Search clinical trials for: Older age

Total 199180 results

The Hong Kong Polytechnic University

Completed

Self-administered Acupressure for Knee Osteoarthritis in Middle- and Older-Aged Adults

Knee Osteoarthritis

Hong Kong
GlaxoSmithKline

Completed

Study to Evaluate Immunogenicity and Safety of GSK Biologicals' Herpes Zoster Subunit (HZ/su) Vaccine at 9 and 10 Years After Vaccine Administration and Assessment of Re-vaccination With 2 Additional Doses at 10 Years After Initial Vaccination, in Healthy Subjects Aged 60 Years of Age(YOA) and Older

Herpes Zoster

Germany, Czechia, Sweden
Tufts University

Completed

StrongWomen- Healthy Hearts: A Community Based Program for Midlife and Older Women

Cardiovascular Diseases | Overweight and Obesity
Vertex Pharmaceuticals Incorporated

Enrolling by invitation

Evaluation of Long-Term Safety and Efficacy of Vanzacaftor/Tezacaftor/Deutivacaftor in Cystic Fibrosis Participants 1 Year of Age and Older

Cystic Fibrosis

United States, Australia, Germany, Sweden, Switzerland, France, Netherlands, United Kingdom
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Active, not recruiting

Testing the Effects of MK-3475 (Pembrolizumab) With or Without the Usual Chemotherapy Treatment for Patients 70 Years of Age and Older With Advanced Non-small Cell Lung Cancer

Metastatic Lung Non-Small Cell Carcinoma | Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Metastatic Lung Adenocarcinoma | Recurrent Lung Non-Small Cell Carcinoma | Recurrent Lung Adenocarcinoma

United States
GlaxoSmithKline

Completed

A Study on the Immune Response and Safety of a Vaccine Against Herpes Zoster in Adults Aged 50 Years and Older in India

Herpes Zoster

India
Oslo Metropolitan University
Oslo Municipality; No Isolation limited

Active, not recruiting

Effectiveness of a Communication Device in Home Care Services in Norway: Does Komp Make Older Adults Feel Happier, Safer and More Connected, and Able to Live Longer at Home. (BoVEL)

Quality of Life | Dementia | Well-being | Mental Health | Older Adults | Loneliness | Technology | Safety | Social Isolation | Home Care | Feeling Anxious

Norway
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Ibrutinib and Rituximab in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma or Older Patients With Newly Diagnosed Mantle Cell Lymphoma

Recurrent Mantle Cell Lymphoma | Mantle Cell Lymphoma | CCND1 Positive | CCND2 Positive | CCND3 Positive | CD20 Positive | Refractory Mantle Cell Lymphoma

United States
Sanofi Pasteur, a Sanofi Company

Completed

Safety and Immunogenicity of Quadrivalent Influenza mRNA Vaccine MRT5407 in Adult Participants18 Years of Age and Older

Influenza Immunization

Puerto Rico, United States
National Taiwan University Hospital

Active, not recruiting

Effects of Intervention on Hope, Anxiety, and Attitudes and Behavioral Intentions of Advance Care Planning in Older Adults With Cancer (ACP)

Advance Care Planning

Taiwan
Otsuka Pharmaceutical Development & Commercialization...

Completed

Assessment of the Efficacy, Safety, and Tolerability of AVP-786 (Deudextromethorphan Hydrobromide [d6-DM]/Quinidine Sulfate [Q]) for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type

Agitation in Patients With Dementia of the Alzheimer's Type

Spain, United States, Italy, United Kingdom, Hungary, France, Poland, Australia, Bulgaria, Czechia, South Africa
University of Michigan
National Institute on Aging (NIA)

Completed

Neurobiological Drivers of Mobility Resilience: The Dopaminergic System (RES)

Parkinsonian Signs in Older Persons

United States
Pfizer

Completed

A Study to Evaluate a Modified RNA Vaccine Against Influenza in Adults 18 Years of Age or Older

Influenza, Human

United States, Brazil, South Africa, Philippines, New Zealand, Chile, Argentina
Seqirus

Completed

Safety and Immunogenicity of Different Formulations of an MF59-Adjuvanted Influenza Vaccine in Older Adults ≥50 Years of Age

Influenza, Human

United States
Oregon Research Institute

Active, not recruiting

Tai Ji Quan and Cognitive Function in Older Adults With Mild Cognitive Impairment

Mild Cognitive Impairment

United States
University of Colorado, Denver
National Institute on Aging (NIA)

Active, not recruiting

Longitudinal Innate Immunity and Aging Study (LIIA)

Healthy Older Adults Ages 60-89

United States
Mayo Clinic

Suspended

Improve the Patients' Recovery With Family- Caregivers to End Delirium (iPREPARED)

Delirium

United States
USDA Human Nutrition Research Center on Aging
California Strawberry Commission

Completed

The Effects of Strawberry Supplementation on Memory and Gait Among Over-weight Older Adults

Obesity | Aging | Age-related Cognitive Decline

United States
Sundeep Khosla, M.D.

