Search clinical trials for: Pragmatic clinical trial

Total 82045 results

Mayo Clinic

Recruiting

Clinical and Molecular Characteristics of Histiocytic Disorders

Histiocytic Disorder

United States
Ain Shams University

Recruiting

The Efficiency of Clear Aligners in Maxillary Molar Distalization: A Randomized Clinical Trial. (Aligner)

Orthodontic Aligners

Egypt
Chiesi Farmaceutici S.p.A.
ICON plc

Not yet recruiting

A Study to Learn About the Safety and Effects of the Study Drug PRX-102 in Children and Adolescents With Fabry Disease (FLY)

Fabry Disease
Mayo Clinic

Recruiting

Determination of Baseline Levels for Prostate Cancer-Derived Extracellular Vesicles Following Local Treatment of Prostate Cancer

Prostate Carcinoma

United States
Mayo Clinic

Not yet recruiting

Evaluating Changes in Quality of Life After Near Margin-less Adaptive Radiation Therapy Compared to Standard Stereotactic Ablative Body Radiotherapy in Localized Prostate Cancer

Stage I Prostate Cancer AJCC v8 | Stage II Prostate Cancer AJCC v8 | Stage III Prostate Cancer AJCC v8 | Localized Prostate Adenocarcinoma

United States
Christoph Berger

Not yet recruiting

A Trial of Placebo Versus Macrolide for Mycoplasma Pneumoniae Childhood Pneumonia: MYTHIC Study (MYTHIC)

Community Acquired Pneumonia in Children | Mycoplasma Pneumoniae | Mycoplasma Pneumoniae Pneumonia

Switzerland
Novo Nordisk A/S

Recruiting

A Research Study Comparing How Well Different Doses of the Medicine NN0519-0130 Lower Blood Sugar in People With Type 2 Diabetes

Diabetes Mellitus, Type 2

United States, Korea, Republic of, Australia, India, Canada, Japan, South Africa
European Institute of Oncology

Recruiting

What Unmet Need for the Patients?A Focus on the Social Determinants of Health in Phase 1 Clinical Trials

Solid Tumor

Italy
Beijing GoBroad Hospital

Not yet recruiting

Safety, Tolerability, and Pharmacokinetics of Donor-derived CD19 CAR Therapy Bridged Allo-HSCT and Sequential Donor-derived CD22 CAR Therapy for r/r B-ALL: a Clinical Trial

Acute Lymphoblastic Leukemia, in Relapse | B-cell Acute Lymphoblastic Leukemia
Pfizer

Recruiting

A Study to Learn About the Vaccine RSVpreF In Pregnant Participants With HIV and Their Infants (MORISOT)

Respiratory Syncytial Virus

South Africa
Abbisko Therapeutics Co, Ltd

Not yet recruiting

A Clinical Trial to Evaluate a High-Fat Meal and Omeprazole Enteric-coated Tablets on ASBK021

Healthy Subjects
Mayo Clinic

Recruiting

Acupressure for Reducing Anxiety in Patients Undergoing Chemotherapy

Malignant Solid Neoplasm | Hematopoietic and Lymphatic System Neoplasm

United States
Boehringer Ingelheim

Recruiting

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib in Combination With Trastuzumab Deruxtecan or With Trastuzumab Emtansine and to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

Metastatic Breast Cancer | Esophageal Adenocarcinoma | Metastatic Gastric Adenocarcinoma | Gastroesophageal Junction Adenocarcinoma

United States
Novo Nordisk A/S

Recruiting

A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in People With Type 2 Diabetes Treated With Diet and Exercise (REIMAGINE 1)

Type 2 Diabetes

United States, Serbia, Italy, China, Poland, Hungary, Saudi Arabia
H. Lundbeck A/S

Recruiting

A Dose-finding Trial With Lu-AG09222 in Adults With Migraine Who Have Not Been Helped by Prior Preventive Treatments (PROCEED)

