Clinical Trials Sponsored by Milestone Pharmaceuticals Inc.

Total 4991 results

Astex Pharmaceuticals, Inc.

Completed

A Study to Investigate the Effect of CYP3A4 Inhibition on the Single Dose Pharmacokinetics of ASTX660 and the Effect of a Single Dose of ASTX660 on the Pharmacokinetics of the CYP3A4 Substrate Midazolam

Healthy Volunteer

United States
Apexian Pharmaceuticals, Inc.

Completed

A Study of APX3330 in Patients With Advanced Solid Tumors (APX3330)

Cancer

United States
Agios Pharmaceuticals, Inc.

Terminated

A Study of AG-636 in the Treatment of Subjects With Advanced Lymphoma

Lymphoma

United States
Afferent Pharmaceuticals, Inc.

Terminated

The Safety and Efficacy of Gefapixant (AF-219/MK-7264) in Female Participants With Interstitial Cystitis /Bladder Pain Syndrome (MK-7264-005)

Bladder Pain Syndrome

United States
Pacira Pharmaceuticals, Inc

Withdrawn

Phase 3, Randomized, Double Blinded, Active Controlled, Multicenter Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of EXPAREL Admixed With Bupi vs. Bupi Only Administered as Combined Sciatic and Adductor Canal Nerve Block for Postsurgical Analgesia in Lower Extremity Surgeries (STRIDE)

Bunion | Metatarsophalangeal Fusion | Midfoot Fusion | Hindfoot Fusion | Total Ankle Arthroplasty | Forefoot Surgery
EyePoint Pharmaceuticals, Inc.

Completed

Safety and Efficacy Study of a FAI Insert in Subjects With Chronic Non-infectious Posterior Uveitis

Panuveitis | Posterior Uveitis | Intermediate Uveitis

India
Paratek Pharmaceuticals Inc

Completed

IV or IV/PO Omadacycline vs. IV/PO Levofloxacin for the Treatment of Acute Pyelonephritis

Acute Pyelonephritis

Georgia, Latvia, Russian Federation, Ukraine
Rexahn Pharmaceuticals, Inc.

Terminated

Dose-Finding, Safety and Efficacy Study of RX-0201 Plus Everolimus in Metastatic Renal Cell Cancer

Metastatic Renal Cell Cancer

United States
NeuroBo Pharmaceuticals Inc.

Completed

Efficacy and Safety of Gemcabene in Patients With Homozygous Familial Hypercholesterolemia on Stable, Lipid-Lowering Therapy (COBALT-1)

Hypercholesteremia

United States, Canada, Israel
Tracon Pharmaceuticals Inc.

Completed

Trial of TRC105 and Pazopanib Versus Pazopanib Alone in Patients With Advanced Angiosarcoma (TAPPAS)

Advanced Angiosarcoma

United States, France, Italy, Austria, Germany, Poland, Spain, United Kingdom
EyePoint Pharmaceuticals, Inc.

Completed

Utilization and Safety of the Mk II Inserter and the Safety of the FAI Insert in Non-Infectious Uveitis (MkII)

Non-Infectious Uveitis

United States
MyMD Pharmaceuticals, Inc.

Completed

Single Ascending-dose Study to Evaluate Safety, Tolerability, and PK of MYMD1 in Healthy Male Adult Subjects

Undefined

United States
NeuroBo Pharmaceuticals Inc.

Completed

Efficacy and Safety of Gemcabene in Patients With Low HDL-C and Either Normal or Elevated Triglycerides

Hypercholesterolemia | Hypertriglyceridemia
NeuroBo Pharmaceuticals Inc.

Completed

Efficacy and Safety of Gemcabene in Hypercholesterolemic Patients as Monotherapy or in Combination With Atorvastatin

Hypercholesterolemia
NeuroBo Pharmaceuticals Inc.

Completed

The Effect of Gemcabene on Insulin Sensitivity in Nondiabetic Subjects

Insulin Sensitivity
NeuroBo Pharmaceuticals Inc.

