Search clinical trials for: HIV antiretroviral therapy lipid metabolism

Total 91435 results

City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Genetically Engineered Lymphocyte Therapy After Peripheral Blood Stem Cell Transplant in Treating Patients With High-Risk, Intermediate-Grade, B-cell Non-Hodgkin Lymphoma

Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Recurrent Non-Hodgkin Lymphoma

United States
University of Alberta
Merck Sharp & Dohme LLC

Completed

Combination Antiretroviral Therapy (cART) for PBC

Primary Biliary Cholangitis

Canada
ViiV Healthcare
GlaxoSmithKline; Janssen Pharmaceuticals

Active, not recruiting

Study to Evaluate the Efficacy, Safety, and Tolerability of Long-acting Intramuscular Cabotegravir and Rilpivirine for Maintenance of Virologic Suppression Following Switch From an Integrase Inhibitor in HIV-1 Infected Therapy Naive Participants

HIV Infections

United States, Germany, Netherlands, Spain, France, Canada, United Kingdom, Italy, South Africa, Russian Federation, Japan
H. Lee Moffitt Cancer Center and Research Institute
Bristol-Myers Squibb; Iovance Biotherapeutics, Inc.

Active, not recruiting

Ipilimumab With Lymphodepletion Plus Adoptive Cell Transfer and High Dose IL-2 in Melanoma Mets Pts

Metastatic Melanoma

United States
Jordan Collaborating Cardiology Group

Terminated

Tracking of Lipid Lowering Therapy in Jordan (JoLLA)

Dyslipidemias | Atherosclerotic Cardiovascular Disease

Jordan
Columbia University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Swiss... and other collaborators

Completed

Prebiotic GOS and Lactoferrin With Iron Supplements

Iron-deficiency

Kenya, Switzerland
FHI 360
University of Cape Town; City University of New York, School of Public Health

Completed

Comparison of Two Intrauterine Devices (IUDs) Among Cape Town HIV-positive Women

HIV

South Africa
Franck Boccara
Institut National de la Santé Et de la Recherche Médicale, France; Amgen; National...

Completed

COPANA - A09 PCSK 9 Substudy: Impact of Protease Inhibitors on PCSK9 Levels in Naive HIV-Infected Patients (COPANA)

Dyslipidemias | HIV Seropositivity | PCSK9

France
AVROBIO

Terminated

Lentiviral Vector Gene Therapy - The Guard1 Trial of AVR-RD-02 for Subjects With Type 1 Gaucher Disease

Gaucher Disease

United States, Canada
Orchard Therapeutics
Ospedale San Raffaele

Active, not recruiting

OTL-200 in Patients With Late Juvenile Metachromatic Leukodystrophy (MLD)

Lysosomal Storage Diseases | Metachromatic Leukodystrophy

Italy
Takeda

Active, not recruiting

A Study Measuring Substances Potentially Indicating Bone Problems in Adults With Type 1 Gaucher Condition

Gaucher Disease

Spain
St. Jude Children's Research Hospital
Cookies for Kids' Cancer; CURE Childhood Cancer, Inc.

Active, not recruiting

Therapy for Children With Advanced Stage Neuroblastoma

Neuroblastoma

United States
National Cancer Institute (NCI)

Active, not recruiting

Assessment of Bone Mineral Density in People Living With HIV and KSHV Associated Malignancies: A Retrospective Longitudinal Analysis

Kaposi Sarcoma | Primary Effusion Lymphoma | KSHV Associated Multicentric Castleman Disease | IL-6 Related KSHV Associated Cytokine Syndrome

United States
Takeda

Withdrawn

A Study to Learn About Metachromatic Leukodystrophy (MLD) in Children in Spain (mECHromatic)

Metachromatic Leukodystrophy (MLD)

Spain
VA Office of Research and Development
Corporal Michael J. Crescenz VA Medical Center; VA Boston Healthcare System; Ralph...

