Clinical Trials Sponsored by AstraZeneca

Total 4286 results

AstraZeneca

Terminated

Study of Anastrozole +/- AZD8931 in Postmenopausal Women With Endocrine Therapy Naive Breast Cancer (MINT)

Neoplasms | Breast Cancer | Breast Neoplasms

Brazil, Czech Republic, Korea, Republic of, Mexico, Peru, Poland, Russian Federation, South Africa, United Kingdom, Philippines, Ukraine, Finland, Canada, Taiwan, India, Thailand, United States, Japan
AstraZeneca

Completed

Proof of Concept Study of Cognitive Improvement in Patients With Alzheimer's Disease (Sirocco)

Alzheimer Disease

Bulgaria, Czech Republic, Russian Federation, United Kingdom, Germany, Romania, Canada, Austria, Belgium, Spain
AstraZeneca

Completed

Study to Assess Safety and Efficacy of Ticagrelor (AZD6140) Versus Clopidogrel in Asian/Japanese Patients With Non-ST or ST Elevation Acute Coronary Syndromes (ACS)

Acute Coronary Syndrome | Percutaneous Coronary Intervention

Korea, Republic of, Japan, Taiwan
AstraZeneca

Completed

Assessment of Low-dose ASA Discontinuation Risk Associated With Concomitant PPI Use During the First Year of ASA Therapy

Cardiovascular Prevention

Spain
AstraZeneca

Completed

A Retrospective Swedish Cohort Study on Health Outcomes, Life Expectancy, Resource Use and Costs in Patients With a History of Myocardial Infarction and Additional Risk Factors for Atherothrombosis (HELICON)

Acute Coronary Syndrome

Sweden
AstraZeneca

Completed

To Assess the Effect of Rifampicin on the Pharmacokinetics of Selumetinib in Healthy Male Volunteers

Solid Tumours

United States
AstraZeneca

Completed

A Phase I Study in Healthy Volunteers to Assess the Effect of Cytochrome3A4 (CYP3A4) Inhibitors (Diltiazem and Itraconazole) on the Pharmacokinetics (PK) of AZD3293 and the Effects of AZD3293 on the Pharmacokinetics of Midazolam, a Cytochrome 3A4 and Cytochrome 3A5 (CYP3A4/CYP3A5) Substrate (AZD3293DDI)

Healthy Volunteers | Pharmacologic Action

United States
AstraZeneca

Completed

Study to See if Platelet Transfusion Stop or Lessen the Effect of the Drug on Platelets

Inhibition on Platelet Aggregation

United States
AstraZeneca

Terminated

JUPITER - Crestor 20mg Versus Placebo in Prevention of Cardiovascular (CV) Events

Elevated High-sensitivity C-Reactive Protein (hsCRP)

United States, Brazil, Bulgaria, Poland, Russian Federation, South Africa, United Kingdom, Germany, Estonia, Romania, Denmark, Netherlands, Norway, Canada, Mexico, Belgium, Israel, Puerto Rico, Colombia, Argentina, Venezuela, Panama, Urugu... and more
AstraZeneca

Completed

The Study Will Evaluate the Effect of AZD8683 in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease (COPD)

Poland
AstraZeneca

Completed

New Breath Actuated MDI Symbicort Compared to Symbicort pMDI and Budesonide pMDI for 12 Weeks Twice a Day (BAI)

Asthma

United States, Bulgaria, Hungary, Russian Federation
AstraZeneca

Completed

14729-D9831C00002- 1 Month Biopsy Study (Biopsy)

Chronic Obstructive Pulmonary Disease

United Kingdom, Germany, Netherlands
AstraZeneca

Completed

One Month Dose Response Study of AZD1981 in Asthma Patients Uncontrolled on Inhaled Steroids (OLIVE)

Asthma

Poland, Argentina, Brazil, Costa Rica
AstraZeneca

Completed

Efficacy of AZD3199 in Chronic Obstructive Pulmonary Disease (COPD) Patients (GLAD)

