Search clinical trials for: Hematopoietic stem cell transplantation (HSCT)

Total 63331 results

Instituto Nacional de Cancer, Brazil

Recruiting

Low Power Laser Therapy As Prevention Of Oral Mucositis And Oropharyngeal Pain In Patients Undergoing Allogenetic HSCT

Stomatitis | Hematopoietic Stem Cell Transplantation | Low-Level Light Therapy

Brazil
Nanfang Hospital of Southern Medical University
Guangxi Medical University; Peking University People's Hospital; Sun Yat-Sen... and other collaborators

Unknown

TKI Therapy Based on Molecular Monitoring in Allogeneic-HSCT Recipients With Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia

Stem Cell Transplantation | Minimal Residual Disease | Philadelphia Chromosome Positive Acute Lymphocytic Leukemia

China
National Institutes of Health Clinical Center (CC)
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effectiveness of a Stress Reduction Intervention in Caregivers of Allogeneic Hematopoietic Stem Cell Transplant (HSCT) Recipients

Stress, Psychological | Caregivers

United States
The First Affiliated Hospital of Soochow University

Not yet recruiting

Decitabine, Venetoclax and Blinatumomab for Maintenance Following HSCT in Patients With Ph-Negative B-ALL

B-cell Acute Lymphoblastic Leukemia

China
PETHEMA Foundation

Recruiting

Treatment of Breakpoint Cluster Region-Abelson (BCR-ABL) Negative ALL in Adults

Acute Lymphoblastic Leukemia

Spain
University Hospital Carl Gustav Carus
German Research Foundation

Terminated

Haematopoietic Stem Cell Transplantation (HSCT) in Comparison to Conventional Consolidation Therapy for Patients With Acute Myeloid Leukemia (AML) (Intermediate Risk) </= 60y. After First CR (AML)

Leukemia, Myeloid, Acute

Germany
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

Preservation and Transfer of HBV Immunity After Allogeneic HSCT for SCD (PROTECT)

Sickle Cell Disease

Netherlands
Gruppo Italiano Trapianto di Midollo Osseo
Azienda Policlinico Umberto I

Completed

Prospective Survey of CMV, Herpesviruses Infections and Diseases in Allo-HSCT (CYTOALLOSURVEY)

Hematologic Diseases | Stem Cell Transplant Complications | Cytomegalovirus Viremia | Herpesvirus Infection

Italy
Institute of Hematology & Blood Diseases Hospital

Not yet recruiting

Letermovir for Primary Prophylaxis of Cytomegalovirus Infection After R+HID-HSCT

The Incidence of Peripheral Blood CMV Activation and Confirmed Clinically Significant CMV Infection Within 24 Weeks After Transplantation
Randy Windreich

Completed

Reduced-Intensity Conditioning (RIC) and Myeloablative Conditioning (MAC) for HSCT in AML/MDS

Acute Myeloid Leukemia (AML) | Myelodysplastic Syndrome (MDS) | Hematopoietic Stem Cell Transplant (HSCT)

United States
M.D. Anderson Cancer Center
TAP Pharmaceutical Products Inc.

Completed

GnRH Analogue for Ovarian Function Preservation in Hematopoietic Stem Cell Transplantation Patients

Amenorrhea | Premature Ovarian Failure | Ovarian Function Insufficiency

United States
Hospital Universitario Dr. Jose E. Gonzalez

Recruiting

Evaluation of Safety & Efficacy for the Prevention of Ocular GVHD With Ophthalmic Tacrolimus vs Cyclosporine in Allo-HSCT

Ocular Graft-versus-host Disease

Mexico
Seres Therapeutics, Inc.
Memorial Sloan Kettering Cancer Center

Active, not recruiting

A Multiple Dose Study to Evaluate Safety, Tolerability, PK, and Efficacy of SER-155 in Adults Undergoing HSCT

Allogeneic Hematopoietic Stem Cell Transplantation

United States
Medical College of Wisconsin

Terminated

Hematopoietic Stem Cell Transplantation (HSCT) Using CD34 Selected Mismatched Related Donor and One Umbilical Cord Unit (Haplo/Cord)

