Clinical Trials Sponsored by Vaxxinity, Inc.

Total 35723 results

Liberating Technologies, Inc.
Vivonics, Inc.

Completed

Moisture Management Liner At-Home Evaluation

Amputation | Prosthesis | Prosthesis User | Amputation Stump | Amputees | Lower Limb Deformity

United States
LENZ Therapeutics, Inc
ORA, Inc.

Completed

Phase 3 Evaluation of the Safety and Efficacy of LNZ101 for the Treatment of Presbyopia (CLARITY)

Eye Diseases | Refractive Error | Presbyopia | Miosis | Near Vision

United States
Neovasc Inc.
Shockwave Medical, Inc.

Active, not recruiting

REDUCER-I: An Observational Study of the Neovasc Reducer™ System

Angina Pectoris | Chronic Stable Angina | Angina Pectoris, Stable

Netherlands, Spain, United Kingdom, Germany, Italy, Switzerland, Belgium, France, Austria
H3 Biomedicine Inc.
Eisai Inc.

Completed

Phase 1 Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of H3B-6527 in Participants With Advanced Hepatocellular Carcinoma

Liver Neoplasms | Hepatocellular Carcinoma | Advanced Hepatocellular Carcinoma | Liver Cancer | Hepatic Cancer | Hepatic Carcinoma

France, United States, Belgium, Spain, Taiwan, Korea, Republic of, Russian Federation, Canada, Italy, Singapore, United Kingdom
Astellas Pharma Inc
Seagen Inc.

Completed

A Study of Enfortumab Vedotin for Patients With Locally Advanced or Metastatic Urothelial Bladder Cancer (EV-201)

Urologic Neoplasms | Urinary Bladder Neoplasms | Carcinoma, Transitional Cell | Ureteral Neoplasms | Urothelial Cancer | Urethral Neoplasms | Renal Pelvis Neoplasms

United States, Korea, Republic of, Spain, France, Germany, Italy, Japan, Netherlands
ImmunoVaccine Technologies, Inc. (IMV Inc.)

Terminated

Maveropepimut-S (MVP-S) and Low-Dose CPA in Patients With Platinum-Resistant Ovarian Cancer (AVALON)

Platinum-resistant Epithelial Ovarian Cancer

United States, Canada, Puerto Rico
Citius Pharmaceuticals, Inc.
Therapeutics, Inc.

Completed

Safety and Efficacy of CITI-002 in Adult Patients With Moderate Grade Hemorrhoids

Hemorrhoids

United States
Novan, Inc.
Chiltern International Inc.

Completed

P3 Study in Acne Comparing Once Daily SB204 and Vehicle

Acne Vulgaris

United States
Checkable Medical Inc
Curebase Inc.

Completed

Clinical Performance of the Checkable Medical At-Home Strep A Test

Respiratory Tract Infections | Pharyngitis | Streptococcus Pyogenes Infection

United States
Eisai Inc.
PharmaBio Development Inc.

Terminated

E7080 in Combination With Carboplatin + Gemcitabine Versus Carboplatin + Gemcitabine Alone as Second Line Therapy in Patients With Platinum-Sensitive Recurrent Ovarian Cancer by CA125

Ovarian Cancer

United States
Taiho Oncology, Inc.
Quintiles, Inc.

Terminated

Phase 2 Study of TAC-101 Combined With Transcatheter Arterial Chemoembolization (TACE) Versus TACE Alone in Japanese Patients With Advanced Hepatocellular Carcinoma

Advanced Hepatocellular Carcinoma

Japan
Novan, Inc.
Chiltern International Inc.

Completed

P3 Long Term Safety Study of Once Daily SB204 in Acne

Acne Vulgaris

United States
SerenaGroup, Inc.
DSM Biomedical, Inc.

Completed

Effect of Meso Wound Matrix in the Treatment of DFUs

Diabetic Foot Ulcers (DFUs)

United States
Esperion Therapeutics, Inc.
Medpace, Inc.

Completed

Evaluation of ETC-1002 in Participants With Hypercholesterolemia and Hypertension

Hypertension | Hypercholesterolemia

United States
Allgenesis Biotherapeutics Inc.
ORA, Inc.

Completed

A Study of AG-80308 in Dry Eye Patients

Dry Eye Disease

United States
Eisai Korea Inc.

Completed

A Study of Pariet to Prevent Gastric and Duodenal Ulcer Associated With Low-aspirin in Korean Participants With a History of Gastric and Duodenal Ulcer

Duodenal Ulcer | Stomach Ulcer

Korea, Republic of
NeuroRx, Inc.
Target Health Inc.