COPD

Bulgaria, Poland, Russian Federation, Japan, Canada
AstraZeneca

Completed

Outcome Study Following Reimbursement Changes in the Use of Fixed Combination Inhalers in Patients With Asthma or Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease | Asthma

Sweden
AstraZeneca

Completed

Prilosec Bioequivalence Study in Healthy Volunteers

Bioequivalence, AUC, Cmax, Pharmacokinetics

United States
AstraZeneca

Completed

Investigation of Efficacy, Safety and Tolerability of Once and Twice Daily Doses of AZD1981 in Asthmatic Patients (Sweapea)

Asthma Patients

United States, Mexico, Russian Federation, South Africa, Romania, Ukraine, Japan, Argentina, Slovakia, Brazil
AstraZeneca

Completed

A Study in Asthmatic Children (6 to <12 Yrs) Comparing Single Doses of Formoterol and Foradil® Evaluating Efficacy (CHASE 2)

Asthma

United States, South Africa, Hungary, Bulgaria, Czech Republic, Poland
AstraZeneca

Terminated

Safety and Efficacy Study of ONGLYZA (Saxagliptin) Under Conditions of Actual Use (ONGLYZA PMS)

Type 2 Diabetes Mellitus

Philippines
AstraZeneca

Completed

A Single Dose Study to Assess the Safety, Effects, and Blood and Urine Drug Levels of AZD3293 in Healthy Subjects

Healthy Elderly Volunteers | Healthy Young Volunteers

United States
AstraZeneca

Completed

Epidemiology Study in Postmenopausal Women With Estrogen Receptor Positive Breast Cancer

Hormon Receptor Positive Breast Cancer

Serbia
AstraZeneca

Completed

Multicenter Study of Antimicrobial Resistance of Gram-positive and Gram-negative Clinical Strains to Ceftaroline and Other Antimicrobials in Russia (CERBERUS)

Bacterial Skin Diseases

Russian Federation
AstraZeneca

Completed

Multi-centre Study to Assess the Efficacy and Safety of AZD5423 in COPD Patients on a Background Therapy of Formoterol

Chronic Obstructive Pulmonary Disease (COPD)

Bulgaria, France, Italy, Poland, Russian Federation, Ukraine, Hungary, Slovakia
AstraZeneca

Completed

Symbicort Turbuhaler 30/60 Specific Clinical Experience Investigation (ENSURE)

Bronchial Asthma

Japan
AstraZeneca

Completed

Study to Evaluate the Safety and Effects AZD0530 on Prostate and Breast Cancer Subjects With Metastatic Bone Disease

Breast Cancer | Bone Neoplasms | Prostate Cancer

United States, United Kingdom, Sweden, Norway, Canada, Portugal, Denmark, Spain
AstraZeneca

Completed

Prevalence Study and Regular Practice Among General Practitioners in Populations at Risk of Chronic Obstructive Pulmonary Disease (COPD) in Latin America (PUMA PROJECT)

Chronic Obstructive Pulmonary Disease

Venezuela, Colombia, Argentina, Uruguay
AstraZeneca

Completed

A Study to Assess the Bioequivalence of R406 in Healthy Volunteers When Given 100mg and 150 mg of Fostamatinib (Fosta BE)

Healthy Volunteers

United States
AstraZeneca

Completed

Study of AZD8931 in Patients With Advanced Solid Malignancies

Advanced Solid Malignancies

Russian Federation, Germany
AstraZeneca

Completed

Evaluation of the Pharmacokinetics and the Pharmacodynamics of Different Dry Powder Inhalation Formulations of AZD3199 in Patients With Asthma

Asthma

Sweden
AstraZeneca

Completed

To Investigate Safety, Tolerability and Pharmacokinetics of TC-5214 in Healthy Male Japanese Subjects

Healthy
AstraZeneca

Completed

A Prospective,Open-label Study of Anastrozole in Post-menopausal Women With Hormone Sensitive Advanced Breast Cancer