Active, not recruiting

Targeting Cellular Senescence With Senolytics to Improve Skeletal Health in Older Humans

Healthy

United States
Pfizer

Completed

A Study to Learn About a Repeat 5-Day Treatment With the Study Medicines (Called Nirmatrelvir/Ritonavir) in People 12 Years Old or Older With Return of COVID-19 Symptoms and SARS-CoV-2 Positivity After Finishing Treatment With Nirmatrelvir/Ritonavir

COVID-19

United States, Taiwan, Italy, Canada, Greece
Seqirus

Active, not recruiting

The Celljuvant Study: A Phase 3 Immunogenicity and Safety Study of aQIVc Vaccine in Adults Aged 50 Years and Older

Influenza, Human

Philippines, United States, Germany, Pakistan, Canada, Estonia, Denmark, United Kingdom
University of Alberta
Alberta Health services

Enrolling by invitation

Antihypertensive Deprescribing in Long-term Care (OptimizeBP)

Hypertension | Frailty

Canada
Vertex Pharmaceuticals Incorporated

Completed

Evaluation of Long-term Safety and Efficacy of VX-445 Combination Therapy in Subjects With Cystic Fibrosis Who Are 6 Years of Age and Older

Cystic Fibrosis

United States, Canada, Australia, Ireland, United Kingdom
ModernaTX, Inc.
National Institute of Allergy and Infectious Diseases (NIAID); Biomedical Advanced...

Completed

A Study to Evaluate Efficacy, Safety, and Immunogenicity of mRNA-1273 Vaccine in Adults Aged 18 Years and Older to Prevent COVID-19

SARS-CoV-2

United States
University of Salamanca

Active, not recruiting

Effectiveness of Power Training in Older Women With Pre-sarcopenia (POSARC)

Old Age; Debility | Pre-sarcopenia

Spain
Nantong University
Chiang Mai University

Completed

Effectiveness of Health Literacy Enhancement Program Among Older Persons With Physical Multimorbidity

Multiple Chronic Conditions；Diabetes；Hypertension

China
Loughborough University
University of Leeds; Aston University; Food4Years Ageing Network

Completed

Oral Nutritional Supplementation and Community-dwelling Older Adults: a Feasibility Study (SPOONful)

Malnutrition | Healthy Aging

United Kingdom
University of Tromso
University of Oslo; Novo Nordisk A/S; University Hospital of North Norway; The... and other collaborators

Active, not recruiting

RE-inventing Strategies for Healthy Ageing; Recommendations and Tools (RESTART)

Muscle Weakness | Diet, Healthy | Self Efficacy | Lifestyle, Healthy | Abdominal Obesity | Cardiometabolic Syndrome

Norway
Maastricht University Medical Center

Completed

Quality of Life in Middle-aged and Older Patients With Congenital Ichthyosis

Congenital Ichthyosis

Netherlands
Sanofi Pasteur, a Sanofi Company

Completed

Study on Two Adjuvanted Dose Levels of Panblok H7+MF59 Compared for Immunogenicity and Safety With an Unadjuvanted Dose of Panblok H7 in Participants 18 Years of Age and Older

Influenza | Healthy Volunteers

United States
The University of Texas Health Science Center at...
National Institute on Aging (NIA)

Completed

Metformin for Preventing Frailty in High-risk Older Adults

Frailty

United States
Merck Sharp & Dohme LLC

Active, not recruiting

Study of Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy for HR+/HER2- Locally Recurrent Inoperable or Metastatic Breast Cancer (MK-3475-B49/KEYNOTE-B49)

Breast Neoplasms

Korea, Republic of, Germany, United States, United Kingdom, Argentina, Australia, Austria, Brazil, Canada, Chile, China, Colombia, France, Greece, Guatemala, Hungary, Ireland, Israel, Italy, Japan, Malaysia, Mexico, Netherlands, Phili... and more
Jonsson Comprehensive Cancer Center
Genentech, Inc.

