Search clinical trials for: Phase I study

Total 496079 results

The University of Hong Kong

Recruiting

KeySteps@JC Phase Two Study

Lifestyle Modification

Hong Kong
CNBG-Virogin Biotech (Shanghai) Ltd.

Recruiting

A PhaseⅡ Study to Evaluate the Safety and Immunogenicity of COVID-19 Vaccine

SARS-CoV-2 Infection

China
CNBG-Virogin Biotech (Shanghai) Ltd.
Shulan (Hangzhou) Hospital

Recruiting

A Phase 1 Study to Evaluate the Safety and Immunogenicity of COVID-19 Vaccine

SARS-CoV-2 Infection

China
Sling Therapeutics, Inc.

Recruiting

A Phase 2b Extension Study of Two Doses of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED)

Eye Diseases | Endocrine System Diseases | Thyroid Diseases | Thyroid Eye Disease | Graves Ophthalmopathy | Exophthalmos | Orbital Diseases | Thyroid Associated Ophthalmopathy | Graves Orbitopathy | Proptosis | IGF1R | Hashimoto

United States
Abbisko Therapeutics Co, Ltd

Recruiting

A Phase 2 Study of ABSK021 in Patients With Advanced Pancreatic Cancer

Advanced Pancreatic Cancer

China
Jiangsu Hansoh Pharmaceutical Co., Ltd.

Not yet recruiting

A Study of HS-10241 Combined With Almonertinib Versus Platinum-based Chemotherapy in Treatment of Advanced NSCLC With MET Amplification After Failure of EGFR-TKI Therapy

Non-Small Cell Lung Cancer
AstraZeneca
Daiichi Sankyo

Recruiting

A Phase III Randomised Study to Evaluate Dato-DXd and Durvalumab for Neoadjuvant/Adjuvant Treatment of Triple-Negative or Hormone Receptor-low/HER2-negative Breast Cancer

Breast Cancer

China, United States, Italy, Spain, United Kingdom, Korea, Republic of, Canada, Germany, Poland, Belgium, Japan, Vietnam, Bulgaria, France, Brazil, India, Malaysia, Taiwan, Thailand, Hungary, Australia, Austria, Turkey, Hong Kong, Switz... and more
Shanghai Hengrui Pharmaceutical Co., Ltd.

Recruiting

A Phase I Clinical Study of SHR-2005 Intravesical Instillation in the Treatment of High-risk Non-muscle Invasive Bladder Cancer (NMIBC)

High-risk Non-muscle Invasive Bladder Cancer

China
Wandercraft

Recruiting

Effects of Atalante Exoskeleton on Gait Recovery in Non- or Poorly Ambulatory Patients With Hemiparesis in the Acute/Subacute Phase (Month 1 to 4) (EarlyExo)

Cerebrovascular Disorders | Stroke, Ischemic | Stroke, Acute | Stroke Hemorrhagic | Hemiparesis | Cerebrovascular Accident | Hemiparesis;Poststroke/CVA | Stroke, Subacute | Hemiparesis/Hemiplegia (One Sided Weakness/Paralysis)

Germany, France, Spain
Valneva Austria GmbH

Recruiting

A Phase 2 Clinical Study of VLA1553 in Healthy Children Aged 1 to 11 Years

Chikungunya Virus Infection

Dominican Republic, Honduras
Corcept Therapeutics

Recruiting

A Phase 2b, Study Evaluating Miricorilant in Adult Patients With Nonalcoholic Steatohepatitis/Metabolic Dysfunction-Associated Steatohepatitis (MONARCH)

Nonalcoholic Steatohepatitis (NASH) | Metabolic Dysfunction-associated Steatohepatitis (MASH)

United States, Puerto Rico
ProMis Neurosciences, Inc

Recruiting

A Phase 1a Study of PMN310 In Healthy Volunteers

Healthy Participants

United States
AstraZeneca
Daiichi Sankyo

Recruiting

A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer

Breast Cancer

United States, Spain, China, Italy, Australia, United Kingdom, Korea, Republic of, Vietnam, Japan, Turkey, Brazil, Taiwan, Thailand, Canada, Argentina, India, France, Singapore, Mexico, Germany, Philippines, Poland, South Africa
Amgen

Recruiting

A Study to Evaluate the Efficacy and Safety of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-severe Systemic Disease Activity

Sjogren's Syndrome

United States, Argentina, Japan
M.D. Anderson Cancer Center
Sanofi US Services, Inc

Recruiting

Phase I/II Open Label Study of Belumosudil Mesylate Alone, and in Combination With Dexamethasone, in Patients With Relapsed/Refractory Multiple Myeloma

Multiple Myeloma

United States
Affini-T Therapeutics, Inc.

