Search clinical trials for: Bile duct diseases

Total 376464 results

Cascade Pharmaceuticals, Inc

Completed

Study of [14C]CS0159 in China Healthy Subjects

Primary Biliary Cholangitis

China
Forma Therapeutics, Inc.

Completed

A Study of FT-2102 in Patients With Advanced Solid Tumors and Gliomas With an IDH1 Mutation

Cohort 1a and 1b: Glioma (Advanced Gliomas and Glioblastoma Multiforme) | Cohort 2a and 2b: Hepatobiliary Tumors (Hepatocellular Carcinoma, Bile Duct Carcinoma, Intrahepatic Cholangiocarcinoma, Other Hepatobiliary Carcinomas) | Cohort 3a and 3b: Chondrosarcoma | Cohort 4a and 4b: Intrahepatic... and other conditions

United States, Korea, Republic of, Australia, United Kingdom, Spain, France
University Hospital Plymouth NHS Trust
University of Plymouth

Completed

Recurrence After Whipple's (RAW) Study

Pancreatic Cancer | Surgery | Bile Duct Cancer | Pancreatic Ductal Adenocarcinoma | Survivorship | Cholangiocarcinoma, Extrahepatic | Cancer Recurrence | Recurrent Cancer | Pancreatic Ductal Carcinoma | Cholangiocarcinoma of the Extrahepatic Bile Duct | Ampullary Cancer | Cholangiocarcinoma Resectable | Cancer... and other conditions

Spain, United Kingdom, Australia, Austria, Italy, Mexico, Sudan, Pakistan
Kepler University Hospital

Completed

Intraoperative ERCP Versus Therapeutic Splitting in Cholecysto-, Choledocholithiasis

Cholelithiasis, Common Bile Duct

Austria
GlaxoSmithKline

Available

Linerixibat Compassionate Use for Cholestatic Pruritus Adult Patients With Primary Biliary Cholangitis (PBC)

Pruritus
Takeda

Active, not recruiting

A Study of TAK-625 for the Treatment of Alagille Syndrome (ALGS)

Alagille Syndrome (ALGS)

Japan
Takeda

Active, not recruiting

A Study of TAK-625 for the Treatment of Progressive Familial Intrahepatic Cholestasis (PFIC)

Progressive Familial Intrahepatic Cholestasis (PFIC)

Japan
Albireo

Completed

Efficacy and Safety of Odevixibat in Patients With Alagille Syndrome (ASSERT)

Alagille Syndrome

United States, United Kingdom, France, Germany, Canada, Netherlands, Italy, Malaysia, Belgium, Israel, New Zealand, Poland, Turkey
Shanghai General Hospital, Shanghai Jiao Tong University...

Completed

Study of Microbiota in Bile From Patients With Common Bile Duct Stone During ERCP

Microbial Colonization | Common Bile Duct Calculi | Cholangiopancreatography, Endoscopic Retrograde

China
Mayo Clinic

Active, not recruiting

"Answers in Hours" A Randomized Controlled Trial Using Microbiome Metagenomics for Bile Duct Cultures

Benign Pancreatic Neoplasm | Malignant Pancreatic Neoplasm

United States
Mirum Pharmaceuticals, Inc.

Completed

Open Label Study to Evaluate Efficacy and Long Term Safety of LUM001 (Maralixibat) in the Treatment of Cholestatic Liver Disease in Patients With Progressive Familial Intrahepatic Cholestasis (INDIGO)

Progressive Familial Intrahepatic Cholestasis (PFIC)

United States, United Kingdom, Poland, France
Hannover Medical School
German Research Foundation

Terminated

Biliary Interventions in Critically Ill Patients With Secondary Sclerosing Cholangitis (BISCIT) (BISCIT)

Secondary Sclerosing Cholangitis

Germany
Affiliated Hospital of Guangdong Medical University

Enrolling by invitation

Modified vs Conventional Blumgart Anastomosis of LPD for the Effects of Pancreatic Fistula of Periampullary Carcinoma