Completed

Unmet Social Needs Study

Hypertension | Cardiovascular Disease | Diabetes Mellitus | Hyperlipidemia

United States
Ensoma

Completed

Study Assessing Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MGTA-145 in Healthy Volunteers as a Single Agent or in Combination With Plerixafor

Healthy Volunteers

United States
National Institute of Allergy and Infectious Diseases...
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Anti-inflammatory Effects of Letermovir (Prevymis) in Adults With Human Immunodeficiency Virus (HIV)-1 and Asymptomatic Cytomegalovirus (CMV) Who Are on Suppressive Antiretroviral Therapy, Plus Its Effect on Chronic Inflammation, HIV Persistence and Other Clinical Outcomes. (ELICIT)

HIV Infections | Cytomegalovirus | CMV

United States
Ensoma
National Marrow Donor Program

Terminated

MGTA-145 + Plerixafor in the Mobilization of HSCs for Allogeneic Transplant in Hematologic Malignancies

Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome | Acute Myelogenous Leukemia | Healthy Donors | Related Donors Donating PBSC to a Family Member

United States
National Institute of Neurological Disorders and...

Completed

HERV-K Suppression Using Antiretroviral Therapy in Volunteers With Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis

United States
University of California, San Francisco
National Institute of Allergy and Infectious Diseases (NIAID); Makerere University and other collaborators

Completed

Simplified Isoniazid Preventive Therapy Strategy to Reduce TB Burden (SEARCH-IPT)

HIV/AIDS | Tuberculosis

Uganda
Harvard School of Public Health (HSPH)
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

An Intervention to Improve Antenatal Access to CD4 Testing and HAART in Botswana

HIV Infection | Pregnancy

Botswana
AVROBIO

Terminated

Open Label, Study Of Efficacy and Safety Of AVR-RD-01 for Treatment-Naive Subjects With Classic Fabry Disease

Fabry Disease

United States, Australia, Brazil
Norwegian University of Science and Technology

Completed

Effective Endurance Training in Metabolic Syndrome

Hypertension | Overweight | Dyslipidemia | Impaired Glucose Tolerance

Norway
University of Maryland, College Park
Canadian Institutes of Health Research (CIHR); University of Washington; Swiss... and other collaborators

Completed

Pilot Test of a Couple-Based Medication Adherence Intervention for HIV-Positive Women and Their Male Partners in South Africa

Human Immunodeficiency Virus

South Africa
Shanghai Public Health Clinical Center
Yunnan AIDS Care Center; Xixi Hospital of Hangzhou

Active, not recruiting

Switching From TDF-based Antiretroviral Therapy Regimens to B/F/TAF in Virally Suppressed Adults With HIV-1 Infection

HIV-1-infection

China
Takeda

Completed

A Study of Enzyme Replacement Therapy (VPRIV) in People With Type 1 Gaucher Disease Who Were Previously Treated With Substrate Reduction Therapy (SWITCH)

Gaucher Disease

United States
University of Melbourne
Melbourne Health; National Health and Medical Research Council, Australia; University... and other collaborators

Active, not recruiting

Towards a Functional Cure for HBV - The COMMIT Cohort Study (COMMIT)

Hiv | HBV Coinfection

India, Malaysia, Thailand
Boston University
Bill and Melinda Gates Foundation; University of Witwatersrand, South Africa

Active, not recruiting

Survey of Procedures and Resources for Initiating Treatment of HIV in Africa-South Africa (SPRINT-SA)

HIV | Antiretroviral Therapy

South Africa
Boston University
Bill and Melinda Gates Foundation; University of Witwatersrand, South Africa; Clinton Health Access Initiative Inc...

Active, not recruiting

Survey of Procedures and Resources for Initiating Treatment of HIV in Africa-Zambia (SPRINT-Zambia)

HIV | Antiretroviral Therapy

South Africa, Zambia
Boston University
Bill and Melinda Gates Foundation; University of Witwatersrand, South Africa; Clinton Health Access Initiative Inc...

Active, not recruiting

Survey of Procedures and Resources for Initiating Treatment of HIV in Africa-Malawi (SPRINT-Malawi)

HIV | Antiretroviral Therapy

Malawi, South Africa
Walter Reed Army Institute of Research (WRAIR)
US Military HIV Research Program; Kenya Medical Research Institute

Completed

Clinic-based ART Diagnostic Evaluation (CLADE)

Acquired Immunodeficiency Syndrome | HIV Infection | RNA Virus Infections | Virus Diseases

Kenya
University of Nove de Julho

Completed

Combination of Light and Ultrasound to Reduce Abdominal Fat

Subcutaneous Fat Disorder

Brazil
LIB Therapeutics LLC
Medpace, Inc.

Completed

Study to Assess the Efficacy and Safety of LIB003 in HeFH Patients on Oral Lipid Therapy Needing Further LDL-C Reduction (LIBerate-FH)

Heterozygous Familial Hypercholesterolemia

United States, Israel, Norway, South Africa, Turkey
Janssen-Cilag Farmaceutica Ltda.