Recruiting

Phase I Study of Autologous CD8+ and CD4+ Engineered T Cell Receptor T Cells in Subjects With Advanced or Metastatic Solid Tumor

Colorectal Cancer | Non-Small Cell Lung Cancer | Solid Tumor | Pancreatic Ductal Adenocarcinoma | KRAS G12V

United States
Instituto Valenciano de Infertilidad, IVI VALENCIA

Recruiting

Second Phase of the Pilot Study for Obtaining Mature Oocytes by in Vitro Maturation in Oocyte-donor Women (MIVODON-II)

Infertility, Female | Oocyte Maturation

Spain
Funan Liu
Institute of Health and Medical Technology, Hefei Institutes of Physical... and other collaborators

Recruiting

A Clinical Study Aims to Assess the Consistency of Clinical Efficacy in Gastric Cancer Treatment and Drug Susceptibility Outcomes Using a Novel Drug Susceptibility Testing Method

Gastric Cancer | Organoids

China
China Medical University, China
Shanghai First Song Therapeutics Co., Ltd

Recruiting

A Clinical Study Evaluating the Safety and Efficacy of Anti-HER2-CAR-T Cells Injection in Patients With Solid Tumors

Solid Tumor

China
Edgewise Therapeutics, Inc.

Recruiting

Phase 2 Study of EDG-5506 in Children and Adolescents With Duchenne Muscular Dystrophy Previously Treated With Gene Therapy (FOX)

Duchenne Muscular Dystrophy

United States
Funan Liu
Institute of Health and Medical Technology, Hefei Institutes of Physical... and other collaborators

Recruiting

A Clinical Study Aims to Assess the Consistency of Clinical Efficacy in Colorectal Cancer Treatment and Drug Susceptibility Outcomes Using a Novel Drug Susceptibility Testing Method

Colorectal Cancer | Organoids

China
ITabMed Co., Ltd.

Not yet recruiting

An Exploratory Study of A-337 in the Management of Malignant Solid Dose Escalation and Expansion Phases (A-337)

Recurrent or Metastatic Solid Tumors
Anwita Biosciences

Recruiting

Phase 1 Study of AWT020 in Advanced Cancer

Advanced Cancer

Australia
Shanghai Junshi Bioscience Co., Ltd.

Recruiting

Phase 3 Study of Toripalimab Alone or in Combination With Tifcemalimab as Consolidation Therapy in Patients With Limited-stage Small Cell Lung Cancer (LS-SCLC)

Limited-stage Small Cell Lung Cancer (LS-SCLC)

China, France, United States, Spain, Taiwan, Korea, Republic of, Turkey, Italy, Netherlands, Georgia, Germany, Belgium, Poland, Romania
Akeso

Not yet recruiting

A Phase II Study to Evaluate the Safety and Efficacy of AK120 in Subjects With Moderate to Severe Atopic Dermatitis

Atopic Dermatitis

China
AbbVie

Not yet recruiting

Study of Intravenous Telisotuzumab Vedotin in Combination Osimertinib or Standard of Care Chemotherapy to Assess Change in Disease Activity in Adult Participants With Non-Small Cell Lung Cancer That Has a Mutation in the Epidermal Growth Factor Receptor Gene and That Overexpresses the c-Met Protein

Non-Small Cell Lung Cancer
Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Not yet recruiting

A Phase IB/II Clinical Study of SHR-A2009 for Injection in Combination With Other Antitumor Therapies in Patients With Advanced Solid Tumors

Advanced Solid Tumors
JCR Pharmaceuticals Co., Ltd.

Recruiting

Phase I/II Study of JR-441 in Patients With Mucopolysaccharidosis Type IIIA

Mucopolysaccharidosis III-A

Germany
University Hospital Tuebingen
Cooperative Weichteilsarkom Study Group; Deutsches Konsortium fürTranslationale... and other collaborators

Recruiting

Personalized Vaccination in Fusion+ Sarcoma Patients (PerVision) (PerVision)

Ewing Sarcoma | Rhabdomyosarcoma | Synovial Sarcoma

Germany
Octapharma

Not yet recruiting

Phase 3 Study on the Efficacy and Safety of Human Plasma Derived Antithrombin (Atenativ) in Heparin-resistant Patients Scheduled to Undergo Cardiac Surgery Necessitating Cardiopulmonary Bypass

Acquired Antithrombin Deficiency
Fudan University

Not yet recruiting

A Phase II Study of T-DXd Plus SRT in HER2-positive Breast Cancer Brain Metastases

Breast Cancer | Brain Metastases | Radiotherapy

China
Beijing Luzhu Biotechnology Co., Ltd.