Lymphoma, Non-Hodgkin | Lymphoma, Hodgkins | Leukemia, Lymphocytic, Acute | Leukemia, Myelocytic, Acute | Leukemia, Myeloid, Chronic | Leukemia, Lymphocytic, Chronic
The University of Hong Kong

Completed

Risk of Hepatitis B Reactivation After Bone Marrow Transplantation With Prior Hepatitis B Virus (HBV) Exposure

Exposure to Hepatitis B Virus

Hong Kong
The Korean Society of Pediatric Hematology Oncology

Completed

Study of Reduced Toxicity Myeloablative Conditioning Regimen for Wiskott-Aldrich Syndrome (WAS)

Wiskott-Aldrich Syndrome

Korea, Republic of
Zhongnan Hospital

Recruiting

An Open, Single Center, Randomized Controlled Clinical Study of UCB (Cord Blood) in the Treatment of Newly Diagnosed Acute Myeloid Leukemia (AML)

UCB (Cord Blood) Microtransplantation in the Treatment of Newly Diagnosed Acute Myeloid Leukemia (AML)

China
Masonic Cancer Center, University of Minnesota

Completed

Biochemical Correction of Severe EB by Allo HSCT and "Off-the-shelf" MSCs

Epidermolysis Bullosa

United States
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Active, not recruiting

Activated T Lymphocytes Expressing CARs, Relapsed CD19+ Malignancies Post-Allo HSCT(CARPASCIO) (CARPASCIO)

Non-Hodgkin's Lymphoma | B-Cell ALL | B-Cell CLL

United States
Wuhan Sian Medical Technology Co., Ltd
Wuhan Union Hospital, China; Xiangyang Central Hospital; Jingzhou Central Hospital and other collaborators

Unknown

Anti-CD19 CAR-T Therapy Bridging to HSCT for CD19+ B-Cell Malignancies

B Cell Lymphoma | Acute Lymphoblastic Leukemia

China
National Institute of Allergy and Infectious Diseases...

Completed

Safety, Reactogenicity and Immunogenicity of MVA in Hematopoietic Stem Cell Transplant (HSCT) Subjects

Variola Major (Smallpox)

United States
First Affiliated Hospital Xi'an Jiaotong University

Not yet recruiting

Efficacy and Safety of MTBF Conditioning Regimen for Salvageable Allo-HSCT in the Treatment of R/R AML

Refractory Acute Myeloid Leukemia | Conditioning | Hematopoietic Stem Cell Transplantation | Relapse Leukemia
The First Affiliated Hospital of Soochow University

Recruiting

TBI/Flu/Bu/Mel Combined With Secondary UCBT in Patients With Hematological Malignancies Who Relapsed After Allo-HSCT

Hematopoietic Stem Cell Transplantation | Relapse/Recurrence | Hematopoietic Malignancy

China
Nanfang Hospital of Southern Medical University
Peking University People's Hospital; Guangzhou First People's Hospital; Sun Yat-Sen... and other collaborators

Recruiting

G-CSF+DAC+BUCY vs G-CSF+DAC+BF Conditioning Regimen for High-risk MDS Undergoing Allo-HSCT

Myelodysplastic Syndrome | Allogeneic Hematopoietic Stem Cell Transplantation | Conditioning

China
Masonic Cancer Center, University of Minnesota

Recruiting

Allo HSCT Using RIC and PTCy for Hematological Diseases

Follicular Lymphoma | Myelodysplastic Syndromes | Leukemia, Myeloid | Myelofibrosis | Burkitt Lymphoma | Marginal Zone Lymphoma | Acute Lymphocytic Leukemia | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia | Prolymphocytic Leukemia | Plasma Cell Leukemia | Myeloproliferative Neoplasm | Small Lymphocytic... and other conditions

United States
Micah Skeens
National Institute of Nursing Research (NINR)

Recruiting

BMT4me: Post-HSCT Medication Adherence mHealth App (Bmt4me 2)