Bile Duct Cancer | Pancreas Cancer | Ampullary Cancer | Duodenum Cancer

China
Intercept Pharmaceuticals
Syneos Health; Global PBC Study Group; Target RWE; UK PBC Study Group

Withdrawn

A Real-World Data Study to Evaluate the Effectiveness of OCA on Hepatic Outcomes in PBC Patients (HEROES-PBC)

Primary Biliary Cholangitis

United States
University of Nebraska

Completed

Evaluation of Omegaven™ Parenteral Nutrition in Patients With Total Parenteral Nutrition (TPN)-Induced Cholestasis

Cholestasis | Parenteral Nutrition Associated Liver Disease PNALD

United States
Lahey Clinic

Completed

Angled-tip vs. Straight-tip Guidewire in Biliary Cannulation

Bile Duct Diseases

United States
Mirum Pharmaceuticals, Inc.
Children's Hospital Medical Center, Cincinnati

Completed

Compassionate Treatment of Patients With Inborn Errors of Bile Acid Metabolism With Cholic Acid

Cholestasis | Peroxisomal Disorders | Adrenoleukodystrophy | Zellweger Syndrome | Infantile Refsum's Disease

United States
CymaBay Therapeutics, Inc.

Completed

RESPONSE: Response to Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and an Inadequate Control to or an Intolerance to Ursodeoxycholic Acid (UDCA)

Primary Biliary Cholangitis

United States, Spain, France, Korea, Republic of, Denmark, Australia, Italy, United Kingdom, Belgium, Canada, Russian Federation, Romania, Germany, Hungary, Mexico, Turkey, Argentina, Austria, Chile, Czechia, Greece, Israel, New Zealand and more
ChemomAb Ltd.

Completed

Subcutaneous Doses of CM-101 as a Treatment for Medical Conditions Involving Inflammatory and Fibrotic Mechanisms in Healthy Male Subjects

Nonalcoholic Steatohepatitis (NASH) | Primary Sclerosing Cholangitis (PSC) | Systemic Sclerosis (SSc)

Israel
PCI Biotech AS

Terminated

PCI Treatment/Gemcitabine & Chemotherapy vs Chemotherapy Alone in Patients With Inoperable Extrahepatic Bile Duct Cancer (RELEASE)

Cholangiocarcinoma

United States, Spain, Belgium, Germany, Italy, Denmark, Finland, France, Korea, Republic of, Norway, Poland, Sweden, Taiwan, Ukraine
Yale University
American Liver Foundation

Suspended

Mindfulness - Based Intervention in the Treatment of Fatigue in Patients With Primary Biliary Cholangitis

Primary Biliary Cholangitis

United States
Nottingham University Hospitals NHS Trust

Completed

Single Use ERCP Performance -SURE Study (SURE)

Cholangitis | Infection | ERCP

United Kingdom
Nottingham University Hospitals NHS Trust

Completed

Archimedes Bio-degradable Bile Duct Stent Study (ABBS)

Bile Leak | Common Bile Duct Stone With Chronic Cholecystitis

United Kingdom
Qassim University

Active, not recruiting

Mallampati Score for Prediction and Prognosis of Postoperative Mortality and Morbidity and Safety Profiles of Patients Undergoing Laparoscopic Cholecystectomy in Qassim Region

Cholecystitis | Difficult Intubation | Patient Satisfaction | Cholestasis | Mallampati Score

Saudi Arabia
Chinese University of Hong Kong

Completed

Safety and Tumoricidal Effect of Low Dose Foscan PDT in Patients With Inoperable Bile Duct Cancers (PDT)

Cholangiocarcinoma | Klatskin Tumor | Tumor

Hong Kong
National Cancer Institute (NCI)

Terminated

Combination of Trametinib (MEK Inhibitor) and Hydroxychloroquine (HCQ) (Autophagy Inhibitor) in Patients With KRAS Mutation Refractory Bile Tract Carcinoma (BTC).