Completed

NRX101 Glx Biomarker Validation Study (NRX-GLX)

Suicidal Ideation | Bipolar Depression

United States
Technoderma Medicines Inc.
Therapeutics, Inc.

Completed

A Phase 1 Study of TDM-105795 Topical Solution in Male Subjects With Androgenetic Alopecia (AGA) (AGA)

Alopecia, Androgenetic

United States
Eisai Inc.
PharmaBio Development Inc.

Completed

Study of Denileukin Diftitox in Participants With Stage IIIC and Stage IV Melanoma

Stage IV Melanoma | Stage IIIC Melanoma

United States
SerenaGroup, Inc.
Anacapa Technologies Inc

Completed

Randomized Double-Blind Controlled Clinical Trial

Chronic Wounds | Acute Wounds

United States
Eisai Korea Inc.

Completed

Open-label, Multi-center Trial of Zonisamide as Adjunctive Therapy in Patients With Uncontrolled Partial Epilepsy

Epilepsy

Korea, Republic of
Eisai Korea Inc.

Completed

Comparative Study of Zonisamide and Carbamazepine as an Initial Monotherapy: Efficacy and Safety Evaluation

Epilepsy

Korea, Republic of
Eisai Korea Inc.

Completed

Alzheimer's Disease Long-term Follow-up Study (ALF Study)

Alzheimer's Disease

Korea, Republic of
Seagen Inc.
Millennium Pharmaceuticals, Inc.

Completed

ECHELON-2: A Comparison of Brentuximab Vedotin and CHP With Standard-of-care CHOP in the Treatment of Patients With CD30-positive Mature T-cell Lymphomas (ECHELON-2)

Non-Hodgkin Lymphoma | T-Cell Lymphoma | Anaplastic Large-Cell Lymphoma

United States, Korea, Republic of, Spain, United Kingdom, Taiwan, Czechia, Hungary, France, Israel, Germany, Italy, Denmark, Australia, Poland, Romania, Canada
Nevakar, Inc.
Nevakar Injectables, Inc.

Completed

A Phase 2 Study to Evaluate Pregabalin and Acetaminophen Compared to Acetaminophen and Placebo in Subjects Undergoing Bunionectomy

Postoperative Pain

United States
Hawthorne Effect Inc.
HLNatural, Inc.

Completed

Upset Stomach Relief for Mild and Moderate Indigestion and Heartburn

Heartburn | Indigestion

United States
BRIM Biotechnology Inc.
ORA, Inc.

Completed

Safety and Efficacy of BRM421 for Dry Eye Syndrome Treatment

Dry Eye Syndrome

United States
Eisai Korea Inc.

Completed

A Study of Fycompa (Perampanel) in Korean Participants

Epilepsy

Korea, Republic of
ImmunoVaccine Technologies, Inc. (IMV Inc.)

Terminated

A Study of DPX-Survivac Vaccine Therapy in Patients With Recurrent Survivin-expressing DLBCL

Diffuse Large B-Cell Lymphoma

Canada
Seagen Inc.
Millennium Pharmaceuticals, Inc.

Completed

A Phase 3 Study of Brentuximab Vedotin (SGN-35) in Patients at High Risk of Residual Hodgkin Lymphoma Following Stem Cell Transplant (The AETHERA Trial)

Disease, Hodgkin

United States, United Kingdom, France, Romania, Poland, Italy, Bulgaria, Hungary, Russian Federation, Czechia, Spain, Germany, Serbia
Eisai Inc.
PharmaBio Development Inc.

Completed

E7050 in Combination With Sorafenib Versus Sorafenib Alone as First Line Therapy in Participants With Hepatocellular Carcinoma

Hepatocellular Carcinoma

Belgium, Italy, Spain, United States, Ukraine, United Kingdom
LifeSeasons Inc.
KGK Science Inc.

Completed

Investigating the Efficacy of Rest-ZZZ Formula in Healthy Participants With Difficulty Falling Asleep or Staying a Sleep

Healthy | Sleep

Canada
SerenaGroup, Inc.
LifeCuff Technologies Inc.

Withdrawn

Evaluating Remote Ischemic Conditioning (RIC) and Standard of Care vs. Sham Therapy and Standard Care

Diabetic Foot Ulcer
Eisai Korea Inc.

Completed

Study in Patients With Moderated to Severe Rheumatoid Arthritis Who Have Failed to Combination Therapy of Conventional Disease-modifying Antirheumatic Drugs (cDMARDs) to cDMARD Plus ANti-TNF Versus cDMARDs in Real World (HUMAN)

Arthritis, Rheumatoid

Korea, Republic of
NeuroActiva, Inc.
Biomed Industries, Inc.

