Search clinical trials for: Proton pump inhibitor

Total 69738 results

Xijing Hospital of Digestive Diseases

Enrolling by invitation

Helicobacter Rescue Therapy With High-dose Esomeprazole and Amoxicillin Dual Therapy Versus Bismuth-containing Quadruple Therapy

Gastritis | Dyspepsia | Gastric Cancer | Peptic Ulcer | Helicobacter Pylori Infection

China
Fatih Sultan Mehmet Training and Research Hospital

Completed

THE EFFECT OF HELICOBACTER PYLORI ERADICATION THERAPY TO GASTRIC WALL THICKNESS BEFORE THE LAPAROSCOPIC SLEEVE GASTRECTOMY

Obesity, Morbid | Helicobacter Pylori Infection

Turkey
University Health Network, Toronto

Completed

Pantoprazole and Docetaxel for Men With Metastatic Castration-Resistant Prostate Cancer

Prostate Cancer

Canada
IRCCS Azienda Ospedaliero-Universitaria di Bologna

Completed

Sequential Therapy Versus Triple Therapy for Helicobacter Pylori Eradication: a Placebo-controlled Trial

Helicobacter Pylori Infection

Italy
Wroclaw Medical University

Active, not recruiting

The Role of HRM and Specific Biomarkers of Inflammation in the Diagnosis of Patients With Dysphagia and Suspected EoE

Eosinophilic Esophagitis

Poland
Hoffmann-La Roche

Completed

A Study to Investigate the Effect of Esomeprazole and the Effect of Food on the Pharmacokinetics of Balovaptan in Healthy Volunteers

Autism Spectrum Disorder

United States
Rigshospitalet, Denmark

Terminated

Stereotactic Radiosurgery in Metastatic Spinal Cord Compression (Stereocord)

Neoplasm Metastasis | Spinal Cord Compression

Denmark
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Study Of Celecoxib Or Diclofenac And Omeprazole For Gastrointestinal (GI) Safety In High GI Risk Patients With Arthritis (CONDOR)

Arthritis, Rheumatoid | Osteoarthritis

Canada, Costa Rica, France, Korea, Republic of, Spain, Ukraine, Croatia, Taiwan, China, Serbia, Brazil, Singapore, Belgium, India, Colombia, Netherlands, Russian Federation, United Kingdom, Estonia, Portugal, Sweden, Hong Kong, Latvia, South Africa and more
XenoPort, Inc.

Completed

A Study to Evaluate the Efficacy and Safety of Arbaclofen Placarbil (XP19986) as Adjunctive Therapy in Subjects With Gastroesophageal Reflux Disease (GERD)

Gastroesophageal Reflux Disease

United States, Canada
King Chulalongkorn Memorial Hospital

Completed

Rapid Urease Test for Helicobacter Pylori in Population Who Stop Proton Pump Inhibitor Less Than 2 Weeks Compared With Histology

Helicobacter Pylori Infection

Thailand
Universitaire Ziekenhuizen KU Leuven
MY HEALTH

Completed

Effect of Sporebiotics in FD

Dyspepsia | Dysbiosis

Belgium
Mackay Memorial Hospital

Completed

Intraluminal Mono-antibiotic Therapy for Helicobacter Pylori Infection - A Comparison of Levofloxacin Powder and Levofloxacin Solution

Helicobacter Pylori Infection

Taiwan
AstraZeneca
Acerta Pharma, LLC

Completed

A Study to Evaluate Relative Bioavailability, Proton Pump Inhibitor (PPI) (Rabeprazole) Effect, Food Effect and Particle Size Effect of New Acalabrutinib Tablet in Healthy Subjects

Bioavailability | B-cell Lymphoid Cancer

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Comparison of Small Bowel Lesions Associated With Celecoxib Versus Ibuprofen Plus Omeprazole

Bowel Diseases, Inflammatory

United States
Sir Ganga Ram Hospital

Completed

Helicobacter Pylori Eradication in Functional Dyspepsia

Dyspepsia | Helicobacter Pylori Infection

India
Addpharma Inc.