Breast Cancer
AstraZeneca

Withdrawn

A Drug-Drug Interaction Study Between AZD9668 and Warfarin to Study the Effect of AZD9668 on the Metabolism and Effect of Warfarin

Pharmacokinetics | Pharmacodynamics

Sweden
AstraZeneca

Terminated

Lipid-lowering Therapy for Secondary Prevention in Patients Undergoing Elective Percutaneous Coronary Intervention (PCI)

Coronary Artery Disease

Slovenia
AstraZeneca

Completed

AZD7268 Single Ascending Dose Study in Healthy Japanese Subjects (JSAD)

Healthy

United States
AstraZeneca

Withdrawn

Study in Healthy Males to Assess Distribution, Metabolism, and Excretion of Radio-labelled AZD9742 Administered as a 2-hour Infusion

Healthy

United States
AstraZeneca

Terminated

Seroquel in Acute Mania: Study to Investigate if Valproate Add-On Therapy is Superior to Quetiapine Monotherapy in Acutely Manic Patients

Bipolar Disorder

Denmark
AstraZeneca

Completed

Liver Safety Under Upfront Arimidex vs Tamoxifen (HEART)

Breast Cancer

China
AstraZeneca

Completed

Centralised Pan-Algerian Survey on the Undertreatment of Hypercholesterolemia (CEPHEUS)

Hypertension | Cardiovascular Disease | Diabetes | Peripheral Arterial Disease | Hypercholesterolemia | Coronary Heart Disease
AstraZeneca

Completed

Study of Selumetinib (AZD6244)(ARRY-142886) in Combination With Irinotecan in Previously Treated Patients With Colorec

Colorectal Cancer

United States
AstraZeneca

Completed

ZD4054 (Zibotentan) in Pain-free or Mildly Symptomatic Patients With Prostate Cancer and Bone Metastases Who Have Rising Serum Prostate Specific Antigen (PSA)

Prostate Cancer

Sweden, United States, Australia, France, United Kingdom, Poland, Finland, Netherlands, Norway, Belgium, Canada, Indonesia, Denmark, Switzerland
AstraZeneca

Completed

Seroquel Switching Study: Feasibility of Switching Any Antipsychotic Treatment to Seroquel in Patients With Schizophrenia

Schizophrenia

Hungary, Finland, Canada, Germany
AstraZeneca

Completed

Quetiapine Fumarate (SEROQUEL) Compared to Placebo in the Treatment of Children & Adolescents With Bipolar I Mania (ANCHOR 149)

Bipolar Disorder

United States
AstraZeneca

Completed

Study of 24-hour Intragastric pH Profiles of Esomeprazole 40 mg and Lansoprazole 30 mg in Healthy Volunteer Subjects

Healthy

United States
AstraZeneca

Completed

A Comparison of Seroquel vs. Risperidone in Schizophrenia

Schizophrenia

United States
AstraZeneca

Completed

Seroquel on Glucose Metabolism

Schizophrenia

Bulgaria, Czech Republic, South Africa, United Kingdom, Germany, Hungary, Romania, Slovakia, Norway
AstraZeneca

Completed

Relapse Prevention, RoW: Study to Evaluate Prevention of Relapse in Patients in Stable Chronic Schizophrenia Receiving Either Seroquel or Placebo

Schizophrenia

Bulgaria, Poland
AstraZeneca

Completed

Atypical Antipsychotics in the Treatment of Affective Symptoms of Schizophrenia in Hungary (AFFECT)

Schizophrenia | Affective Symptoms

Hungary
AstraZeneca

Completed

Study to Assess Effect of Cyclosporine on the Blood Levels of Ticagrelor

Healthy

United States
AstraZeneca

Terminated

Patterns of Care in Hormone-receptor Positive, Advanced Breast Cancer

Breast Cancer

Brazil
AstraZeneca

Completed

Non-interventional Study: Real-life Use of Atypical Antipsychotics in Acute Inpatient Management of Schizophrenia

Schizophrenia | Acute Psychotic Episode

Hungary, Latvia, Romania

3

Subscribe