Cholangiocarcinoma | Bile Duct Cancer | Biliary Tract Neoplasms | Biliary Cancer

United States
Children's Hospital of Fudan University

Completed

A Peer Support Network System Construction for the Primary Caregivers of Children With Biliary Atresia

Biliary Atresia Congenital Type 3

China
Mayo Clinic
National Comprehensive Cancer Network

Completed

Trifluridine/Tipiracil and Irinotecan for the Treatment of Advanced Refractory Biliary Tract Cancer

Stage III Gallbladder Cancer AJCC v8 | Stage IIIA Gallbladder Cancer AJCC v8 | Stage IIIB Gallbladder Cancer AJCC v8 | Refractory Gallbladder Carcinoma | Stage IV Gallbladder Cancer AJCC v8 | Stage IV Distal Bile Duct Cancer AJCC v8 | Stage IV Intrahepatic Bile Duct Cancer AJCC v8 | Stage IVB Gallbladder... and other conditions

United States
Elevation Oncology

Active, not recruiting

Study of Seribantumab in Adult Patients With NRG1 Gene Fusion Positive Advanced Solid Tumors

Sarcoma | Kidney Cancer | Breast Cancer | Head and Neck Cancer | Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Lung Cancer | Prostate Cancer | Cholangiocarcinoma | Bile Duct Cancer | Bladder Cancer | Metastatic Solid Tumor | Gallbladder Cancer | Uterine Cancer | Locally Advanced Solid Tumor

United States, Korea, Republic of, Australia, Canada
NCIC Clinical Trials Group

Terminated

Gemcitabine With/Out Capecitabine in Locally Advanced, Unresectable, or Metastatic Biliary Cancer

Liver Cancer | Gallbladder Cancer | Extrahepatic Bile Duct Cancer

Canada
Klus Pharma Inc.

Completed

Study of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 Gene

Cervical Cancer | Head and Neck Cancer | Mucoepidermoid Carcinoma | Pancreatic Cancer | Recurrent Prostate Cancer | Lung Cancer | Rectal Cancer | Solid Tumor | Prostate Cancer | Cholangiocarcinoma | Bile Duct Cancer | Recurrent Ovarian Carcinoma | Bladder Cancer | Skin Cancer | HER2-positive Breast Cancer | Rare Diseases | Colo-rectal Cancer and other conditions

United States
AdventHealth
University of Alabama at Birmingham

Completed

Comparison of On-Site Versus Off-Site Evaluation of Cholangioscopy-Guided Biopsies of the Bile Duct

Bile Duct Stricture

United States
Gilead Sciences

Terminated

Safety and Tolerability of Cilofexor in Participants With Primary Sclerosing Cholangitis (PSC) and Compensated Cirrhosis

Primary Sclerosing Cholangitis | Compensated Cirrhosis

United States
CuromeBiosciences

Completed

Evaluation of the Safety and Efficacy of HK-660S in Patients With Primary Sclerosing Cholangitis

Primary Sclerosing Cholangitis

Korea, Republic of
Michael J Cavnar, MD

Terminated

Codman Catheter/Synchromed Pump Hepatic Artery Chemotherapy for Unresectable Colorectal Metastases/Intrahepatic Cholangiocarcinoma

Colorectal Neoplasms | Bile Duct Neoplasms

United States
Imperial College London

Completed

The Metabolic Profile in Intrahepatic Cholestasis of Pregnancy and Diabetes Mellitus

Gestational Diabetes Mellitus | Intrahepatic Cholestasis of Pregnancy

United Kingdom
AdventHealth

Completed

Treatment Outcomes in Bile Duct Stones

Bile Duct Diseases | Gallstone | Bile Duct Obstruction

United States
University of Pittsburgh

Suspended

Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study (GREAT1)

Multiple Sclerosis | Diabetes Mellitus | Chronic Kidney Diseases | Gastritis | Rheumatoid Arthritis | Chronic Pain | Irritable Bowel Syndrome | Hepatitis | Inflammatory Bowel Diseases | Dyslipidemias | Chronic Disease | Celiac Disease | Cholecystitis | Crohn Disease | Cystic Fibrosis | Chronic Pancreatitis | NASH - Nonalcoholic... and other conditions

United States
Seoul National University Hospital

Completed

ETGBD in Surgically Unfit Patients With Both Choledocholithiasis and Cholecystolithiasis (ETGBD)

Efficacy

Korea, Republic of
Cara Therapeutics, Inc.