Completed

Bevacizumab and Temozolomide in Treating Older Patients With Newly-Diagnosed Glioblastoma Multiforme or Gliosarcoma

Glioblastoma | Gliosarcoma | Giant Cell Glioblastoma

United States
Radboud University Medical Center

Active, not recruiting

The Effect of a Combined Personalized Nutritional Intervention and a Personalized Graded Activity Functional Training Program on Physical Performance in Hospitalized Older Patients, Compared to Usual Care (FITFOOD)

Old Age; Atrophy

Netherlands
The Hong Kong Polytechnic University

Completed

The Effects of a Tele-health Program

Frailty | Old Age; Debility

Hong Kong
University of Glasgow

Active, not recruiting

A Comparison of the Effects of Krill Oil and Fish Oil Supplementation on Muscle Function in Older Adults

Sarcopenia

United Kingdom
Grupo Español de Linfomas y Transplante Autólogo...
Takeda

Active, not recruiting

BrEPEM-LH-22017 for Older Patients With Untreated Hodgkin Lymphoma (HL)

Hodgkin Lymphoma

Spain
Hipra Scientific, S.L.U

Completed

A Phase II Trial to Evaluate the Safety and Immunogenicity of BIMERVAX® When Coadministered With Seasonal Influenza Vaccine (SIIV) in Adults Older Than 65 Years of Age Fully Vaccinated Against COVID-19

Influenza, Human | SARS CoV 2 Infection

Spain
BioAge Labs, Inc.

Completed

Pharmacokinetics Study of Azelaprag (BGE-105) in Older Adult Healthy Volunteers

Healthy Volunteer Study

New Zealand
Jewish General Hospital

Active, not recruiting

Effects of Montreal Museum of Fine Arts Visits and Older Community Dwellers With a Precarious State

Old Age | Well Aging | Social Isolation | Health Impairment

Canada
Jewish General Hospital

Active, not recruiting

Risk for Short-term Adverse Events in Older Users in the Emergency Department

Old Age | Survey | Medical Care

Canada
Indiana University
National Institute on Aging (NIA)

Active, not recruiting

Decreasing Delirium Through Music in Critically Ill Older Adults (DDM)

Pain | Anxiety | Intensive Care Unit Delirium | Intensive Care Acquired Cognitive Impairment

United States
University of Alabama at Birmingham
National Cancer Institute (NCI); University of Tennessee

Active, not recruiting

Adapting Multiple Behavior Interventions That Effectively Improve Cancer Survivor Health Cancer Survivor Health (AMPLIFY)

Kidney Cancer | Breast Cancer | Multiple Myeloma | Colorectal Cancer | Prostate Cancer | Non-Hodgkin Lymphoma | Endometrial Cancer | Thyroid Cancer | Ovary Cancer

United States
University of Florida

Active, not recruiting

Accelerated Dose Schedule of Cytarabine Consolidation Therapy for Older Patients With Acute Myeloid Leukemia (AML) in Complete Remission

Acute Myeloid Leukemia

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Nab-Paclitaxel in Treating Older Patients With Locally Advanced or Metastatic Breast Cancer

Recurrent Breast Carcinoma | Stage IV Breast Cancer AJCC v6 and v7 | Stage III Breast Cancer AJCC v7 | Stage IIIA Breast Cancer AJCC v7 | Stage IIIB Breast Cancer AJCC v7 | Stage IIIC Breast Cancer AJCC v7 | Metastatic Breast Carcinoma | Locally Advanced Breast Carcinoma

United States
Swiss Federal Institute of Technology

Completed

Feasibility and Effectiveness of a Home-based Motor-cognitive Training Program in Older Adults (COCARE)

Aged | Independent Living

Switzerland
Nguyen Dang Thu

Completed

CPAP on Oxygenation and Pulmonary Function in Elderly Patients After Major Open Abdominal Surgery (CPAP)

Older People | Pulmonary Function | Continuous Positive Airway Pressure

Vietnam
Nami Safai Haeri
National Institute on Aging (NIA); The Claude D. Pepper Older Americans Independence...

Active, not recruiting

Muscle Impact of Treating Osteoporosis (MITO)

Sarcopenia | Osteoporosis

United States
H. Lee Moffitt Cancer Center and Research Institute
Janssen Scientific Affairs, LLC

Active, not recruiting

Daratumumab Based Response Adapted Therapy for Older Adults With Newly Diagnosed Multiple Myeloma

Multiple Myeloma

United States
Janssen Vaccines & Prevention B.V.

Completed

A Study of an Adenovirus Serotype 26 Pre-fusion Conformation-stabilized F Protein (Ad26. RSV. preF) Based Respiratory Syncytial Virus (RSV) Vaccine in the Prevention of Lower Respiratory Tract Disease in Adults Aged 60 Years and Older (EVERGREEN)

Respiratory Syncytial Viruses | Lower Respiratory Tract Disease

United States, Taiwan, Thailand, Canada, Poland, United Kingdom, Brazil, Chile, New Zealand, Estonia, Finland, South Africa, Australia, China

Search clinical trials for: Older age

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