Migraine

United States
Mayo Clinic

Recruiting

Ommaya Reservoir Placement at the Time of Biopsy for Longitudinal Biomarker Collection in Patients With Brain Tumors

Brain Neoplasms

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Women's Refusal to Participate in a Randomized Trial Involving First-trimester Screening for Pre-eclampsia: Factors Associated With Refusal and Reasons for Acceptance and Refusal (RANSPRE-refus)

Pregnancy Related

France
Novo Nordisk A/S

Recruiting

A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in People With Type 2 Diabetes Treated With Once-daily Basal Insulin With or Without Metformin (REIMAGINE 3)

Type 2 Diabetes

United States, Japan, Serbia, South Africa, China, Slovakia
GlaxoSmithKline

Recruiting

A Study of TSR-022 in Participants With Advanced Solid Tumors (AMBER)

Neoplasms

United States, Spain, Korea, Republic of
Visirna Therapeutics HK Limited

Not yet recruiting

A Phase 2 Clinical Trial to Evaluate the Efficacy and Safety of VSA006 in Chinese NASH Patients

Nash
Shanghai JMT-Bio Inc.

Not yet recruiting

Efficacy and Safety of JMT101 Combined Wth Docetaxel / HB1801 in Patients With Squamous Cell Non-Small Cell Lung Cancer

Squamous Cell Non-small Cell Lung Cancer
Hospices Civils de Lyon

Not yet recruiting

Characterization of New Phenotypes of Patients With Spinal Muscular Atrophy Treated With SMN Restoring Therapy (PHENO SMART)

Spinal Muscular Atrophy

France
Dana-Farber Cancer Institute
ImmunityBio, Inc.

Not yet recruiting

Intraperitoneal Cytokine-Induced Memory Like (CIML) Natural Killer (NK) Cells in Recurrent Ovarian Cancer

Ovarian Cancer | Platinum-resistant Ovarian Cancer | Ovarian Carcinoma | Recurrent Ovary Cancer | Ovarian Carcinoma, Recurrent

United States
Carsten Dirksen
University of Copenhagen; University of Oxford; University of Bristol; University... and other collaborators

Recruiting

Intensive Weight Loss Intervention Versus Usual Care for Adults With Severe and Complex Obesity (LightWAY)

Obesity

Denmark, United Kingdom
Carsten Dirksen
University of Copenhagen; University of Oxford; University of Bristol; University... and other collaborators

Not yet recruiting

Intensive Weight Loss Intervention Versus Usual Care for Adults With Obesity (LightCARE)

Obesity

Denmark, United Kingdom
GlaxoSmithKline

Not yet recruiting

A Study to Evaluate the Efficacy and Safety of GSK3915393 in Participants With Idiopathic Pulmonary Fibrosis (IPF)

Idiopathic Pulmonary Fibrosis
GlaxoSmithKline

Recruiting

A Study of Dostarlimab in Combination With Carboplatin-paclitaxel in Japanese Participants With Primary Advanced or Recurrent Endometrial Cancer (RUBY-J)

Carcinoma

Japan
89bio, Inc.

Recruiting

A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)

Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis

United States
MB PHARMA s.r.o.

Recruiting

Clinical Trial to Demonstrate the Safety and Efficacy of DUOFAG®

Bacterial Infections | Surgical Wound Infection | Surgical Site Infection | Staphylococcus Aureus Infection | Pseudomonas Aeruginosa Infection

Czechia
Cybrexa Therapeutics

Not yet recruiting

A Study of CBX 12 in Subjects With Platinum Resistant or Refractory Ovarian Cancer

Platinum-resistant Ovarian Cancer | Refractory Ovarian Carcinoma
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Institutes of Health (NIH)

Not yet recruiting

A Clinical Trial to Assess PVX7 Immunotherapy Regimens in Advanced Cervical Cancer Patients

Cervical Cancer
Haukeland University Hospital

Recruiting

Dialectical Behavior Therapy for Adolescents With Self-harm and Suicidal Behavior- an Open Trial

Suicidal Ideation | Self-harm | Suicide and Self-harm

Norway
Ohio State University Comprehensive Cancer Center
National Cancer Institute (NCI)

Recruiting

Outreach Project to Connect Underrepresented Populations to Clinical Trials at Ohio State University, CUSP2CT Project Trial

Malignant Solid Neoplasm | Hematopoietic and Lymphoid System Neoplasm

United States
Mayo Clinic
National Cancer Institute (NCI); National Institute for Biomedical Imaging...