Adherence, Medication | Stem Cell Transplant | Digital Health

United States
Case Comprehensive Cancer Center

Completed

Hematopoietic Stem Cell Transplant for Sickle Cell Disease

Sickle Cell Disease | Sickle Cell Anemia | SCD

United States
Guangdong Ruishun Biotech Co., Ltd
Anhui Provincial Hospital

Recruiting

RC1012 Injection (Allo-DNT Cells) for the Prevention of Relapse in AML Patients After Allo-HSCT

Acute Myeloid Leukemia

China
University of British Columbia

Recruiting

Polyomic Biomarker Verification in Adult Chronic Graft-Versus-Host Disease (ABLE3.0/CTTC2201)

Leukemia | Allogeneic Hematopoietic Stem Cell Transplantation | Blood Cancer | Chronic Graft-versus-Host-Disease | Non-Malignant Hematologic and Lymphocytic Disorder

United States, Canada
M.D. Anderson Cancer Center
Celgene Corporation

Terminated

Lenalidomide (Revlimid®) as Second Line Therapy in Patients With Chronic Graft-Vs-Host Disease (GVHD)

Graft-versus-Host Disease

United States
Federal Research Institute of Pediatric Hematology...

Unknown

Plerixafor/G-CSF as Additional Agents for Conditioning Before HSCT in CGD Patients

Chronic Granulomatous Disease

Russian Federation
Massachusetts General Hospital
Novartis

Terminated

Phase I Trial of LDE225 for Steroid-refractory Chronic GVHD After Allogeneic HSCT

Graft Versus Host Disease

United States
Paul Szabolcs

Enrolling by invitation

Sequential Cadaveric Lung and Bone Marrow Transplant for Immune Deficiency Diseases (BOLT+BMT)

Chronic Granulomatous Disease (CGD) | Wiskott-Aldrich Syndrome | Severe Chronic Neutropenia | Severe Combined Immunodeficiency (SCID) | Immunodeficiency With Predominant T-cell Defect, Unspecified | Hyper IgE Syndromes | Hyper IgM Deficiencies | Mendelian Susceptibility to Mycobacterial Disease | Common...

United States
Nantes University Hospital

Completed

Allogeneic Stem Cell Transplant With Clofarabine, Busulfan and Antithymocyte Globulin (ATG) for Adult Patients With High-risk Acute Myeloid Leukemia/Myelodysplastic Syndromes (AML/MDS) or Acute Lymphoblastic Leukemia (ALL) (Cloric)

AML | MDS | ALL | BAL

France
Great Ormond Street Hospital for Children NHS Foundation...
Orchard Therapeutics

Completed

Lentiviral (LV) Gene Therapy for Adenosine Deaminase (ADA) Deficiency

Adenosine Deaminase Deficiency | Severe Combined Immunodeficiencies (SCID)

United Kingdom
National Institutes of Health Clinical Center (CC)

Recruiting

A Nature-Based Virtual Reality (VR) Intervention in Family Caregivers of Allogeneic Hematopoietic Stem Cell Transplant (HSCT) Recipients

Neoplasm | Caregivers

United States
Karen Ballen, MD

Recruiting

Study of Tagraxofusp for Post-Transplant Maintenance for Patients With CD 123+ AML, MF and CMML (HSCT 002)

Acute Myeloid Leukemia | Myelofibrosis | Chronic Myelomonocytic Leukemia

United States
Nanfang Hospital of Southern Medical University
Xiangya Hospital of Central South University; Peking University People's Hospital and other collaborators

Completed

Influence of Co-existing Mutations on Sorafenib Maintenance Therapy After Allo-HSCT for Patients With FLT3-ITD AML

Acute Myeloid Leukemia | Hematopoietic Stem Cell Transplantation | Acute Myeloid Leukemia With FLT3/ITD Mutation

China
Memorial Sloan Kettering Cancer Center

Terminated

T-cell Depleted Hematopoietic Stem Cell Boosts Without Conditioning for Poor Marrow Graft Function Following Allogeneic Hematopoietic Stem Cell Transplantation