Completed

Pharmacokinetics and Pharmacodynamics Study of Gemcabene in Healthy Volunteers

Hypercholesterolemia
NeuroBo Pharmaceuticals Inc.

Completed

Efficacy and Safety of Gemcabene in Hypercholesterolemic Patients on Stable Statin Therapy

Hypercholesterolemia
ACADIA Pharmaceuticals Inc.

Completed

A Study of Pimavanserin for the Treatment of Agitation and Aggression in Subjects With Alzheimer's Disease

Agitation and Aggression in Alzheimer's Disease

United States, Spain, Chile, France, United Kingdom
Agios Pharmaceuticals, Inc.

Completed

A Study to Evaluate AG-881 in Healthy Japanese and Non-Asian Participants

Healthy Volunteers

United States
Scilex Pharmaceuticals, Inc.

Completed

Adhesion Performance Study of Lidocaine Topical System 1.8% Compared to Lidocaine Patch 5% and Lidocaine Medicated Plaster 5% in Healthy, Adult, Human Subjects

Healthy

United States
Scilex Pharmaceuticals, Inc.

Completed

Adhesion of Lidocaine Topical System 1.8%

Healthy
Splash Pharmaceuticals, Inc.

Unknown

Safety and Efficacy Study of Daily SPL-108 Injections In Conjunction With Paclitaxel in Women With Ovarian Cancer

Ovarian Epithelial Cancer

United States
Aegerion Pharmaceuticals, Inc.

Completed

Study to Determine the Intra-subject Variability of Pharmacokinetics of Lomitapide in Healthy Subjects

Intra-subject Variability of Pharmacokinetics

United Kingdom
Astex Pharmaceuticals, Inc.

Completed

Effect of Food on Blood Levels of ASTX727

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Chronic Myelomonocytic Leukemia

United States
Atea Pharmaceuticals, Inc.

Completed

Study of AT-527 in Healthy and HCV-Infected Subjects

Hepatitis C | Hepatitis C, Chronic | Chronic Hepatitis C

Belgium, Moldova, Republic of
Idera Pharmaceuticals, Inc.

Completed

A Study of Intratumoral IMO-2125 in Patients With Refractory Solid Tumors (ILLUMINATE-101)

Melanoma | Refractory Solid Tumors

United States, Israel
Crinetics Pharmaceuticals Inc.

Completed

Mass Balance and Pharmacokinetics of [14C]-CRN00808 in Healthy Volunteers

Healthy Volunteers

Netherlands
Astex Pharmaceuticals, Inc.

Completed

A Study to Investigate the Safety and Efficacy of AT13387, Alone or in Combination With Imatinib, in Patients With GIST

Gastrointestinal Stromal Tumor (GIST)

United States
Astex Pharmaceuticals, Inc.

Withdrawn

Study of SGI-1776, a PIM Kinase Inhibitor, in Subjects With Relapsed/Refractory Leukemias

Relapsed/Refractory Leukemias

United States
Astex Pharmaceuticals, Inc.

Completed

Study to Assess the Safety of Escalating Doses of AT13387 in Patients With Metastatic Solid Tumors

Metastatic Solid Tumors

United States
Allist Pharmaceuticals, Inc.

Unknown

Safety, Tolerability, Pharmacokinetics and Anti-tumour Activity of Alflutinib in Advanced Non Small Cell Lung Cancer

NSCLC
Allist Pharmaceuticals, Inc.

Unknown

Efficacy and Safety of Alflutinib in Locally Advanced or Metastatic Non-Small Cell Lung Cancer Patients With T790M

Advanced NSCLC Patients With T790M

China
Ionis Pharmaceuticals, Inc.

Completed

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ISIS-APO(a)Rx in Participants With High Lipoprotein(a)

Elevated Lipoprotein(a)

Netherlands, United Kingdom, Denmark, Germany, Canada
Satsuma Pharmaceuticals, Inc.

Completed

A Phase I Study to Study the PK and Safety of Single Doses of STS101, DHE Injection and Nasal Spray in Healthy Subjects

Migraine | Migraine Without Aura | Migraine With Aura

United States
ACADIA Pharmaceuticals Inc.

