Search clinical trials for: Cytochrome p450 CYP2C19 (Human)

Total 26269 results

University Hospital, Geneva

Recruiting

Risk of CYP2C19 Phenoconversion in Healthy Volunteers With Rapid, Normal, and Intermediate Predicted Metabolizers' Status (Switch19)

Healthy

Switzerland
Hamamatsu University
Yokoyama Foundation for Clinical Pharmacology

Unknown

Tailored Treatment of H. Pylori Infection Based Polymorphisms of CYP2C19 and 23S rRNA of H. Pylori

Gastritis | Helicobacter Infections | Gastric Ulcer | Duodenal Ulcer

Japan
Fundacion Infant

Completed

Role of Human Milk Bank in the Protection of Severe Respiratory Disease in Very Low Birth Weight Premature Infants

Respiratory Infections

Argentina
Federal University of São Paulo

Unknown

Comparison Amongst Scleral, Corneal and Amniotic Membrane Grafts to Restore Scleral Thinning

Scleral Thinning
Amgen

Completed

A First-in-human Study Evaluating Romosozumab (AMG 785) in Healthy Men and Postmenopausal Women

Osteopenia
Amgen

Completed

A First-in-human Study Evaluating AMG 167 in Healthy Men and Postmenopausal Women

Osteopenia
University of Maryland, Baltimore

Completed

A Study to Evaluate of the Efficacy of Enfuvirtide During the Induction Phase of Therapy

HIV Infections

United States
Regenstrief Institute, Inc.
Merck Sharp & Dohme LLC

Completed

Use of a Patient Education/Messaging Platform to Increase Uptake and Series Completion of the HPV Vaccine

Cervical Cancer | Human Papilloma Virus Infection Type 11 | Human Papilloma Virus Infection Type 16 | Human Papilloma Virus Infection Type 18 | Human Papilloma Virus Infection Type 6

United States
University of Miami
Integra LifeSciences Corporation

Recruiting

Human Amnion Membrane Allograft and Early Return of Erectile Function After Radical Prostatectomy (HAMMER)

Prostate Cancer | Erectile Dysfunction Following Radical Prostatectomy

United States
University of Florida
Scott R. MacKenzie Foundation

Completed

Prasugrel Versus Ticagrelor in Patients With CYP2C19 Loss-of-function: a Validation Study

Coronary Artery Disease

United States
Dong-A University

Completed

PRAsugrel or clopIdogrel In Acute Coronary SyndromE With CYP2C19 GENEtic Variants (PRAISE-GENE)

Acute Coronary Syndromes

Korea, Republic of
National Taiwan University Hospital
Department of Health, Executive Yuan, R.O.C. (Taiwan)

Unknown

Chinese Herb Nephropathy Epidemiology and Association With CYP2D6, CYP2C19, PXR, or MDR1 Polymorphism

Kidney Diseases

Taiwan
University of Southern California

Active, not recruiting

Implementing Precision Medicine Approaches to Guide Anti-platelet Selection

NSTEMI - Non-ST Segment Elevation MI | Acute Coronary Syndrome (ACS) | STEMI - ST Elevation Myocardial Infarction (MI) | Unstable Angina (UA)

United States
University of Calgary

Not yet recruiting

Source of Human Milk Fortifier and Intestinal Oxygenation in Preterm Infants <30 Weeks Gestation

Feeding; Difficult, Newborn
Bristol-Myers Squibb

Completed

Study to Characterize the Effects of Cytochrome p450 1A2 Inhibition on Systemic Exposure to BMS-986165

Healthy

United States
Fujian Maternity and Child Health Hospital

Recruiting

A Multicenter Cohort Study Assessing the Efficacy and Adverse Effects of HPV Vaccination in Chinese Women

Efficacy, Self | Adverse Effect | Woman | Human Papillomavirus Vaccines | China

China
Mutual Pharmaceutical Company, Inc.

