Search clinical trials for: Trace amine-associated receptor 1 (TAAR1) agonist

Total 66795 results

Andrzej Frycz Modrzewski Krakow University
Karolinska Institutet; University of Rzeszow

Completed

Polish Validation 4AT Tool

Delirium, Postoperative | Surgical Procedure

Poland
Activ'inside
CIC Inserm 1405, University Hospital Clermont-Ferrand, France

Completed

Bioavailabity of the Major Metabolites of a Botanical Extract, in Healthy Adults

Healthy

France
Rajesh Deshar

Completed

Effect of Glycopyrrolate on Vasopressors Requirement for Non-elective Caesarean Section Under Spinal Anaesthesia

Hemodynamic Instability | Effect of Drug | Post-spinal Hypotension | Glycopyrrolate

Nepal
ANRS, Emerging Infectious Diseases
Pfizer

Completed

Immuno-stimulation With Maraviroc Combined to Antiretroviral Therapy in Advanced Late Diagnosed HIV-1 Infected Patients (OPTIMAL)

HIV-1 Infection | AIDS

France
Tobira Therapeutics, Inc.

Completed

Efficacy, Safety, and Tolerability of Cenicriviroc (CVC) in Combination With Truvada or Sustiva Plus Truvada in HIV 1-infected, Antiretroviral Treatment-naïve, Adult Patients Infected With Only CCR5-tropic Virus

HIV-1 Infection

United States, Puerto Rico
Hospital Clinic of Barcelona

Unknown

Effect of Maraviroc (MCV) on the Immunological Recovery of HIV-1 Discordant Patients With CD4 Lymphocyte Counts Below 200 Cells/mm3 (DIS-MVC)

HIV-1 Infection

Spain
Fundación Huésped
Pfizer

Unknown

Maraviroc (Celsentri) With Raltegravir and Darunavir/Ritonavir for the Treatment of Triple Class Failure in Adult HIV-1 Infected Patients (TERCETO)

AIDS | HIV-1 Adults Patients | Triple Class Failure

Argentina
Haruhiko Fukuda
Ministry of Health, Labour and Welfare, Japan

Completed

A Study Comparing Irinotecan and Cisplatin (IP) With Etoposide and Cisplatin (EP) Following EP/TRT for LD-SCLC

Small-Cell-Lung Cancer

Japan
Eli Lilly and Company

Recruiting

A Drug-Drug Interaction (DDI) Study of Orforglipron With Carbamazepine in Healthy Participants

Healthy

United States
Eli Lilly and Company

Recruiting

A Study of LY3938577 in Healthy Participants and Participants With Type 1 Diabetes Mellitus (T1DM)

Healthy | Type 1 Diabetes Mellitus

Germany
Eli Lilly and Company

Completed

A Study of LY3461767 in Participants With Chronic Heart Failure With Reduced Ejection Fraction

Chronic Heart Failure With Reduced Ejection Fraction

United States, Japan
Eli Lilly and Company

Active, not recruiting

A Study of (LY3650150) Lebrikizumab to Assess the Safety and Efficacy of Adult and Adolescent Participants With Moderate-to-Severe Atopic Dermatitis and Skin of Color (ADmirable)

Atopic Dermatitis

United States
Eli Lilly and Company

Completed

A Study of LY3841136 in Healthy and Overweight Participants

Healthy | Obesity

United States
Eli Lilly and Company

Completed

A Study of Imlunestrant (LY3484356) in Female Participants With Impaired Liver Function

Hepatic Insufficiency | Healthy

United States
Eli Lilly and Company

Completed

A Drug Drug Interaction (DDI) Study of Selpercatinib (LY3527723) and Rosuvastatin in Healthy Participants

Healthy

United States
Eli Lilly and Company

Completed

A Chronic Pain Master Protocol (CPMP): A Study of LY3857210 in Participants With Chronic Low Back Pain

Chronic Low-back Pain

United States, Puerto Rico
Eli Lilly and Company

Not yet recruiting

Lebrikizumab Pen Ease of Use in Participants With Atopic Dermatitis

Atopic Dermatitis

United States
Bright Future Pharmaceuticals Factory O/B Bright...
Chinese University of Hong Kong