Completed

A Study to Compare PK, PD and Safety of the AD-206 and Esomeprazole

Gastritis

Korea, Republic of
Dexa Medica Group

Terminated

Efficacy and Safety of DLBS2411 in the Management of GERD

Gastroesophageal Reflux Disease (GERD)

Indonesia
Assiut University

Completed

Esomeprazole in Treatment of Early Onset Preeclampsia (ESOPE Trial)

Preeclampsia

Egypt
Fifth Affiliated Hospital, Sun Yat-Sen University

Unknown

The Effect of PPI in Preventing Gastroesophageal Reflux Disease of Seafarers

Gastroesophageal Reflux Disease
Children's Hospital Srebrnjak
Belupo; University Hospital Center Sisters of Charity, Zagreb, Croatia

Completed

Omeprazole 20 mg in Patients With Laryngopharyngeal reﬂux and Comorbid Chronic Rhinosinusitis

Chronic Rhinosinusitis (Diagnosis) | Laryngopharyngeal Reflux
AstraZeneca
Parexel

Completed

A Study in Healthy Subjects to Assess Bioavailability (Proportion of a Drug Which Enters the Circulation to Have an Active Effect) of Acalabrutinib Tablet and Protonpump Inhibitor Effect (Members of a Class of Medications That Inhibits in Gastric Acid Production) for Rabeprazole

COVID-19 | Mantle Cell Lymphoma

Germany
Millennium Pharmaceuticals, Inc.

Completed

A Study to Assess the Relative Bioavailability, Effect of Food, and Gastric Potential Hydrogen (pH) Modification on the Pharmacokinetics (PK) of TAK-931 in Participants With Advanced Solid Tumors

Neoplasms, Advanced Solid

Netherlands
Shanghai Zhongshan Hospital

Unknown

Bismuth-Metronidazole Triple Therapy for H. Pylori First-line Treatment

Helicobacter Pylori Infection

China
Novartis Pharmaceuticals

Completed

Pharmacokinetic Drug-drug Interaction Study of Dovitinib (TKI258) in Patients With Advanced Solid Tumors

Advanced Solid Tumors, Excluding Breast Cancer

United States
Assistance Publique - Hôpitaux de Paris

Unknown

The Incidence and Risk of Vein Infusion Phlebitis After Intravenous Infusion of Proton Pump Inhibitors (VeinIPP)

Vein Infusion Phlebitis

France
Brooklyn ImmunoTherapeutics, LLC

Completed

A Phase 2 Clinical Trial of the Safety and Effects of IRX-2 in Treating Patients With Operable Head and Neck Cancer

Squamous Cell Carcinoma of the Head and Neck
Fundación Pública Andaluza para la Investigación...

Unknown

Response to Oral Lansoprazole of Inorganic Pyrophosphate Levels in Patients With Grönblad-Stranberg Disease (Pseudoxanthoma Elasticum) (FIMPXE2016-01)

Grönblad-Stranberg Disease (Pseudoxanthoma Elasticum)

Spain
Novartis Pharmaceuticals

Completed

Evaluate the Effects of Patupilone on the Pharmacokinetics of Midazolam and Omeprazole in Patients With Advanced Malignancies

Solid Tumors

United States
Radboud University Medical Center
Merck Sharp & Dohme LLC

Completed

Pharmacokinetic Study of the HCV Protease Inhibitor Bo-cePRevir and the Proton Pump Inhibitor OMeprazOle (PROMO) (PROMO)

HCV Infections | Gastric Acid-related Disorders

Netherlands
Hanmi Pharmaceutical Company Limited

Completed

Efficacy and Safety of HIP1601 Capsule

Erosive Gastroesophageal Reflux Disease

Korea, Republic of
Kaohsiung Veterans General Hospital.

