Search clinical trials for: Two-way crossover

Total 899 results

AstraZeneca

Completed

A Study to Evaluate Bioavailability and Food Effect of Selumetinib (AZD6244) in Healthy Male Participants

Healthy Participants | Neurofibromatosis Type 1 (NF1)-Related Plexiform Neurofibromas (PNs)

United States
Merck Sharp & Dohme LLC

Completed

Phase IIB 2-Period Crossover Polysomnography Study in Participants With Primary Insomnia (MK-4305-006)

Primary Insomnia
Pfizer
Medivation, Inc.

Completed

A Phase 1, Randomized, Open-Label, Two-Way Crossover Study To Evaluate The Steady-State Effect Of Dimebon (PF 01913539) On The Single-Dose Pharmacokinetics And Pharmacodynamics Of Warfarin In Healthy Subjects

Alzheimer's Disease | Huntington's Disease

United States
Pfizer

Completed

A Randomized, Two-way, Crossover Study to Estimate the Relative Bioavailability of a Controlled-release Formulation of Oxycodone (40 mg) With Sequestered Naltrexone Compared With Immediate-release Oxycodone Tablets (20 mg) in Healthy Volunteers

Healthy

United States
Universidade Federal de Goias

Completed

Attachment Types for Single-implant Mandibular Overdentures: a Crossover Clinical Trial (SIMODA)

Complete Edentulism | Edentulous Mouth
Oregon Health and Science University

Completed

Four Way Crossover Closed Loop With Exercise Detection

Type 1 Diabetes

United States
Lung Institute

Withdrawn

Crossover Blinded Trial of Cell Therapy Versus Placebo in COPD

COPD | Chronic Bronchitis | Emphysema or COPD

United States
Wake Forest University
LEO Pharma

Completed

Patient Preference of Taclonex Ointment to Taclonex Scalp Suspension in Adult Subjects With Psoriasis Vulgaris (PSTaclonex)

Plaque Psoriasis

United States
Swinburne University of Technology

Completed

Cognition Effects of Hearing Aids and Auditory Training in Older Age

Hearing Loss, Sensorineural

Australia
NeoTract, Inc.

Completed

The Safety and Effectiveness of UroLift: LIFT Pivotal Study (LIFT)

Benign Prostatic Hyperplasia

United States, Australia, Canada
Centre Hospitalier Universitaire Dijon

Completed

Monocentric Pilot Study, for a Randomized, Crossover, Blinded Trial: Comparison of the Therapeutic Efficacy of Low Frequency Repeated Transcranial Magnetic Stimulation on Cortical Area 9 Compared to Brodmann Area 46 in the Treatment of Depressive Disorders. (rTMS)

Patients With Resistant Depressive Disorders

France
Maria Sklodowska-Curie National Research Institute...

Completed

Randomized Trial of G-CSF Alone Versus Intermediate-dose Ara-C Plus G-CSF Mobilization in Multiple Myeloma Patients.

Multiple Myeloma

Poland
Yonsei University

Completed

A Crossover Trial of Chitosan Oligosaccharide on Post Prandial Glucose Control in Subjects With Normal, IFG and IGT

Impaired Glucose Tolerance | Impaired Fasting Glucose | Normal

Korea, Republic of
Trius Therapeutics LLC

Completed

A Phase 1 Crossover Study of Blood Pressure and Heart Rate Response

Healthy Subjects

United States
AstraZeneca
Parexel

Completed

A Study to Assess How Much Drug Reaches the Blood When Given From Symbicort pMDI With Spacer Compared to That of Symbicort pMDI Without Spacer in Healthy Volunteers

Study is Being Conducted in Healthy Volunteers

United Kingdom
Chengappa, K.N. Roy, MD
National Institutes of Health (NIH)

Completed

Test of Novel Drug for Smoking Cessation (UH3-P2)

Smoking Cessation

United States
Innosparks Pte Ltd.
National University Hospital, Singapore; KK Women's and Children's Hospital

Completed

A Randomised Crossover Study to Explore the Physiological Impact of AIR+ Smart Masks on Children

Healthy Subjects

Singapore
Novartis Pharmaceuticals

Completed

A Multicenter, 4-week Crossover (Total Duration 12 Weeks) to Determine the Impact of QVA149 on Nocturnal Oxygen Levels in Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

Sweden, Denmark, Norway
Pfizer

Completed

A Single Dose Crossover Study In Healthy Subjects To Evaluate Different Formulations Of PF-06882961

Healthy Subjects

United States
Janssen Research & Development, LLC

Terminated

A Crossover Study to Assess the Drug-drug Interaction of Acid Reducing Agent(s) on the Pharmacokinetics of a Single Oral Dose of Lumicitabine (JNJ-64041575) in Healthy Adult Participants

Healthy

Belgium
Agile Therapeutics

Completed

Study to Evaluate the Contraceptive Efficacy/Safety of a Low Dose EE/LNG Transdermal Contraceptive Delivery System

Contraception

United States
University of Rochester

Completed

Pilot Study of Feasibility of Outpatient Daily High Dose Cytarabine as Consolidation Therapy for Older Patients With Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia

United States
GlaxoSmithKline

Completed

Bioavailability of Two Combination Products of Dutasteride (0.5mg) and Tamsulosin Hydrochloride (0.2mg) in Asian Males. (ARI115707)

Prostatic Hyperplasia

Australia
GlaxoSmithKline

Completed

Repeat Dose Study of Controlled-Release Paroxetine Tablets and Immediate-Release Paroxetine Tablets in Healthy Japanese Male Subjects

Depressive Disorder

Japan
GlaxoSmithKline

Completed

Study to Compare the Bioavailability of Dutasteride Novel Formulation Form to the Soft Gel Capsule Form in Healthy Male Subjects (ARI115148)