Completed

Clinical Bioequivalence Study on Two Methyldopa Tablet 250mg Formulations

Healthy

Hong Kong
Ono Pharmaceutical Co. Ltd

Active, not recruiting

Study of ONO-4578 With and Without ONO-4538 in Subjects Advanced or Metastatic Solid Tumors

Advanced or Metastatic Solid Tumors

Japan
Sanofi

Completed

GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of Sulfonylurea (GETGOAL-S)

Diabetes Mellitus, Type 2

United States, Romania, Russian Federation, Germany, Netherlands, Turkey, Bulgaria, India, Taiwan, Czech Republic, Tunisia, Japan, Egypt, Israel, Korea, Republic of, Thailand
University of California, Irvine
Juvenile Diabetes Research Foundation

Completed

PET-CT Scan Method to Monitor Pancreatic B-Cell Loss in Diabetes Mellitus

Type1 Diabetes Mellitus

United States
Hacettepe University

Not yet recruiting

Body Awareness and Mental Fatigue in Neck Pain

Mental Fatigue | Neck Pain | Mindfulness | Awareness

Turkey
Celgene

Completed

A Study to Evaluate the Relative Bioavailability of a Pediatric Granule Formulation of Ozanimod in Healthy Adult Subjects

Healthy Volunteers

United States
Celgene

Completed

Drug-drug Interaction Study of Ozanimod With Tyramine to Evaluate the Effect on Pressor Response

Healthy Volunteer

United States
McNeil AB
Janssen (China) Research & Development Center

Completed

Clinical Study to Assess Bioequivalence Between Nicorette Extra Mint Gum and Nicorette® Mint Gum in Healthy Smokers

Tobacco Dependence

China
Eisai Inc.

Completed

Study to Evaluate the Efficacy and Safety of Eribulin Mesylate Administered Biweekly (Q2W) for Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Negative Metastatic Breast Cancer

Breast Cancer

United States
Bispebjerg Hospital
Odense University Hospital; Zealand University Hospital; Hvidovre University... and other collaborators

Recruiting

Danish Trial of Beta Blocker Treatment After Myocardial Infarction Without Reduced Ejection Fraction (DANBLOCK)

ST Elevation Myocardial Infarction | Acute Myocardial Infarction | Non-ST Elevation Myocardial Infarction (nSTEMI)

Denmark
Lixia Sheng

Not yet recruiting

Clinical Study of OR for Second-line Treatment of Refractory MZL

OR Regimen Refractory Marginal Zone Lymphoma
Assistance Publique - Hôpitaux de Paris

Completed

Endothelial Dysfunction and Diabetes (DENDI)

Type 1 Diabetes Mellitus

France
Handok Inc.
CMG Pharmaceutical Co. Ltd

Completed

A Phase 1 Study of NOV1601(CHC2014) in Adult Subjects With Solid Organ Malignancies

Solid Tumor, Adult | Phase 1

Korea, Republic of
University of Copenhagen

Completed

GLP-1 Response and Effect in Individuals With Obesity Causing Genetic Mutations

Obesity

Denmark
R-Pharm
Almedis

Completed

Pharmacokinetic Equivalence and Safety Study of RPH-001 and Avastin®

Healthy

Russian Federation
Sanofi

Completed

GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation in Monotherapy (GETGOAL-MONO Japan LTS) (GETGOAL-MONO)

Diabetes Mellitus, Type 2

Japan
Sanofi

Completed

GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of Metformin (GETGOAL-F1)

Diabetes Mellitus, Type 2

United States, Brazil, Poland, Romania, Ukraine, Germany, Italy, Estonia, Malaysia, Philippines, Mexico, Lithuania, Colombia, Slovakia, Chile
Sanofi

Completed

GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation in Monotherapy (GETGOAL-MONO)

Diabetes Mellitus, Type 2

United States, Poland, Romania, Russian Federation, Ukraine, India, Belgium, Mexico, Tunisia, Japan, Israel, Korea, Republic of
University of Florence