Completed

Study to Evaluate the Efficacy and Safety of Adjunctive Pimavanserin in Major Depressive Disorder (CLARITY)

Adjunctive Treatment of Major Depressive Disorder

United States
AVEO Pharmaceuticals, Inc.

Completed

A Study to Compare Tivozanib (AV-951) to Sorafenib in Subjects With Advanced Renal Cell Carcinoma (TIVO-1)

Advanced Renal Cell Carcinoma

United States, Argentina, Bulgaria, Canada, Chile, Czechia, France, Hungary, India, Italy, Poland, Romania, Russian Federation, Serbia, Ukraine, United Kingdom
Agios Pharmaceuticals, Inc.

Completed

Study to Evaluate the Effect of Multiple Doses of Itraconazole and Rifampin on the Single-Dose Pharmacokinetics of Mitapivat Sulfate (AG-348) in Healthy Adult Participants

Healthy Volunteers

United States
Furiex Pharmaceuticals, Inc

Completed

Efficacy, Safety, and Tolerability of JNJ-27018966 (Eluxadoline) in the Treatment of Irritable Bowel Syndrome With Diarrhea

Irritable Bowel Syndrome

United States
Eloxx Pharmaceuticals, Inc.

Terminated

Safety, Tolerability, Pharmacokinetics of ELX-02 in Healthy Adult Volunteers

Genetic Diseases | Nonsense Mutations
Momenta Pharmaceuticals, Inc.

Completed

Evaluation of M118 in Percutaneous Coronary Intervention (EMINENCE) (EMINENCE)

Coronary Artery Disease (CAD)

United States, Canada
Ironwood Pharmaceuticals, Inc.

Completed

A Trial of IW-3718 for 8 Weeks in Patients With Symptomatic Gastroesophageal Reflux Disease (GERD)

Gastroesophageal Reflux Disease

United States
Agios Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Effect of AG-881 on the Pharmacokinetics of a Single Dose of Lamotrigine in Healthy Adults

Healthy Participants

United States
PhaseBio Pharmaceuticals Inc.

Completed

A Study to Assess the Safety, Tolerability, and Hemodynamic Response of PB1046 in Subjects With PAH

Pulmonary Arterial Hypertension

United States
Tonix Pharmaceuticals, Inc.

Completed

A 40-week Study to Evaluate TNX-102 SL 5.6 mg Taken Daily at Bedtime in Patients With PTSD (P306)

PTSD

United States
Supernus Pharmaceuticals, Inc.

Withdrawn

Classroom Study of SPN-812 in Children With ADHD

ADHD
Idera Pharmaceuticals, Inc.

Terminated

Phase 1/2 Dose Escalation Study in Patients With Relapsed or Refractory Waldenstrom's Macroglobulinemia (8400-401)

Waldenstrom's Macroglobulinemia

United States
Conatus Pharmaceuticals Inc.

Completed

Emricasan, a Caspase Inhibitor, for Evaluation in Subjects With Non-Alcoholic Steatohepatitis (NASH) Fibrosis (ENCORE-NF)

Liver Diseases | Fibrosis | Non-alcoholic Steatohepatitis

United States, Spain, Germany
Biohaven Pharmaceuticals, Inc.

No longer available

Expanded Access Protocol of BHV-0223 for Patients With Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis | ALS | Lou Gehrig Disease | Lou Gehrig's Disease | Lou-Gehrigs Disease | Motor Neuron Disease, Amyotrophic Lateral Sclerosis
Ionis Pharmaceuticals, Inc.

Completed

Efficacy and Safety of Inotersen in Familial Amyloid Polyneuropathy

Amyloidosis | Familial Amyloid Polyneuropathy | FAP | TTR | Transthyretin

New Zealand, United States, Spain, Argentina, Brazil, France, Germany, Italy, Portugal, United Kingdom
Navitor Pharmaceuticals, Inc.

Completed

Safety, Tolerability, PK and Efficacy of Single Doses of NV-5138 in Healthy Volunteers and Subjects With Treatment-Resistant Depression

Treatment Resistant Depression

United States

3

Subscribe