Search clinical trials for: Knee pain, osteoarthritis, non-surgical treatment, age 65

Total 200910 results

Hospices Civils de Lyon

Not yet recruiting

Hydroxychloroquine as a Steroid-sparing Agent in Extrapulmonary Sarcoidosis (CAESAR)

Sarcoidosis, Pulmonary

France
AbbVie

Recruiting

Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer (NSCLC), Head and Neck Squamous Cell Carcinoma (HNSCC) and Other Solid Tumors, Receiving Intravenous (IV) Infusion of ABBV-514 Alone or in Combination With Budigalimab

Non-Small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma

United States, Israel, Japan, Korea, Republic of
Alexion
Achillion, a wholly owned subsidiary of Alexion

Completed

Safety, Tolerability, and Antiviral Activity of ACH-0141625 or Placebo in Combination With Peginterferon and Ribavirin in Hepatitis C Virus (HCV) Positive Participants

Hepatitis C

United States, Belgium
CSL Behring

Completed

Phase IIB Dose Ranging Study in Subjects With Moderate to Severe Rheumatoid Arthritis

Rheumatoid Arthritis

Italy, United States, France, Argentina, Mexico, Japan, Canada, Hungary, South Africa
AbbVie

Completed

Study Comparing Veliparib Plus FOLFIRI Versus Placebo Plus FOLFIRI With or Without Bevacizumab in Previously Untreated Metastatic Colorectal Cancer

Untreated Metastatic Colorectal Cancer
Government Medical College, Haldwani

Completed

Comparison of Levobupivacaine, Ropivacaine and Bupivacaine in Epidural Anaesthesia

Pain Insensitivity, Congenital

India
Endocyte

Withdrawn

Safety and Efficacy Study of Vintafolide and Vintafolide Plus Paclitaxel Compared to Paclitaxel Alone in Participants With Triple Negative Breast Cancer (TNBC) (MK-8109-004)

Breast Neoplasms
Cedars-Sinai Medical Center

Active, not recruiting

Safety and Efficacy of Omission of Sentinel Node Biopsy in Patients With Estrogen-Positive Breast Cancer Over Age 65

Breast Cancer

United States
Svendborg Hospital
Odense University Hospital

Completed

Coronary Artery Plaque Burden in Asymptomatic Danish Men Aged 65-75 Years and the Relation to Glycemic Status. (DANCAP)

Coronary Artery Disease | Dysglycemia

Denmark
UNC Lineberger Comprehensive Cancer Center

Completed

Impact of Physical Activity on Biomarker of Aging and Body Composition Among Breast Cancer Survivors Age 65 and Older

Breast Cancer | Physical Activity | Aging

United States
Lund University Hospital
Mundipharma Pte Ltd.; Roche Pharma AG; Celgene

Completed

Lenalidomide, Bendamustine and Rituximab as First-line Therapy for Patients Over 65 Years With Mantle Cell Lymphoma. (LENA-BERIT)

Mantle Cell Lymphoma

Finland, Denmark, Norway, Sweden
InCor Heart Institute

Completed

Influence of Caloric Restriction and Resveratrol in the Sirtuin System in Women and Men Aged 55 to 65 Years

Lipid Metabolism Disorders | Vascular System Injuries | Endothelial Disfunction

Brazil
Istituto Nazionale di Ricovero e Cura per Anziani
Regione Marche

Unknown

Study on the Effects of Oxygen-ozone Therapy on Back Pain in Subjects Aged 65 or Older (O2-O3)

Back Pain

Italy
Abramson Cancer Center of the University of Pennsylvania

Completed

Single Nucleotide Polymorphism (SNP) Panels and Risk Assessment in Women Undergoing Mammography

Mammography

United States
Institut de Médecine et d'Epidémiologie Appliquée...
Pierre and Marie Curie University

Recruiting

Switch to TAF+FTC+BIC in HIV-1-infected Patients Over 65 Years Old at Risk of Polymedication (BICOLDER)

HIV Infections

France
University of California, Davis
Veloxis Pharmaceuticals

Completed

A Pilot Study to Evaluate Impact on Neurological Side Effects (Cognition, Memory, and Tremor) in Elderly (Age>65) Patients

Toxicity | Neurotoxicity | Kidney Transplant; Complications | Drug Toxicity

United States
Istituto Nazionale di Ricovero e Cura per Anziani

Enrolling by invitation

Epidemiological Observatory on the Health Conditions of Inpatients Aged 65 or Older at the INRCA Research Hospitals (report-AGE)