Prostatic Hyperplasia

United States
GlaxoSmithKline

Completed

A Study Assessing a Range of Formulations of the Fixed Dose Combination Product Containing Dutasteride (0.5mg) and Tamsulosin Hydrochloride (0.2mg) to Find a Formulation Which is Bioequivalent to Harnal-D Tablets (Tamsulosin Hydrochloride, 0.2mg) in Healthy Male Subjects From North East Asia

Prostatic Hyperplasia

Australia
GlaxoSmithKline

Completed

Crossover Study to Evaluate the Pharmacokinetics of Ezogabine/Retigabine in Taiwanese Subjects

Epilepsy

Taiwan
GlaxoSmithKline

Completed

Comparative Bioavailability of Two Fixed Dose Combination (FDC) Formulations of Dutasteride and Tamsulosin Hydrochloride Relative to Co-administration of Dutasteride With Tamsulosin Hydrochloride in Healthy Male Subjects Under Fed and Fasted States

Prostatic Hyperplasia

United States
Embera NeuroTherapeutics, Inc.
National Institute on Drug Abuse (NIDA)

Completed

Single Dose Crossover Comparative Bioavailability and Food Effect Study of Two EMB-001 Formulations

Cocaine Use Disorder

United States
Janssen Research & Development, LLC

Completed

A Crossover Study to Assess the Effect of Intravenous Infusion of Piperacillin/Tazobactam on the Pharmacokinetics of Orally Administered Lumicitabine (JNJ-64041575) in Healthy Adult Participants

Healthy

Belgium
Veloxis Pharmaceuticals

Completed

Crossover Study to Compare PK of Once Daily LCP-Tacro Tablets to Generic Tacrolimus Capsules Twice Daily.

Renal Failure

United States
Amphastar Pharmaceuticals, Inc.

Terminated

Randomized, Placebo/Active Crossover Dose-ranging Study for Safety and Efficacy in Asthma Patients.

Asthma

United States
University of Washington
University of Nairobi; Kenyatta National Hospital

Completed

Evaluation of an mHealth SMS Dialogue Strategy to Meet Women's and Couples' Postpartum Contraceptive Needs in Kenya (Mobile WACh XY)

Contraception | Postpartum Period

Kenya
National Cancer Institute (NCI)

Completed

Crossover Vaccination of Women Previously Randomized Into Protocol 04-C-N191

Cervical Neoplasia | HPV Infections

Costa Rica
Depomed

Completed

Open Label Crossover Study Pharmacokinetics (PK) Study in Healthy Volunteers Receiving Various Forms of Fentanyl

Healthy
GlaxoSmithKline

Withdrawn

A Bioequivalence Study of SKF101804 Cefixime Versus Cefixime Reference Formulation in Healthy Adults Under Fasting Conditions

Infections, Bacterial
MedtronicNeuro

Terminated

CONCEPT: Crossover Efficacy Pain Trial in Motor Cortex Stimulation for Intractable Neuropathic Pain

Facial Pain | Pain, Intractable

Austria, Germany, Belgium, Spain
Corcept Therapeutics

Completed

Crossover Drug-Drug Interaction Study to Determine Effects of Cytochrome P450 3A on Exposure to Mifepristone and Its Metabolites

Healthy

United States
AstraZeneca
Biocard

Completed

An Open-label, Randomized, Crossover Study of Comparative Pharmacokinetics and Bioequivalence of Dapagliflozin + Metformin, 10 mg + 1000 mg Versus the Combined Use of Forxiga™, 10 mg and Two Glucophage® Long, ER Tablets, 500 mg Co-administered to Healthy Volunteers Under Standard Fed Conditions

Diabetes Mellitus, Type 2

Russian Federation
Seberang Jaya Clinical Research Centre
Universiti Sains Malaysia; Clinical Research Centre Hospital Taiping

Unknown

Stroke and Tocotrienol: Unique Role in Neuroprotection (SATURN)

Ischemic Stroke

Malaysia
Nationwide Children's Hospital

Completed

Methadone vs Magnesium in Spinal Fusion

Idiopathic Scoliosis

United States
Cerus Corporation

Terminated

A Randomized, Multi-center, Open-label, Paired Controlled, Crossover In Vivo Study

Healthy

United States
Chinese Academy of Sciences

Completed

The Intervention Study of Dietary Intake on Energy Expenditure

Healthy and Overweight/ Obesity Males

China
Roxane Laboratories

Completed

Crossover Bioequivalence Study of Irbesartan HCTZ 300/25 mg Tablets Under Fasted Conditions

Hypertension

United States
Roxane Laboratories

Completed

Crossover Bioequivalence Study of Oxcarbazepine 600 mg Suspension Under Fed Conditions

Seizures

United States
Roxane Laboratories

Completed

Crossover Bioequivalence Study of Oxcarbazepine 600 mg Suspension Under Fasted Conditions

Seizures

United States
Roxane Laboratories

Completed

A Single Dose, 2-Period, 2-Treatment, 2-Way Crossover Bioequivalency Study of Ropinirole 0.25 mg Tablets Und Fasted Conditions

Parkinson's Disease | Restless Leg Syndrome
Roxane Laboratories

Completed

A Single Dose, 2-Period, 2-Treatment, 2-Way Crossover Bioequivalency Study of Balsalazide Disodium 750 mg Capsules Under Fasting Conditions

Ulcerative Colitis

United States
Roxane Laboratories

Completed

Crossover Bioequivalence Study of Cevimeline 30 mg Capsules Under Fasted Conditions

Dry Mouth

United States
Roxane Laboratories

Completed

Crossover Bioequivalence Study of Quetiapine Fumarate 300 mg Tablets Under Steady State Fasted Conditions

Bipolar I Disorder

United States

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