Completed

Drug - Drug Interaction Study of Quinine Sulfate and Ciprofloxacin

Healthy
CSL Behring

Withdrawn

Fibrinogen Concentrate (Human) - Efficacy and Safety Study

Afibrinogenemia | Hypofibrinogenemia | Fibrinogen Deficiency
Janssen Research & Development, LLC

Completed

Interaction Study of Ibrutinib and Cytochrome P450 (CYP) 3A Inhibitors in Participants With B-cell Malignancy

B-Cell Chronic Lymphocytic Leukemia

Spain, Russian Federation, Canada
Bristol-Myers Squibb

Completed

Drug Interaction Study With Atazanavir Administered With and Without Ritonavir and a Cytochrome P450 Substrate Rosiglitazone

HIV Infections

United States
Chinese Academy of Sciences
LanZhou University

Completed

Cytochrome P450 2C19 Variant is Related to Pharmacokinetics of Glipizide Extended Release Tablet in Chinese Subjects

Pharmacokinetic | Genotype

China
The University of Hong Kong

Completed

Genotype Guided Versus Conventional Approach in Selection of Oral P2Y12 Receptor Blocker in Chinese Patients Suffering From Acute Coronary Syndrome

Acute Coronary Syndrome

Hong Kong
Vivaltis
CEISO; Human Physio

Not yet recruiting

Performance and Safety of the PHENIX LIBERTY, a Medical Device for Electrostimulation and Biofeedback, in the Treatment of Musculoskeletal Disorders

Musculoskeletal Disorder

France
Maastricht University Medical Center
Diabetes Fonds

Completed

In and ex Vivo Mitochondrial Function of the Heart (31P)

Diabetes Mellitus, Type 2 | Diabetic Cardiomyopathies

Netherlands
Hospital General Universitario Elche

Completed

Reduction of Postoperative Pain After Milligan-Morgan Haemorrhoidectomy With Application of Vitamin E Ointment

Pain
Jiangsu Gensciences lnc.

Completed

A Study to Evaluate the Pharmacokinetics，Safety and Tolerability of PEG Recombinant Human Coagulation Factor VIII-Fc Fusion Protein for Injection

Severe Hemophilia A

China
Bial - Portela C S.A.

Completed

Steady-state Pharmacokinetics of BIA 2-093 and Oxcarbazepine in Healthy Volunteers

Epilepsy

Portugal
University of Yalova

Completed

The Effect Of Therapeutic Touch To Mothers With Preterm Babies

Therapeutic Touch
Corcept Therapeutics

Completed

Study to Evaluate the Effects of a Cytochrome P450 2C19 Inhibitor on the Pharmacokinetics of Miricorilant

Non-alcoholic Steatohepatitis (NASH) | Antipsychotic Induced Weight Gain

United States
Hoffmann-La Roche

Completed

A Study to Evaluate the Effect of a Potent Cytochrome P450 (CYP) 3A Inhibitor on Ipatasertib

Healthy Volunteers

United States
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Treating Patients With Advanced or Recurrent Cancer

Cervical Cancer | Head and Neck Cancer | Esophageal Cancer | Vulvar Cancer | Anal Cancer | Penile Cancer

United States
Janssen R&D Ireland

Completed

A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Etravirine Administered in Combination With Other Antiretroviral Agents in Antiretroviral Treatment-Experienced HIV-1 Infected Patients

Human Immunodeficiency Virus (HIV) Infection

France, Ukraine, United States, Mexico, Romania, South Africa, Peru, Argentina, Puerto Rico, Russian Federation, Guatemala
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Tislelizumab in Combination With Anlotinib With ES-SCLC as Maintenance Therapy After First Line Chemotherapy

Small Cell Lung Carcinoma

China
Drugs for Neglected Diseases
World Health Organization; Swiss Tropical & Public Health Institute; Epicentre; Medecins Sans Frontieres, Netherlands and other collaborators