Aging | Inpatients

Italy
Centre Hospitalier Universitaire de Nīmes

Completed

Impact of Collaborative Pharmaceutical Care on Hospital Admission Drug Prescriptions for Patients 65 Years of Age and Older (MEDREV)

Aged | Hospitalization | Patient Admission

France
Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.
Air Force Military Medical University, China; Jiangsu Province Centers for... and other collaborators

Completed

Phase IIb Clinical Study of Recombinant Mycobacterium Tuberculosis Allergen ESAT6-CFP10 on Healthy People Aged 18-65 (IIb-healthy)

Tuberculosis

China
Memorial Sloan Kettering Cancer Center

Completed

Prospective Trial of Vaccine Responses Against Pneumococcus and Influenza in Adult Cancer Patients 65 Years of Age and Older

Breast Cancer | Lung Cancer | Prostate Cancer

United States
QLT Inc.

Completed

Oral QLT091001 in Retinitis Pigmentosa (RP) Subjects With an Autosomal Dominant Mutation in Retinal Pigment Epithelial 65 Protein (RPE65)

Retinitis Pigmentosa (RP)

Canada, Ireland
University of Kentucky
Cephalon

Withdrawn

Frontline Treatment With Bendamustine in Combination With Rituximab in Adults Age 65 or Older With Chronic Lymphocytic Leukemia (CLL)

Chronic Lymphocytic Leukemia

United States
University Hospital Freiburg
Ludwig-Maximilians - University of Munich; University Hospital Heidelberg; University... and other collaborators

Unknown

Methotrexate-based Chemo-immunotherapy Followed by Maintenance Therapy for Patients > 65 Years With Central Nervous System (CNS)-Lymphoma (PRIMAIN)

Primary Non Hodgkin Lymphoma of the Central Nervous System

Germany
University Hospital, Basel, Switzerland

Completed

Triage - Symptoms and Other Predictors in an All-comer Emergency Department Population (EMERGE VI)

Triage Risk Stratification

Switzerland
Hackensack Meridian Health

Terminated

Auto Transplant High Dose Melphalan vs High Dose Melphalan+Bortezomib in Pts With Multiple Myeloma Age 65 Years or Older

Multiple Myeloma

United States
Sanofi Pasteur, a Sanofi Company

Completed

A Study of the Safety and Immunogenicity of High-Dose Quadrivalent Influenza Vaccine in Subjects Aged 65 Years and Older

Influenza

United States
Sanofi

Completed

A Trial to Evaluate the Safety and Immunogenicity of ADACEL® Vaccine in Persons 65 Years of Age and Older

Pertussis | Tetanus | Diphtheria

United States
University of Pittsburgh
National Center for Research Resources (NCRR)

Completed

Mindfulness Meditation for Chronic Low Back Pain in Older Adults

Low Back Pain
Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.
Shenzhen Third People's Hospital; Wuhan Institute for Tuberculosis Control

Recruiting

Clinical Study of Recombinant Mycobacterium Tuberculosis Fusion Protein for 65-year-olds and Above

Latent Tuberculosis Infection

China
Centre Hospitalier Universitaire de Saint Etienne
Pierre Fabre Dermo Cosmetique

Terminated

Bioclinical Study of Scalp Photoaging of a Population Male Over 65 Years Old. (BACCHUS)

Skin Cancer | Skin Aging

France
Hand and Upper Limb Clinic, Canada
Canadian Orthopaedic Foundation

Unknown

Assessing Volar Locking Plates in Patients Under 65 With a Distal Radius Fracture (DRF)

Distal Radius Fracture

Canada
Meir Medical Center

Completed

Study of Erlotinib With Docetaxel in Selected Non Small Cell Lung Cancer Patients in First Line Treatment

Non-Small Cell Lung Cancer

Israel
Swiss Group for Clinical Cancer Research

Completed

Nelfinavir Mesylate and Bortezomib in Treating Patients With Relapsed or Progressive Advanced Hematologic Cancer

Lymphoma | Leukemia | Multiple Myeloma and Plasma Cell Neoplasm | Mature T-cell and Nk-cell Neoplasms

Switzerland
University Hospital, Angers

Completed

Assessment of Two Levels of Arterial Pressure on Survival in Patients With Septic Shock (SEPSISPAM)

Mortality | Septic Shock | Hemodynamics | Clinical Trial | Arterial Pressure

France
Aalborg University
Aalborg Municipality; Imasen Electrical Industrial Co., Ltd.