Recruiting

A Phase Ⅲ Clinical Study to Evaluate Protective Efficacy and Safety of a Recombinant Herpes Zoster Vaccine

Herpes Zoster | Vaccine-Preventable Diseases

China
Suzhou Abogen Biosciences Co., Ltd.

Recruiting

Phase Ⅰ/Ⅱ Clinical Study to Evaluate ABO2011 Monotherapy in Advanced Solid Tumors

Solid Tumor, Adult

China
Innate Pharma

Recruiting

Phase1/2 Study of IPH6501 in Patients With Relapsed /Refractory B-Cell Non-Hodgkin Lymphoma

Non Hodgkin Lymphoma

France, United States, Australia
University of Pittsburgh
Agency for Healthcare Research and Quality (AHRQ)

Recruiting

Pilot Testing PICTURE-THIS

Critical Care | Health Services | Transitional Care | Post-intensive Care Syndrome

United States
University of Illinois at Chicago

Recruiting

BRE-08 Phase II Study of CMC Regimen for Early Stage Breast Cancer (BRE-08)

Breast Cancer

United States
M.D. Anderson Cancer Center

Recruiting

Phase I/II Study of PEGylated Arginine Deiminase (ADI-PEG20) With Carboplatin and Cabazitaxel in Men With Aggressive Variant Prostate Cancers (AVPC)

Prostate Cancer

United States
M.D. Anderson Cancer Center
Bayer

Not yet recruiting

Phase 2 Study to Evaluate the Efficacy of Regorafenib in Specific GIST Mutation Subsets (KIT Exon 17, 18, or 14 Mutation and SDHB Deficient GIST) in the Post-imatinib Second-line Setting.

Gastrointestinal Stromal Tumors

United States
IGM Biosciences, Inc.

Recruiting

A Phase 1b Study of Imvotamab in Moderate to Severe Rheumatoid Arthritis

Arthritis | Arthritis, Rheumatoid | Rheumatoid Arthritis

United States, Poland
Praxis Precision Medicines

Recruiting

Essential 3 - Decentralized, Phase 3 Study Evaluating the Safety and Efficacy of Ulixacaltamide in Essential Tremor (ET)

Essential Tremor

United States
Peking Union Medical College Hospital

Recruiting

Phase I/II Study of Linperlisib Plus Chidamide for R/R Peripheral T-cell Lymphoma: a Prospective, Multi-center Study

Peripheral T Cell Lymphoma

China
M.D. Anderson Cancer Center

Recruiting

Phase I/Ib Study of NK Expressing an Affinity-enhanced T-cell Receptor (TCR) Against the NY-ESO-1

Myxoid/Round Cell Liposarcoma | Synovial Sarcoma

United States
AstraZeneca

Recruiting

A Phase I/II Study to Evaluate AZD5851 in GPC3+ Advanced/Recurrent Hepatocellular Carcinoma (ATHENA)

Hepatocellular Carcinoma

United States, Korea, Republic of
Sichuan Kelun Pharmaceutical Research Institute...

Not yet recruiting

A Phase III Study of SKB264 for Locally Advanced, Recurrent or Metastatic HR+/HER2- Breast Cancer

Metastatic Breast Cancer
Cancer Institute and Hospital, Chinese Academy...

Recruiting

A Prospective, Open-label, Multicenter, Randomized Controlled Phase III Study of Prophylactic Central Neck Dissection in Low-risk Papillary Thyroid Cancer

Recurrence | Thyroid Cancer

China
Sinotau Pharmaceutical Group

Recruiting

Study of [177Lu] Lu-XT033 Injection in Patients With Metastatic Prostate Cancer

Prostate Cancer

China
Gilead Sciences

Recruiting

Study of GS-9911 With or Without Antibody Treatment for Adults With Solid Tumors

Solid Tumors

Australia, United States, Canada
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Phase III Study Comparing GVHD Prophylaxis With ATG-thymoglobulin to ATLG-grafalon in Elderly Patients With Acute Myeloid Leukemia or Myelodysplasic Syndrome and Receiving an Allogeneic Hematopoietic Stem Cell Transplantation With a 10/10 HLA Matched Unrelated Donor (OPTISAGE)

GVHD
Zhejiang Vimgreen Pharmaceuticals, Ltd.
Tigermed Consulting Co., Ltd

Recruiting

A Phase I Study of Single and Multiple Doses of VG290131 in Healthy Subjects

Healthy Volunteers

Australia
Jemincare
Zhejiang Hangyu Pharmaceutical Co., Ltd

Recruiting

Phase 1 Clinical Study of JMKX003142 Tablets

Safety and Tolerability

China

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