Completed

Efficacy - Safety of Eflornithine-Nifurtimox Combination Versus Eflornithine to Treat Human African Trypanosomiasis

Trypanosomiasis, African

Congo, The Democratic Republic of the, Congo
Merck Sharp & Dohme LLC

Completed

V501 Efficacy Study in Women Aged 18 to 26 (V501-027)

HPV Infections
Rikke Sorensen

Recruiting

Reduced Antithrombotic Strategy for High Bleeding Risk Patients With Myocardial Infarction (Dan-DAPT)

Myocardial Infarction

Denmark
Shanghai iCELL Biotechnology Co., Ltd, Shanghai...

Not yet recruiting

Safety and Efficacy Study of hAESCs Therapy for aGVHD (aGVHD，hAESCs)

GVHD,Acute
National Institute of Neurological Disorders and...

Completed

Gene Therapy for Gaucher's and Fabry Disease Using Viruses and Blood-Forming Cells

Gaucher's Disease

United States
University of Aarhus

Completed

Pharmacokinetics of Ghrelin

Healthy Subjects

Denmark
Protalix

Completed

Phase I Single Dose-Escalation Safety Study of Human Glucocerebrosidase (prGCD)

Gaucher Disease
German Institute of Human Nutrition

Unknown

Effects of Short-term Interventions for a Healthy Lifestyle on the Human Lipidome in Subjects With Metabolic Syndrome (GesundLeben)

Hypertension | Obesity | Metabolic Syndrome | NAFLD

Germany
University of California, Los Angeles

Completed

Effects of Xylooligosarcharide on Composition of the Human Colonic Microflora (XOS)

Healthy Volunteers | Bifidobacteria

United States
Kumamoto University

Completed

CYP2C19 Gene Alteration and Thienopyridine Resistance in Percutaneous Coronary Intervention Study (CALDERA-PCI)

Stable Angina

Japan
Qingdao Central Hospital

Completed

Radiotherapy Alternates Human Epidermal Growth Factor 2 (Her2) Expression in Human Breast Cancer

Human Epidermal Growth Factor 2 Negative Carcinoma of Breast

China
Biocad

Completed

A Safety and Efficacy Study of BCD-022 With Paclitaxel Compared to Herceptin With Paclitaxel in HER2+ Metastatic Breast Cancer Patients

Human Epithelial Receptor (HER)-2 Positive Breast Cancer

Ukraine, Russian Federation, Belarus, India
Jiangsu vcare pharmaceutical technology co., LTD

Completed

PK/PD Study of Vicagrel and Clopidogrel in Healthy Subjects With Different CYP2C19 Metabolizers

Acute Coronary Syndrome

United States, China
The Catholic University of Korea

Unknown

Therapeutic Drug Monitoring (TDM) of Voriconazole and Correlation With CYP2C19 Genotype in Korean Populations

Mycoses | Neutropenia | Bone Marrow Transplantation

Korea, Republic of
Institute of Tropical Medicine, Belgium
Sciensano; Military Hospital, Brussels

Completed

Simplifying the Rabies Pre-exposure Vaccination

Rabies

Belgium
Celularity Incorporated

Terminated

Safety of Intravenous Infusion of Human Placenta-Derived Cells (PDA001) for the Treatment of Adults With Stage II or III Pulmonary Sarcoidosis

Stage 2 Pulmonary Sarcoidosis | Stage 3 Pulmonary Sarcoidosis

United States
Istituto Scientifico Romagnolo per lo Studio e...

Completed

Myocet + Cyclophosphamide + Metformin Vs Myocet + Cyclophosphamide in 1st Line Treatment of HER2 Neg. Metastatic Breast Cancer Patients (MYME)

Human Epidermal Growth Factor 2 Negative Carcinoma of Breast

Italy

Search clinical trials for: Cytochrome p450 CYP2C19 (Human)

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