Completed

What Are the Effects of a Bilateral Hip Exoskeleton During Daily Use by 65+ Adults?

Pre-frail Senior Adults

Denmark
Rennes University Hospital

Completed

Efficacy of Continuous Apomorphine Infusion on Cognitive and Neuropsychological Functions in Parkinson's Disease (APO-TEP)

Parkinsons's Disease

France
Chinese University of Hong Kong

Completed

A Randomized Controlled Trial Evaluating an Online Intervention in Increasing Seasonal Influenza Vaccination Among Community Dwelling People Aged ≥65 Years

Vaccination Refusal

Hong Kong
AstraZeneca

Completed

Effect of Ciclesonide on Quality of Life in Patients With Moderate Persistent Asthma (21 to 65 y) (BY9010/AR-101)

Asthma

Argentina
Biophytis

Completed

An OBServational Clinical Trial (SARA-OBS) in Sarcopenia and Sarcopenic Obesity in Patients Aged 65 Years and Over (SARA-OBS)

Muscle Weakness | Sarcopenia | Gait Disorders in Old Age

Italy, United States, Belgium, France
Pharmacyclics LLC.
Janssen Research & Development, LLC

Completed

Open-label Phase 3 BTK Inhibitor Ibrutinib vs Chlorambucil Patients 65 Years or Older With Treatment-naive CLL or SLL

Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma

United States, Australia, Belgium, Canada, China, Czechia, Ireland, Israel, Italy, New Zealand, Poland, Russian Federation, Spain, Turkey, Ukraine, United Kingdom
Organon and Co

Completed

Ezetimibe and Atorvastatin vs. Atorvastatin in Patients Age 65 and Older at High Risk for Coronary Heart Disease (CHD)(0653-112)

Hypercholesterolemia
Poitiers University Hospital
Pfizer

Completed

Imaging for the Evaluation of Transthyretin Cardiac Amyloidosis Prevalence of Patients Over 65 Hospitalized in Cardiology Wards (the IMPACT Study) (IMPACT)

Transthyretin Cardiac Amyloidosis

France
Fundación Pública Andaluza para la Investigación...

Completed

15 Years Outcomes Following Bioprosthetic vs Mechanical Aortic Valve Replacement Between 50-65 Years (ANDALVALVE)

Surgery | Valve Heart Disease | Survival, Prosthesis

Spain
UNC Lineberger Comprehensive Cancer Center
Breast Cancer Research Foundation

Completed

The Effect of Walking on Fatigue After Chemotherapy in Patients 65 and Older (S-PACT)

Cancer | Fatigue | Geriatric

United States
Biosearch S.A.

Completed

Effects of Lactobacillus Coryniformis CECT5711 on Immune Response to Influenza Vaccination in Adults Over 65.

Immune Response | Probiotics | Influenza Vaccination
Poitiers University Hospital

Completed

The Life and Care of Colorectal Cancer Patients After 65 Years and Their Family (MACHROAPIK65)

Colorectal Cancer

France
Istinye University
The Scientific and Technological Research Council of Turkey

Not yet recruiting

Relationship Between Biomarkers and Biomechanical in Nonspecific Low Back Pain

Low Back Pain
Bayer

Completed

Study on the Safety of the Drug BAY2395840 at Different Doses, the Way the Body Absorbs, Distributes and Excretes the Drug Including the Effect of Its Formulation (Tablet or Liquid) and the Effect of Food on the Absorption, Distribution or Excretion of the Drug in Healthy Male Participants

Endometriosis

Germany
Baxalta now part of Shire

Completed

Efficacy and Safety Study of Prophylactic Versus On-Demand Treatment With Feiba NF in Subjects With Hemophilia A or B and a High Titer Inhibitor

Hemophilia A | Hemophilia B | Hemophilia A or B With Inhibitors

Poland, United States, Bulgaria, Romania, Japan, Russian Federation, New Zealand, Croatia, Ukraine, Brazil
Bayer
Merck Sharp & Dohme LLC; Duke Clinical Research Institute; Canadian VIGOUR Centre

Completed

Patient-reported Outcomes in Vericiguat-treated Patients With HFpEF (VITALITY-HFpEF)

Chronic Heart Failure With Preserved Ejection Fraction

Spain, United States, Belgium, Singapore, Taiwan, Canada, Japan, Italy, Austria, Bulgaria, Germany, Greece, Israel, Poland, Portugal, Hungary, Russian Federation, Argentina, Colombia, Malaysia, South Africa

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