Terminated

Study to Evaluate the Safety and Efficacy of Oral CR845 (Difelikefalin) in Patients With Primary Biliary Cholangitis (PBC) and Moderate-to-Severe Pruritus

Cholestatic Pruritus

United States
Aswan University Hospital

Completed

Outcome of Kasai Portoenterostomy in Biliary Atresia in Upper Egypt

Biliary Atresia

Egypt
Sarah Magdy Abdelmohsen

Completed

Biliary Atresia With Rare Associations, a Case Report (BA)

BA - Biliary Atresia

Egypt
Institut Paoli-Calmettes

Completed

Prospective Evaluation of the Ablation Therapy With Bipolar Radio Frequency for Nonresectable Bile Duct Cancer (RFA-BILIAIRE)

Nonresectable Bile Duct Cancer

France
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Ramucirumab in Treating Patients With Advanced or Metastatic, Previously Treated Biliary Cancers That Cannot Be Removed by Surgery

Cholangiocarcinoma | Liver and Intrahepatic Bile Duct Carcinoma | Unresectable Gallbladder Carcinoma | Stage III Gallbladder Cancer AJCC v7 | Stage IIIA Gallbladder Cancer AJCC v7 | Stage IIIB Gallbladder Cancer AJCC v7 | Stage IV Gallbladder Cancer AJCC v7 | Stage IVA Gallbladder Cancer AJCC v7 | Stage... and other conditions

United States
AIO-Studien-gGmbH
Servier; Institut für Klinisch-Onkologische Forschung der Krankenhaus Nordwest...

Active, not recruiting

Nal-IRI With 5-fluorouracil (5-FU) and Leucovorin or Gemcitabine Plus Cisplatin in Advanced Biliary-tract Cancer (NIFE)

Biliary Tract Cancer | Extrahepatic Bile Duct Carcinoma | Non-Resectable Hepatocellular Carcinoma | Adenocarcinoma Metastatic | Adenocarcinoma of the Biliary Tract | Adenocarinoma Locally Advanced | Intrahepatic Bile Duct Carcinoma

Germany
South Valley University

Completed

ERCP Plus Laparoscopic Cholecystectomy Versus Laparoscopic Common Bile Duct Exploration and Cholecystectomy

Common Bile Duct Calculi

Egypt
Escient Pharmaceuticals, Inc
Novotech (Australia) Pty Limited

Completed

Evaluate the Safety, Tolerability, and PK of EP547 in Healthy Subjects and Subjects With Cholestatic or Uremic Pruritus

Pruritus | Cholestasis | Kidney Failure

Australia, New Zealand
Air Force Military Medical University, China

Completed

Effect of Endoscopic Papillary Large Balloon Dilation on Recurrent Rate of Patients With Recurrentstones in Bile Duct

Endoscopic Papillary Large Balloon Dilation

China
Advanced Endoscopy Research, Robert Wood Johnson...

Enrolling by invitation

Therapeutic Endoscopic Ultrasound for Gastrointestinal Disorders: A Multicenter Registry Study (TEUS Registry)

Gastrointestinal Dysfunction | Bile Duct Diseases | Gastrointestinal Cancer | Gastrointestinal Disease | Pancreatic Disease | Gastrointestinal Infection | Gastrointestinal Fistula | Gastro-Intestinal Disorder | Gastrointestinal Injury | Therapeutic Endoscopic Ultrasound | Advanced Endoscopy | Therapeutic Endoscopy and other conditions

United States
Beijing Friendship Hospital
Beijing YouAn Hospital; Beijing Ditan Hospital; The Affiliated Nanjing Drum Tower... and other collaborators

Active, not recruiting

PSC Clinical Epidemiology in China

Primary Sclerosing Cholangitis

China

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