Recruiting

Improvements in Dynamic Contrast-Enhanced MR Angiography and Perfusion

Prostate Neoplasm

United States
Sanofi Pasteur, a Sanofi Company

Recruiting

Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne

Acne

United States
Beijing Tiantan Hospital

Not yet recruiting

Ticagrelor With Aspirin Dual Antiplatelet Therapy Combined With Intravenous Thrombolysis for Ischemic Stroke (TAPIS)

Ischemic Stroke, Acute
Bayer

Recruiting

An Observational Study to Collect Data on How Aflibercept (Eylea) Given Using a Paediatric Dosing Device is Used in Preterm Babies With Retinopathy of Prematurity in the United Kingdom (UK)

Preterm Infants | Retinopathy of Prematurity

United Kingdom
Vastra Gotaland Region
Göteborg University; Chalmers University of Technology; Gothia Forum - Center...

Not yet recruiting

Inter-organizational Health Planning for Older Adults: Public Dental Care and Municipal Care (GAPA)

Oral Health | Participation, Patient | Participation | Oral Health Related Quality of Life | Health Planning

Sweden
ViiV Healthcare
GlaxoSmithKline

Not yet recruiting

First Time in Human Study of Long Acting VH4524184 Formulations

HIV Infections

United States
LEO Pharma

Recruiting

A Trial to Evaluate the Efficacy and Safety of Tralokinumab in Combination With Topical Corticosteroids in Children and Infants With Moderate-to-severe Atopic Dermatitis (TRAPEDS 2)

Atopic Dermatitis

United States
VA Office of Research and Development

Not yet recruiting

At-Home Exercise Study for Veterans With Healed Diabetic Foot Ulcers

Diabetic Foot Ulcer

United States
Ain Shams University

Recruiting

The Adjunctive Role of Vitamin C on Pigment Recurrence (Randomized Clinical and Histological Trial)

Gingival Pigmentation

Egypt
Le Yu

Recruiting

Ciprofol Versus Propofol for Anesthesia Induction in Cardiac Surgery: A Randomized Double-blind Controlled Clinical Trial

Anesthesia

China
Eli Lilly and Company

Recruiting

A Study to Measure Calorie Consumption and Usage in Participants With Obesity Using LY3437943

Obesity

United States
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Recruiting

DP303c Versus Trastuzumab Emtansine in in Patients With HER2-positive Advanced Breast Cancer

HER2-positive Breast Cancer

China
DICE Therapeutics, Inc., a wholly owned subsidiary...
Eli Lilly and Company

Recruiting

A Study to Evaluate Safety, Tolerability of LY4100511 (DC-853) in Healthy Asian and Non-Asian Participants

Healthy

United States
Merck Sharp & Dohme LLC

Recruiting

A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)

Non Small Cell Lung Cancer

United States, Israel, Taiwan, Korea, Republic of, Switzerland, Hong Kong
ViiV Healthcare

Recruiting

A Study to Investigate the Potential Drug-Drug Interaction Between VH4524184 and Oral Contraceptive (Loestrin) in Healthy Adult Female Participants

HIV Infections

United States
Riphah International University

Recruiting

Combined Effects of Virtual Reality and Motor Imagery Techniques With Routine Physical Therapy in Post Stroke Patients

Stroke

Pakistan
Zhejiang Cancer Hospital

Not yet recruiting

Eribulin Combined With Sintilimab as First-line Treatment for Unresectable Locally Advanced or Metastatic HER2-negative Breast Cancer:A Multicenter, Single-arm,Phase II Clinical Trial

Metastatic Breast Cancer

China

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