Unknown

A Phase 3 Randomized Double Blind Efficacy and Safety Study of Oral Polio Vaccine and NA-831 for Covid-19 (OPV-NA831)

Covid19 | SARS-CoV-2 | SARS-CoV Infection | SARS (Severe Acute Respiratory Syndrome)

New Zealand, United States
Naked Biome, Inc.
Therapeutics, Inc.

Completed

A Study of the Safety, Engraftment, and Action of Multi-Dosed NB01 in Adults With Moderate Acne

Acne Vulgaris

United States
EndoCeutics Inc.
AMAG Pharmaceuticals, Inc.

Withdrawn

Effect of Intravaginal Prasterone on Symptoms of VVA in Women Under Treatment With an Aromatase Inhibitor for Breast Cancer

Vaginal Atrophy in Breast Cancer Patients
AIDP, Inc.
KGK Science Inc.

Completed

Evaluating Efficacy of Investigational Products on Spontaneous Bowel Movements in Healthy People With ≤ 3 Complete Weekly Spontaneous Bowel Movements

Healthy | Functional Constipation

Canada
AVEO Pharmaceuticals, Inc.
Biodesix, Inc.

Withdrawn

A Study of Ficlatuzumab With HiDAC and HiDAC Alone in Adults With Relapsed or Refractory Acute Myeloid Leukemia (CyFi2)

Acute Myeloid Leukemia
Eisai Korea Inc.

Completed

Study to Observe the Change in Microbiome in Human Derived Sample and the Relation With Clinical Response Before and After the Anti-TNF Treatment in IBD Patients (ETERNITY)

Inflammatory Bowel Disease

Korea, Republic of
Actavis Inc.
Watson Laboratories, Inc.

Completed

A Multi-center, Double-blind, Randomized Study, Comparing Clindamycin Phosphate Vaginal Cream 2% (Watson Laboratories, Inc.) to Clindesse® (Ther-Rx™, Clindamyin Phosphate Vaginal Cream 2%) and Both Active Treatments to a Placebo Control in the Treatment of Bacterial Vaginosis in Non-pregnant Women

BACTERIAL VAGINOSIS | Signs and Symptoms to be Evaluated and Recorded Include | Vaginal Discharge Color, Odor, and Consistency | Vulvovaginal Itching and Irritation (Subjective) Absent, Mild, Moderate, or Severe | Vulvovaginal Inflammation (Objective) Absent, Mild, Moderate, or Severe

United States, Dominican Republic, Puerto Rico
Actavis Inc.
Watson Laboratories, Inc.

Completed

Randomized, Double-blind, Multiple-site, Placebo-controlled, Parallel-design Study in Patients With Moderate to Severe Facial Erythema Associated With Rosacea

Rosacea

United States
Athenex, Inc.
TKL Research, Inc.

Completed

Single-Center Study Evaluating Systemic Exposure and Safety of KX2-391 Ointment 1% on the Face or Balding Scalp in Subjects With Actinic Keratosis

Actinic Keratoses

United States
HyGIeaCare, Inc.
Biostatistical Consulting, Inc.

Withdrawn

HyGIeaCare Procedure for Chronic Constipation

Constipation - Functional

United States
Esperion Therapeutics, Inc.
Medpace, Inc.

Completed

Evaluation of ETC-1002 vs Placebo in Patients Receiving Ongoing Statin Therapy

Hypercholesterolemia

United States
Daiichi Sankyo, Inc.
Medpace, Inc.

Completed

Drug-drug Interaction Study of Tivantinib (ARQ 197) With Omeprazole, S-warfarin, Caffeine, Midazolam, and Digoxin in Cancer Subjects

Solid Tumors

United States
Daiichi Sankyo, Inc.
Quintiles, Inc.

Completed

Comparison of Two Doses of Edoxaban Using Different Tests (Assays) and Clinical Outcomes

Atrial Fibrillation

Denmark, Hungary, Croatia, Serbia, Spain, Russian Federation, Bulgaria, Latvia, Czechia, Poland, Estonia, Belgium, Lithuania, Slovakia, Ukraine
Cascadian Therapeutics Inc.

Completed

Phase I Trial of PX-478

Lymphoma | Advanced Solid Tumors

United States
Cascadian Therapeutics Inc.

Completed

A Trial of PX-12 in Patients With a Histologically or Cytologically Confirmed Diagnosis of Advanced or Metastatic Cancer

Metastatic Cancer | Advanced Cancer

United States
Cascadian Therapeutics Inc.

Completed

Phase 1 and 2 Study of PX-866 and Cetuximab

Incurable Metastatic Colorectal Carcinoma | Incurable Progressive, Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

United States, Canada

Clinical Trials Sponsored by Vaxxinity, Inc.

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