Completed

Comparing the Efficacy of Reverse Hybrid Therapy and Concomitant Therapy

Helicobacter Pylori Infection

Taiwan
Icahn School of Medicine at Mount Sinai

Withdrawn

Whether Proton Pump Inhibitors, Administered Prior to or After Surgery, Can Reduce the Incidence and/or Severity of Difficulty Swallowing Foods and/or Liquids,Following Anterior Cervical Surgery

Dysphagia | GERD | Degenerative Joint Disease

United States
EndoGastric Solutions

Completed

The EndoGastric Solutions TEMPO Trial (TEMPO)

Gastroesophageal Reflux Disease (GERD)

United States
Boston Pharmaceuticals

Completed

Study to Determine the Single and Repeat Dose Pharmacokinetics, Food Effect, Proton Pump Inhibitor (PPI) Drug Interaction, Safety and Tolerability of Oral Prototype Formulations of BOS172767 in Healthy Subjects

Healthy Subjects

United Kingdom
Janssen Research & Development, LLC

Completed

A Study to Assess the Effects of Acid-Reducing Agent(s) on JNJ-64417184 in Healthy Participants

Healthy Participants

Netherlands
University of Split, School of Medicine

Completed

Quadruple vs Tailored Therapy in the Treatment of Helicobacter Pylori Infection

Helicobacter Pylori Infection

Croatia
Al-Azhar University
Ministry of Health, Kuwait

Completed

Comparing Different Regimens for Eradication of Helicobacter Pylori in Kuwait

Helicobacter Pylori Infection
Ahmad Nassar Ibrahim
Assiut University

Unknown

Knowledge, Attitude and Practice of Physicians Toward The Prescription of Proton Pump Inhibitors in Egypt

Knowledge, Attitudes, Practice
University of Sao Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Pharmacogenetic and Pharmacokinetics of Naproxen and Associated Naproxen-esomeprazole

Poor Metabolizer Due to Cytochrome P450 CYP2C9 Variant | Poor Metabolizer Due to Cytochrome p450 CYP2C19 Variant

Brazil
Bristol-Myers Squibb

Completed

A Study to Investigate the Effects of Gastric Acid Suppression by Rabeprazole and BMS-986165 on How Fast and Complete The Drug is Absorbed Into the Body of Healthy Participants

Healthy

Netherlands
AstraZeneca
Acerta Pharma BV

Completed

A Study to Evaluate Effects of Proton-pump Inhibitor on Acalabrutinib Capsule When Administered Orally With COCA-COLA in Healthy Participants

Infectious Disease

United States
Takeda

Withdrawn

Phase 4, Vedolizumab-4002 Post-marketing, Disease-Drug-Drug Interaction Study

Crohn Disease | Colitis, Ulcerative

United States
LEO Pharma

Completed

Drug-drug Interaction Trial With Tralokinumab in Moderate to Severe Atopic Dermatitis - ECZTRA 4

Atopic Dermatitis

United States, France, Netherlands
Samsung Changwon Hospital

Unknown

Efficacy of Low Dose Intravenous Proton Pump Inhibitor for Peptic Ulcer Bleeding

Peptic Ulcer | Peptic Ulcer Hemorrhage | Peptic Ulcer, Acute With Hemorrhage | Proton Pump Inhibitor Overdose

Korea, Republic of
Radboud University Medical Center

Completed

Influence of Cola on the Absorption of the HCV Agent Velpatasvir in Combination With PPI Omeprazole. (COPA)

Hepatitis C | Swallowing Disorder

Netherlands
Changi General Hospital

Unknown

A RCT of Triple Therapy With Proton Pump Inhibitor vs Vonoprazan for Helicobacter Pylori Gastritis (TRIVON)

Helicobacter Pylori Infection

Singapore
Universitaire Ziekenhuizen KU Leuven

Completed

PPI and Microbiome in Healthy Volunteers and Functional Dyspepsia

Dysbiosis

Belgium
Kaohsiung Veterans General Hospital.

Unknown

Comparing the Efficacy of 10-day Reverse Hybrid Therapy and 10-day Triple Therapy Plus Bismuth Therapy.

Helicobacter Pylori Infection

Taiwan
Boryung Pharmaceutical Co., Ltd

Completed

A Multi-center, Randomized, Double-blind Phase III Clinical Trial to Assess and Compare to the Efficacy and Safety of Lafutidine, Famotidine and Omeprazole-referenced in Korean Erosive Esophagitis Patients

Erosive Esophagitis
Damascus Hospital

Completed

Comparing Efficacy of 14-day Therapy Doxycycline With Bismuth Subsalicylate Versus Levofloxacin With Tinadizole on Treatment Helicobacter Pylori

Helicobacter Pylori Infection

Syrian Arab Republic

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