncology (INFINITY)

Advanced Solid Tumors or Hematologic Malignancies

Germany
MoonLake Immunotherapeutics AG

Recruiting

A Study to Evaluate the Efficacy and Safety of Subcutaneous Sonelokimab Compared With Placebo in Adult Participants With Moderate to Severe Hidradenitis Suppurativa

Hidradenitis Suppurativa

United States
Alvotech Swiss AG

Recruiting

Pilot Study of AVT16 in Healthy Adult Subjects

Healthy

New Zealand

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