Completed

A Study to Evaluate Virologic Response in Participants Newly Diagnosed With HIV-1

HIV

Portugal
Jonsson Comprehensive Cancer Center

Active, not recruiting

Gene and Vaccine Therapy in Treating Patients With Advanced Malignancies

Malignant Neoplasm

United States
Freeline Therapeutics

Completed

A Long Term Follow-Up Study of Fabry Disease Subjects Treated With FLT190

Lysosomal Storage Diseases | Fabry Disease

Germany, United Kingdom
Xinqiao Hospital of Chongqing
University of Messina; Azienda Ospedaliera Universitaria Policlinico "G. Martino...

Completed

The Effect of GLP-1 Agonists Versus OCs on Reproductive Disorders and Cardiovascular Risks in Overweight PCOS

Obesity | Overweight | Polycystic Ovary Syndrome (PCOS)

China
National Institutes of Health Clinical Center (CC)

Completed

Impact of Steady State Cobicistat and Darunavir/Cobicistat on the Pharmacokinetics and Pharmacodynamics of Oral Anticoagulants (Rivaroxaban, Apixaban) in Health Volunteers

Healthy Volunteers

United States
REGENXBIO Inc.

Active, not recruiting

A First-in-Human Study in Pediatric Patients With Ocular CLN2 Disease

Neuronal Ceroid Lipofuscinosis Type 2

United Kingdom
University of Colorado, Denver
Gilead Sciences

Terminated

Rapid Start vs. Standard Start Antiretroviral Therapy (ART) in HIV (B-HASTE)

HIV/AIDS

United States
University of Cape Town
King's College London; University of KwaZulu

Completed

Collaborative Care for the Detection and Management of Depression Among Adults Receiving Antiretroviral Therapy in South Africa (COBALT)

Depression | HIV/AIDS | Chronic Diseases of Lifestyle

South Africa
University of California, San Francisco
Texas A&M University; ViiV Healthcare; Auburn University; Nova Southeastern University

Completed

Preparing for Pharmacy-based Delivery of Long-acting Injectable Antiretroviral Therapy (LAI-ART)

Hiv

United States
Technical University of Munich

Completed

Dual Therapy With Boosted Darunavir + Dolutegravir (Dualis)

HIV-Infection

Germany
Orchard Therapeutics
Ospedale San Raffaele

Active, not recruiting

A Safety and Efficacy Study of Cryopreserved OTL-200 for Treatment of Metachromatic Leukodystrophy (MLD)

Lysosomal Storage Disease | Metachromatic Leukodystrophy

Italy
Stanford University
Gilead Sciences

Completed

Treatment Outcomes in Chronic Hepatitis B Patients on Sequential Therapy With Tenofovir Alafenamide (TAF)

Hepatitis B, Chronic

United States, Taiwan, Japan, Korea, Republic of
Royal United Hospitals Bath NHS Foundation Trust
University of Oxford; University of Bristol; University of Bath; National Institute... and other collaborators

Active, not recruiting

Super-Rehab: Can we Achieve Coronary Artery Disease Regression?

Coronary Artery Disease | Metabolic Syndrome

United Kingdom
Response Pharmaceuticals

Completed

Comparison of SLx-4090 Combined With Statin Therapy Versus Statin Alone in Reducing LDL-C in Patients With Hyperlipidemia

Hyperlipidemia

United States
Merck Sharp & Dohme LLC

Active, not recruiting

A Switch to Doravirine/Islatravir (DOR/ISL) in Participants With Human Immunodeficiency Virus Type 1 (HIV-1) Who Are Virologically Suppressed on Antiretroviral Therapy (ART) (MK-8591A-051)

HIV-1 Infection

United States, Australia, Canada, Colombia, Japan, South Africa, Switzerland, United Kingdom
RTI International
Kheth'Impilo

Completed

Implementation Research for Vulnerable Women in South Africa

HIV | Substance Abuse

United States, South Africa
ViiV Healthcare

Completed

'COMBINE-2': Real-world Evidence for Effectiveness of Two Drug Regimen, Antiretroviral Therapy With Integrase Inhibitors Plus a Reverse Transcriptase Inhibitor

HIV Infections

Spain

Search clinical trials for: HIV antiretroviral therapy lipid metabolism

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