Completed

Oral Contraceptive Therapy and Sexuality (COSEX)

Mental Health Wellness 1 | Sexual Behavior | Contraceptive Usage

Italy
Pfizer

Terminated

A Phase 2B Multicenter, Randomized, Comparative Trial Of UK-453,061 Versus Etravirine In Combination With Darunavir/Ritonavir And A Nucleos(t)Ide Reverse Transcriptase Inhibitor For The Treatment Of Antiretroviral Experienced HIV-1 Infected Subjects With Evidence Of NNRTI Resistant HIV-1

HIV-1

Spain, United Kingdom, Malaysia, United States, Portugal, Brazil, Germany, Italy, Poland, Puerto Rico, South Africa, Taiwan, Ukraine
University of Oxford
Medical Research Council

Terminated

Safety and Immunogenicity of MVA.HIVconsv in HIV-1 Seropositive Adults on HAART

HIV-1

United Kingdom
Christoph Stephan
University Hospital Heidelberg

Completed

Impact of Raltegravir on HIV-1 cDNA Slope Following Antiretroviral Therapy (ART) Initiation

HIV-1

Germany
Tibotec Pharmaceuticals, Ireland

Completed

The TMC125-C214 Study Provides Early Access to TMC125 for HIV-1 Infected Patients Who Have Failed Multiple Antiretroviral Regimens and Will Also Gather Information on the Long-term Safety and Tolerability of TMC125 Combined With Other Antiretroviral Drugs

HIV-1

United States, Belgium, Germany, Taiwan, Spain, Mexico, Turkey, Canada, Netherlands, Denmark, Greece, Sweden, Korea, Republic of, Russian Federation, Puerto Rico, Luxembourg
Juan A. Arnaiz

Completed

Metabolic Effects of Atazanavir/Ritonavir Versus Darunavir/Ritonavir in Combination With Tenofovir/Emtricitabine in naïve HIV-1 Infected Patients

HIV-1

Spain
GlaxoSmithKline

Terminated

Open Label Study of 908/RTV in Combination With Other PIs for the Treatment of Multi PI-Experienced HIV Subjects

HIV-1

Australia, Belgium, Canada, France, Germany, Greece, Italy, Spain, United Kingdom
Suven Life Sciences Limited

Completed

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of SUVN-911 in Healthy Subjects (SUVN-911)

Depressive Disorder, Major

United States
The University of Hong Kong

Completed

Comparison of Two Doses of Intranasal Dexmedetomidine as Premedication in Children

Patient Between 1-8 Years Old Undergoing Elective Surgery at Queen Mary Hospital

Hong Kong
University of Florida

Recruiting

Lung Disease and Its Affect on the Work of White Blood Cells in the Lungs

Alpha-1 Antitrypsin Deficiency | Cystic Fibrosis (CF) | AATD | AAT Deficiency

United States
University of Colorado, Denver

Completed

Regadenoson Blood Flow in Type 1 Diabetes (RABIT1D) (RABIT1D)

Coronary Artery Disease | Type 1 Diabetes Mellitus

United States
University of Pennsylvania

Completed

Sexual and Gender Minority Emerging Adults Eliciting Narratives (SEEN)

Mental Health Wellness 1 | Gender Identity | Sexual Orientation

United States
Vakif Gureba Training and Research Hospital

Completed

Cross-Education Of Contralateral Antagonists

Muscle Strength Quantitative Trait Locus 1
Momenta Pharmaceuticals, Inc.

Completed

Assessment of Pharmacokinetics and Safety of M923 Administered Via Auto-injector or Prefilled Syringe, in Healthy Subjects

Healthy

United States, United Kingdom
Dompé Farmaceutici S.p.A

Active, not recruiting

A Study of Oral Ladarixin in Recent Onset Type 1 Diabetes and a Low Residual β-cell Function

New-onset type1 Diabetes

United States, Belgium, Georgia, Germany, Italy, Serbia, Israel, Slovenia

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