Hematopoietic Stem Cell Transplant | Poor Marrow Graft Function

United States
Scripps Health

Completed

Unrelated Donor Stem Cell Transplantation

Myelodysplastic Syndromes | Multiple Myeloma | Hodgkin's Lymphoma | Non-Hodgkin's Lymphoma | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia | Small Lymphocytic Lymphoma | Paroxysmal Nocturnal Hemoglobinuria | Severe Aplastic Anemia | Myeloproliferative... and other conditions

United States
Novartis Pharmaceuticals

Active, not recruiting

Tisagenlecleucel in Adult Patients With Aggressive B-cell Non-Hodgkin Lymphoma (BELINDA)

Non-Hodgkin Lymphoma

Spain, Taiwan, Australia, Belgium, Germany, Italy, Singapore, Austria, France, Switzerland, Hong Kong, United States, Netherlands, Norway, United Kingdom, Brazil, China, Japan
Zhejiang University

Recruiting

Venetoclax and Decitabin Based Conditioning Regimen Followed With Post-HSCT Decitabin Maintenance Therapy in TP53 Mutant AML/MDS Patients

Hematopoietic Stem Cell Transplantation | TP53

China
Gruppo Italiano Trapianto di Midollo Osseo

Completed

Post Transplant High-Dose Cy as GvHD Prophylaxis in 1 HLA Mismatched Unrelated HSCT for Myeloid Malignancies (GITMO-PHYLOS)

Myeloid Malignancies

Italy
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Completed

Low Dose IL-2, Hematopoietic Stem Cell Transplantation, IL2 for GVHD (IL2 for GVHD)

Hodgkin Lymphoma | Acute Lymphoblastic Leukemia | Non-Hodgkin Lymphoma | AML | Myelodysplastic Syndrome | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia | Myeloproliferative Disorder | ALL | Non-malignant Diseases Requiring Allogeneic HSCT

United States
Nottingham University Hospitals NHS Trust
University of Nottingham; University of Sheffield; Sheffield Teaching Hospitals...

Completed

Nutrition and Metabolic Prehabilitation in HSCT Patients UK and ROI. BSBMT Multi-centre Survey.

Nutrition Aspect of Cancer | Stem Cell Transplant Complications | Prehabilitation | Haematological Malignancy | Nutritional and Metabolic Disease | Bone Marrow Transplant Complications | Exercise Interventions

United Kingdom
Wuhan Sian Medical Technology Co., Ltd
Wuhan Union Hospital, China; Xiangyang Central Hospital; Jingzhou Central Hospital and other collaborators

Unknown

Anti-CD19 CAR-T Therapy Combine With HSCT to Treat MRD+ B-cell Malignancies

B Cell Lymphoma | Acute Lymphoblastic Leukemia

China
National Research Center for Hematology, Russia

Unknown

Intraosseous Administration of Mesenchymal Stromal Cells for Patients With Graft Failure After Allo-HSCT

Mesenchymal Stem Cell Transplantation

Russian Federation
Nanfang Hospital of Southern Medical University
Peking University People's Hospital; Guangzhou First People's Hospital; Sun Yat-Sen... and other collaborators

Recruiting

G-CSF+DAC+BUCY vs G-CSF+DAC+BF Conditioning Regimen for Secondary Acute Myeloid Leukemia Undergoing Allo-HSCT

Allogeneic Hematopoietic Stem Cell Transplantation | Conditioning | Secondary Acute Myeloid Leukemia Evolving From MDS

China
Xiamen Amoytop Biotech Co., Ltd.
Shanghai Jiao Tong University Affiliated First People's Hospital

Completed

Antifugal Effect of Recombinant Human Granulocyte-macrophage Stimulating Factor (rhGM-CSF) in Patients Post Allo-HSCT

Mycoses

China
Lophius Biosciences GmbH
German Federal Ministry of Education and Research

Completed

Clinical Validation of Lophius Biosciences Kit T-Track® CMV in Allo-HSCT Recipients (AlloProtectCMV)

Cytomegalovirus Infection | GVHD

Germany

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